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New formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations
Author / Creator:Abdelhalim, Walaa Ali ; Rabee, Ahmed R. ; Soliman, Saied M. ; Hagar, Mohamed ; Moneer, Esraa A. ; Bakr, Basant A. ; Barakat, Assem ; Haukka, Matti ; Rasheed, Hanaa A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.299-12, Article 299
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Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3-a]quinazolin-9-ones and Their Antiproliferative Action
Author / Creator:Said, Awad I. ; Gajdács, Márió ; Zupkó, István ; Haukka, Matti ; Palkó, Márta
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (9), p.3718
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Synthesis and Structure Elucidation of Novel Spirooxindole Linked to Ferrocene and Triazole Systems via [3 + 2] Cycloaddition Reaction
Author / Creator:Altowyan, Mezna Saleh ; Soliman, Saied M. ; Haukka, Matti ; Al-Shaalan, Nora Hamad ; Alkharboush, Aminah A. ; Barakat, Assem
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-07, Vol.27 (13), p.4095
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Exploiting the Chiral Ligands of Bis(imidazolinyl)- and Bis(oxazolinyl)thiophenes—Synthesis and Application in Cu-Catalyzed Friedel–Crafts Asymmetric Alkylation
Author / Creator:Islam, Mohammad Shahidul ; Alammari, Abdullah Saleh ; Barakat, Assem ; Alshahrani, Saeed ; Haukka, Matti ; Al-Majid, Abdullah Mohammed
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-12, Vol.26 (23), p.7408
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Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs
Author / Creator:Barakat, Assem ; Haukka, Matti ; Soliman, Saied M. ; Ali, M. ; Al-Majid, Abdullah Mohammed ; El-Faham, Ayman ; Domingo, Luis R.
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-11, Vol.26 (23), p.7276
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Angular Regioselectivity in the Reactions of 2-Thioxopyrimidin-4-ones and Hydrazonoyl Chlorides: Synthesis of Novel Stereoisomeric Octahydro[1,2,4]triazolo[4,3-a]quinazolin-5-ones
Author / Creator:Said, Awad I. ; Palkó, Márta ; Haukka, Matti ; Fülöp, Ferenc
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-12, Vol.25 (23), p.5673
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Stereoselective synthesis and transformation of pinane-based 2-amino-1,3-diols
Author / Creator:Bajtel, Ákos ; Raji, Mounir ; Haukka, Matti ; Fülöp, Ferenc ; Szakonyi, Zsolt
Publisher:Frankfurt am Main: Beilstein-Institut zur Föerderung der Chemischen Wissenschaften
Journal title:Beilstein journal of organic chemistry, 2021-05, Vol.17 (1), p.983-990
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New spiro-indeno[1,2- b ]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insigh...
Author / Creator:Barakat, Assem ; Alshahrani, Saeed ; Al-Majid, Abdullah Mohammed ; Alamary, Abdullah Saleh ; Haukka, Matti ; Abu-Serie, Marwa M. ; Domingo, Luis R. ; Ashraf, Sajda ; Ul-Haq, Zaheer ; Nafie, Mohamed S. ; Teleb, Mohamed
Publisher:England: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2281260
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A New Pt(II) Complex with Anionic s-Triazine Based NNO-Donor Ligand: Synthesis, X-ray Structure, Hirshfeld Analysis and DFT Studies
Author / Creator:Altowyan, Mezna Saleh ; Soliman, Saied M. ; Lasri, Jamal ; Eltayeb, Naser E. ; Haukka, Matti ; Barakat, Assem ; El-Faham, Ayman
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-03, Vol.27 (5), p.1628
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A Novel Halogen Bond Acceptor: 1-(4-Pyridyl)-4-Thiopyridine (PTP) Zwitterion
Author / Creator:Ding, Xin ; Tuikka, Matti ; Haukka, Matti
Publisher:MDPI AG
Journal title:Crystals (Basel), 2020-03, Vol.10 (3), p.165
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Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation
Author / Creator:Salama, Eid E. ; Youssef, Mohamed F. ; Aboelmagd, Ahmed ; Boraei, Ahmed T. A. ; Nafie, Mohamed S. ; Haukka, Matti ; Barakat, Assem ; Sarhan, Ahmed A. M.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.16 (12), p.1724
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Extended Assemblies of Ru(bpy)(CO)2X2 (X = Cl, Br, I) Molecules Linked by 1,4-Diiodotetrafluoro-Benzene (DITFB) Halogen Bond Donors
Author / Creator:Ding, Xin ; Tuikka, Matti ; Rissanen, Kari ; Haukka, Matti
Publisher:Basel: MDPI AG
Journal title:Crystals (Basel), 2019-06, Vol.9 (6), p.319
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Synthesis of novel fluorinated building blocks via halofluorination and related reactions
Author / Creator:Remete, Attila Márió ; Novák, Tamás T ; Nonn, Melinda ; Haukka, Matti ; Fülöp, Ferenc ; Kiss, Loránd
Publisher:Germany: Beilstein-Institut
Journal title:Beilstein journal of organic chemistry, 2020-10, Vol.16 (1), p.2562-2575
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Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol
Author / Creator:Fekete, Beáta ; Palkó, Márta ; Haukka, Matti ; Fülöp, Ferenc
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2017-04, Vol.22 (4), p.613
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Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascad...
Author / Creator:Shawish, Ihab ; Barakat, Assem ; Aldalbahi, Ali ; Alshaer, Walhan ; Daoud, Fadwa ; Alqudah, Dana A. ; Al Zoubi, Mazhar ; Hatmal, Ma’mon M. ; Nafie, Mohamed S. ; Haukka, Matti ; Sharma, Anamika ; de la Torre, Beatriz G. ; Albericio, Fernando ; El-Faham, Ayman
Publisher:Basel: MDPI AG
Journal title:Pharmaceutics, 2022-07, Vol.14 (8), p.1558
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Synthesis, X-ray Structure, Cytotoxic, and Anti-Microbial Activities of Zn(II) Complexes with a Hydrazono s-Triazine Bearing Pyridyl Arm
Author / Creator:Hassan, MennaAllah ; El-Faham, Ayman ; Barakat, Assem ; Haukka, Matti ; Tatikonda, Rajendhraprasad ; Abu-Youssef, Morsy A. M. ; Soliman, Saied M. ; Yousri, Amal
Publisher:Basel: MDPI AG
Journal title:Inorganics, 2024-07, Vol.12 (7), p.176
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Synthesis, Structure and In Vitro Anticancer Activity of Pd(II) Complex of Pyrazolyl-s-Triazine Ligand; A New Example of Metal-Mediated Hydrolysis of s-Triazine Pincer Ligand
Author / Creator:Lasri, Jamal ; Haukka, Matti ; Al-Rasheed, Hessa H. ; Abutaha, Nael ; El-Faham, Ayman ; Soliman, Saied M.
Publisher:Basel: MDPI AG
Journal title:Crystals (Basel), 2021-02, Vol.11 (2), p.119
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Synthesis, X-ray Single-Crystal Analysis, and Anticancer Activity Evaluation of New Alkylsulfanyl-Pyridazino[4,5-b]indole Compounds as Multitarget Inhibitors of EGFR and Its Downstream PI3K-AKT Pathwa...
Author / Creator:Salama, Eid E. ; Althobaiti, Ibrahim O. ; Haukka, Matti ; Boraei, Ahmed T. A.
Publisher:Basel: MDPI AG
Journal title:Crystals (Basel), 2022-03, Vol.12 (3), p.353
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A New Bromo-Mn(II) Complex with 1,3,5-Triazine Derivative: Synthesis, Crystal Structure, DFT and Biological Studies
Author / Creator:Khattab, Sara M. ; Altowyan, Mezna Saleh ; El-Faham, Ayman ; Barakat, Assem ; Haukka, Matti ; Abu-Youssef, Morsy A. M. ; Soliman, Saied M.
Publisher:Basel: MDPI AG
Journal title:Inorganics, 2024-11, Vol.12 (11), p.284
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Stereoselective Synthesis of New 4-Aryl-5-indolyl-1,2,4-triazole S- and N-β-Galactosides: Characterizations, X-ray Crystal Structure and Hirshfeld Surface Analysis
Author / Creator:Altowyan, Mezna Saleh ; Haukka, Matti ; Soliman, Saied M. ; Barakat, Assem ; Boraei, Ahmed T. A. ; Aboelmagd, Ahmed
Publisher:Basel: MDPI AG
Journal title:Crystals (Basel), 2023-05, Vol.13 (5), p.797
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Showing 1 to 20 of 94 results

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New formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations

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Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3-a]quinazolin-9-ones and Their Antiproliferative Action

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Synthesis and Structure Elucidation of Novel Spirooxindole Linked to Ferrocene and Triazole Systems via [3 + 2] Cycloaddition Reaction

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Exploiting the Chiral Ligands of Bis(imidazolinyl)- and Bis(oxazolinyl)thiophenes—Synthesis and Application in Cu-Catalyzed Friedel–Crafts Asymmetric Alkylation

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Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs

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Angular Regioselectivity in the Reactions of 2-Thioxopyrimidin-4-ones and Hydrazonoyl Chlorides: Synthesis of Novel Stereoisomeric Octahydro[1,2,4]triazolo[4,3-a]quinazolin-5-ones

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Stereoselective synthesis and transformation of pinane-based 2-amino-1,3-diols

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New spiro-indeno[1,2- b ]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insigh...

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A New Pt(II) Complex with Anionic s-Triazine Based NNO-Donor Ligand: Synthesis, X-ray Structure, Hirshfeld Analysis and DFT Studies

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A Novel Halogen Bond Acceptor: 1-(4-Pyridyl)-4-Thiopyridine (PTP) Zwitterion

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Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation

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Extended Assemblies of Ru(bpy)(CO)2X2 (X = Cl, Br, I) Molecules Linked by 1,4-Diiodotetrafluoro-Benzene (DITFB) Halogen Bond Donors

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Synthesis of novel fluorinated building blocks via halofluorination and related reactions

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Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol

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Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascad...

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Synthesis, X-ray Structure, Cytotoxic, and Anti-Microbial Activities of Zn(II) Complexes with a Hydrazono s-Triazine Bearing Pyridyl Arm

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Synthesis, Structure and In Vitro Anticancer Activity of Pd(II) Complex of Pyrazolyl-s-Triazine Ligand; A New Example of Metal-Mediated Hydrolysis of s-Triazine Pincer Ligand

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Synthesis, X-ray Single-Crystal Analysis, and Anticancer Activity Evaluation of New Alkylsulfanyl-Pyridazino[4,5-b]indole Compounds as Multitarget Inhibitors of EGFR and Its Downstream PI3K-AKT Pathwa...

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A New Bromo-Mn(II) Complex with 1,3,5-Triazine Derivative: Synthesis, Crystal Structure, DFT and Biological Studies

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Stereoselective Synthesis of New 4-Aryl-5-indolyl-1,2,4-triazole S- and N-β-Galactosides: Characterizations, X-ray Crystal Structure and Hirshfeld Surface Analysis

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