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ArticlesPeer ReviewedFull Text
Identification of a candidate therapeutic autophagy-inducing peptide
Author / Creator:Shoji-Kawata, Sanae ; Sumpter, Rhea ; Leveno, Matthew ; Campbell, Grant R. ; Zou, Zhongju ; Kinch, Lisa ; Wilkins, Angela D. ; Sun, Qihua ; Pallauf, Kathrin ; MacDuff, Donna ; Huerta, Carlos ; Virgin, Herbert W. ; Helms, J. Bernd ; Eerland, Ruud ; Tooze, Sharon A. ; Xavier, Ramnik ; Lenschow, Deborah J. ; Yamamoto, Ai ; King, David ; Lichtarge, Olivier ; Grishin, Nick V. ; Spector, Stephen A. ; Kaloyanova, Dora V. ; Levine, Beth
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-02, Vol.494 (7436), p.201-206
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Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence
Author / Creator:Arroyo-Olarte, Ruben D. ; Brouwers, Jos F. ; Kuchipudi, Arunakar ; Helms, J. Bernd ; Biswas, Aindrila ; Dunay, Ildiko R. ; Lucius, Richard ; Gupta, Nishith
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2015-11, Vol.13 (11), p.e1002288-e1002288
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The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization
Author / Creator:Sheng, Jie ; Gadella, Bart M. ; Olrichs, Nick K. ; Kaloyanova, Dora V. ; Helms, J. Bernd
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-03, Vol.11 (1), p.5498-5498, Article 5498
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Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins
Author / Creator:Sheng, Jie ; Olrichs, Nick K. ; Gadella, Bart M. ; Kaloyanova, Dora V. ; Helms, J. Bernd
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-09, Vol.21 (18), p.6530
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ER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity
Author / Creator:Kovacevic, Igor ; Schmidt, Paula Henriette ; Kowalski, Annkatrin ; Helms, Bernd J. ; Lest, Chris H. A. van de ; Kluttig, Alexander ; Posern, Guido
Publisher:England: BioMed Central Ltd
Journal title:Cell communication and signaling, 2024-06, Vol.22 (1), p.304-304, Article 304
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Interpreting the lipidome: bioinformatic approaches to embrace the complexity
Author / Creator:Kyle, Jennifer E. ; Aimo, Lucila ; Bridge, Alan J. ; Clair, Geremy ; Fedorova, Maria ; Helms, J. Bernd ; Molenaar, Martijn R. ; Ni, Zhixu ; Orešič, Matej ; Slenter, Denise ; Willighagen, Egon ; Webb-Robertson, Bobbie-Jo M.
Publisher:New York: Springer US
Journal title:Metabolomics, 2021-06, Vol.17 (6), p.55-55, Article 55
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Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation
Author / Creator:Testerink, Nicole ; Ajat, Mokrish ; Houweling, Martin ; Brouwers, Jos F. ; Pully, Vishnu V. ; van Manen, Henk-Jan ; Otto, Cees ; Helms, J. Bernd ; Vaandrager, Arie B.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e34945-e34945
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Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system
Author / Creator:Haaker, Maya W. ; Kruitwagen, Hedwig S. ; Vaandrager, Arie B. ; Houweling, Martin ; Penning, Louis C. ; Molenaar, Martijn R. ; Wolferen, Monique E. ; Oosterhoff, Loes A. ; Spee, Bart ; Helms, J. Bernd
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:Journal of veterinary internal medicine, 2020-01, Vol.34 (1), p.132-138
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SCAP is required for timely and proper myelin membrane synthesis
Author / Creator:Verheijen, Mark H.G ; Camargo, Nutabi ; Verdier, Valerie ; Nadra, Karim ; de Preux Charles, Anne-Sophie ; Médard, Jean-Jacques ; Luoma, Adrienne ; Crowther, Michelle ; Inouye, Hideyo ; Shimano, Hitoshi ; Chen, Su ; Brouwers, Jos F ; Helms, J. Bernd ; Feltri, M. Laura ; Wrabetz, Lawrence ; Kirschner, Daniel ; Chrast, Roman ; Smit, August.B
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (50), p.21383-21388
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ArticlesPeer ReviewedFull Text
Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease
Author / Creator:Molenaar, Martijn R. ; Penning, Louis C. ; Helms, J. Bernd
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-10, Vol.9 (10), p.2244
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Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling
Author / Creator:Krüger, Melanie ; Ruppelt, Alicia ; Kappler, Benjamin ; Van Soest, Elke ; Samsom, Roos Anne ; Grinwis, Guy C. M. ; Geijsen, Niels ; Helms, J. Bernd ; Stijnen, Marco ; Kock, Linda M. ; Rasponi, Marco ; Kooistra, Hans S. ; Spee, Bart
Publisher:Basel: MDPI AG
Journal title:Bioengineering (Basel), 2022-09, Vol.9 (9), p.471
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The fate of porcine sperm CRISP2 from the perinuclear theca before and after in vitro fertilization
Author / Creator:Zhang, Min ; Bromfield, Elizabeth G. ; Helms, J. Bernd ; Gadella, Bart M.
Publisher:United States: Society for the Study of Reproduction
Journal title:Biology of reproduction, 2022-11, Vol.107 (5), p.1242-1253
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ArticlesPeer ReviewedFull Text
Metal ions and redox balance regulate distinct amyloid-like aggregation pathways of GAPR-1
Author / Creator:Sheng, Jie ; Olrichs, Nick K. ; Geerts, Willie J. ; Kaloyanova, Dora V. ; Helms, J. Bernd
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.15048-13, Article 15048
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Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic sus...
Author / Creator:Maric-Biresev, Jelena ; Hunn, Julia P. ; Krut, Oleg ; Helms, J. Bernd ; Martens, Sascha ; Howard, Jonathan C.
Publisher:England: BioMed Central
Journal title:BMC biology, 2016-04, Vol.14 (1), p.33-33, Article 33
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ArticlesPeer ReviewedFull Text
Cholesterol loss during glutamate-mediated excitotoxicity
Author / Creator:Sodero, Alejandro O ; Vriens, Joris ; Ghosh, Debapriya ; Stegner, David ; Brachet, Anna ; Pallotto, Marta ; Sassoè-Pognetto, Marco ; Brouwers, Jos F ; Helms, J Bernd ; Nieswandt, Bernhard ; Voets, Thomas ; Dotti, Carlos G
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2012-04, Vol.31 (7), p.1764-1773
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ArticlesPeer ReviewedFull Text
Direct and GTP-Dependent Interaction of ADP Ribosylation Factor 1 with Coatomer Subunit β
Author / Creator:Zhao, Liyun ; Helms, J. Bernd ; Brugger, Britta ; Harter, Cordula ; Martoglio, Bruno ; Graf, Roland ; Brunner, Josef ; Wieland, Felix T.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (9), p.4418-4423
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Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response
Author / Creator:Houthuijzen, Julia M. ; Daenen, Laura G. M. ; Roodhart, Jeanine M. L. ; Oosterom, Ilse ; van Jaarsveld, Marijn T. M. ; Govaert, Klaas M. ; Smith, Michelle E. ; Sadatmand, Sahar J. ; Rosing, Hilde ; Kruse, Fabian ; Helms, Bernd J. ; van Rooijen, Nico ; Beijnen, Jos H. ; Haribabu, Bodduluri ; van de Lest, Chris H. A. ; Voest, Emile E
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-11, Vol.5 (1), p.5275-5275, Article 5275
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Lipid analysis of Eimeria sporozoites reveals exclusive phospholipids, a phylogenetic mosaic of endogenous synthesis, and a host-independent lifestyle
Author / Creator:Kong, Pengfei ; Lehmann, Maik J. ; Helms, J. Bernd ; Brouwers, Jos F. ; Gupta, Nishith
Publisher:London: Nature Publishing Group UK
Journal title:Cell discovery, 2018-05, Vol.4 (1), p.24-17, Article 24
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ArticlesPeer ReviewedFull Text
Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts
Author / Creator:Van den Bossche, Lindsay ; Schoonenberg, Vivien A. C. ; Burgener, Iwan A. ; Penning, Louis C. ; Schrall, Ingrid M. ; Kruitwagen, Hedwig S. ; van Wolferen, Monique E. ; Grinwis, Guy C. M. ; Kummeling, Anne ; Rothuizen, Jan ; van Velzen, Jeroen F. ; Stathonikos, Nikolas ; Molenaar, Martijn R. ; Helms, Bernd J. ; Brouwers, Jos F. H. M. ; Spee, Bart ; van Steenbeek, Frank G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-10, Vol.12 (10), p.e0186491-e0186491
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ArticlesPeer ReviewedFull Text
Receptor-Induced Polymerization of Coatomer
Author / Creator:Reinhard, Constanze ; Harter, Cordula ; Bremser, Martina ; Brugger, Britta ; Sohn, Kai ; Helms, J. Bernd ; Wieland, Felix
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-02, Vol.96 (4), p.1224-1228
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Identification of a candidate therapeutic autophagy-inducing peptide

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Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence

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The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization

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Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins

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ER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity

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Interpreting the lipidome: bioinformatic approaches to embrace the complexity

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Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

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Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system

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SCAP is required for timely and proper myelin membrane synthesis

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Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease

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Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

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The fate of porcine sperm CRISP2 from the perinuclear theca before and after in vitro fertilization

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Metal ions and redox balance regulate distinct amyloid-like aggregation pathways of GAPR-1

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Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic sus...

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Cholesterol loss during glutamate-mediated excitotoxicity

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Direct and GTP-Dependent Interaction of ADP Ribosylation Factor 1 with Coatomer Subunit β

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Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response

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Lipid analysis of Eimeria sporozoites reveals exclusive phospholipids, a phylogenetic mosaic of endogenous synthesis, and a host-independent lifestyle

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Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts

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Receptor-Induced Polymerization of Coatomer

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