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198 results for Interneurons+-+pathology

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ArticlesPeer ReviewedFull Text
Network abnormalities and interneuron dysfunction in Alzheimer disease
Author / Creator:Palop, Jorge J. ; Mucke, Lennart
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neuroscience, 2016-12, Vol.17 (12), p.777-792
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Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders
Author / Creator:Zhang, Wen ; Zhang, Lifeng ; Liang, Bo ; Schroeder, David ; Zhang, Zhong-wei ; Cox, Gregory A ; Li, Yun ; Lin, Da-Ting
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2016-04, Vol.19 (4), p.557-559
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Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell–derived cortical interneurons from subjects with schizophrenia
Author / Creator:Shao, Zhicheng ; Noh, Haneul ; Bin Kim, Woong ; Ni, Peiyan ; Nguyen, Christine ; Cote, Sarah E. ; Noyes, Elizabeth ; Zhao, Joyce ; Parsons, Teagan ; Park, James M. ; Zheng, Kelvin ; Park, Joshua J. ; Coyle, Joseph T. ; Weinberger, Daniel R. ; Straub, Richard E. ; Berman, Karen F. ; Apud, Jose ; Ongur, Dost ; Cohen, Bruce M. ; McPhie, Donna L. ; Rapoport, Judith L. ; Perlis, Roy H. ; Lanz, Thomas A. ; Xi, Hualin Simon ; Yin, Changhong ; Huang, Weihua ; Hirayama, Teruyoshi ; Fukuda, Emi ; Yagi, Takeshi ; Ghosh, Sulagna ; Eggan, Kevin C. ; Kim, Hae-Young ; Eisenberg, Leonard M. ; Moghadam, Alexander A. ; Stanton, Patric K. ; Cho, Jun-Hyeong ; Chung, Sangmi
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-02, Vol.22 (2), p.229-242
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Assembly of functionally integrated human forebrain spheroids
Author / Creator:Birey, Fikri ; Andersen, Jimena ; Makinson, Christopher D. ; Islam, Saiful ; Wei, Wu ; Huber, Nina ; Fan, H. Christina ; Metzler, Kimberly R. Cordes ; Panagiotakos, Georgia ; Thom, Nicholas ; O’Rourke, Nancy A. ; Steinmetz, Lars M. ; Bernstein, Jonathan A. ; Hallmayer, Joachim ; Huguenard, John R. ; Paşca, Sergiu P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-05, Vol.545 (7652), p.54-59
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Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment
Author / Creator:Meng, Xiangling ; Yao, David ; Imaizumi, Kent ; Chen, Xiaoyu ; Kelley, Kevin W. ; Reis, Noah ; Thete, Mayuri Vijay ; Arjun McKinney, Arpana ; Kulkarni, Shravanti ; Panagiotakos, Georgia ; Bassik, Michael C. ; Pașca, Sergiu P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-10, Vol.622 (7982), p.359-366
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Interneuron dysfunction in psychiatric disorders
Author / Creator:MARIN, Oscar
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neuroscience, 2012-02, Vol.13 (2), p.107-120
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Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy
Author / Creator:Tewari, Bhanu P. ; Chaunsali, Lata ; Campbell, Susan L. ; Patel, Dipan C. ; Goode, Adam E. ; Sontheimer, Harald
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.4724-17, Article 4724
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Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder
Author / Creator:Anderson, Kevin M. ; Collins, Meghan A. ; Kong, Ru ; Fang, Kacey ; Li, Jingwei ; He, Tong ; Chekroud, Adam M. ; Yeo, B. T. Thomas ; Holmes, Avram J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (40), p.25138-25149
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XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
Author / Creator:Hoch, Nicolas C. ; Hanzlikova, Hana ; Rulten, Stuart L. ; Tétreault, Martine ; Komulainen, Emilia ; Ju, Limei ; Hornyak, Peter ; Zeng, Zhihong ; Gittens, William ; Rey, Stephanie A. ; Staras, Kevin ; Mancini, Grazia M. S. ; McKinnon, Peter J. ; Wang, Zhao-Qi ; Wagner, Justin D. ; Yoon, Grace ; Caldecott, Keith W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-01, Vol.541 (7635), p.87-91
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TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ
Author / Creator:Papageorgiou, Ismini E. ; Lewen, Andrea ; Galow, Lukas V. ; Cesetti, Tiziana ; Scheffel, Jörg ; Regen, Tommy ; Hanisch, Uwe-Karsten ; Kann, Oliver
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (1), p.212-217
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Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner
Author / Creator:Vasistha, Navneet A. ; Pardo-Navarro, Maria ; Gasthaus, Janina ; Weijers, Dilys ; Müller, Michaela K. ; García-González, Diego ; Malwade, Susmita ; Korshunova, Irina ; Pfisterer, Ulrich ; von Engelhardt, Jakob ; Hougaard, Karin S. ; Khodosevich, Konstantin
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-10, Vol.25 (10), p.2313-2329
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iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function
Author / Creator:Ni, Peiyan ; Noh, Haneul ; Park, Gun-Hoo ; Shao, Zhicheng ; Guan, Youxin ; Park, James M. ; Yu, Sophy ; Park, Joy S. ; Coyle, Joseph T. ; Weinberger, Daniel R. ; Straub, Richard E. ; Cohen, Bruce M. ; McPhie, Donna L. ; Yin, Changhong ; Huang, Weihua ; Kim, Hae-Young ; Chung, Sangmi
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-11, Vol.25 (11), p.2873-2888
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NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
Author / Creator:Zhang, Xiao ; Liu, Yao ; Hong, Xiaoqi ; Li, Xia ; Meshul, Charles K. ; Moore, Cynthia ; Yang, Yabing ; Han, Yanfei ; Li, Wei-Guang ; Qi, Xin ; Lou, Huifang ; Duan, Shumin ; Xu, Tian-Le ; Tong, Xiaoping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5740-18, Article 5740
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Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons
Author / Creator:Allodi, Ilary ; Montañana-Rosell, Roser ; Selvan, Raghavendra ; Löw, Peter ; Kiehn, Ole
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3251-3251, Article 3251
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Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1
Author / Creator:Stachowiak, E. K. ; Benson, C. A. ; Narla, S. T. ; Dimitri, A. ; Chuye, L. E. Bayona ; Dhiman, S. ; Harikrishnan, K. ; Elahi, S. ; Freedman, D. ; Brennand, K. J. ; Sarder, P. ; Stachowiak, M. K.
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2017-11, Vol.7 (11), p.6-24, Article 6
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Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS
Author / Creator:Bravo-Hernandez, Mariana ; Tadokoro, Takahiro ; Navarro, Michael R. ; Platoshyn, Oleksandr ; Kobayashi, Yoshiomi ; Marsala, Silvia ; Miyanohara, Atsushi ; Juhas, Stefan ; Juhasova, Jana ; Skalnikova, Helena ; Tomori, Zoltan ; Vanicky, Ivo ; Studenovska, Hana ; Proks, Vladimir ; Chen, PeiXi ; Govea-Perez, Noe ; Ditsworth, Dara ; Ciacci, Joseph D. ; Gao, Shang ; Zhu, Wenlian ; Ahrens, Eric T. ; Driscoll, Shawn P. ; Glenn, Thomas D. ; McAlonis-Downes, Melissa ; Da Cruz, Sandrine ; Pfaff, Samuel L. ; Kaspar, Brian K. ; Cleveland, Don W. ; Marsala, Martin
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-01, Vol.26 (1), p.118-130
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GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury
Author / Creator:Zonouzi, Marzieh ; Scafidi, Joseph ; Li, Peijun ; McEllin, Brian ; Edwards, Jorge ; Dupree, Jeffrey L ; Harvey, Lloyd ; Sun, Dandan ; Hübner, Christian A ; Cull-Candy, Stuart G ; Farrant, Mark ; Gallo, Vittorio
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2015-05, Vol.18 (5), p.674-682
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Prefrontal parvalbumin cells are sensitive to stress and mediate anxiety-related behaviors in female mice
Author / Creator:Page, Chloe E. ; Shepard, Ryan ; Heslin, Kelsey ; Coutellier, Laurence
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-12, Vol.9 (1), p.19772-9, Article 19772
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Medial ganglionic eminence–like cells derived from human embryonic stem cells correct learning and memory deficits
Author / Creator:Liu, Yan ; Weick, Jason P ; Liu, Huisheng ; Krencik, Robert ; Zhang, Xiaoqing ; Ma, Lixiang ; Zhou, Guo-min ; Ayala, Melvin ; Zhang, Su-Chun
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2013-05, Vol.31 (5), p.440-447
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Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure
Author / Creator:de Salas-Quiroga, Adán ; García-Rincón, Daniel ; Gómez-Domínguez, Daniel ; Valero, Manuel ; Simón-Sánchez, Samuel ; Paraíso-Luna, Juan ; Aguareles, José ; Pujadas, Mitona ; Muguruza, Carolina ; Callado, Luis F. ; Lutz, Beat ; Guzmán, Manuel ; de la Prida, Liset Menéndez ; Galve-Roperh, Ismael
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2020-04, Vol.45 (5), p.877-886
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Showing 1 to 20 of 198 results

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Network abnormalities and interneuron dysfunction in Alzheimer disease

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Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders

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Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell–derived cortical interneurons from subjects with schizophrenia

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Assembly of functionally integrated human forebrain spheroids

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Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment

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Interneuron dysfunction in psychiatric disorders

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Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

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Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder

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XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

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TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ

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Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner

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iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function

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NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety

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Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

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Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1

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Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS

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GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury

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Prefrontal parvalbumin cells are sensitive to stress and mediate anxiety-related behaviors in female mice

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Medial ganglionic eminence–like cells derived from human embryonic stem cells correct learning and memory deficits

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Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure

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