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Newsletter articlesFull Text
INTERNATIONAL PATENT: DANA-FARBER CANCER INSTITUTE, INC. , HATCHER, JOHN M. , GRAY, NATHANAEL S. , JIANG, BAISHAN , ZHANG, TINGHU , CHE, JIANWEI , GAO, YANG , JONES, LYN HOWARD FILES APPLICATION FOR "...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy
Author / Creator:Xiong, Wenjun ; Gao, Xueliang ; Zhang, Tiantian ; Jiang, Baishan ; Hu, Ming-Ming ; Bu, Xia ; Gao, Yang ; Zhang, Lin-Zhou ; Xiao, Bo-Lin ; He, Chuan ; Sun, Yishuang ; Li, Haiou ; Shi, Jie ; Xiao, Xiangling ; Xiang, Bolin ; Xie, Conghua ; Chen, Gang ; Zhang, Haojian ; Wei, Wenyi ; Freeman, Gordon J. ; Shu, Hong-Bing ; Wang, Haizhen ; Zhang, Jinfang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1700-1700, Article 1700
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ArticlesPeer ReviewedFull Text
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
Author / Creator:Olson, Calla M ; Jiang, Baishan ; Erb, Michael A ; Liang, Yanke ; Doctor, Zainab M ; Zhang, Zinan ; Zhang, Tinghu ; Kwiatkowski, Nicholas ; Boukhali, Myriam ; Green, Jennifer L ; Haas, Wilhelm ; Nomanbhoy, Tyzoon ; Fischer, Eric S ; Young, Richard A ; Bradner, James E ; Winter, Georg E ; Gray, Nathanael S
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2018-02, Vol.14 (2), p.163-170
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ArticlesPeer ReviewedFull Text
Discovery and resistance mechanism of a selective CDK12 degrader
Author / Creator:Jiang, Baishan ; Gao, Yang ; Che, Jianwei ; Lu, Wenchao ; Kaltheuner, Ines H. ; Dries, Ruben ; Kalocsay, Marian ; Berberich, Matthew J. ; Jiang, Jie ; You, Inchul ; Kwiatkowski, Nicholas ; Riching, Kristin M. ; Daniels, Danette L. ; Sorger, Peter K. ; Geyer, Matthias ; Zhang, Tinghu ; Gray, Nathanael S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2021-06, Vol.17 (6), p.675-683
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ArticlesPeer ReviewedFull Text
MELK is not necessary for the proliferation of basal-like breast cancer cells
Author / Creator:Huang, Hai-Tsang ; Seo, Hyuk-Soo ; Zhang, Tinghu ; Wang, Yubao ; Jiang, Baishan ; Li, Qing ; Buckley, Dennis L ; Nabet, Behnam ; Roberts, Justin M ; Paulk, Joshiawa ; Dastjerdi, Shiva ; Winter, Georg E ; McLauchlan, Hilary ; Moran, Jennifer ; Bradner, James E ; Eck, Michael J ; Dhe-Paganon, Sirano ; Zhao, Jean J ; Gray, Nathanael S
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2017-09, Vol.6 (9, 2017)
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ArticlesPeer ReviewedFull Text
Palmitoylation of KSHV pORF55 is required for Golgi localization and efficient progeny virion production
Author / Creator:Zhou, Yaru ; Tian, Xuezhang ; Wang, Shaowei ; Gao, Ming ; Zhang, Chuchu ; Ma, Jiali ; Cheng, Xi ; Bai, Lei ; Qin, Hai-Bin ; Luo, Min-Hua ; Qin, Qingsong ; Jiang, Baishan ; Lan, Ke ; Zhang, Junjie
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-04, Vol.20 (4), p.e1012141-e1012141
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ArticlesPeer ReviewedFull Text
Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
Author / Creator:Ye, Minhui ; Fang, Yingzhe ; Chen, Lu ; Song, Zemin ; Bao, Qing ; Wang, Fei ; Huang, Hao ; Xu, Jin ; Wang, Ziwen ; Xiao, Ruijing ; Han, Meng ; Gao, Song ; Liu, Hudan ; Jiang, Baishan ; Qing, Guoliang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-03, Vol.15 (1), p.2377-2377, Article 2377
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ArticlesPeer ReviewedFull Text
Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells
Author / Creator:Hu, Zheng ; Shi, Zhaoying ; Guo, Xiaogang ; Jiang, Baishan ; Wang, Guo ; Luo, Dixian ; Chen, Yonglong ; Zhu, Yuan-Shan
Publisher:England: BioMed Central Ltd
Journal title:Cell & bioscience, 2018-02, Vol.8 (1), p.12-12, Article 12
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ArticlesPeer ReviewedFull Text
Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis
Author / Creator:Nie, Tao ; Hui, Xiaoyan ; Mao, Liufeng ; Nie, Baoming ; Li, Kuai ; Sun, Wei ; Gao, Xuefei ; Tang, Xiaofeng ; Xu, Yong ; Jiang, Baishan ; Tu, Zhengcao ; Li, Peng ; Ding, Ke ; Han, Weiping ; Zhang, Shaoping ; Xu, Aimin ; Ding, Sheng ; Liu, Pentao ; Patterson, Adam ; Cooper, Garth ; Wu, Donghai
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-11, Vol.6 (1), p.36382-36382, Article 36382
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ArticlesPeer ReviewedFull Text
PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies
Author / Creator:Kumarasamy, Vishnu ; Gao, Zhe ; Zhao, Bosheng ; Jiang, Baishan ; Rubin, Seth M. ; Burgess, Kevin ; Witkiewicz, Agnieszka K. ; Knudsen, Erik S.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2023-10, Vol.129 (8), p.1238-1250
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ArticlesPeer ReviewedFull Text
Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia
Author / Creator:Gao, Xueliang ; Qin, Shenghui ; Wu, Yongxia ; Chu, Chen ; Jiang, Baishan ; Johnson, Roger H ; Kuang, Dong ; Zhang, Jie ; Wang, Xi ; Mehta, Anand ; Tew, Kenneth D ; Leone, Gustavo W ; Yu, Xue-Zhong ; Wang, Haizhen
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-08, Vol.131 (16), p.1-16
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ArticlesPeer ReviewedFull Text
pH-dependent and cathepsin B activable CaCO3 nanoprobe for targeted in vivo tumor imaging
Author / Creator:Sun, Ning ; Wang, Dou ; Yao, Guoqiang ; Li, Xiaomei ; Mei, Ting ; Zhou, Xinke ; Wong, Kwok-Yin ; Jiang, Baishan ; Fang, Zhiyuan
Publisher:Dove
Journal title:International journal of nanomedicine, 2019-01, Vol.14, p.4309-4317
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ArticlesPeer ReviewedFull Text
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells
Author / Creator:Johannessen, Liv ; Sundberg, Thomas B ; O'Connell, Daniel J ; Kolde, Raivo ; Berstler, James ; Billings, Katelyn J ; Khor, Bernard ; Seashore-Ludlow, Brinton ; Fassl, Anne ; Russell, Caitlin N ; Latorre, Isabel J ; Jiang, Baishan ; Graham, Daniel B ; Perez, Jose R ; Sicinski, Piotr ; Phillips, Andrew J ; Schreiber, Stuart L ; Gray, Nathanael S ; Shamji, Alykhan F ; Xavier, Ramnik J
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-10, Vol.13 (10), p.1102-1108
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ArticlesPeer ReviewedFull Text
pH-dependent and cathepsin B activable CaC[O.sub.3] nanoprobe for targeted in vivo tumor imaging
Author / Creator:Sun, Ning ; Wang, Dou ; Yao, Guoqiang ; Li, Xiaomei ; Mei, Ting ; Zhou, Xinke ; Wong, Kwok-Yin ; Jiang, Baishan ; Fang, Zhiyuan
Publisher:Dove Medical Press Limited
Journal title:International journal of nanomedicine, 2019-06, p.4309
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ArticlesPeer ReviewedFull Text
pH-dependent and cathepsin B activable CaCO 3 nanoprobe for targeted in vivo tumor imaging
Author / Creator:Sun, Ning ; Wang, Dou ; Yao, Guoqiang ; Li, Xiaomei ; Mei, Ting ; Zhou, Xinke ; Wong, Kwok-Yin ; Jiang, Baishan ; Fang, Zhiyuan
Publisher:New Zealand
Journal title:International journal of nanomedicine, 2019-06, Vol.14, p.4309-4317
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ArticlesPeer ReviewedFull Text
β-decay studies approaching the N=20 island of inversion with a new shell-model Hamiltonian
Author / Creator:Jiang, WeiGuang ; Hu, BaiShan ; Xu, FuRong ; Han, Rui ; Hua, Hui
Publisher:Beijing: Science China Press
Journal title:Science China. Physics, mechanics & astronomy, 2017-08, Vol.60 (8), p.15-20, Article 082011
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ReportsFull Text
Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia
Author / Creator:Gao, Xueliang ; Qin, Shenghui ; Wu, Yongxia ; Chu, Chen ; Jiang, Baishan ; Johnson, Roger H ; Kuang, Dong ; Zhang, Jie ; Wang, Xi ; Mehta, Anand ; Tew, Kenneth D ; Leone, Gustavo W ; Yu, Xue-Zhong ; Wang, Haizhen
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2021, Vol.131 (16)
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ReportsFull Text
Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia
Author / Creator:Gao, Xueliang ; Qin, Shenghui ; Wu, Yongxia ; Chu, Chen ; Jiang, Baishan ; Johnson, Roger H ; Kuang, Dong ; Zhang, Jie ; Wang, Xi ; Mehta, Anand ; Tew, Kenneth D ; Leone, Gustavo W ; Yu, Xue-Zhong ; Wang, Haizhen
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2021, Vol.131 (16)
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ReportsFull Text
Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells
Author / Creator:Hu, Zheng ; Shi, Zhaoying ; Guo, Xiaogang ; Jiang, Baishan ; Wang, Guo ; Luo, Dixian ; Chen, Yonglong ; Zhu, Yuan-Shan
Publisher:BioMed Central Ltd
Journal title:Cell & Bioscience, 2018, Vol.8 (1)
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ArticlesFull Text
Targeting the PI5P4K lipid kinase family in cancer using novel covalent inhibitors
Author / Creator:Sindhu Carmen Sivakumaren ; Shim, Hyeseok ; Zhang, Tinghu ; Ferguson, Fleur M ; Lundquist, Mark R ; Browne, Christopher M ; Hyuk-Soo Seo ; Paddock, Marcia N ; Manz, Theresa D ; Jiang, Baishan ; Ming-Feng, Hao ; Krishnan, Pranav ; Wang, Diana G ; Yang, T Jonathan ; Kwiatkowski, Nicholas P ; Ficarro, Scott B ; Cunningham, James M ; Marto, Jarrod A ; Dhe-Paganon, Sirano ; Cantley, Lewis C ; Gray, Nathanael S
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-10
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INTERNATIONAL PATENT: DANA-FARBER CANCER INSTITUTE, INC. , HATCHER, JOHN M. , GRAY, NATHANAEL S. , JIANG, BAISHAN , ZHANG, TINGHU , CHE, JIANWEI , GAO, YANG , JONES, LYN HOWARD FILES APPLICATION FOR "...

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USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

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Discovery and resistance mechanism of a selective CDK12 degrader

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MELK is not necessary for the proliferation of basal-like breast cancer cells

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Palmitoylation of KSHV pORF55 is required for Golgi localization and efficient progeny virion production

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Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

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Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells

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Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis

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PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies

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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia

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pH-dependent and cathepsin B activable CaCO3 nanoprobe for targeted in vivo tumor imaging

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Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells

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pH-dependent and cathepsin B activable CaC[O.sub.3] nanoprobe for targeted in vivo tumor imaging

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pH-dependent and cathepsin B activable CaCO 3 nanoprobe for targeted in vivo tumor imaging

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β-decay studies approaching the N=20 island of inversion with a new shell-model Hamiltonian

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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia

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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia

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Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells

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Targeting the PI5P4K lipid kinase family in cancer using novel covalent inhibitors

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