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ArticlesPeer ReviewedFull Text
Joint single-cell measurements of nuclear proteins and RNA in vivo
Author / Creator:Chung, Hattie ; Parkhurst, Christopher N. ; Magee, Emma M. ; Phillips, Devan ; Habibi, Ehsan ; Chen, Fei ; Yeung, Bertrand Z. ; Waldman, Julia ; Artis, David ; Regev, Aviv
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2021-10, Vol.18 (10), p.1204-1212
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Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
Author / Creator:Abiega, Oihane ; Beccari, Sol ; Diaz-Aparicio, Irune ; Nadjar, Agnes ; Layé, Sophie ; Leyrolle, Quentin ; Gómez-Nicola, Diego ; Domercq, María ; Pérez-Samartín, Alberto ; Sánchez-Zafra, Víctor ; Paris, Iñaki ; Valero, Jorge ; Savage, Julie C. ; Hui, Chin-Wai ; Tremblay, Marie-Ève ; Deudero, Juan J. P. ; Brewster, Amy L. ; Anderson, Anne E. ; Zaldumbide, Laura ; Galbarriatu, Lara ; Marinas, Ainhoa ; Vivanco, Maria dM ; Matute, Carlos ; Maletic-Savatic, Mirjana ; Encinas, Juan M. ; Sierra, Amanda
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2016-05, Vol.14 (5), p.e1002466-48
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Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
Author / Creator:Jimenez-Mateos, Eva M ; Engel, Tobias ; Merino-Serrais, Paula ; McKiernan, Ross C ; Tanaka, Katsuhiro ; Mouri, Genshin ; Sano, Takanori ; O'Tuathaigh, Colm ; Waddington, John L ; Prenter, Suzanne ; Delanty, Norman ; Farrell, Michael A ; O'Brien, Donncha F ; Conroy, Ronán M ; Stallings, Raymond L ; DeFelipe, Javier ; Henshall, David C
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-07, Vol.18 (7), p.1087-1094
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Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy
Author / Creator:Liu, Chong ; Zhao, Xue-Min ; Wang, Qiao ; Du, Ting-Ting ; Zhang, Mo-Xuan ; Wang, Hui-Zhi ; Li, Ren-Peng ; Liang, Kun ; Gao, Yuan ; Zhou, Si-Yu ; Xue, Tao ; Zhang, Jian-Guo ; Han, Chun-Lei ; Shi, Lin ; Zhang, Liang-Wen ; Meng, Fan-Gang
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2023-07, Vol.20 (1), p.161-161, Article 161
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Algal toxin impairs sea lion memory and hippocampal connectivity, with implications for strandings
Author / Creator:Cook, Peter F. ; Reichmuth, Colleen ; Rouse, Andrew A. ; Libby, Laura A. ; Dennison, Sophie E. ; Carmichael, Owen T. ; Kruse-Elliott, Kris T. ; Bloom, Josh ; Singh, Baljeet ; Fravel, Vanessa A. ; Barbosa, Lorraine ; Stuppino, Jim J. ; Van Bonn, William G. ; Gulland, Frances M. D. ; Ranganath, Charan
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-12, Vol.350 (6267), p.1545-1547
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Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis
Author / Creator:Dong, Xinyan ; Fan, Jianchen ; Lin, Donghui ; Wang, Xuehui ; Kuang, Haoyu ; Gong, Lifen ; Chen, Chen ; Jiang, Jie ; Xia, Ningxiao ; He, Dahong ; Shen, Weida ; Jiang, Peifang ; Kuang, Rong ; Zeng, Linghui ; Xie, Yicheng
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2022-09, Vol.19 (1), p.226-22, Article 226
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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain
Author / Creator:Gehman, Lauren T ; Stoilov, Peter ; Maguire, Jamie ; Damianov, Andrey ; Lin, Chia-Ho ; Shiue, Lily ; Ares, Manuel ; Mody, Istvan ; Black, Douglas L
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-07, Vol.43 (7), p.706-711
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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in...
Author / Creator:Papazian, Irini ; Tsoukala, Eleni ; Boutou, Athena ; Karamita, Maria ; Kambas, Konstantinos ; Iliopoulou, Lida ; Fischer, Roman ; Kontermann, Roland E. ; Denis, Maria C. ; Kollias, George ; Lassmann, Hans ; Probert, Lesley
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2021-09, Vol.18 (1), p.222-222, Article 222
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Pulsed-Focused Ultrasound Provides Long-Term Suppression of Epileptiform Bursts in the Kainic Acid-Induced Epilepsy Rat Model
Author / Creator:Chu, Po-Chun ; Yu, Hsiang-Yu ; Lee, Cheng-Chia ; Fisher, Robert ; Liu, Hao-Li
Publisher:Cham: Springer International Publishing
Journal title:Neurotherapeutics, 2022-07, Vol.19 (4), p.1368-1380
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Basic Science and Pathogenesis
Author / Creator:Buchanan, Rebecca A ; Harrison, Fiona E
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e093434
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Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice
Author / Creator:Maroso, Mattia ; Balosso, Silvia ; Ravizza, Teresa ; Iori, Valentina ; Wright, Christopher Ian ; French, Jacqueline ; Vezzani, Annamaria
Publisher:New York: Springer-Verlag
Journal title:Neurotherapeutics, 2011-04, Vol.8 (2), p.304-315
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Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model
Author / Creator:Desloovere, Jana ; Boon, Paul ; Larsen, Lars Emil ; Goossens, Marie-Gabrielle ; Delbeke, Jean ; Carrette, Evelien ; Wadman, Wytse ; Vonck, Kristl ; Raedt, Robrecht
Publisher:Cham: Springer International Publishing
Journal title:Neurotherapeutics, 2022-01, Vol.19 (1), p.342-351
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Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates
Author / Creator:Petroff, Rebekah L. ; Williams, Christopher ; Li, Jian-Liang ; MacDonald, James W. ; Bammler, Theo K. ; Richards, Todd ; English, Christopher N. ; Baldessari, Audrey ; Shum, Sara ; Jing, Jing ; Isoherranen, Nina ; Crouthamel, Brenda ; McKain, Noelle ; Grant, Kimberly S. ; Burbacher, Thomas M. ; Harry, G. Jean
Publisher:United States: National Institute of Environmental Health Sciences
Journal title:Environmental health perspectives, 2022-09, Vol.130 (9), p.97003-19
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Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity
Author / Creator:Landucci, Elisa ; Mazzantini, Costanza ; Buonvicino, Daniela ; Pellegrini-Giampietro, Domenico E. ; Bergonzi, Maria Camilla
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-03, Vol.26 (6), p.1592
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Compound 4f, a novel brain-penetrant reversible monoacylglycerol inhibitor, ameliorates neuroinflammation, neuronal cell loss, and cognitive impairment in mice with kainic acid-induced neurodegenerati...
Author / Creator:Arimura, Naoto ; Maeda, Chie ; Aoyama, Kazunobu ; Yamaguchi, Namiko ; Sugiura, Ayumu ; Takahashi, Yasuko ; Maeda, Ryouta ; Ando, Tatsuya ; Kamata, Makoto ; Matsui, Hideki ; Tanaka, Maiko
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-11, Vol.19 (11), p.e0312090
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Protection by Nano-Encapsulated Bacoside A and Bacopaside I in Seizure Alleviation and Improvement in Sleep- In Vitro and In Vivo Evidences
Author / Creator:C. Sekhar, Vini ; Gulia, Kamalesh K. ; Deepti, Ayswaria ; Chakrapani, P. S. Baby ; Baby, Sabulal ; Viswanathan, Gayathri
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2024-06, Vol.61 (6), p.3296-3313
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Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus
Author / Creator:Ho, Ying-Hao ; Lin, Yu-Te ; Wu, Chih-Wei J. ; Chao, Yung-Mei ; Chang, Alice Y. W. ; Chan, Julie Y. H.
Publisher:England: BioMed Central Ltd
Journal title:Journal of biomedical science, 2015-06, Vol.22 (1), p.46, Article 46
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Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model
Author / Creator:Panlilio, Jennifer M. ; Aluru, Neelakanteswar ; Hahn, Mark E.
Publisher:United States: National Institute of Environmental Health Sciences
Journal title:Environmental health perspectives, 2020-11, Vol.128 (11), p.117002
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The Glycolysis Inhibitor 2-Deoxy-d-Glucose Exerts Different Neuronal Effects at Circuit and Cellular Levels, Partially Reverses Behavioral Alterations and does not Prevent NADPH Diaphorase Activity Re...
Author / Creator:Khatibi, Vahid Ahli ; Rahdar, Mona ; Rezaei, Mahmoud ; Davoudi, Shima ; Nazari, Milad ; Mohammadi, Mohammad ; Raoufy, Mohammad Reza ; Mirnajafi-Zadeh, Javad ; Hosseinmardi, Narges ; Behzadi, Gila ; Janahmadi, Mahyar
Publisher:New York: Springer US
Journal title:Neurochemical research, 2023-01, Vol.48 (1), p.210-228
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Dangerous Relations in the Arctic Marine Food Web: Interactions between Toxin Producing Pseudo-nitzschia Diatoms and Calanus Copepodites
Author / Creator:Harðardóttir, Sara ; Pančić, Marina ; Tammilehto, Anna ; Krock, Bernd ; Møller, Eva ; Nielsen, Torkel ; Lundholm, Nina
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2015-06, Vol.13 (6), p.3809-3835
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Joint single-cell measurements of nuclear proteins and RNA in vivo

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Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling

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Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

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Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy

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Algal toxin impairs sea lion memory and hippocampal connectivity, with implications for strandings

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Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis

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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in...

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Pulsed-Focused Ultrasound Provides Long-Term Suppression of Epileptiform Bursts in the Kainic Acid-Induced Epilepsy Rat Model

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Basic Science and Pathogenesis

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Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

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Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model

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Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates

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Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity

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Compound 4f, a novel brain-penetrant reversible monoacylglycerol inhibitor, ameliorates neuroinflammation, neuronal cell loss, and cognitive impairment in mice with kainic acid-induced neurodegenerati...

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Protection by Nano-Encapsulated Bacoside A and Bacopaside I in Seizure Alleviation and Improvement in Sleep- In Vitro and In Vivo Evidences

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Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus

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Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model

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The Glycolysis Inhibitor 2-Deoxy-d-Glucose Exerts Different Neuronal Effects at Circuit and Cellular Levels, Partially Reverses Behavioral Alterations and does not Prevent NADPH Diaphorase Activity Re...

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Dangerous Relations in the Arctic Marine Food Web: Interactions between Toxin Producing Pseudo-nitzschia Diatoms and Calanus Copepodites

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