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ArticlesPeer ReviewedFull Text
Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
Author / Creator:Zaretsky, Jesse M ; Garcia-Diaz, Angel ; Shin, Daniel S ; Escuin-Ordinas, Helena ; Hugo, Willy ; Hu-Lieskovan, Siwen ; Torrejon, Davis Y ; Abril-Rodriguez, Gabriel ; Sandoval, Salemiz ; Barthly, Lucas ; Saco, Justin ; Homet Moreno, Blanca ; Mezzadra, Riccardo ; Chmielowski, Bartosz ; Ruchalski, Kathleen ; Shintaku, I. Peter ; Sanchez, Phillip J ; Puig-Saus, Cristina ; Cherry, Grace ; Seja, Elizabeth ; Kong, Xiangju ; Pang, Jia ; Berent-Maoz, Beata ; Comin-Anduix, Begoña ; Graeber, Thomas G ; Tumeh, Paul C ; Schumacher, Ton N.M ; Lo, Roger S ; Ribas, Antoni
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-09, Vol.375 (9), p.819-829
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RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors
Author / Creator:Su, Fei ; Viros, Amaya ; Milagre, Carla ; Trunzer, Kerstin ; Bollag, Gideon ; Spleiss, Olivia ; Reis-Filho, Jorge S ; Kong, Xiangju ; Koya, Richard C ; Flaherty, Keith T ; Chapman, Paul B ; Kim, Min Jung ; Hayward, Robert ; Martin, Matthew ; Yang, Hong ; Wang, Qiongqing ; Hilton, Holly ; Hang, Julie S ; Noe, Johannes ; Lambros, Maryou ; Geyer, Felipe ; Dhomen, Nathalie ; Niculescu-Duvaz, Dan ; Niculescu-Duvaz, Ion ; Zambon, Alfonso ; Preece, Natasha ; Robert, Lídia ; Otte, Nicholas J ; Mok, Stephen ; Kee, Damien ; Ma, Yan ; Zhang, Chao ; Habets, Gaston ; Burton, Elizabeth A ; Wong, Bernice ; Nguyen, Hoa ; Kockx, Mark ; Andries, Luc ; Lestini, Brian ; Nolop, Keith B ; Lee, Richard J ; Joe, Andrew K ; Troy, James L ; Gonzalez, Rene ; Hutson, Thomas E ; Puzanov, Igor ; Chmielowski, Bartosz ; Springer, Caroline J ; McArthur, Grant A ; Sosman, Jeffrey A ; Lo, Roger S ; Ribas, Antoni ; Marais, Richard
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2012-01, Vol.366 (3), p.207-215
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
Author / Creator:Müller, Judith ; Krijgsman, Oscar ; Tsoi, Jennifer ; Robert, Lidia ; Hugo, Willy ; Song, Chunying ; Kong, Xiangju ; Possik, Patricia A. ; Cornelissen-Steijger, Paulien D. M. ; Foppen, Marnix H Geukes ; Kemper, Kristel ; Goding, Colin R. ; McDermott, Ultan ; Blank, Christian ; Haanen, John ; Graeber, Thomas G. ; Ribas, Antoni ; Lo, Roger S. ; Peeper, Daniel S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-12, Vol.5 (1), p.5712-5712, Article 5712
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
Author / Creator:Poulikakos, Poulikos I. ; Persaud, Yogindra ; Janakiraman, Manickam ; Kong, Xiangju ; Ng, Charles ; Moriceau, Gatien ; Shi, Hubing ; Atefi, Mohammad ; Titz, Bjoern ; Gabay, May Tal ; Salton, Maayan ; Dahlman, Kimberly B. ; Tadi, Madhavi ; Wargo, Jennifer A. ; Flaherty, Keith T. ; Kelley, Mark C. ; Misteli, Tom ; Chapman, Paul B. ; Sosman, Jeffrey A. ; Graeber, Thomas G. ; Ribas, Antoni ; Lo, Roger S. ; Rosen, Neal ; Solit, David B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-12, Vol.480 (7377), p.387-390
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Mangiferin Improved Palmitate-Induced-Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPARα: Mangiferin Improved Insulin Resistance
Author / Creator:Li, Ying ; Guan, Hongjun ; Yuan, Hang ; Kong, Xiangju ; Zhang, Qiao ; Niu, Yucun
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of diabetes research, 2019, Vol.2019 (2019), p.1-13
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Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutri...
Author / Creator:Tang, Xuanfeng ; Lv, Xinyi ; Wang, Ruohua ; Li, Xiaoqing ; Xu, Wenyu ; Wang, Nan ; Ma, Shuran ; Huang, He ; Niu, Yucun ; Kong, Xiangju
Publisher:London: BioMed Central Ltd
Journal title:Nutrition journal, 2023-10, Vol.22 (1), p.1-48, Article 48
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
Author / Creator:Nazarian, Ramin ; Shi, Hubing ; Wang, Qi ; Kong, Xiangju ; Koya, Richard C. ; Lee, Hane ; Chen, Zugen ; Lee, Mi-Kyung ; Attar, Narsis ; Sazegar, Hooman ; Chodon, Thinle ; Nelson, Stanley F. ; McArthur, Grant ; Sosman, Jeffrey A. ; Ribas, Antoni ; Lo, Roger S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-12, Vol.468 (7326), p.973-977
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Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors
Author / Creator:Marusiak, Anna A. ; Edwards, Zoe C. ; Hugo, Willy ; Trotter, Eleanor W. ; Girotti, Maria R. ; Stephenson, Natalie L. ; Kong, Xiangju ; Gartside, Michael G. ; Fawdar, Shameem ; Hudson, Andrew ; Breitwieser, Wolfgang ; Hayward, Nicholas K. ; Marais, Richard ; Lo, Roger S. ; Brognard, John
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-05, Vol.5 (1), p.3901, Article 3901
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ArticlesPeer ReviewedFull Text
JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma
Author / Creator:Titz, Bjoern ; Lomova, Anastasia ; Le, Allison ; Hugo, Willy ; Kong, Xiangju ; ten Hoeve, Johanna ; Friedman, Michael ; Shi, Hubing ; Moriceau, Gatien ; Song, Chunying ; Hong, Aayoung ; Atefi, Mohammad ; Li, Richard ; Komisopoulou, Evangelia ; Ribas, Antoni ; Lo, Roger S ; Graeber, Thomas G
Publisher:London: Nature Publishing Group UK
Journal title:Cell discovery, 2016-09, Vol.2 (1), p.16028-16028, Article 16028
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Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance
Author / Creator:Shi, Hubing ; Moriceau, Gatien ; Kong, Xiangju ; Lee, Mi-Kyung ; Lee, Hane ; Koya, Richard C ; Ng, Charles ; Chodon, Thinle ; Scolyer, Richard A ; Dahlman, Kimberly B ; Sosman, Jeffrey A ; Kefford, Richard F ; Long, Georgina V ; Nelson, Stanley F ; Ribas, Antoni ; Lo, Roger S
Publisher:England
Journal title:Nature communications, 2012-03, Vol.3, p.724
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Therapy-induced tumour secretomes promote resistance and tumour progression
Author / Creator:Obenauf, Anna C. ; Zou, Yilong ; Ji, Andrew L. ; Vanharanta, Sakari ; Shu, Weiping ; Shi, Hubing ; Kong, Xiangju ; Bosenberg, Marcus C. ; Wiesner, Thomas ; Rosen, Neal ; Lo, Roger S. ; Massagué, Joan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-04, Vol.520 (7547), p.368-372
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Design and application of graphite film with high thermal conductivity in SAR antenna
Author / Creator:Zhu, Shangkun ; Shang, Xiuyu ; Xu, Jiyuan ; Kong, Xiangju ; Qian, Jiyu ; Wei, Tao
Publisher:Bristol: IOP Publishing
Journal title:Journal of physics. Conference series, 2024-11, Vol.2882 (1), p.12001
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Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
Author / Creator:Shi, Hubing ; Moriceau, Gatien ; Kong, Xiangju ; Lee, Mi-Kyung ; Lee, Hane ; Koya, Richard C. ; Ng, Charles ; Chodon, Thinle ; Scolyer, Richard A. ; Dahlman, Kimberly B. ; Sosman, Jeffrey A. ; Kefford, Richard F. ; Long, Georgina V. ; Nelson, Stanley F. ; Ribas, Antoni ; Lo, Roger S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012-03, Vol.3 (1), p.724-724, Article 724
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Causal associations of histidine and 12 site-specific cancers: a bidirectional Mendelian randomization study
Author / Creator:Kong, Xiangju ; Yu, Jiaying ; Zhu, Zhuolin ; Wang, Cheng ; Zhang, Runan ; Qi, Jiayue ; Wang, Yiran ; Wang, Xiaoxin ; Pan, Sijia ; Liu, Liyan ; Feng, Rennan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Molecular genetics and genomics : MGG, 2023-11, Vol.298 (6), p.1331-1341
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RAF inhibitor resistance ismediated by dimerization of aberrantly spliced BRAF(V600E)
Author / Creator:Poulikakos, Poulikos I ; Persaud, Yogindra ; Janakiraman, Manickam ; Kong, Xiangju ; Ng, Charles ; Moriceau, Gatien ; Shi, Hubing ; Atefi, Mohammad ; Titz, Bjoern ; Gabay, May Tal ; Salton, Maayan ; Dahlman, Kimberly B ; Tadi, Madhavi ; Wargo, Jennifer A ; Flaherty, Keith T ; Kelley, Mark C ; Misteli, Tom ; Chapman, Paul B ; Sosman, Jeffrey A ; Graeber, Thomas G ; Ribas, Antoni ; Lo, Roger S ; Rosen, Neal ; Solit, David B
Publisher:London: Nature Publishing Group
Journal title:Nature (London), 2011-12, Vol.480 (7377), p.387
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ReportsFull Text
Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutri...
Author / Creator:Tang, Xuanfeng ; Lv, Xinyi ; Wang, Ruohua ; Li, Xiaoqing ; Xu, Wenyu ; Wang, Nan ; Ma, Shuran ; Huang, He ; Niu, Yucun ; Kong, Xiangju
Publisher:BioMed Central Ltd
Journal title:Nutrition Journal, 2023, Vol.22 (1)
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ReportsFull Text
Therapy-induced tumour secretomes promote resistance and tumour progression
Author / Creator:Obenauf, Anna C ; Zou, Yilong ; Ji, Andrew L ; Vanharanta, Sakari ; Shu, Weiping ; Shi, Hubing ; Kong, Xiangju ; Bosenberg, Marcus C ; Wiesner, Thomas ; Rosen, Neal ; Lo, Roger S ; Massague, Joan
Publisher:Nature Publishing Group
Journal title:Nature, 2015, p.368
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ReportsFull Text
Therapy-induced tumour secretomes promote resistance and tumour progression
Author / Creator:Obenauf, Anna C ; Zou, Yilong ; Ji, Andrew L ; Vanharanta, Sakari ; Shu, Weiping ; Shi, Hubing ; Kong, Xiangju ; Bosenberg, Marcus C ; Wiesner, Thomas ; Rosen, Neal ; Lo, Roger S ; Massague, Joan
Publisher:Nature Publishing Group
Journal title:Nature, 2015, p.368
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ReportsFull Text
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF
Author / Creator:Poulikakos, Poulikos I ; Persaud, Yogindra ; Janakiraman, Manickam ; Kong, Xiangju ; Ng, Charles ; Moriceau, Gatien ; Shi, Hubing
Publisher:Nature Publishing Group
Journal title:Nature, 2011, Vol.480 (7377), p.387
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ReportsFull Text
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF
Author / Creator:Poulikakos, Poulikos I ; Persaud, Yogindra ; Janakiraman, Manickam ; Kong, Xiangju ; Ng, Charles ; Moriceau, Gatien ; Shi, Hubing
Publisher:Nature Publishing Group
Journal title:Nature, 2011, Vol.480 (7377), p.387
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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

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RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

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Mangiferin Improved Palmitate-Induced-Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPARα: Mangiferin Improved Insulin Resistance

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Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutri...

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

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Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

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JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma

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Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

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Therapy-induced tumour secretomes promote resistance and tumour progression

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Design and application of graphite film with high thermal conductivity in SAR antenna

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Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance

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Causal associations of histidine and 12 site-specific cancers: a bidirectional Mendelian randomization study

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RAF inhibitor resistance ismediated by dimerization of aberrantly spliced BRAF(V600E)

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Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutri...

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Therapy-induced tumour secretomes promote resistance and tumour progression

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Therapy-induced tumour secretomes promote resistance and tumour progression

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF

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