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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
Author / Creator:Guelen, Lars ; Pagie, Ludo ; Brasset, Emilie ; Meuleman, Wouter ; Faza, Marius B. ; Talhout, Wendy ; Eussen, Bert H. ; de Klein, Annelies ; Wessels, Lodewyk ; de Laat, Wouter ; van Steensel, Bas
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2008-06, Vol.453 (7197), p.948-951
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Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients
Author / Creator:Castelijns, Bas ; Baak, Mirna L. ; Timpanaro, Ilia S. ; Wiggers, Caroline R. M. ; Vermunt, Marit W. ; Shang, Peng ; Kondova, Ivanela ; Geeven, Geert ; Bianchi, Valerio ; de Laat, Wouter ; Geijsen, Niels ; Creyghton, Menno P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.301-301, Article 301
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Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures
Author / Creator:Wang, Xinchen ; Tucker, Nathan R ; Rizki, Gizem ; Mills, Robert ; Krijger, Peter HL ; de Wit, Elzo ; Subramanian, Vidya ; Bartell, Eric ; Nguyen, Xinh-Xinh ; Ye, Jiangchuan ; Leyton-Mange, Jordan ; Dolmatova, Elena V ; van der Harst, Pim ; de Laat, Wouter ; Ellinor, Patrick T ; Newton-Cheh, Christopher ; Milan, David J ; Kellis, Manolis ; Boyer, Laurie A
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-05, Vol.5
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An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo
Author / Creator:Man, Joyce C. K. ; Mohan, Rajiv A. ; Boogaard, Malou van den ; Hilvering, Catharina R. E. ; Jenkins, Catherine ; Wakker, Vincent ; Bianchi, Valerio ; Laat, Wouter de ; Barnett, Phil ; Boukens, Bastiaan J. ; Christoffels, Vincent M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4943-15, Article 4943
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Spatial organization of gene expression: the active chromatin hub
Author / Creator:de Laat, Wouter ; Grosveld, Frank
Publisher:Netherlands: Springer Nature B.V
Journal title:Chromosome research, 2003-01, Vol.11 (5), p.447-459
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Regulation of disease-associated gene expression in the 3D genome
Author / Creator:Krijger, Peter Hugo Lodewijk ; de Laat, Wouter
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2016-12, Vol.17 (12), p.771-782
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Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm
Author / Creator:Yang, Xinan H ; Nadadur, Rangarajan D ; Hilvering, Catharina RE ; Bianchi, Valerio ; Werner, Michael ; Mazurek, Stefan R ; Gadek, Margaret ; Shen, Kaitlyn M ; Goldman, Joseph Aaron ; Tyan, Leonid ; Bekeny, Jenna ; Hall, Johnathon M ; Lee, Nutishia ; Perez-Cervantes, Carlos ; Burnicka-Turek, Ozanna ; Poss, Kenneth D ; Weber, Christopher R ; de Laat, Wouter ; Ruthenburg, Alexander J ; Moskowitz, Ivan P
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-12, Vol.6
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An evaluation of 3C-based methods to capture DNA interactions
Author / Creator:Simonis, Marieke ; Kooren, Jurgen ; de Laat, Wouter
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2007-11, Vol.4 (11), p.895-901
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Getting the genome in shape: the formation of loops, domains and compartments
Author / Creator:Bouwman, Britta AM ; de Laat, Wouter
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2015-08, Vol.16 (1), p.154-154, Article 154
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The complex transcription regulatory landscape of our genome: control in three dimensions
Author / Creator:Splinter, Erik ; de Laat, Wouter
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2011-11, Vol.30 (21), p.4345-4355
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Enhancer hubs and loop collisions identified from single-allele topologies
Author / Creator:Allahyar, Amin ; Vermeulen, Carlo ; Bouwman, Britta A. M. ; Krijger, Peter H. L. ; Verstegen, Marjon J. A. M. ; Geeven, Geert ; van Kranenburg, Melissa ; Pieterse, Mark ; Straver, Roy ; Haarhuis, Judith H. I. ; Jalink, Kees ; Teunissen, Hans ; Renkens, Ivo J. ; Kloosterman, Wigard P. ; Rowland, Benjamin D. ; de Wit, Elzo ; de Ridder, Jeroen ; de Laat, Wouter
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2018-08, Vol.50 (8), p.1151-1160
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Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)
Author / Creator:Simonis, Marieke ; Klous, Petra ; Splinter, Erik ; Moshkin, Yuri ; Willemsen, Rob ; de Wit, Elzo ; van Steensel, Bas ; de Laat, Wouter
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2006-11, Vol.38 (11), p.1348-1354
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DamC reveals principles of chromatin folding in vivo without crosslinking and ligation
Author / Creator:Redolfi, Josef ; Zhan, Yinxiu ; Valdes-Quezada, Christian ; Kryzhanovska, Mariya ; Guerreiro, Isabel ; Iesmantavicius, Vytautas ; Pollex, Tim ; Grand, Ralph S. ; Mulugeta, Eskeatnaf ; Kind, Jop ; Tiana, Guido ; Smallwood, Sebastien A. ; de Laat, Wouter ; Giorgetti, Luca
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2019-06, Vol.26 (6), p.471-480
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Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA
Author / Creator:Léveillé, Nicolas ; Melo, Carlos A. ; Rooijers, Koos ; Díaz-Lagares, Angel ; Melo, Sonia A. ; Korkmaz, Gozde ; Lopes, Rui ; Moqadam, Farhad Akbari ; Maia, Ana R. ; Wijchers, Patrick J. ; Geeven, Geert ; den Boer, Monique L. ; Kalluri, Raghu ; de Laat, Wouter ; Esteller, Manel ; Agami, Reuven
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-03, Vol.6 (1), p.6520-6520, Article 6520
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Epigenomic annotation of gene regulatory alterations during evolution of the primate brain
Author / Creator:Vermunt, Marit W ; Tan, Sander C ; Castelijns, Bas ; Geeven, Geert ; Reinink, Peter ; de Bruijn, Ewart ; Kondova, Ivanela ; Persengiev, Stephan ; Bontrop, Ronald ; Cuppen, Edwin ; de Laat, Wouter ; Creyghton, Menno P
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2016-03, Vol.19 (3), p.494-503
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Robust 4C-seq data analysis to screen for regulatory DNA interactions
Author / Creator:van de Werken, Harmen J G ; Landan, Gilad ; Holwerda, Sjoerd J B ; Hoichman, Michael ; Klous, Petra ; Chachik, Ran ; Splinter, Erik ; Valdes-Quezada, Christian ; Öz, Yuva ; Bouwman, Britta A M ; Verstegen, Marjon J A M ; de Wit, Elzo ; Tanay, Amos ; de Laat, Wouter
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2012-10, Vol.9 (10), p.969-972
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The pluripotent genome in three dimensions is shaped around pluripotency factors
Author / Creator:de Wit, Elzo ; Bouwman, Britta A. M. ; Zhu, Yun ; Klous, Petra ; Splinter, Erik ; Verstegen, Marjon J. A. M. ; Krijger, Peter H. L. ; Festuccia, Nicola ; Nora, Elphège P. ; Welling, Maaike ; Heard, Edith ; Geijsen, Niels ; Poot, Raymond A. ; Chambers, Ian ; de Laat, Wouter
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-09, Vol.501 (7466), p.227-231
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Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
Author / Creator:Hagège, Hélène ; Klous, Petra ; Braem, Caroline ; Splinter, Erik ; Dekker, Job ; Cathala, Guy ; de Laat, Wouter ; Forné, Thierry
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2007-07, Vol.2 (7), p.1722-1733
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Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity
Author / Creator:Fan, Chuannan ; Wang, Qian ; Krijger, Peter H. L. ; Cats, Davy ; Selle, Miriam ; Khorosjutina, Olga ; Dhanjal, Soniya ; Schmierer, Bernhard ; Mei, Hailiang ; de Laat, Wouter ; ten Dijke, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2890-19, Article 2890
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Interactions among Polycomb Domains Are Guided by Chromosome Architecture
Author / Creator:Tolhuis, Bas ; Blom, Marleen ; Kerkhoven, Ron M. ; Pagie, Ludo ; Teunissen, Hans ; Nieuwland, Marja ; Simonis, Marieke ; de Laat, Wouter ; van Lohuizen, Maarten ; van Steensel, Bas
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2011-03, Vol.7 (3), p.e1001343-e1001343
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Showing 1 to 20 of 66 results

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

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Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients

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Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

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An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo

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Spatial organization of gene expression: the active chromatin hub

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Regulation of disease-associated gene expression in the 3D genome

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Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm

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An evaluation of 3C-based methods to capture DNA interactions

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Getting the genome in shape: the formation of loops, domains and compartments

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The complex transcription regulatory landscape of our genome: control in three dimensions

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Enhancer hubs and loop collisions identified from single-allele topologies

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Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

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DamC reveals principles of chromatin folding in vivo without crosslinking and ligation

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Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

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Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

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Robust 4C-seq data analysis to screen for regulatory DNA interactions

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The pluripotent genome in three dimensions is shaped around pluripotency factors

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Quantitative analysis of chromosome conformation capture assays (3C-qPCR)

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Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity

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Interactions among Polycomb Domains Are Guided by Chromosome Architecture

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