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31 results for Lim,+Wei+Wen

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IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues
Author / Creator:Widjaja, Anissa A. ; Chothani, Sonia ; Viswanathan, Sivakumar ; Goh, Joyce Wei Ting ; Lim, Wei-Wen ; Cook, Stuart A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-08, Vol.23 (16), p.8900
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Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
Author / Creator:Lim, Wei-Wen ; Ng, Benjamin ; Widjaja, Anissa ; Xie, Chen ; Su, Liping ; Ko, Nicole ; Lim, Sze-Yun ; Kwek, Xiu-Yi ; Lim, Stella ; Cook, Stuart Alexander ; Schafer, Sebastian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227505
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Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
Author / Creator:Widjaja, Anissa A. ; Viswanathan, Sivakumar ; Shekeran, Shamini G. ; Adami, Eleonora ; Lim, Wei-Wen ; Chothani, Sonia ; Tan, Jessie ; Goh, Joyce Wei Ting ; Chen, Hui Mei ; Lim, Sze Yun ; Boustany-Kari, Carine M. ; Hawkins, Julie ; Petretto, Enrico ; Hübner, Norbert ; Schafer, Sebastian ; Coffman, Thomas M. ; Cook, Stuart A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7497-18, Article 7497
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IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis
Author / Creator:Ng, Benjamin ; Viswanathan, Sivakumar ; Widjaja, Anissa A. ; Lim, Wei-Wen ; Shekeran, Shamini G. ; Goh, Joyce Wei Ting ; Tan, Jessie ; Kuthubudeen, Fathima ; Lim, Sze Yun ; Xie, Chen ; Schafer, Sebastian ; Adami, Eleonora ; Cook, Stuart A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-03, Vol.23 (7), p.3549
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Interleukin-11: A Potential Biomarker and Molecular Therapeutic Target in Non-Small Cell Lung Cancer
Author / Creator:Leung, Jason Hongting ; Ng, Benjamin ; Lim, Wei-Wen
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-07, Vol.11 (14), p.2257
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Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction
Author / Creator:Sweeney, Mark ; O’Fee, Katie ; Villanueva-Hayes, Chelsie ; Rahman, Ekhlas ; Lee, Michael ; Vanezis, Konstantinos ; Andrew, Ivan ; Lim, Wei-Wen ; Widjaja, Anissa ; Barton, Paul J. R. ; Cook, Stuart A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-08, Vol.24 (16), p.12989
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Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload
Author / Creator:Lim, Wei‐Wen ; Corden, Ben ; Ye, Lei ; Viswanathan, Sivakumar ; Widjaja, Anissa A. ; Xie, Chen ; Su, Liping ; Tee, Nicole G. Z. ; Schafer, Sebastian ; Cook, Stuart A.
Publisher:Australia: Wiley Subscription Services, Inc
Journal title:Clinical and experimental pharmacology & physiology, 2021-04, Vol.48 (4), p.605-613
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Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration
Author / Creator:Ng, Benjamin ; Huang, Kevin Y. ; Pua, Chee Jian ; Viswanathan, Sivakumar ; Lim, Wei-Wen ; Kuthubudeen, Fathima F. ; Liu, Yu-Ning ; Hii, An An ; George, Benjamin L. ; Widjaja, Anissa A. ; Petretto, Enrico ; Cook, Stuart A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.8530-16, Article 8530
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Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury
Author / Creator:Dong, Jinrui ; Lim, Wei-Wen ; Shekeran, Shamini G. ; Tan, Jessie ; Lim, Sze Yun ; Goh, Joyce Wei Ting ; George, Benjamin L. ; Schafer, Sebastian ; Cook, Stuart A. ; Widjaja, Anissa A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-06, Vol.23 (13), p.7089
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Electrophysiological and Structural Remodeling of the Atria in a Mouse Model of Troponin-I Mutation Linked Hypertrophic Cardiomyopathy: Implications for Atrial Fibrillation
Author / Creator:Lim, Wei-Wen ; Neo, Melissa ; Thanigaimani, Shivshankar ; Kuklik, Pawel ; Ganesan, Anand N. ; Lau, Dennis H. ; Tsoutsman, Tatiana ; Kalman, Jonathan M. ; Semsarian, Christopher ; Saint, David A. ; Sanders, Prashanthan
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (13), p.6941
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Role of cardiac mitofusins in cardiac conduction following simulated ischemia–reperfusion
Author / Creator:Kwek, Xiu-Yi ; Hall, Andrew R. ; Lim, Wei-Wen ; Katwadi, Khairunnisa ; Soong, Poh Loong ; Grishina, Elina ; Lin, Kun-Han ; Crespo-Avilan, Gustavo ; Yap, En Ping ; Ismail, Nur Izzah ; Chinda, Kroekkiat ; Chung, Ying Ying ; Wei, Heming ; Shim, Winston ; Montaigne, David ; Tinker, Andrew ; Ong, Sang-Bing ; Hausenloy, Derek J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-12, Vol.12 (1), p.21049-13, Article 21049
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Circulating Interleukins as Biomarkers in Non-Small Cell Lung Cancer Patients: A Pilot Study Compared to Normal Individuals
Author / Creator:Lim, Wei-Wen ; Leung, Jason H. ; Xie, Chen ; Cheng, Angelina W. T. ; Su, Liping ; Lum, Luh-Nah ; Toh, Aishah ; Kong, Siew-Ching ; Takano, Angela M. ; Hausenloy, Derek J. ; Chua, Yang C.
Publisher:Switzerland: MDPI AG
Journal title:Diseases, 2024-09, Vol.12 (9), p.221
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ArticlesPeer ReviewedFull Text
Slowed atrial and atrioventricular conduction and depressed HRV in a murine model of hypertrophic cardiomyopathy
Author / Creator:Lim, Wei-Wen ; Baumert, Mathias ; Neo, Melissa ; Kuklik, Pawel ; Ganesan, Anand N ; Lau, Dennis H ; Tsoutsman, Tatiana ; Semsarian, Christopher ; Sanders, Prashanthan ; Saint, David A
Publisher:Australia: Blackwell Publishing Ltd
Journal title:Clinical and experimental pharmacology & physiology, 2016-01, Vol.43 (1), p.95-101
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Simultaneous conduction mapping and intracellular membrane potential recording in isolated atria
Author / Creator:Neo, Melissa ; Morris, David G ; Kuklik, Pawel ; Lau, Dennis H ; Dimitri, Hany ; Lim, Wei-Wen ; Sanders, Prashanthan ; Saint, David A
Publisher:Canada: NRC Research Press
Journal title:Canadian journal of physiology and pharmacology, 2016-05, Vol.94 (5), p.563-569
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Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
Author / Creator:Dong, Jinrui ; Viswanathan, Sivakumar ; Adami, Eleonora ; Singh, Brijesh K. ; Chothani, Sonia P. ; Ng, Benjamin ; Lim, Wei Wen ; Zhou, Jin ; Tripathi, Madhulika ; Ko, Nicole S. J. ; Shekeran, Shamini G. ; Tan, Jessie ; Lim, Sze Yun ; Wang, Mao ; Lio, Pei Min ; Yen, Paul M. ; Schafer, Sebastian ; Cook, Stuart A. ; Widjaja, Anissa A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.66-15, Article 66
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BS03 Interleukin-11: pro-inflammatory, profibrotic and cardiotoxic – a new therapeutic target in heart failure
Author / Creator:Sweeney, Mark ; O’Fee, Katie ; Villanueva-Hayes, Chelsie ; Rahman, Ekhlas ; Lee, Michael ; Maatz, Henrike ; Lindberg, Eric ; Vanezis, Konstantinos ; Andrew, Ivan ; Lim, Wei-Wen ; Widjaja, Anissa ; Hubner, Norbert ; Barton, Paul ; Cook, Stuart
Publisher:London: BMJ Publishing Group Ltd and British Cardiovascular Society
Journal title:Heart (British Cardiac Society), 2024-06, Vol.110 (Suppl 3), p.246-247
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The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids
Author / Creator:Low, Ronnie Ren Jie ; Lim, Wei Wen ; Nguyen, Paul M. ; Lee, Belinda ; Christie, Michael ; Burgess, Antony W. ; Gibbs, Peter ; Grimmond, Sean M. ; Hollande, Frédéric ; Putoczki, Tracy L.
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-10, Vol.13 (19), p.4979
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Resistive straight leg raise test, resistive forward bend test and heel compression test: novel techniques in identifying secondary gain motives in low back pain cases
Author / Creator:Kumar, Naresh ; Wijerathne, Sujith Indeewara ; Lim, Wen Wei Julian ; Barry, Tan Wei Loong ; Nath, Chinmay ; Liang, Shen
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:European spine journal, 2012-11, Vol.21 (11), p.2280-2286
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IL-11 is a crucial determinant of cardiovascular fibrosis
Author / Creator:Schafer, Sebastian ; Viswanathan, Sivakumar ; Widjaja, Anissa A. ; Lim, Wei-Wen ; Moreno-Moral, Aida ; DeLaughter, Daniel M. ; Ng, Benjamin ; Patone, Giannino ; Chow, Kingsley ; Khin, Ester ; Tan, Jessie ; Chothani, Sonia P. ; Ye, Lei ; Rackham, Owen J. L. ; Ko, Nicole S. J. ; Sahib, Norliza E. ; Pua, Chee Jian ; Zhen, Nicole T. G. ; Xie, Chen ; Wang, Mao ; Maatz, Henrike ; Lim, Shiqi ; Saar, Kathrin ; Blachut, Susanne ; Petretto, Enrico ; Schmidt, Sabine ; Putoczki, Tracy ; Guimarães-Camboa, Nuno ; Wakimoto, Hiroko ; van Heesch, Sebastiaan ; Sigmundsson, Kristmundur ; Lim, See L. ; Soon, Jia L. ; Chao, Victor T. T. ; Chua, Yeow L. ; Tan, Teing E. ; Evans, Sylvia M. ; Loh, Yee J. ; Jamal, Muhammad H. ; Ong, Kim K. ; Chua, Kim C. ; Ong, Boon-Hean ; Chakaramakkil, Mathew J. ; Seidman, Jonathan G. ; Seidman, Christine E. ; Hubner, Norbert ; Sin, Kenny Y. K. ; Cook, Stuart A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7683), p.110-115
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Identification of a targetable ST2-expressing fibroblast subset driving Peutz-Jeghers syndrome polyposis
Author / Creator:Domenech-Moreno, Eva ; Wei-Wen, Lim ; Brandt, Anders ; Lemmetyinen, Toni ; Viitala, Emma ; Makela, Tomi P ; Cook, Stuart ; Ollila, Saara
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2024-01
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Showing 1 to 20 of 31 results

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IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues

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Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice

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Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease

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IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis

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Interleukin-11: A Potential Biomarker and Molecular Therapeutic Target in Non-Small Cell Lung Cancer

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Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction

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Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload

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Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration

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Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury

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Electrophysiological and Structural Remodeling of the Atria in a Mouse Model of Troponin-I Mutation Linked Hypertrophic Cardiomyopathy: Implications for Atrial Fibrillation

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Role of cardiac mitofusins in cardiac conduction following simulated ischemia–reperfusion

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Circulating Interleukins as Biomarkers in Non-Small Cell Lung Cancer Patients: A Pilot Study Compared to Normal Individuals

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Slowed atrial and atrioventricular conduction and depressed HRV in a murine model of hypertrophic cardiomyopathy

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Simultaneous conduction mapping and intracellular membrane potential recording in isolated atria

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Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH

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BS03 Interleukin-11: pro-inflammatory, profibrotic and cardiotoxic – a new therapeutic target in heart failure

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The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids

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Resistive straight leg raise test, resistive forward bend test and heel compression test: novel techniques in identifying secondary gain motives in low back pain cases

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IL-11 is a crucial determinant of cardiovascular fibrosis

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Identification of a targetable ST2-expressing fibroblast subset driving Peutz-Jeghers syndrome polyposis

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