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Platelet-derived HMGB1 is a critical mediator of thrombosis

Platelet-derived HMGB1 is a critical mediator of thrombosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665785

Platelet-derived HMGB1 is a critical mediator of thrombosis

About this item

Full title

Platelet-derived HMGB1 is a critical mediator of thrombosis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4638-4654

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Thrombosis and inflammation are intricately linked in several major clinical disorders, including disseminated intravascular coagulation and acute ischemic events. The damage-associated molecular pattern molecule high-mobility group box 1 (HMGB1) is upregulated by activated platelets in multiple inflammatory diseases; however, the contribution of p...

Alternative Titles

Full title

Platelet-derived HMGB1 is a critical mediator of thrombosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665785

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665785

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI81660

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