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ArticlesPeer ReviewedFull Text
The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells
Author / Creator:Greve, Gabriele ; Schiffmann, Insa ; Pfeifer, Dietmar ; Pantic, Milena ; Schüler, Julia ; Lübbert, Michael
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2015-12, Vol.15 (1), p.947-947, Article 947
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First-in-human study of WT1 recombinant protein vaccination in elderly patients with AML in remission: a single-center experience
Author / Creator:Kreutmair, Stefanie ; Pfeifer, Dietmar ; Waterhouse, Miguel ; Takács, Ferenc ; Graessel, Linda ; Döhner, Konstanze ; Duyster, Justus ; Illert, Anna Lena ; Frey, Anna-Verena ; Schmitt, Michael ; Lübbert, Michael
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2022-12, Vol.71 (12), p.2913-2928
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ArticlesPeer ReviewedFull Text
Donor lymphocyte infusions after first allogeneic hematopoietic stem-cell transplantation in adults with acute myeloid leukemia: a single-center landmark analysis
Author / Creator:Rettig, Andrés R. ; Ihorst, Gabriele ; Bertz, Hartmut ; Lübbert, Michael ; Marks, Reinhard ; Waterhouse, Miguel ; Wäsch, Ralph ; Zeiser, Robert ; Duyster, Justus ; Finke, Jürgen
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2021-09, Vol.100 (9), p.2339-2350
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ArticlesPeer ReviewedFull Text
Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial
Author / Creator:Cicconi, Laura ; Platzbecker, Uwe ; Avvisati, Giuseppe ; Paoloni, Francesca ; Thiede, Christian ; Vignetti, Marco ; Fazi, Paola ; Ferrara, Felicetto ; Divona, Mariadomenica ; Albano, Francesco ; Efficace, Fabio ; Sborgia, Marco ; Di Bona, Eros ; Breccia, Massimo ; Borlenghi, Erika ; Cairoli, Roberto ; Rambaldi, Alessandro ; Melillo, Lorella ; La Nasa, Giorgio ; Fiedler, Walter ; Brossart, Peter ; Hertenstein, Bernd ; Salih, Helmut R. ; Annibali, Ombretta ; Wattad, Mohammed ; Lubbert, Michael ; Brandts, Christian H. ; Hanel, Mathias ; Rollig, Christoph ; Schmitz, Norbert ; Link, Hartmut ; Frairia, Chiara ; Fozza, Claudio ; Maria D’Arco, Alfonso ; Di Renzo, Nicola ; Cortelezzi, Agostino ; Fabbiano, Francesco ; Dohner, Konstanze ; Ganser, Arnold ; Dohner, Hartmut ; Amadori, Sergio ; Mandelli, Franco ; Voso, Maria Teresa ; Ehninger, Gerhard ; Schlenk, Richard F. ; Lo-Coco, Francesco
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-03, Vol.34 (3), p.914-918
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Clonal hematopoiesis of indeterminate potential in older patients having received an allogeneic stem cell transplantation from young donors
Author / Creator:Heumüller, Anezka ; Wehrle, Julius ; Stosch, Juliane ; Niemöller, Christoph ; Bleul, Sabine ; Waterhouse, Miguel ; Uhl, David ; Metzeler, Klaus H. ; Lübbert, Michael ; Duyster, Justus ; Finke, Jürgen ; Becker, Heiko
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2020-03, Vol.55 (3), p.665-668
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ArticlesPeer ReviewedFull Text
The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression
Author / Creator:Gentle, Ian Edward ; Moelter, Isabel ; Badr, Mohamed Tarek ; Döhner, Konstanze ; Lübbert, Michael ; Häcker, Georg
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-07, Vol.12 (7), p.675-675, Article 675
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ArticlesPeer ReviewedFull Text
Treatment of therapy-related acute myeloid leukemia and underlying multiple myeloma with decitabine/venetoclax and daratumumab
Author / Creator:Shoumariyeh, Khalid ; Jung, Johannes ; Rassner, Michael ; Dold, Sandra Maria ; Riebl, Veronika ; Pantic, Milena ; Herget, Georg ; Marks, Reinhard ; Lübbert, Michael ; Wäsch, Ralph ; Engelhardt, Monika
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2021-06, Vol.100 (6), p.1637-1640
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ArticlesPeer ReviewedFull Text
Integrative study of EZH2 mutational status, copy number, protein expression and H3K27 trimethylation in AML/MDS patients
Author / Creator:Stomper, Julia ; Meier, Ruth ; Ma, Tobias ; Pfeifer, Dietmar ; Ihorst, Gabriele ; Blagitko-Dorfs, Nadja ; Greve, Gabriele ; Zimmer, Dennis ; Platzbecker, Uwe ; Hagemeijer, Anne ; Schmitt-Graeff, Ingrid ; Lübbert, Michael
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2021-04, Vol.13 (1), p.77-77, Article 77
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ArticlesPeer ReviewedFull Text
Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
Author / Creator:Niemöller, Christoph ; Wehrle, Julius ; Riba, Julian ; Claus, Rainer ; Renz, Nathalie ; Rhein, Janika ; Bleul, Sabine ; Stosch, Juliane M. ; Duyster, Justus ; Plass, Christoph ; Lutsik, Pavlo ; Lipka, Daniel B. ; Lübbert, Michael ; Becker, Heiko
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-02, Vol.4 (1), p.153-153, Article 153
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ArticlesPeer ReviewedFull Text
Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
Author / Creator:Morera, Ludovica ; Lübbert, Michael ; Jung, Manfred
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2016-05, Vol.8 (1), p.57-57, Article 57
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ArticlesPeer ReviewedFull Text
Survival Improvement over Time of 960 s-AML Patients Included in 13 EORTC-GIMEMA-HOVON Trials
Author / Creator:Ramadan, Safaa M. ; Suciu, Stefan ; Stevens-Kroef, Marian J. P. L. ; Willemze, Roelof ; Amadori, Sergio ; de Witte, Theo ; Löwenberg, Bob ; Muus, Petra ; Labar, Boris ; Meert, Liv ; de Schaetzen, Gaetan ; Meloni, Giovanna ; Leone, Giuseppe ; Vignetti, Marco ; Marie, Jean-Pierre ; Lübbert, Michael ; Baron, Frédéric
Publisher:Basel: MDPI AG
Journal title:Cancers, 2020-11, Vol.12 (11), p.3334
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ArticlesPeer ReviewedFull Text
Decitabine versus best supportive care in older patients with refractory anemia with excess blasts in transformation (RAEBt) - results of a subgroup analysis of the randomized phase III study 06011 of...
Author / Creator:Becker, Heiko ; Suciu, Stefan ; Rüter, Björn Hans ; Platzbecker, Uwe ; Giagounidis, Aristoteles ; Selleslag, Dominik ; Labar, Boris ; Germing, Ulrich ; Salih, Helmut R. ; Muus, Petra ; Pflüger, Karl-Heinz ; Hagemeijer, Anne ; Schaefer, Hans-Eckart ; Fiaccadori, Valeria ; Baron, Frédéric ; Ganser, Arnold ; Aul, Carlo ; de Witte, Theo ; Wijermans, Pierre W. ; Lübbert, Michael
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2015-12, Vol.94 (12), p.2003-2013
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ArticlesPeer ReviewedFull Text
Hypomethylating agents (HMA) for the treatment of acute myeloid leukemia and myelodysplastic syndromes: mechanisms of resistance and novel HMA-based therapies
Author / Creator:Stomper, Julia ; Rotondo, John Charles ; Greve, Gabriele ; Lübbert, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-07, Vol.35 (7), p.1873-1889
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ArticlesPeer ReviewedFull Text
Clinical development of demethylating agents in hematology
Author / Creator:Navada, Shyamala C. ; Steinmann, Juliane ; Lübbert, Michael ; Silverman, Lewis R.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-01, Vol.124 (1), p.40-46
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ArticlesPeer ReviewedFull Text
AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms
Author / Creator:Rejeski, Kai ; Duque-Afonso, Jesús ; Lübbert, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-09, Vol.40 (38), p.5665-5676
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ArticlesPeer ReviewedFull Text
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
Author / Creator:Wagner, Julia M. ; Hackanson, Björn ; Lübbert, Michael ; Jung, Manfred
Publisher:Germany: Springer-Verlag
Journal title:Clinical epigenetics, 2010-12, Vol.1 (3-4), p.117-136
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ArticlesPeer ReviewedFull Text
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Author / Creator:Brocks, David ; Schmidt, Christopher R ; Daskalakis, Michael ; Jang, Hyo Sik ; Shah, Nakul M ; Li, Daofeng ; Li, Jing ; Zhang, Bo ; Hou, Yiran ; Laudato, Sara ; Lipka, Daniel B ; Schott, Johanna ; Bierhoff, Holger ; Assenov, Yassen ; Helf, Monika ; Ressnerova, Alzbeta ; Islam, Md Saiful ; Lindroth, Anders M ; Haas, Simon ; Essers, Marieke ; Imbusch, Charles D ; Brors, Benedikt ; Oehme, Ina ; Witt, Olaf ; Lübbert, Michael ; Mallm, Jan-Philipp ; Rippe, Karsten ; Will, Rainer ; Weichenhan, Dieter ; Stoecklin, Georg ; Gerhäuser, Clarissa ; Oakes, Christopher C ; Wang, Ting ; Plass, Christoph
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-07, Vol.49 (7), p.1052-1060
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ArticlesPeer ReviewedFull Text
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts
Author / Creator:Goyal, Ashish ; Bauer, Jens ; Hey, Joschka ; Papageorgiou, Dimitris N. ; Stepanova, Ekaterina ; Daskalakis, Michael ; Scheid, Jonas ; Dubbelaar, Marissa ; Klimovich, Boris ; Schwarz, Dominic ; Märklin, Melanie ; Roerden, Malte ; Lin, Yu-Yu ; Ma, Tobias ; Mücke, Oliver ; Rammensee, Hans-Georg ; Lübbert, Michael ; Loayza-Puch, Fabricio ; Krijgsveld, Jeroen ; Walz, Juliane S. ; Plass, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6731-19, Article 6731
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Newsletter articlesFull Text
Published Clinical Study of SuperGen's Decitabine Confirms Drug's Novel Mechanism of Action
Publisher:New York: PR Newswire Association LLC
Journal title:PR Newswire, 2002, p.1
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ArticlesPeer ReviewedFull Text
Absence of early platelet increment in healthy mice during decitabine treatment
Author / Creator:Baumann, Juliane ; Spindler, Markus ; Throm, Yannick ; Lübbert, Michael ; Bender, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-12, Vol.12 (1), p.22266-7, Article 22266
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The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells

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First-in-human study of WT1 recombinant protein vaccination in elderly patients with AML in remission: a single-center experience

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Donor lymphocyte infusions after first allogeneic hematopoietic stem-cell transplantation in adults with acute myeloid leukemia: a single-center landmark analysis

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Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

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Clonal hematopoiesis of indeterminate potential in older patients having received an allogeneic stem cell transplantation from young donors

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The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

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Treatment of therapy-related acute myeloid leukemia and underlying multiple myeloma with decitabine/venetoclax and daratumumab

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Integrative study of EZH2 mutational status, copy number, protein expression and H3K27 trimethylation in AML/MDS patients

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Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

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Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy

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Survival Improvement over Time of 960 s-AML Patients Included in 13 EORTC-GIMEMA-HOVON Trials

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Decitabine versus best supportive care in older patients with refractory anemia with excess blasts in transformation (RAEBt) - results of a subgroup analysis of the randomized phase III study 06011 of...

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Hypomethylating agents (HMA) for the treatment of acute myeloid leukemia and myelodysplastic syndromes: mechanisms of resistance and novel HMA-based therapies

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Clinical development of demethylating agents in hematology

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AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms

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Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy

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DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

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DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts

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Published Clinical Study of SuperGen's Decitabine Confirms Drug's Novel Mechanism of Action

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Absence of early platelet increment in healthy mice during decitabine treatment

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