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ArticlesPeer ReviewedFull Text
Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances
Author / Creator:Zundler, Sebastian ; Becker, Emily ; Schulze, Lisa Lou ; Neurath, Markus F
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2019-09, Vol.68 (9), p.1688-1700
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Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial
Author / Creator:Vermeire, Séverine, Prof ; Sandborn, William J, Prof ; Danese, Silvio, Prof ; Hébuterne, Xavier, Prof ; Salzberg, Bruce A, MD ; Klopocka, Maria, MD ; Tarabar, Dino, MD ; Vanasek, Tomas, MD ; Greguš, Miloš, MD ; Hellstern, Paul A, MD ; Kim, Joo Sung, MD ; Sparrow, Miles P, MBBS ; Gorelick, Kenneth J, MD ; Hinz, Michelle, MS ; Ahmad, Alaa, PhD ; Pradhan, Vivek, MS ; Hassan-Zahraee, Mina, PhD ; Clare, Robert, PhD ; Cataldi, Fabio, MD ; Reinisch, Walter, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-07, Vol.390 (10090), p.135-144
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Transcriptional derepression of CHD4/NuRD-regulated genes in the muscle of patients with dermatomyositis and anti-Mi2 autoantibodies
Author / Creator:Pinal-Fernandez, Iago ; Milisenda, Jose Cesar ; Pak, Katherine ; Muñoz-Braceras, Sandra ; Casal-Dominguez, Maria ; Torres-Ruiz, Jiram ; Dell'Orso, Stefania ; Naz, Faiza ; Gutierrez-Cruz, Gustavo ; Duque-Jaimez, Yaiza ; Matas-Garcia, Ana ; Padrosa, Joan ; Garcia-Garcia, Francesc J ; Guitart-Mampel, Mariona ; Garrabou, Gloria ; Trallero-Araguás, Ernesto ; Walitt, Brian ; Paik, Julie J ; Albayda, Jemima ; Christopher-Stine, Lisa ; Lloyd, Thomas E ; Grau-Junyent, Josep Maria ; Selva-O'Callaghan, Albert ; Mammen, Andrew Lee
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2023-08, Vol.82 (8), p.1091-1097
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Carotegrast Methyl: First Approval
Author / Creator:Dhillon, Sohita
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2022-06, Vol.82 (9), p.1011-1016
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The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7
Author / Creator:Van Ryk, Donald ; Vimonpatranon, Sinmanus ; Hiatt, Joe ; Ganesan, Sundar ; Chen, Nathalie ; McMurry, Jordan ; Garba, Saadiq ; Min, Susie ; Goes, Livia R. ; Girard, Alexandre ; Yolitz, Jason ; Licavoli, Isabella ; Wei, Danlan ; Huang, Dawei ; Soares, Marcelo A. ; Martinelli, Elena ; Cicala, Claudia ; Arthos, James
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-12, Vol.19 (12), p.e1011860-e1011860
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Oral reovirus reshapes the gut microbiome and enhances antitumor immunity in colon cancer
Author / Creator:Lee, Won Suk ; Lee, Seung Joon ; Lee, Hye Jin ; Yang, Hannah ; Go, Eun-Jin ; Gansukh, Enkhtaivan ; Song, Ki-Hoon ; Xiang, Xiao ; Park, Dong Guk ; Alain, Tommy ; Chon, Hong Jae ; Kim, Chan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.9092-15, Article 9092
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P129 Efficacy and safety of vedolizumab for inflammatory bowel disease in the uk population:single centre experience
Author / Creator:Aleem, Muhammad Junaid ; Mozdiak, Ella ; Saeed, Omar Muhammad ; Champsi, Asgher ; Hameed, Kashif ; Lakhani, Hammad ; Monga, Muhammad Ali
Publisher:London: BMJ Publishing Group LTD
Journal title:Gut, 2021-01, Vol.70 (Suppl 1), p.A109-A109
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MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4+ T cells into CCR5+ TRM-like cells
Author / Creator:Vimonpatranon, Sinmanus ; Goes, Livia R. ; Chan, Amanda ; Licavoli, Isabella ; McMurry, Jordan ; Wertz, Samuel R. ; Arakelyan, Anush ; Huang, Dawei ; Jiang, Andrew ; Huang, Cindy ; Zhou, Joyce ; Yolitz, Jason ; Girard, Alexandre ; Van Ryk, Donald ; Wei, Danlan ; Hwang, Il Young ; Martens, Craig ; Kanakabandi, Kishore ; Virtaneva, Kimmo ; Ricklefs, Stacy ; Darwitz, Benjamin P. ; Soares, Marcelo A. ; Pattanapanyasat, Kovit ; Fauci, Anthony S. ; Arthos, James ; Cicala, Claudia
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-03, Vol.19 (3), p.e1011209-e1011209
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TRPV1 controls innate immunity during Citrobacter rodentium enteric infection
Author / Creator:Cremin, Michael ; Tay, Emmy Xue Yun ; Ramirez, Valerie T. ; Murray, Kaitlin ; Nichols, Rene K. ; Brust-Mascher, Ingrid ; Reardon, Colin
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-12, Vol.19 (12), p.e1011576-e1011576
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Mechanism of action of vedolizumab: do we really understand it?
Author / Creator:Rogler, Gerhard
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2019-01, Vol.68 (1), p.4-5
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Inflammation responsive tofacitinib loaded albumin nanomedicine for targeted synergistic therapy in ulcerative colitis
Author / Creator:Li, Bang ; Liu, Xiaoyan ; Long, Qi ; Zhuang, Xiaoduan ; Gao, Yanfei ; Ali, Barkat ; Chen, Haoting ; Zhang, Dongyang ; Wang, Xinying ; Guo, Weisheng
Publisher:Beijing: Tsinghua University Press
Journal title:Nano research, 2023-07, Vol.16 (7), p.9873-9884
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Safety and effectiveness of vedolizumab in paediatric patients with inflammatory bowel disease: an observational multicentre Spanish study
Author / Creator:Garcia-Romero, Ruth ; Martinez de Zabarte Fernandez, José Miguel ; Pujol-Muncunill, Gemma ; Donat-Aliaga, Ester ; Segarra-Cantón, Oscar ; Irastorza-Terradillos, Iñaki ; Medina-Benitez, Enrique ; Ruiz-Hernández, Carlos José ; Carrillo-Palau, Marta ; Ros-Arnal, Ignacio ; Rodriguez-Martínez, Alejandro ; Escartin-Madurga, Laura ; Gutiérrez-Junquera, Carolina ; Vicente-Santamaría, Saioa ; Velasco Rodriguez-Belvis, Marta ; Fernández-Fernández, Sonia ; Alberto-Alonso, José Ramón ; Montraveta, Montserrat ; Torres-Peral, Ricardo ; Navalon-Rubio, María ; Navas-López, Víctor Manuel ; Martin de Carpi, Javier
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of pediatrics, 2021-09, Vol.180 (9), p.3029-3038
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Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis
Author / Creator:Gao, Rachel Y. ; Shearn, Colin T. ; Orlicky, David J. ; Battista, Kayla D. ; Alexeev, Erica E. ; Cartwright, Ian M. ; Lanis, Jordi M. ; Kostelecky, Rachael E. ; Ju, Cynthia ; Colgan, Sean P. ; Fennimore, Blair P.
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2021-03, Vol.14 (2), p.479-490
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Circulating exosomes express α4β7 integrin and compete with CD4+ T cells for the binding to Vedolizumab
Author / Creator:Domenis, Rossana ; Marino, Marco ; Cifù, Adriana ; Scardino, Giulia ; Curcio, Francesco ; Fabris, Martina
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-11, Vol.15 (11), p.e0242342-e0242342
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A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis
Author / Creator:Zhang, Hailong ; Zheng, Yajuan ; Pan, Youdong ; Lin, Changdong ; Wang, Shihui ; Yan, Zhanjun ; Lu, Ling ; Ge, Gaoxiang ; Li, Jinsong ; Zeng, Yi Arial ; Chen, Jianfeng
Publisher:London: BioMed Central
Journal title:BMC biology, 2020-06, Vol.18 (1), p.1-64, Article 64
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Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis
Author / Creator:Tyler, Christopher J. ; Guzman, Mauricio ; Lundborg, Luke R. ; Yeasmin, Shaila ; Zgajnar, Nadia ; Jedlicka, Paul ; Bamias, Giorgos ; Rivera-Nieves, Jesús
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2022-01, Vol.15 (1), p.109-119
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Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies
Author / Creator:Sato, Tsuyoshi ; Ishihara, Sayaka ; Marui, Ryoya ; Takagi, Junichi ; Katagiri, Koko
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-08, Vol.10 (1), p.13221-13221, Article 13221
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Identification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor
Author / Creator:Peachman, Kristina K. ; Karasavvas, Nicos ; Chenine, Agnes-Laurence ; McLinden, Robert ; Rerks-Ngarm, Supachai ; Jaranit, Kaewkungwal ; Nitayaphan, Sorachai ; Pitisuttithum, Punnee ; Tovanabutra, Sodsai ; Zolla-Pazner, Susan ; Michael, Nelson L. ; Kim, Jerome H. ; Alving, Carl R. ; Rao, Mangala
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-12, Vol.10 (12), p.e0143895-e0143895
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MAdCAM-1 mediates retinal neuron degeneration in experimental colitis through recruiting gut-homing CD4+ T cells
Author / Creator:Peng, Kun ; Xiao, Jie ; Wang, Jinxia ; Song, Yaxin ; Wu, Lianying ; Xiu, Wenbo ; Chen, Qinyuan ; Chen, Yanxi ; Shuai, Ping ; He, Chong ; Lu, Fang
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2021-01, Vol.14 (1), p.152-163
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The Omentum in Obesity-Associated Cancer: A Hindrance to Effective Natural Killer Cell Migration towards Tumour Which Can Be Overcome by CX3CR1 Antagonism
Author / Creator:Mylod, Eimear ; O’Connell, Fiona ; Donlon, Noel E. ; Butler, Christine ; Reynolds, John V. ; Lysaght, Joanne ; Conroy, Melissa J.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-12, Vol.14 (1), p.64
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Showing 1 to 20 of 53 results

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Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances

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Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial

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Transcriptional derepression of CHD4/NuRD-regulated genes in the muscle of patients with dermatomyositis and anti-Mi2 autoantibodies

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Carotegrast Methyl: First Approval

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The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7

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Oral reovirus reshapes the gut microbiome and enhances antitumor immunity in colon cancer

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P129 Efficacy and safety of vedolizumab for inflammatory bowel disease in the uk population:single centre experience

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MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4+ T cells into CCR5+ TRM-like cells

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TRPV1 controls innate immunity during Citrobacter rodentium enteric infection

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Mechanism of action of vedolizumab: do we really understand it?

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Inflammation responsive tofacitinib loaded albumin nanomedicine for targeted synergistic therapy in ulcerative colitis

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Safety and effectiveness of vedolizumab in paediatric patients with inflammatory bowel disease: an observational multicentre Spanish study

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Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis

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Circulating exosomes express α4β7 integrin and compete with CD4+ T cells for the binding to Vedolizumab

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A mutation that blocks integrin α4β7 activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis

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Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis

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Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies

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Identification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor

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MAdCAM-1 mediates retinal neuron degeneration in experimental colitis through recruiting gut-homing CD4+ T cells

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The Omentum in Obesity-Associated Cancer: A Hindrance to Effective Natural Killer Cell Migration towards Tumour Which Can Be Overcome by CX3CR1 Antagonism

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