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38 results for Myeloid+Cells+-+enzymology

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ArticlesPeer ReviewedFull Text
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
Author / Creator:Kornberg, Michael D ; Bhargava, Pavan ; Kim, Paul M ; Putluri, Vasanta ; Snowman, Adele M ; Putluri, Nagireddy ; Calabresi, Peter A ; Snyder, Solomon H
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6387), p.449-453
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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
Author / Creator:De Henau, Olivier ; Rausch, Matthew ; Winkler, David ; Campesato, Luis Felipe ; Liu, Cailian ; Cymerman, Daniel Hirschhorn ; Budhu, Sadna ; Ghosh, Arnab ; Pink, Melissa ; Tchaicha, Jeremy ; Douglas, Mark ; Tibbitts, Thomas ; Sharma, Sujata ; Proctor, Jennifer ; Kosmider, Nicole ; White, Kerry ; Stern, Howard ; Soglia, John ; Adams, Julian ; Palombella, Vito J. ; McGovern, Karen ; Kutok, Jeffery L. ; Wolchok, Jedd D. ; Merghoub, Taha
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-11, Vol.539 (7629), p.443-447
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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
Author / Creator:Vasquez-Dunddel, David ; Pan, Fan ; Zeng, Qi ; Gorbounov, Mikhail ; Albesiano, Emilia ; Fu, Juan ; Blosser, Richard L ; Tam, Ada J ; Bruno, Tullia ; Zhang, Hao ; Pardoll, Drew ; Kim, Young
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-04, Vol.123 (4), p.1580-1589
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Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment
Author / Creator:Su, Xinming ; Xu, Yalin ; Fox, Gregory C ; Xiang, Jingyu ; Kwakwa, Kristin A ; Davis, Jennifer L ; Belle, Jad I ; Lee, Wen-Chih ; Wong, Wing H ; Fontana, Francesca ; Hernandez-Aya, Leonel F ; Kobayashi, Takayuki ; Tomasson, Helen M ; Su, Junyi ; Bakewell, Suzanne J ; Stewart, Sheila A ; Egbulefu, Christopher ; Karmakar, Partha ; Meyer, Melisa A ; Veis, Deborah J ; DeNardo, David G ; Lanza, Gregory M ; Achilefu, Samuel ; Weilbaecher, Katherine N
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-10, Vol.131 (20), p.1-17
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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment
Author / Creator:Steggerda, Susanne M ; Bennett, Mark K ; Chen, Jason ; Emberley, Ethan ; Huang, Tony ; Janes, Julie R ; Li, Weiqun ; MacKinnon, Andrew L ; Makkouk, Amani ; Marguier, Gisele ; Murray, Peter J ; Neou, Silinda ; Pan, Alison ; Parlati, Francesco ; Rodriguez, Mirna L M ; Van de Velde, Lee-Ann ; Wang, Tracy ; Works, Melissa ; Zhang, Jing ; Zhang, Winter ; Gross, Matthew I
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2017-12, Vol.5 (1), p.101-101, Article 101
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Regulation of immune responses by L-arginine metabolism
Author / Creator:Bronte, Vincenzo ; Zanovello, Paola
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2005-08, Vol.5 (8), p.641-654
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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
Author / Creator:Matmati, Mourad ; Jacques, Peggy ; Maelfait, Jonathan ; Verheugen, Eveline ; Kool, Mirjam ; Sze, Mozes ; Geboes, Lies ; Louagie, Els ; Guire, Conor Mc ; Vereecke, Lars ; Chu, Yuanyuan ; Boon, Louis ; Staelens, Steven ; Matthys, Patrick ; Lambrecht, Bart N ; Schmidt-Supprian, Marc ; Pasparakis, Manolis ; Elewaut, Dirk ; Beyaert, Rudi ; van Loo, Geert
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-09, Vol.43 (9), p.908-912
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Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation
Author / Creator:Jacquel, Arnaud ; Luciano, Frederic ; Robert, Guillaume ; Auberger, Patrick
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2018-09, Vol.19 (10), p.2991
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Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects
Author / Creator:Frenis, Katie ; Helmstädter, Johanna ; Ruan, Yue ; Schramm, Eva ; Kalinovic, Sanela ; Kröller-Schön, Swenja ; Bayo Jimenez, Maria Teresa ; Hahad, Omar ; Oelze, Matthias ; Jiang, Subao ; Wenzel, Philip ; Sommer, Clemens J. ; Frauenknecht, Katrin B. M. ; Waisman, Ari ; Gericke, Adrian ; Daiber, Andreas ; Münzel, Thomas ; Steven, Sebastian
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2021-12, Vol.116 (1), p.31, Article 31
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ArticlesPeer ReviewedFull Text
Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity
Author / Creator:Miret, Juan J ; Kirschmeier, Paul ; Koyama, Shohei ; Zhu, Mingrui ; Li, Yvonne Y ; Naito, Yujiro ; Wu, Min ; Malladi, Venkat S ; Huang, Wei ; Walker, William ; Palakurthi, Sangeetha ; Dranoff, Glenn ; Hammerman, Peter S ; Pecot, Chad V ; Wong, Kwok-Kin ; Akbay, Esra A
Publisher:England: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2019-02, Vol.7 (1), p.32-32, Article 32
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ArticlesPeer ReviewedFull Text
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans
Author / Creator:De Santo, Carmela ; Salio, Mariolina ; Masri, S Hajar ; Lee, Laurel Yong-Hwa ; Dong, Tao ; Speak, Anneliese O ; Porubsky, Stefan ; Booth, Sarah ; Veerapen, Natacha ; Besra, Gurdyal S ; Gröne, Hermann-Josef ; Platt, Frances M ; Zambon, Maria ; Cerundolo, Vincenzo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2008-12, Vol.118 (12), p.4036-4048
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ArticlesPeer ReviewedFull Text
Myeloid/Microglial Driven Autologous Hematopoietic Stem Cell Gene Therapy Corrects a Neuronopathic Lysosomal Disease
Author / Creator:Sergijenko, Ana ; Langford-Smith, Alexander ; Liao, Ai Y ; Pickford, Claire E ; McDermott, John ; Nowinski, Gabriel ; Langford-Smith, Kia J ; Merry, Catherine LR ; Jones, Simon A ; Wraith, J Edmond ; Wynn, Robert F ; Wilkinson, Fiona L ; Bigger, Brian W
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2013-10, Vol.21 (10), p.1938-1949
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ArticlesPeer ReviewedFull Text
Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage
Author / Creator:Weiss, Stefanie A I ; Rehm, Salome R T ; Perera, Natascha C ; Biniossek, Martin L ; Schilling, Oliver ; Jenne, Dieter E
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-02, Vol.22 (4), p.1658
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Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection
Author / Creator:Goetzke, Carl Christoph ; Althof, Nadine ; Neumaier, Hannah Louise ; Heuser, Arndt ; Kaya, Ziya ; Kespohl, Meike ; Klingel, Karin ; Beling, Antje
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2021-12, Vol.116 (1), p.7, Article 7
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Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells
Author / Creator:Sundberg, Thomas B. ; Choi, Hwan Geun ; Song, Joo-Hye ; Russell, Caitlin N. ; Hussain, Mahmud M. ; Graham, Daniel B. ; Khor, Bernard ; Gagnon, John ; O'Connell, Daniel J. ; Narayan, Kavitha ; Dančik, Vlado ; Perez, Jose R. ; Reinecker, Hans-Christian ; Gray, Nathanael S. ; Schreiber, Stuart L. ; Xavier, Ramnik J. ; Shamji, Alykhan F.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12468-12473
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Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation
Author / Creator:Wu, Yung-Hsuan ; Chou, Ting-Fang ; Young, Leslie ; Hsieh, Fu-Yi ; Pan, Hsuan-Yin ; Mo, Shu-Ting ; Brown, Shani Bialik ; Chen, Ruey-Hwa ; Kimchi, Adi ; Lai, Ming-Zong
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-05, Vol.11 (5), p.305-305, Article 305
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Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dep...
Author / Creator:GRANT, Louise ; SHEARER, Kirsty D ; MODY, Nimesh ; DELIBEGOVIC, Mirela ; CZOPEK, Alicja ; LEES, Emma K ; OWEN, Carl ; AGOUNI, Abdelali ; WORKMAN, James ; MARTIN-GRANADOS, Cristina ; FORRESTER, John V ; WILSON, Heather M
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2014-02, Vol.63 (2), p.456-470
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Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling
Author / Creator:Swarnkar, Gaurav ; Karuppaiah, Kannan ; Mbalaviele, Gabriel ; Chen, Tim (Hung-Po) ; Abu-Amer, Yousef
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (1), p.154-159
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Genetic Ablation of Hematopoietic Cell Kinase Accelerates Alzheimer’s Disease–Like Neuropathology in Tg2576 Mice
Author / Creator:Lim, Siok Lam ; Tran, Diana Nguyen ; Kieu, Zanett ; Chen, Christine ; Villanueva, Emmanuel ; Ghiaar, Sagar ; Gallup, Victoria ; Zumkehr, Joannee ; Cribbs, David H. ; Rodriguez-Ortiz, Carlos J. ; Kitazawa, Masashi
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2020-05, Vol.57 (5), p.2447-2460
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Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice
Author / Creator:Chen, Lihong ; Yang, Guangrui ; Monslow, James ; Todd, Leslie ; Cormode, David P. ; Tang, Jun ; Grant, Gregory R. ; DeLong, Jonathan H. ; Tang, Soon Yew ; Lawson, John A. ; Pure, Ellen ; FitzGerald, Garret A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6828-6833
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Showing 1 to 20 of 38 results

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Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

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Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment

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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

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Regulation of immune responses by L-arginine metabolism

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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

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Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

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Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects

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Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity

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Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans

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Myeloid/Microglial Driven Autologous Hematopoietic Stem Cell Gene Therapy Corrects a Neuronopathic Lysosomal Disease

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Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage

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Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection

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Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells

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Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

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Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dep...

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Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling

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Genetic Ablation of Hematopoietic Cell Kinase Accelerates Alzheimer’s Disease–Like Neuropathology in Tg2576 Mice

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Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice

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