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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Author / Creator:Chouchani, Edward T. ; Pell, Victoria R. ; Gaude, Edoardo ; Aksentijević, Dunja ; Sundier, Stephanie Y. ; Robb, Ellen L. ; Logan, Angela ; Nadtochiy, Sergiy M. ; Ord, Emily N. J. ; Smith, Anthony C. ; Eyassu, Filmon ; Shirley, Rachel ; Hu, Chou-Hui ; Dare, Anna J. ; James, Andrew M. ; Rogatti, Sebastian ; Hartley, Richard C. ; Eaton, Simon ; Costa, Ana S. H. ; Brookes, Paul S. ; Davidson, Sean M. ; Duchen, Michael R. ; Saeb-Parsy, Kourosh ; Shattock, Michael J. ; Robinson, Alan J. ; Work, Lorraine M. ; Frezza, Christian ; Krieg, Thomas ; Murphy, Michael P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-11, Vol.515 (7527), p.431-435
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Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
Author / Creator:Erickson, Jeffrey R. ; Pereira, Laetitia ; Wang, Lianguo ; Han, Guanghui ; Ferguson, Amanda ; Dao, Khanha ; Copeland, Ronald J. ; Despa, Florin ; Hart, Gerald W. ; Ripplinger, Crystal M. ; Bers, Donald M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-10, Vol.502 (7471), p.372-376
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Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification
Author / Creator:Vicinanza, Carla ; Aquila, Iolanda ; Scalise, Mariangela ; Cristiano, Francesca ; Marino, Fabiola ; Cianflone, Eleonora ; Mancuso, Teresa ; Marotta, Pina ; Sacco, Walter ; Lewis, Fiona C ; Couch, Liam ; Shone, Victoria ; Gritti, Giulia ; Torella, Annalaura ; Smith, Andrew J ; Terracciano, Cesare MN ; Britti, Domenico ; Veltri, Pierangelo ; Indolfi, Ciro ; Nadal-Ginard, Bernardo ; Ellison-Hughes, Georgina M ; Torella, Daniele
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-12, Vol.24 (12), p.2101-2116
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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Author / Creator:Lee, Dong I. ; Zhu, Guangshuo ; Sasaki, Takashi ; Cho, Gun-Sik ; Hamdani, Nazha ; Holewinski, Ronald ; Jo, Su-Hyun ; Danner, Thomas ; Zhang, Manling ; Rainer, Peter P. ; Bedja, Djahida ; Kirk, Jonathan A. ; Ranek, Mark J. ; Dostmann, Wolfgang R. ; Kwon, Chulan ; Margulies, Kenneth B. ; Van Eyk, Jennifer E. ; Paulus, Walter J. ; Takimoto, Eiki ; Kass, David A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-03, Vol.519 (7544), p.472-476
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Specialized roles for cysteine cathepsins in health and disease
Author / Creator:Reiser, Jochen ; Adair, Brian ; Reinheckel, Thomas
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3421-3431
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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
Author / Creator:Pillai, Vinodkumar B. ; Samant, Sadhana ; Sundaresan, Nagalingam R. ; Raghuraman, Hariharasundaram ; Kim, Gene ; Bonner, Michael Y. ; Arbiser, Jack L. ; Walker, Douglas I. ; Jones, Dean P. ; Gius, David ; Gupta, Mahesh P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-04, Vol.6 (1), p.6656-6656, Article 6656
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Physiological and unappreciated roles of CaMKII in the heart
Author / Creator:Beckendorf, Jan ; van den Hoogenhof, Maarten M. G. ; Backs, Johannes
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2018-07, Vol.113 (4), p.29-12, Article 29
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Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner
Author / Creator:Wang, Chunyan ; Zhu, Lijie ; Yuan, Wenlin ; Sun, Lingbin ; Xia, Zhengyuan ; Zhang, Zhongjun ; Yao, Weifeng
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-06, Vol.24 (12), p.6670-6679
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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
Author / Creator:Jaber, Nadia ; Dou, Zhixun ; Chen, Juei-Suei ; Catanzaro, Joseph ; Jiang, Ya-Ping ; Ballou, Lisa M ; Selinger, Elzbieta ; Ouyang, Xiaosen ; Lin, Richard Z ; Zhang, Jianhua ; Zong, Wei-Xing
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (6), p.2003-2008
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ArticlesPeer ReviewedFull Text
Functional asymmetry and electron flow in the bovine respirasome
Author / Creator:Sousa, Joana S ; Mills, Deryck J ; Vonck, Janet ; Kühlbrandt, Werner
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-11, Vol.5
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Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload
Author / Creator:Wang, Junyan ; Deng, Bo ; Liu, Qing ; Huang, Yusheng ; Chen, Weitao ; Li, Jing ; Zhou, Zheng ; Zhang, Lu ; Liang, Birong ; He, Jiaqi ; Chen, Zixin ; Yan, Cui ; Yang, Zhongqi ; Xian, Shaoxiang ; Wang, Lingjun
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-07, Vol.11 (7), p.574, Article 574
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ArticlesPeer ReviewedFull Text
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
Author / Creator:Zhang, Qing-Jun ; Tran, Tram Anh T. ; Wang, Ming ; Ranek, Mark J. ; Kokkonen-Simon, Kristen M. ; Gao, Jason ; Luo, Xiang ; Tan, Wei ; Kyrychenko, Viktoriia ; Liao, Lan ; Xu, Jianming ; Hill, Joseph A. ; Olson, Eric N. ; Kass, David A. ; Martinez, Elisabeth D. ; Liu, Zhi-Ping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-12, Vol.9 (1), p.5230-12, Article 5230
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ArticlesPeer ReviewedFull Text
A technique for in vivo mapping of myocardial creatine kinase metabolism
Author / Creator:Haris, Mohammad ; Singh, Anup ; Cai, Kejia ; Kogan, Feliks ; McGarvey, Jeremy ; DeBrosse, Catherine ; Zsido, Gerald A ; Witschey, Walter R T ; Koomalsingh, Kevin ; Pilla, James J ; Chirinos, Julio A ; Ferrari, Victor A ; Gorman, Joseph H ; Hariharan, Hari ; Gorman, Robert C ; Reddy, Ravinder
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-02, Vol.20 (2), p.209-214
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ArticlesPeer ReviewedFull Text
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart
Author / Creator:Warren, Junco S. ; Tracy, Christopher M. ; Miller, Mickey R. ; Makaju, Aman ; Szulik, Marta W. ; Oka, Shin-ichi ; Yuzyuk, Tatiana N. ; Cox, James E. ; Kumar, Anil ; Lozier, Bucky K. ; Wang, Li ; Llana, June García ; Sabry, Amira D. ; Cawley, Keiko M. ; Barton, Dane W. ; Han, Yong Hwan ; Boudina, Sihem ; Fiehn, Oliver ; Tucker, Haley O. ; Zaitsev, Alexey V. ; Franklin, Sarah
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (33), p.E7871-E7880
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PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
Author / Creator:Billia, Filio ; Hauck, Ludger ; Konecny, Filip ; Rao, Vivek ; Shen, Jie ; Mak, Tak Wah
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9572-9577
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Sublethal exposure to crude oil during embryonic development alters cardiac morphology and reduces aerobic capacity in adult fish
Author / Creator:Hicken, Corinne E ; Linbo, Tiffany L ; Baldwin, David H ; Willis, Maryjean L ; Myers, Mark S ; Holland, Larry ; Larsen, Marie ; Stekoll, Michael S ; Rice, Stanley D ; Collier, Tracy K ; Scholz, Nathaniel L ; Incardona, John P
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.7086-7090
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CaMKII determines mitochondrial stress responses in heart
Author / Creator:Joiner, Mei-ling A. ; Koval, Olha M. ; Li, Jingdong ; He, B. Julie ; Allamargot, Chantal ; Gao, Zhan ; Luczak, Elizabeth D. ; Hall, Duane D. ; Fink, Brian D. ; Chen, Biyi ; Yang, Jinying ; Moore, Steven A. ; Scholz, Thomas D. ; Strack, Stefan ; Mohler, Peter J. ; Sivitz, William I. ; Song, Long-Sheng ; Anderson, Mark E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-11, Vol.491 (7423), p.269-273
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Diabetes increases mortality after myocardial infarction by oxidizing CaMKII
Author / Creator:Luo, Min ; Guan, Xiaoqun ; Luczak, Elizabeth D ; Lang, Di ; Kutschke, William ; Gao, Zhan ; Yang, Jinying ; Glynn, Patric ; Sossalla, Samuel ; Swaminathan, Paari D ; Weiss, Robert M ; Yang, Baoli ; Rokita, Adam G ; Maier, Lars S ; Efimov, Igor R ; Hund, Thomas J ; Anderson, Mark E
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-03, Vol.123 (3), p.1262-1274
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Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'
Author / Creator:Waldman, Maayan ; Cohen, Keren ; Yadin, Dor ; Nudelman, Vadim ; Gorfil, Dan ; Laniado-Schwartzman, Michal ; Kornwoski, Ran ; Aravot, Dan ; Abraham, Nader G ; Arad, Michael ; Hochhauser, Edith
Publisher:England: BioMed Central
Journal title:Cardiovascular diabetology, 2018-08, Vol.17 (1), p.111-111, Article 111
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Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke
Author / Creator:Rohde, John A. ; Thomas, David D. ; Muretta, Joseph M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1796-E1804
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

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Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

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Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

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Specialized roles for cysteine cathepsins in health and disease

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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

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Physiological and unappreciated roles of CaMKII in the heart

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Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner

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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

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Functional asymmetry and electron flow in the bovine respirasome

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Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

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Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

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A technique for in vivo mapping of myocardial creatine kinase metabolism

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Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart

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PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

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Sublethal exposure to crude oil during embryonic development alters cardiac morphology and reduces aerobic capacity in adult fish

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CaMKII determines mitochondrial stress responses in heart

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Diabetes increases mortality after myocardial infarction by oxidizing CaMKII

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Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'

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Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke

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