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ArticlesPeer ReviewedFull Text
Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
Author / Creator:Cuadrado, Antonio ; Manda, Gina ; Fernández-Ginés, Raquel ; Robledinos-Antón, Natalia
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2019, Vol.2019 (2019), p.1-20
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NRF2 regulates serine biosynthesis in non–small cell lung cancer
Author / Creator:DeNicola, Gina M ; Chen, Pei-Hsuan ; Mullarky, Edouard ; Sudderth, Jessica A ; Hu, Zeping ; Wu, David ; Tang, Hao ; Xie, Yang ; Asara, John M ; Huffman, Kenneth E ; Wistuba, Ignacio I ; Minna, John D ; DeBerardinis, Ralph J ; Cantley, Lewis C
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2015-12, Vol.47 (12), p.1475-1481
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Potential Applications of NRF2 Inhibitors in Cancer Therapy
Author / Creator:Panieri, Emiliano ; Saso, Luciano
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2019-01, Vol.2019 (2019), p.1-34
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Luteolin Inhibits Breast Cancer Stemness and Enhances Chemosensitivity through the Nrf2-Mediated Pathway
Author / Creator:Tsai, Kuen-Jang ; Tsai, Hsin-Yi ; Tsai, Chin-Chuan ; Chen, Tai-Yu ; Hsieh, Tsung-Hua ; Chen, Chun-Lin ; Mbuyisa, Lulekiwe ; Huang, Yaw-Bin ; Lin, Ming-Wei
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-10, Vol.26 (21), p.6452
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ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis
Author / Creator:Dey, Souvik ; Sayers, Carly M ; Verginadis, Ioannis I ; Lehman, Stacey L ; Cheng, Yi ; Cerniglia, George J ; Tuttle, Stephen W ; Feldman, Michael D ; Zhang, Paul J L ; Fuchs, Serge Y ; Diehl, J Alan ; Koumenis, Constantinos
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-07, Vol.125 (7), p.2592-2592
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Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer
Author / Creator:Telkoparan-Akillilar, Pelin ; Panieri, Emiliano ; Cevik, Dilek ; Suzen, Sibel ; Saso, Luciano
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-03, Vol.26 (5), p.1417
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Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
Author / Creator:Carlström, Karl E. ; Ewing, Ewoud ; Granqvist, Mathias ; Gyllenberg, Alexandra ; Aeinehband, Shahin ; Enoksson, Sara Lind ; Checa, Antonio ; Badam, Tejaswi V. S. ; Huang, Jesse ; Gomez-Cabrero, David ; Gustafsson, Mika ; Al Nimer, Faiez ; Wheelock, Craig E. ; Kockum, Ingrid ; Olsson, Tomas ; Jagodic, Maja ; Piehl, Fredrik
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3081-13, Article 3081
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Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming
Author / Creator:Jin, Jinmei ; Qiu, Shuiping ; Wang, Ping ; Liang, Xiaohui ; Huang, Fei ; Wu, Hui ; Zhang, Beibei ; Zhang, Weidong ; Tian, Xinhui ; Xu, Ren ; Shi, Hailian ; Wu, Xiaojun
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2019-08, Vol.38 (1), p.377-377, Article 377
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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome acti...
Author / Creator:Arlt, A ; Sebens, S ; Krebs, S ; Geismann, C ; Grossmann, M ; Kruse, M-L ; Schreiber, S ; Schäfer, H
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2013-10, Vol.32 (40), p.4825-4835
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Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists
Author / Creator:Bewley, Martin A. ; Budd, Richard C. ; Ryan, Eilise ; Cole, Joby ; Collini, Paul ; Marshall, Jennifer ; Kolsum, Umme ; Beech, Gussie ; Emes, Richard D. ; Tcherniaeva, Irina ; Berbers, Guy A. M. ; Walmsley, Sarah R. ; Donaldson, Gavin ; Wedzicha, Jadwiga A. ; Kilty, Iain ; Rumsey, William ; Sanchez, Yolanda ; Brightling, Christopher E. ; Donnelly, Louise E. ; Barnes, Peter J. ; Singh, Dave ; Whyte, Moira K. B. ; Dockrell, David H.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2018-09, Vol.198 (6), p.739-750
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ArticlesPeer ReviewedFull Text
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain
Author / Creator:Zhou, Ya-qun ; Liu, Dai-qiang ; Chen, Shu-ping ; Chen, Nan ; Sun, Jia ; Wang, Xiao-mei ; Cao, Fei ; Tian, Yu-ke ; Ye, Da-wei
Publisher:Singapore: Springer Singapore
Journal title:Acta pharmacologica Sinica, 2020-08, Vol.41 (8), p.1041-1048
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Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway
Author / Creator:Liu, Dequan ; Wang, Huilin ; Zhang, Yangang ; Zhang, Zhan
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2020, Vol.14, p.51-60
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A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer
Author / Creator:Choi, E-J ; Jung, B-J ; Lee, S-H ; Yoo, H-S ; Shin, E-A ; Ko, H-J ; Chang, S ; Kim, S-Y ; Jeon, S-M
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-09, Vol.36 (37), p.5285-5295
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APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy
Author / Creator:Du, Yu ; Zhou, Yu ; Yan, Xinyu ; Pan, Feiyan ; He, Lingfeng ; Guo, Zhigang ; Hu, Zhigang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2024-04, Vol.31 (4), p.431-446
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Resveratrol Alleviates Inflammatory Responses and Oxidative Stress in Rat Kidney Ischemia-Reperfusion Injury and H2O2-Induced NRK-52E Cells via the Nrf2/TLR4/NF-κB Pathway
Author / Creator:Li, Jiawei ; Li, Long ; Wang, Shuo ; Zhang, Chao ; Zheng, Long ; Jia, Yichen ; Xu, Ming ; Zhu, Tongyu ; Zhang, Yi ; Rong, Ruiming
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2018-01, Vol.45 (4), p.1677-1689
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ArticlesPeer ReviewedFull Text
Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage
Author / Creator:Sun, Xiaohui ; Wang, Qin ; Wang, Yan ; Du, Liqing ; Xu, Chang ; Liu, Qiang
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2016-07, Vol.17 (7), p.997-997
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Neuroprotection by Acetyl-11-Keto-β-Boswellic Acid, in Ischemic Brain Injury Involves the Nrf2/HO-1 defense Pathway
Author / Creator:Ding, Yi ; Chen, MinChun ; Wang, Min ; Wang, MingMing ; Zhang, Tiejun ; Park, Jongsun ; Zhu, YanRong ; Guo, Chao ; Jia, YanYan ; Li, YuWen ; Wen, AiDong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2014-11, Vol.4 (1), p.7002-7002, Article 7002
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Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway
Author / Creator:Chen, Xiuhuan ; Wan, Weiguo ; Guo, Yan ; Ye, Tianxin ; Fo, Yuhong ; Sun, Yazhou ; Qu, Chuan ; Yang, Bo ; Zhang, Cui
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2021-09, Vol.27 (1), p.100-100, Article 100
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ArticlesPeer ReviewedFull Text
Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2
Author / Creator:Wang, Yong ; Wang, Tingyu ; Wang, Daojuan ; Lu, Yadong ; Luo, Yongzheng ; Wang, Rong ; Pu, Wenyuan
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2019, Vol.2019 (2019), p.1-18
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Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner
Author / Creator:Huang, Xiao‑Ting ; Liu, Wei ; Zhou, Yong ; Hao, Cai‑Xia ; Zhou, Yan ; Zhang, Chen‑Yu ; Sun, Chen‑Chen ; Luo, Zi‑Qiang ; Tang, Si‑Yuan
Publisher:Athens: Spandidos Publications UK Ltd
Journal title:International journal of molecular medicine, 2019-12, Vol.44 (6), p.2213-2222
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Showing 1 to 20 of 158 results

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Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

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NRF2 regulates serine biosynthesis in non–small cell lung cancer

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Potential Applications of NRF2 Inhibitors in Cancer Therapy

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Luteolin Inhibits Breast Cancer Stemness and Enhances Chemosensitivity through the Nrf2-Mediated Pathway

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ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis

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Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer

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Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

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Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming

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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome acti...

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Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists

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Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain

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Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway

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A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer

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APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy

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Resveratrol Alleviates Inflammatory Responses and Oxidative Stress in Rat Kidney Ischemia-Reperfusion Injury and H2O2-Induced NRK-52E Cells via the Nrf2/TLR4/NF-κB Pathway

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Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage

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Neuroprotection by Acetyl-11-Keto-β-Boswellic Acid, in Ischemic Brain Injury Involves the Nrf2/HO-1 defense Pathway

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Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway

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Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2

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Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner

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