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692 results for Neoplasm+Proteins+-+chemistry

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ArticlesPeer ReviewedFull Text
Pore-forming activity and structural autoinhibition of the gasdermin family
Author / Creator:Ding, Jingjin ; Wang, Kun ; Liu, Wang ; She, Yang ; Sun, Qi ; Shi, Jianjin ; Sun, Hanzi ; Wang, Da-Cheng ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.111-116
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Author / Creator:Shi, Jianjin ; Zhao, Yue ; Wang, Kun ; Shi, Xuyan ; Wang, Yue ; Huang, Huanwei ; Zhuang, Yinghua ; Cai, Tao ; Wang, Fengchao ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-10, Vol.526 (7575), p.660-665
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Author / Creator:Liu, Xing ; Zhang, Zhibin ; Ruan, Jianbin ; Pan, Youdong ; Magupalli, Venkat Giri ; Wu, Hao ; Lieberman, Judy
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.153-158
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The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
Author / Creator:Malaker, Stacy A. ; Pedram, Kayvon ; Ferracane, Michael J. ; Bensing, Barbara A. ; Krishnan, Venkatesh ; Pett, Christian ; Yu, Jin ; Woods, Elliot C. ; Kramer, Jessica R. ; Westerlind, Ulrika ; Dorigo, Oliver ; Bertozzi, Carolyn R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7278-7287
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Cryo-EM structure of the gasdermin A3 membrane pore
Author / Creator:Ruan, Jianbin ; Xia, Shiyu ; Liu, Xing ; Lieberman, Judy ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-05, Vol.557 (7703), p.62-67
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Roles of METTL3 in cancer: mechanisms and therapeutic targeting
Author / Creator:Zeng, Chengwu ; Huang, Wanxu ; Li, Yangqiu ; Weng, Hengyou
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-08, Vol.13 (1), p.117-15, Article 117
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cGAS-STING, an important pathway in cancer immunotherapy
Author / Creator:Jiang, Minlin ; Chen, Peixin ; Wang, Lei ; Li, Wei ; Chen, Bin ; Liu, Yu ; Wang, Hao ; Zhao, Sha ; Ye, Lingyun ; He, Yayi ; Zhou, Caicun
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-06, Vol.13 (1), p.81-11, Article 81
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Structure of the human multidrug transporter ABCG2
Author / Creator:Taylor, Nicholas M. I. ; Manolaridis, Ioannis ; Jackson, Scott M. ; Kowal, Julia ; Stahlberg, Henning ; Locher, Kaspar P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7659), p.504-509
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EZH2: a novel target for cancer treatment
Author / Creator:Duan, Ran ; Du, Wenfang ; Guo, Weijian
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-07, Vol.13 (1), p.104-12, Article 104
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Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
Author / Creator:Sandstrom, Andrew ; Mitchell, Patrick S. ; Goers, Lisa ; Mu, Edward W. ; Lesser, Cammie F. ; Vance, Russell E.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6435), p.42-42
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Structural mechanisms for regulation of GSDMB pore-forming activity
Author / Creator:Zhong, Xiu ; Zeng, Huan ; Zhou, Zhiwei ; Su, Ya ; Cheng, Hang ; Hou, Yanjie ; She, Yang ; Feng, Na ; Wang, Jia ; Shao, Feng ; Ding, Jingjin
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-04, Vol.616 (7957), p.598-605
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It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation
Author / Creator:Wiedner, Hannah J. ; Giudice, Jimena
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-06, Vol.28 (6), p.465-473
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Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling
Author / Creator:McNally, Kerrie E. ; Faulkner, Rebecca ; Steinberg, Florian ; Gallon, Matthew ; Ghai, Rajesh ; Pim, David ; Langton, Paul ; Pearson, Neil ; Danson, Chris M. ; Nägele, Heike ; Morris, Lindsey L. ; Singla, Amika ; Overlee, Brittany L. ; Heesom, Kate J. ; Sessions, Richard ; Banks, Lawrence ; Collins, Brett M. ; Berger, Imre ; Billadeau, Daniel D. ; Burstein, Ezra ; Cullen, Peter J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2017-10, Vol.19 (10), p.1214-1225
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ArticlesPeer ReviewedFull Text
Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor
Author / Creator:Yang, Jie ; Liu, Zhonghua ; Wang, Chuanping ; Yang, Rui ; Rathkey, Joseph K. ; Pinkard, Otis W. ; Shi, Wuxian ; Chen, Yinghua ; Dubyak, George R. ; Abbott, Derek W. ; Xiao, Tsan Sam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6792-6797
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ArticlesPeer ReviewedFull Text
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein
Author / Creator:Chao, Kinlin L. ; Kulakova, Liudmila ; Herzberg, Osnat
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1128-E1137
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Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states
Author / Creator:Manolaridis, Ioannis ; Jackson, Scott M. ; Taylor, Nicholas M. I. ; Kowal, Julia ; Stahlberg, Henning ; Locher, Kaspar P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-11, Vol.563 (7731), p.426-430
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ArticlesPeer ReviewedFull Text
X-ray structure of a calcium-activated TMEM16 lipid scramblase
Author / Creator:Brunner, Janine D. ; Lim, Novandy K. ; Schenck, Stephan ; Duerst, Alessia ; Dutzler, Raimund
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-12, Vol.516 (7530), p.207-212
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Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology
Author / Creator:Hallberg, Bengt ; Palmer, Ruth H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2013-10, Vol.13 (10), p.685-700
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Krüppel-like factors in cancer
Author / Creator:Tetreault, Marie-Pier ; Yang, Yizeng ; Katz, Jonathan P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2013-10, Vol.13 (10), p.701-713
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ArticlesPeer ReviewedFull Text
VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy
Author / Creator:Huang, Xing ; Zhang, Xiaozhen ; Li, Enliang ; Zhang, Gang ; Wang, Xun ; Tang, Tianyu ; Bai, Xueli ; Liang, Tingbo
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-06, Vol.13 (1), p.83-83, Article 83
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Showing 1 to 20 of 692 results

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Pore-forming activity and structural autoinhibition of the gasdermin family

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

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Cryo-EM structure of the gasdermin A3 membrane pore

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Roles of METTL3 in cancer: mechanisms and therapeutic targeting

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cGAS-STING, an important pathway in cancer immunotherapy

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Structure of the human multidrug transporter ABCG2

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EZH2: a novel target for cancer treatment

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Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes

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Structural mechanisms for regulation of GSDMB pore-forming activity

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It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation

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Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

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Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

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Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein

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Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

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X-ray structure of a calcium-activated TMEM16 lipid scramblase

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Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology

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Krüppel-like factors in cancer

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VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy

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