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103 results for Neurofibromatosis+1+-+metabolism

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ArticlesPeer ReviewedFull Text
Selumetinib: First Approval
Author / Creator:Markham, Anthony ; Keam, Susan J.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2020-06, Vol.80 (9), p.931-937
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Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
Author / Creator:Guo, Xiaofan ; Pan, Yuan ; Xiong, Min ; Sanapala, Shilpa ; Anastasaki, Corina ; Cobb, Olivia ; Dahiya, Sonika ; Gutmann, David H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2177-2177, Article 2177
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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/– mice
Author / Creator:Park, Su Jung ; Lukkes, Jodi L. ; Chan, Ka-Kui ; Drozd, Hayley P. ; Burgin, Callie B. ; Qian, Shaomin ; Sullivan, Morgan McKenzie ; Guevara, Cesar Gabriel ; Cunningham, Nolen ; Arenas, Stephanie ; Collins, Makenna A. ; Zucker, Jacob ; Won, JinHee ; Smith, Abbi ; Jiang, Li ; Mitchell, Dana K. ; Rhodes, Steven D. ; Angus, Steven P. ; Clapp, D. Wade
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2025-07, Vol.135 (13)
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Neurofibromin and suppression of tumorigenesis: beyond the GAP
Author / Creator:Mo, Juan ; Moye, Stefanie L ; McKay, Renee M ; Le, Lu Q
Publisher:New York: Nature Publishing Group
Journal title:Oncogene, 2022-02, Vol.41 (9), p.1235-1251
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The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas
Author / Creator:Pemov, A ; Li, H ; Patidar, R ; Hansen, N F ; Sindiri, S ; Hartley, S W ; Wei, J S ; Elkahloun, A ; Chandrasekharappa, S C ; Boland, J F ; Bass, S ; Mullikin, J C ; Khan, J ; Widemann, B C ; Wallace, M R ; Stewart, D R
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-06, Vol.36 (22), p.3168-3177
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ArticlesPeer ReviewedFull Text
Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia
Author / Creator:Chatterjee, Jit ; Sanapala, Shilpa ; Cobb, Olivia ; Bewley, Alice ; Goldstein, Andrea K. ; Cordell, Elizabeth ; Ge, Xia ; Garbow, Joel R. ; Holtzman, Michael J. ; Gutmann, David H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7122-7122, Article 7122
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Tumorigenesis in neurofibromatosis type 1: role of the microenvironment
Author / Creator:Jiang, Chunhui ; McKay, Renee M. ; Le, Lu Q.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-09, Vol.40 (39), p.5781-5787
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Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance
Author / Creator:Vasudevan, Harish N. ; Payne, Emily ; Delley, Cyrille L. ; John Liu, S. ; Mirchia, Kanish ; Sale, Matthew J. ; Lastella, Sydney ; Nunez, Maria Sacconi ; Lucas, Calixto-Hope G. ; Eaton, Charlotte D. ; Casey-Clyde, Tim ; Magill, Stephen T. ; Chen, William C. ; Braunstein, Steve E. ; Perry, Arie ; Jacques, Line ; Reddy, Alyssa T. ; Pekmezci, Melike ; Abate, Adam R. ; McCormick, Frank ; Raleigh, David R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.477-13, Article 477
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STING activation reprograms the microenvironment to sensitize NF1-related malignant peripheral nerve sheath tumors for immunotherapy
Author / Creator:Somatilaka, Bandarigoda N. ; Madana, Laasya ; Sadek, Ali ; Chen, Zhiguo ; Chandrasekaran, Sanjay ; McKay, Renee M. ; Le, Lu Q.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-05, Vol.134 (10), p.1-13
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ArticlesPeer ReviewedFull Text
Dietary intervention rescues a bone porosity phenotype in a murine model of Neurofibromatosis Type 1 (NF1)
Author / Creator:O’Donohue, Alexandra K. ; Li, Xiaoying C. ; Lee, Lucinda R. ; Vasiljevski, Emily R. ; Little, David G. ; Munns, Craig F. ; Schindeler, Aaron
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-06, Vol.19 (6), p.e0304778
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ArticlesPeer ReviewedFull Text
Icariin Promotes Osteogenic Differentiation in a Cell Model with NF1 Gene Knockout by Activating the cAMP/PKA/CREB Pathway
Author / Creator:Chen, Meng ; Lu, Lianhua ; Cheng, Dong ; Zhang, Jing ; Liu, Xinyong ; Zhang, Jianli ; Zhang, Tianliang
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-06, Vol.28 (13), p.5128
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ArticlesPeer ReviewedFull Text
STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma
Author / Creator:Fletcher, Jonathan S. ; Springer, Mitchell G. ; Choi, Kwangmin ; Jousma, Edwin ; Rizvi, Tilat A. ; Dombi, Eva ; Kim, Mi-Ok ; Wu, Jianqiang ; Ratner, Nancy
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2019-04, Vol.38 (15), p.2876-2884
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ArticlesPeer ReviewedFull Text
Electrical stimulation of Schwann cells on electrospun hyaluronic acid carbon nanotube fibers
Author / Creator:Senanayake, Judy ; Mattingly, Raymond R. ; Sundararaghavan, Harini G.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-08, Vol.19 (8), p.e0308207
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ArticlesPeer ReviewedFull Text
Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas
Author / Creator:Dougherty, Jacquelyn ; Harvey, Kyra ; Liou, Angela ; Labella, Katherine ; Moran, Deborah ; Brosius, Stephanie ; De Raedt, Thomas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2023-02, Vol.18 (2), p.e0277305-e0277305
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ArticlesPeer ReviewedFull Text
Breast cancer in neurofibromatosis 1: survival and risk of contralateral breast cancer in a five country cohort study
Author / Creator:Evans, D. Gareth R. ; Kallionpää, Roope A. ; Clementi, Maurizio ; Trevisson, Eva ; Mautner, Victor-Felix ; Howell, Sacha J. ; Lewis, Lauren ; Zehou, Ouidad ; Peltonen, Sirkku ; Brunello, Antonella ; Harkness, Elaine F. ; Wolkenstein, Pierre ; Peltonen, Juha
Publisher:New York: Nature Publishing Group US
Journal title:Genetics in medicine, 2020-02, Vol.22 (2), p.398-406
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ArticlesPeer ReviewedFull Text
Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review
Author / Creator:Barreto-Duarte, Beatriz ; Andrade-Gomes, Fabiana H. ; Arriaga, María B. ; Araújo-Pereira, Mariana ; Cubillos-Angulo, Juan Manuel ; Andrade, Bruno B.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-01, Vol.16 (1), p.e0241096-e0241096
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Individual Response to Radiation of Individuals with Neurofibromatosis Type I: Role of the ATM Protein and Influence of Statins and Bisphosphonates
Author / Creator:Combemale Patrick ; Sonzogni Laurène ; Devic Clément ; Bencokova Zuzana ; Ferlazzo, Mélanie Lydia ; Granzotto Adeline ; Burlet Steven Franck ; Pinson Stéphane ; Amini-Adle Mona ; Al-Choboq, Joëlle ; Bodgi Larry ; Bourguignon, Michel ; Balosso Jacques ; Jean-Thomas, Bachelet ; ay, Nicolas
Publisher:Totowa: Springer Nature B.V
Journal title:Molecular neurobiology, 2022-01, Vol.59 (1), p.556-573
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Inhibition of autophagy as a novel treatment for neurofibromatosis type 1 tumors
Author / Creator:Stevens, Megan ; Wang, Yuanli ; Bouley, Stephanie J. ; Mandigo, Torrey R. ; Sharma, Aditi ; Sengupta, Sonali ; Housden, Amy ; Perrimon, Norbert ; Walker, James A. ; Housden, Benjamin E.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2025-03, Vol.19 (3), p.825-851
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Interferon-Induced Transmembrane Protein 1 (IFITM1) Is Downregulated in Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors
Author / Creator:Park, Gun-Hoo ; Park, Eunkuk ; Lee, Su-Jin ; Lim, Kyubin ; Kim, Jeonghyun ; Park, Jun Eun ; Jeong, Seon-Yong
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-09, Vol.25 (17), p.9265
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ArticlesPeer ReviewedFull Text
The NF1 Tumor Suppressor Critically Regulates TSC2 and mTOR
Author / Creator:Johannessen, Cory M. ; Reczek, Elizabeth E. ; James, Marianne F. ; Brems, Hilde ; Legius, Eric ; Cichowski, Karen ; Cantley, Lewis C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (24), p.8573-8578
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Showing 1 to 20 of 103 results

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Selumetinib: First Approval

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Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth

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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/– mice

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Neurofibromin and suppression of tumorigenesis: beyond the GAP

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The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas

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Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

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Tumorigenesis in neurofibromatosis type 1: role of the microenvironment

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Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance

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STING activation reprograms the microenvironment to sensitize NF1-related malignant peripheral nerve sheath tumors for immunotherapy

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Dietary intervention rescues a bone porosity phenotype in a murine model of Neurofibromatosis Type 1 (NF1)

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Icariin Promotes Osteogenic Differentiation in a Cell Model with NF1 Gene Knockout by Activating the cAMP/PKA/CREB Pathway

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STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma

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Electrical stimulation of Schwann cells on electrospun hyaluronic acid carbon nanotube fibers

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Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas

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Breast cancer in neurofibromatosis 1: survival and risk of contralateral breast cancer in a five country cohort study

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Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review

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Individual Response to Radiation of Individuals with Neurofibromatosis Type I: Role of the ATM Protein and Influence of Statins and Bisphosphonates

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Inhibition of autophagy as a novel treatment for neurofibromatosis type 1 tumors

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Interferon-Induced Transmembrane Protein 1 (IFITM1) Is Downregulated in Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

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The NF1 Tumor Suppressor Critically Regulates TSC2 and mTOR

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