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Predicting immune checkpoint inhibitor response in urothelial carcinoma: another step in personalised medicine?
Author / Creator:Niegisch, Günter
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-02, Vol.122 (4), p.453-454
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New synergistic combination therapy approaches with HDAC inhibitor quisinostat, cisplatin or PARP inhibitor talazoparib for urothelial carcinoma
Author / Creator:Meneceur, Sarah ; De Vos, Caroline E. ; Petzsch, Patrick ; Köhrer, Karl ; Niegisch, Günter ; Hoffmann, Michèle J.
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2024-05, Vol.28 (9), p.e18342-n/a
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Prodigiosin Sensitizes Sensitive and Resistant Urothelial Carcinoma Cells to Cisplatin Treatment
Author / Creator:Berning, Lena ; Schlütermann, David ; Friedrich, Annabelle ; Berleth, Niklas ; Sun, Yadong ; Wu, Wenxian ; Mendiburo, María José ; Deitersen, Jana ; Brass, Hannah U. C. ; Skowron, Margaretha A. ; Hoffmann, Michèle J. ; Niegisch, Günter ; Pietruszka, Jörg ; Stork, Björn
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-02, Vol.26 (5), p.1294
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Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma
Author / Creator:Droop, Johanna ; Szarvas, Tibor ; Schulz, Wolfgang A. ; Niedworok, Christian ; Niegisch, Günter ; Scheckenbach, Kathrin ; Hoffmann, Michèle J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-04, Vol.12 (4), p.e0176287-e0176287
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Tailored immunotherapy approach with nivolumab with or without ipilimumab in patients with advanced transitional cell carcinoma after platinum-based chemotherapy (TITAN-TCC): a multicentre, single-arm...
Author / Creator:Grimm, Marc-Oliver, Prof ; Grün, Christine Barbara, MD ; Niegisch, Günter, Prof ; Pichler, Martin, Prof ; Roghmann, Florian, Prof ; Schmitz-Dräger, Bernd, Prof ; Baretton, Gustavo, Prof ; Schmitz, Marc, Prof ; Bolenz, Christian, Prof ; Foller, Susan, MD ; Leucht, Katharina, PhD ; Schumacher, Ulrike, PhD ; Schostak, Martin, Prof ; Meran, Johannes, Prof ; Loidl, Wolfgang, Prof ; Zengerling, Friedemann, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-04, Vol.24 (4), p.347-359
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Cognitive function in patients undergoing cystectomy for bladder cancer – results from a prospective observational study
Author / Creator:Grunewald, Camilla M. ; Feldmeier, Vera ; Supprian, Tillmann ; Albers, Peter ; Giessing, Markus ; Niegisch, Günter
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in urology, 2022-03, Vol.14, p.17562872221087660-17562872221087660
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Efficacy of immune checkpoint inhibitor therapy for advanced urothelial carcinoma in real-life clinical practice: results of a multicentric, retrospective study
Author / Creator:Váradi, Melinda ; Horváth, Orsolya ; Módos, Orsolya ; Fazekas, Tamás ; Grunewald, Camilla M. ; Niegisch, Günter ; Krafft, Ulrich ; Grünwald, Viktor ; Hadaschik, Boris ; Olah, Csilla ; Maráz, Anikó ; Furka, Andrea ; Szűcs, Miklós ; Nyirády, Péter ; Szarvas, Tibor
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-10, Vol.13 (1), p.17378-17378, Article 17378
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Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells
Author / Creator:Hoffmann, Michèle J. ; Meneceur, Sarah ; Hommel, Katrin ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2021-02, Vol.12 (2), p.260
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The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells
Author / Creator:Heubach, Judith ; Monsior, Juliana ; Deenen, René ; Niegisch, Günter ; Szarvas, Tibor ; Niedworok, Christian ; Schulz, Wolfgang Arthur ; Hoffmann, Michèle Janine
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2015-05, Vol.14 (1), p.108-108, Article 108
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Many Different LINE-1 Retroelements Are Activated in Bladder Cancer
Author / Creator:Whongsiri, Patcharawalai ; Goering, Wolfgang ; Lautwein, Tobias ; Hader, Christiane ; Niegisch, Günter ; Köhrer, Karl ; Hoffmann, Michèle J. ; Schulz, Wolfgang A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-12, Vol.21 (24), p.9433
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Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation
Author / Creator:Morsch, Ronja ; Rose, Michael ; Maurer, Angela ; Cassataro, Maria Angela ; Braunschweig, Till ; Knüchel, Ruth ; Vögeli, Thomas-Alexander ; Ecke, Thorsten ; Eckstein, Markus ; Weyerer, Veronika ; Esposito, Irene ; Ackermann, Maximilian ; Niegisch, Günter ; Gaisa, Nadine T.
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2020-03, Vol.20 (1), p.230-230, Article 230
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Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines
Author / Creator:Pinkerneil, Maria ; Hoffmann, Michèle J. ; Kohlhof, Hella ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2016-12, Vol.11 (6), p.783-798
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ArticlesPeer ReviewedFull Text
Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression
Author / Creator:Jaguva Vasudevan, Ananda Ayyappan ; Hoffmann, Michèle J. ; Poschmann, Gereon ; Petzsch, Patrick ; Wiek, Constanze ; Stühler, Kai ; Köhrer, Karl ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:London: Nature Publishing Group UK
Journal title:Scientific data, 2022-05, Vol.9 (1), p.240-240, Article 240
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Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine
Author / Creator:Isono, Makoto ; Hoffmann, Michèle J. ; Pinkerneil, Maria ; Sato, Akinori ; Michaelis, Martin ; Cinatl, Jindrich ; Niegisch, Günter ; Schulz, Wolfgang A.
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2017-01, Vol.36 (1), p.1-1, Article 1
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Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1
Author / Creator:Erichsen, Lars ; Seifert, Hans-Helge ; Schulz, Wolfgang A. ; Hoffmann, Michèle J. ; Niegisch, Günter ; Araúzo-Bravo, Marcos J. ; Bendhack, Marcelo L. ; Poyet, Cedric ; Hermanns, Thomas ; Beermann, Agnes ; Hassan, Mohamed ; Theis, Lisa ; Mahmood, Wardah ; Santourlidis, Simeon
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-03, Vol.10 (1), p.3808, Article 3808
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ArticlesPeer ReviewedFull Text
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines
Author / Creator:Skowron, Margaretha A. ; Petzsch, Patrick ; Hardt, Karin ; Wagner, Nicholas ; Beier, Manfred ; Stepanow, Stefanie ; Drechsler, Matthias ; Rieder, Harald ; Köhrer, Karl ; Niegisch, Günter ; Hoffmann, Michèle J. ; Schulz, Wolfgang A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.14476-14, Article 14476
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Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment
Author / Creator:Thy, Sophia ; Hommel, Alexandra ; Meneceur, Sarah ; Bartkowiak, Anna L. ; Schulz, Wolfgang A. ; Niegisch, Günter ; Hoffmann, Michèle J.
Publisher:Switzerland: MDPI
Journal title:Cancers, 2021-03, Vol.13 (6), p.1376
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Effects of novel HDAC inhibitors on urothelial carcinoma cells
Author / Creator:Kaletsch, Aline ; Pinkerneil, Maria ; Hoffmann, Michèle J. ; Jaguva Vasudevan, Ananda A. ; Wang, Chenyin ; Hansen, Finn K. ; Wiek, Constanze ; Hanenberg, Helmut ; Gertzen, Christoph ; Gohlke, Holger ; Kassack, Matthias U. ; Kurz, Thomas ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2018-07, Vol.10 (1), p.100-100, Article 100
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CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma
Author / Creator:Klümper, Niklas ; Ralser, Damian J ; Zarbl, Romina ; Schlack, Katrin ; Schrader, Andres Jan ; Rehlinghaus, Marc ; Hoffmann, Michèle J ; Niegisch, Günter ; Uhlig, Annemarie ; Trojan, Lutz ; Steinestel, Julie ; Steinestel, Konrad ; Wirtz, Ralph M ; Sikic, Danijel ; Eckstein, Markus ; Kristiansen, Glen ; Toma, Marieta ; Hölzel, Michael ; Ritter, Manuel ; Strieth, Sebastian ; Ellinger, Jörg ; Dietrich, Dimo
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e002949
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Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines
Author / Creator:Hölscher, Alexander S. ; Schulz, Wolfgang A. ; Pinkerneil, Maria ; Niegisch, Günter ; Hoffmann, Michèle J.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2018-01, Vol.10 (1), p.1-14, Article 1
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Showing 1 to 20 of 55 results

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Predicting immune checkpoint inhibitor response in urothelial carcinoma: another step in personalised medicine?

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New synergistic combination therapy approaches with HDAC inhibitor quisinostat, cisplatin or PARP inhibitor talazoparib for urothelial carcinoma

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Prodigiosin Sensitizes Sensitive and Resistant Urothelial Carcinoma Cells to Cisplatin Treatment

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Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma

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Tailored immunotherapy approach with nivolumab with or without ipilimumab in patients with advanced transitional cell carcinoma after platinum-based chemotherapy (TITAN-TCC): a multicentre, single-arm...

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Cognitive function in patients undergoing cystectomy for bladder cancer – results from a prospective observational study

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Efficacy of immune checkpoint inhibitor therapy for advanced urothelial carcinoma in real-life clinical practice: results of a multicentric, retrospective study

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Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells

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The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells

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Many Different LINE-1 Retroelements Are Activated in Bladder Cancer

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Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation

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Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines

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Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression

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Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine

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Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1

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Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines

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Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment

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Effects of novel HDAC inhibitors on urothelial carcinoma cells

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CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma

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Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines

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