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ArticlesPeer ReviewedFull Text
MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis
Author / Creator:Oka, Sugako ; Leon, Julio ; Sakumi, Kunihiko ; Abolhassani, Nona ; Sheng, Zijing ; Tsuchimoto, Daisuke ; LaFerla, Frank M. ; Nakabeppu, Yusaku
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-03, Vol.11 (1), p.5819-5819, Article 5819
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ArticlesPeer ReviewedFull Text
DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis
Author / Creator:Oka, Sugako ; Nakabeppu, Yusaku
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 2011-04, Vol.102 (4), p.677-682
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Suppression of stress granule formation is a vulnerability imposed by mutant p53
Author / Creator:Thoenen, Elizabeth ; Ranjan, Atul ; Parrales, Alejandro ; Nishikawa, Shigeto ; Dixon, Dan A. ; Oka, Sugako ; Iwakuma, Tomoo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2365-17, Article 2365
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8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair
Author / Creator:Sheng, Zijing ; Oka, Sugako ; Tsuchimoto, Daisuke ; Abolhassani, Nona ; Nomaru, Hiroko ; Sakumi, Kunihiko ; Yamada, Hidetaka ; Nakabeppu, Yusaku
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-12, Vol.122 (12), p.4344-4361
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ArticlesPeer ReviewedFull Text
Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease
Author / Creator:Oka, Sugako ; Leon, Julio ; Sakumi, Kunihiko ; Ide, Tomomi ; Kang, Dongchon ; LaFerla, Frank M. ; Nakabeppu, Yusaku
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-11, Vol.6 (1), p.37889-37889, Article 37889
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ArticlesPeer ReviewedFull Text
Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs
Author / Creator:Oka, Sugako ; Ohno, Mizuki ; Tsuchimoto, Daisuke ; Sakumi, Kunihiko ; Furuichi, Masato ; Nakabeppu, Yusaku
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2008-01, Vol.27 (2), p.421-432
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ArticlesPeer ReviewedFull Text
Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis
Author / Creator:Yogianti, Flandiana ; Kunisada, Makoto ; Nakano, Eiji ; Ono, Ryusuke ; Sakumi, Kunihiko ; Oka, Sugako ; Nakabeppu, Yusaku ; Nishigori, Chikako
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-10, Vol.134 (10), p.2610-2619
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ArticlesPeer ReviewedFull Text
Endogenous ROS production in early differentiation state suppresses endoderm differentiation via transient FOXC1 expression
Author / Creator:Oka, Sugako ; Tsuzuki, Teruhisa ; Hidaka, Masumi ; Ohno, Mizuki ; Nakatsu, Yoshimichi ; Sekiguchi, Mutsuo
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2022-04, Vol.8 (1), p.150-150, Article 150
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ArticlesPeer ReviewedFull Text
Nature of nontargeted radiation effects observed during fractionated irradiation-induced thymic lymphomagenesis in mice
Author / Creator:Tsuji, Hideo ; Ishii-Ohba, Hiroko ; Shiomi, Tadahiro ; Shiomi, Naoko ; Katsube, Takanori ; Mori, Masahiko ; Nenoi, Mitsuru ; Ohno, Mizuki ; Yoshimura, Daisuke ; Oka, Sugako ; Nakabeppu, Yusaku ; Tatsumi, Kouichi ; Muto, Masahiro ; Sado, Toshihiko
Publisher:England: Oxford University Press
Journal title:Journal of radiation research, 2013-05, Vol.54 (3), p.453-466
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ArticlesPeer ReviewedFull Text
8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions
Author / Creator:Leon, Julio ; Sakumi, Kunihiko ; Castillo, Erika ; Sheng, Zijing ; Oka, Sugako ; Nakabeppu, Yusaku
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-02, Vol.6 (1), p.22086-22086, Article 22086
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ArticlesPeer ReviewedFull Text
Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions
Author / Creator:Leon, Julio ; Sakumi, Kunihiko ; Castillo, Erika ; Sheng, Zijing ; Oka, Sugako ; Nakabeppu, Yusaku
Publisher:England: Nature Publishing Group
Journal title:Scientific reports, 2016-04, Vol.6, p.24696-24696
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ArticlesPeer ReviewedFull Text
Correction: Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions
Author / Creator:Leon, Julio ; Sakumi, Kunihiko ; Castillo, Erika ; Sheng, Zijing ; Oka, Sugako ; Nakabeppu, Yusaku
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-04, Vol.6 (1), Article 24696
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ArticlesPeer ReviewedFull Text
Prominent bifid T waves observed in the QT prolongation caused by complete atrioventricular blockade in a hypokalemic diabetic patient
Author / Creator:Oka-Manabe, Sugako ; Maruyama, Toru ; Urae, Ryuji ; Amamoto, Toshiaki ; Niho, Yoshiyuki
Publisher:Orlando, FL: Elsevier Inc
Journal title:Journal of electrocardiology, 1999-07, Vol.32 (3), p.289-292
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MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis

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DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis

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Suppression of stress granule formation is a vulnerability imposed by mutant p53

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8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair

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Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease

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Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

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Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis

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Endogenous ROS production in early differentiation state suppresses endoderm differentiation via transient FOXC1 expression

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Nature of nontargeted radiation effects observed during fractionated irradiation-induced thymic lymphomagenesis in mice

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8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

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Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

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Correction: Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

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Prominent bifid T waves observed in the QT prolongation caused by complete atrioventricular blockade in a hypokalemic diabetic patient

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