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Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial
Author / Creator:Nordlinger, Bernard, Prof ; Sorbye, Halfdan, MD ; Glimelius, Bengt, Prof ; Poston, Graeme J, MD ; Schlag, Peter M, Prof ; Rougier, Philippe, Prof ; Bechstein, Wolf O, Prof ; Primrose, John N, Prof ; Walpole, Euan T, MD ; Finch-Jones, Meg, MD ; Jaeck, Daniel, MD ; Mirza, Darius, MD ; Parks, Rowan W, MD ; Collette, Laurence, PhD ; Praet, Michel, ScD ; Bethe, Ullrich, MD ; Van Cutsem, Eric, MD ; Scheithauer, Werner, MD ; Gruenberger, Thomas, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2008-03, Vol.371 (9617), p.1007-1016
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FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis
Author / Creator:Suker, Mustafa, MD ; Beumer, Berend R ; Sadot, Eran, MD ; Marthey, Lysiane, MD ; Faris, Jason E, MD ; Mellon, Eric A, MD ; El-Rayes, Bassel F, Prof ; Wang-Gillam, Andrea, MD ; Lacy, Jill, Prof ; Hosein, Peter J, MD ; Moorcraft, Sing Yu, MD ; Conroy, Thierry, Prof ; Hohla, Florian, MD ; Allen, Peter, MD ; Taieb, Julien, Prof ; Hong, Theodore S, MD ; Shridhar, Ravi, MD ; Chau, Ian, MD ; van Eijck, Casper H, Prof ; Koerkamp, Bas Groot, Dr
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.801-810
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Duration of Adjuvant Chemotherapy for Stage III Colon Cancer
Author / Creator:Grothey, Axel ; Sobrero, Alberto F ; Shields, Anthony F ; Yoshino, Takayuki ; Paul, James ; Taieb, Julien ; Souglakos, John ; Shi, Qian ; Kerr, Rachel ; Labianca, Roberto ; Meyerhardt, Jeffrey A ; Vernerey, Dewi ; Yamanaka, Takeharu ; Boukovinas, Ioannis ; Meyers, Jeffrey P ; Renfro, Lindsay A ; Niedzwiecki, Donna ; Watanabe, Toshiaki ; Torri, Valter ; Saunders, Mark ; Sargent, Daniel J ; Andre, Thierry ; Iveson, Timothy
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-03, Vol.378 (13), p.1177-1188
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Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials
Author / Creator:André, Thierry, Prof ; Meyerhardt, Jeffrey, Prof ; Iveson, Timothy, Prof ; Sobrero, Alberto, Prof ; Yoshino, Takayuki, Prof ; Souglakos, Ioannis, MD ; Grothey, Axel, Prof ; Niedzwiecki, Donna, Prof ; Saunders, Mark, Prof ; Labianca, Roberto, Prof ; Yamanaka, Takeharu, Prof ; Boukovinas, Ioannis, MD ; Vernerey, Dewi, PhD ; Meyers, Jeffrey, BS ; Harkin, Andrea, BA ; Torri, Valter, MD ; Oki, Eiji, MD ; Georgoulias, Vassilis, Prof ; Taieb, Julien, Prof ; Shields, Anthony, Prof ; Shi, Qian, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-12, Vol.21 (12), p.1620-1629
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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label,...
Author / Creator:Nywening, Timothy M, MD ; Wang-Gillam, Andrea, MD ; Sanford, Dominic E, MD ; Belt, Brian A, MA ; Panni, Roheena Z, MD ; Cusworth, Brian M, BA ; Toriola, Adetunji T, MD ; Nieman, Rebecca K, MS ; Worley, Lori A, BS ; Yano, Motoyo, MD ; Fowler, Kathryn J, MD ; Lockhart, A Craig, MD ; Suresh, Rama, MD ; Tan, Benjamin R, MD ; Lim, Kian-Huat, MD ; Fields, Ryan C, MD ; Strasberg, Steven M, Prof ; Hawkins, William G, Prof ; DeNardo, David G, PhD ; Goedegebuure, S Peter, PhD ; Linehan, David C, Dr Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-05, Vol.17 (5), p.651-662
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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...
Author / Creator:Tabernero, Josep, Dr ; Yoshino, Takayuki, MD ; Cohn, Allen Lee, MD ; Obermannova, Radka, MD ; Bodoky, Gyorgy, Prof ; Garcia-Carbonero, Rocio, MD ; Ciuleanu, Tudor-Eliade, Prof ; Portnoy, David C, MD ; Van Cutsem, Eric, Prof ; Grothey, Axel, MD ; Prausová, Jana, MD ; Garcia-Alfonso, Pilar, PhD ; Yamazaki, Kentaro, MD ; Clingan, Philip R, Prof ; Lonardi, Sara, MD ; Kim, Tae Won, Prof ; Simms, Lorinda, MS ; Chang, Shao-Chun, PhD ; Nasroulah, Federico, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.499-508
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Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): 5-year follow-up of an open-label, randomised phase 3 trial
Author / Creator:Noh, Sung Hoon, Prof ; Park, Sook Ryun, MD ; Yang, Han-Kwang, Prof ; Chung, Hyun Cheol, Prof ; Chung, Ik-Joo, Prof ; Kim, Sang-Woon, Prof ; Kim, Hyung-Ho, MD ; Choi, Jin-Hyuk, Prof ; Kim, Hoon-Kyo, Prof ; Yu, Wansik, Prof ; Lee, Jong Inn, MD ; Shin, Dong Bok, Prof ; Ji, Jiafu, Prof ; Chen, Jen-Shi, MD ; Lim, Yunni, MS ; Ha, Stella, MS ; Bang, Yung-Jue, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-11, Vol.15 (12), p.1389-1396
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Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial
Author / Creator:Garcia-Aguilar, Julio, Prof ; Chow, Oliver S, MD ; Smith, David D, Prof ; Marcet, Jorge E, Prof ; Cataldo, Peter A, Prof ; Varma, Madhulika G, Prof ; Kumar, Anjali S, MD ; Oommen, Samuel, MD ; Coutsoftides, Theodore, MD ; Hunt, Steven R, MD ; Stamos, Michael J, Prof ; Ternent, Charles A, MD ; Herzig, Daniel O, MD ; Fichera, Alessandro, Prof ; Polite, Blase N, MD ; Dietz, David W, MD ; Patil, Sujata, PhD ; Avila, Karin, MSc
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-08, Vol.16 (8), p.957-966
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Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicen...
Author / Creator:Rödel, Claus, Prof ; Graeven, Ullrich, MD ; Fietkau, Rainer, Prof ; Hohenberger, Werner, Prof ; Hothorn, Torsten, Prof ; Arnold, Dirk, Prof ; Hofheinz, Ralf-Dieter, Prof ; Ghadimi, Michael, Prof ; Wolff, Hendrik A, MD ; Lang-Welzenbach, Marga, MSc ; Raab, Hans-Rudolf, Prof ; Wittekind, Christian, Prof ; Ströbel, Philipp, Prof ; Staib, Ludger, Prof ; Wilhelm, Martin, Prof ; Grabenbauer, Gerhard G, Prof ; Hoffmanns, Hans, MD ; Lindemann, Fritz, MD ; Schlenska-Lange, Anke, MD ; Folprecht, Gunnar, Prof ; Sauer, Rolf, Prof ; Liersch, Torsten, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-08, Vol.16 (8), p.979-989
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ArticlesPeer ReviewedFull Text
Pancreatic cancer
Author / Creator:Kamisawa, Terumi, Dr ; Wood, Laura D, MD ; Itoi, Takao, MD ; Takaori, Kyoichi, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-07, Vol.388 (10039), p.73-85
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Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-0...
Author / Creator:Rödel, Claus, Prof ; Liersch, Torsten, MD ; Becker, Heinz, Prof ; Fietkau, Rainer, Prof ; Hohenberger, Werner, Prof ; Hothorn, Torsten, Prof ; Graeven, Ullrich, MD ; Arnold, Dirk, Prof ; Lang-Welzenbach, Marga, MSc ; Raab, Hans-Rudolf, Prof ; Sülberg, Heiko, MSc ; Wittekind, Christian, Prof ; Potapov, Sergej, MSc ; Staib, Ludger, Prof ; Hess, Clemens, Prof ; Weigang-Köhler, Karin, MD ; Grabenbauer, Gerhard G, Prof ; Hoffmanns, Hans, MD ; Lindemann, Fritz, MD ; Schlenska-Lange, Anke, MD ; Folprecht, Gunnar, MD ; Sauer, Rolf, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-07, Vol.13 (7), p.679-687
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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...
Author / Creator:Cremolini, Chiara, MD ; Loupakis, Fotios, PhD ; Antoniotti, Carlotta, MD ; Lupi, Cristiana, BSc ; Sensi, Elisa, PhD ; Lonardi, Sara, MD ; Mezi, Silvia, MD ; Tomasello, Gianluca, MD ; Ronzoni, Monica, MD ; Zaniboni, Alberto, MD ; Tonini, Giuseppe, Prof ; Carlomagno, Chiara, PhD ; Allegrini, Giacomo, MD ; Chiara, Silvana, MD ; D'Amico, Mauro, MD ; Granetto, Cristina, MD ; Cazzaniga, Marina, MD ; Boni, Luca, MD ; Fontanini, Gabriella, Prof ; Falcone, Alfredo, Prof
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1306-1315
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ArticlesPeer ReviewedFull Text
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
Author / Creator:Nordlinger, Bernard, Prof ; Sorbye, Halfdan, Prof ; Glimelius, Bengt, Prof ; Poston, Graeme J, Prof ; Schlag, Peter M, Prof ; Rougier, Philippe, Prof ; Bechstein, Wolf O, Prof ; Primrose, John N, Prof ; Walpole, Euan T, MBBS ; Finch-Jones, Meg, MD ; Jaeck, Daniel, Prof ; Mirza, Darius, FRCS ; Parks, Rowan W, MD ; Mauer, Murielle, PhD ; Tanis, Erik, MD ; Van Cutsem, Eric, Prof ; Scheithauer, Werner, Prof ; Gruenberger, Thomas, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-11, Vol.14 (12), p.1208-1215
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Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Author / Creator:Cabral, H. ; Matsumoto, Y. ; Mizuno, K. ; Chen, Q. ; Murakami, M. ; Kimura, M. ; Terada, Y. ; Kano, M. R. ; Miyazono, K. ; Uesaka, M. ; Nishiyama, N. ; Kataoka, K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2011-12, Vol.6 (12), p.815-823
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Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy
Author / Creator:Shalapour, Shabnam ; Font-Burgada, Joan ; Di Caro, Giuseppe ; Zhong, Zhenyu ; Sanchez-Lopez, Elsa ; Dhar, Debanjan ; Willimsky, Gerald ; Ammirante, Massimo ; Strasner, Amy ; Hansel, Donna E. ; Jamieson, Christina ; Kane, Christopher J. ; Klatte, Tobias ; Birner, Peter ; Kenner, Lukas ; Karin, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-05, Vol.521 (7550), p.94-98
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3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial
Author / Creator:Iveson, Timothy J ; Kerr, Rachel S ; Saunders, Mark P ; Cassidy, Jim ; Hollander, Niels Henrik ; Tabernero, Josep ; Haydon, Andrew ; Glimelius, Bengt ; Harkin, Andrea ; Allan, Karen ; McQueen, John ; Scudder, Claire ; Boyd, Kathleen Anne ; Briggs, Andrew ; Waterston, Ashita ; Medley, Louise ; Wilson, Charles ; Ellis, Richard ; Essapen, Sharadah ; Dhadda, Amandeep S ; Harrison, Mark ; Falk, Stephen ; Raouf, Sherif ; Rees, Charlotte ; Olesen, Rene K ; Propper, David ; Bridgewater, John ; Azzabi, Ashraf ; Farrugia, David ; Webb, Andrew ; Cunningham, David ; Hickish, Tamas ; Weaver, Andrew ; Gollins, Simon ; Wasan, Harpreet S ; Paul, James
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-04, Vol.19 (4), p.562-578
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Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group
Author / Creator:Simkens, Lieke H J, MD ; van Tinteren, Harm, PhD ; May, Anne, PhD ; ten Tije, Albert J, MD ; Creemers, Geert-Jan M, MD ; Loosveld, Olaf J L, MD ; de Jongh, Felix E, MD ; Erdkamp, Frans L G, MD ; Erjavec, Zoran, MD ; van der Torren, Adelheid M E, MD ; Tol, Jolien, MD ; Braun, Hans J J, MD ; Nieboer, Peter, MD ; van der Hoeven, Jacobus J M, Prof ; Haasjes, Janny G, MD ; Jansen, Rob L H, MD ; Wals, Jaap, MD ; Cats, Annemieke, MD ; Derleyn, Veerle A, MD ; Honkoop, Aafke H, MD ; Mol, Linda, MSc ; Punt, Cornelis J A, Prof ; Koopman, Miriam, Dr
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2015-05, Vol.385 (9980), p.1843-1852
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Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial
Author / Creator:FOxTROT Collaborative Group
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-11, Vol.13 (11), p.1152-1160
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Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, mu...
Author / Creator:Hong, Yong Sang, Prof ; Nam, Byung-Ho, Prof ; Kim, Kyu-pyo, Prof ; Kim, Jeong Eun, Prof ; Park, Seong Joon, MD ; Park, Young Suk, Prof ; Park, Joon Oh, Prof ; Kim, Sun Young, MD ; Kim, Tae-You, Prof ; Kim, Jee Hyun, Prof ; Ahn, Joong Bae, Prof ; Lim, Seok-Byung, Prof ; Yu, Chang Sik, Prof ; Kim, Jin Cheon, Prof ; Yun, Seong Hyeon, Prof ; Kim, Jong Hoon, Prof ; Park, Jin-hong, MD ; Park, Hee Chul, Prof ; Jung, Kyung Hae, Prof ; Kim, Tae Won, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-10, Vol.15 (11), p.1245-1253
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FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
Author / Creator:Conroy, Thierry ; Desseigne, Françoise ; Ychou, Marc ; Bouché, Olivier ; Guimbaud, Rosine ; Bécouarn, Yves ; Adenis, Antoine ; Raoul, Jean-Luc ; Gourgou-Bourgade, Sophie ; de la Fouchardière, Christelle ; Bennouna, Jaafar ; Bachet, Jean-Baptiste ; Khemissa-Akouz, Faiza ; Péré-Vergé, Denis ; Delbaldo, Catherine ; Assenat, Eric ; Chauffert, Bruno ; Michel, Pierre ; Montoto-Grillot, Christine ; Ducreux, Michel
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2011-05, Vol.364 (19), p.1817-1825
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Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial

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FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis

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Duration of Adjuvant Chemotherapy for Stage III Colon Cancer

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Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials

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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label,...

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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...

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Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): 5-year follow-up of an open-label, randomised phase 3 trial

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Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial

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Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicen...

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Pancreatic cancer

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Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-0...

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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...

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Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial

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Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

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Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

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3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial

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Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group

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Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial

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Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, mu...

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FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

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