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ArticlesPeer ReviewedFull Text
RNAi-mediated gene silencing in non-human primates
Author / Creator:Zimmermann, Tracy S. ; Lee, Amy C. H. ; Akinc, Akin ; Bramlage, Birgit ; Bumcrot, David ; Fedoruk, Matthew N. ; Harborth, Jens ; Heyes, James A. ; Jeffs, Lloyd B. ; John, Matthias ; Judge, Adam D. ; Lam, Kieu ; McClintock, Kevin ; Nechev, Lubomir V. ; Palmer, Lorne R. ; Racie, Timothy ; Röhl, Ingo ; Seiffert, Stephan ; Shanmugam, Sumi ; Sood, Vandana ; Soutschek, Jürgen ; Toudjarska, Ivanka ; Wheat, Amanda J. ; Yaworski, Ed ; Zedalis, William ; Koteliansky, Victor ; Manoharan, Muthiah ; Vornlocher, Hans-Peter ; MacLachlan, Ian
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-05, Vol.441 (7089), p.111-114
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Author / Creator:Huang, Shih-Min A. ; Mishina, Yuji M. ; Liu, Shanming ; Cheung, Atwood ; Stegmeier, Frank ; Michaud, Gregory A. ; Charlat, Olga ; Wiellette, Elizabeth ; Zhang, Yue ; Wiessner, Stephanie ; Hild, Marc ; Shi, Xiaoying ; Wilson, Christopher J. ; Mickanin, Craig ; Myer, Vic ; Fazal, Aleem ; Tomlinson, Ronald ; Serluca, Fabrizio ; Shao, Wenlin ; Cheng, Hong ; Shultz, Michael ; Rau, Christina ; Schirle, Markus ; Schlegl, Judith ; Ghidelli, Sonja ; Fawell, Stephen ; Lu, Chris ; Curtis, Daniel ; Kirschner, Marc W. ; Lengauer, Christoph ; Finan, Peter M. ; Tallarico, John A. ; Bouwmeester, Tewis ; Porter, Jeffery A. ; Bauer, Andreas ; Cong, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7264), p.614-620
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Antibacterial activity of ZnO nanoparticle suspensions on a broad spectrum of microorganisms
Author / Creator:Jones, Nicole ; Ray, Binata ; Ranjit, Koodali T ; Manna, Adhar C
Publisher:Oxford, UK: Oxford, UK : Blackwell Publishing Ltd
Journal title:FEMS microbiology letters, 2008-02, Vol.279 (1), p.71-76
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Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Author / Creator:Ro, D.K ; Paradise, E.M ; Ouellet, M ; Fisher, K.J ; Newman, K.L ; Ndungu, J.M ; Ho, K.A ; Eachus, R.A ; Ham, T.S ; Kirby, J
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-04, Vol.440 (7086), p.940-943
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Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc
Author / Creator:Anthony, Robert M ; Nimmerjahn, Falk ; Ashline, David J ; Reinhold, Vernon N ; Paulson, James C ; Ravetch, Jeffrey V
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-04, Vol.320 (5874), p.373-376
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Bioproduction of resveratrol and stilbene derivatives by plant cells and microorganisms
Author / Creator:Donnez, David ; Jeandet, Philippe ; Clément, Christophe ; Courot, Eric
Publisher:Cambridge, MA: Elsevier Ltd
Journal title:Trends in biotechnology (Regular ed.), 2009-12, Vol.27 (12), p.706-713
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Production of recombinant protein therapeutics in cultivated mammalian cells
Author / Creator:Wurm, Florian M
Publisher:London: Nature Publishing Group UK
Journal title:Nature biotechnology, 2004-11, Vol.22 (11), p.1393-1398
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Plant cell cultures for the production of recombinant proteins
Author / Creator:Hellwig, S ; Drossard, J ; Twyman, R.M ; Fischer, R
Publisher:London: Nature Publishing Group UK
Journal title:Nature biotechnology, 2004-11, Vol.22 (11), p.1415-1422
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Differential Targeting of Gβγ-Subunit Signaling with Small Molecules
Author / Creator:Bonacci, Tabetha M. ; Mathews, Jennifer L. ; Yuan, Chujun ; Lehmann, David M. ; Malik, Sundeep ; Wu, Dianqing ; Font, Jose L. ; Bidlack, Jean M. ; Smrcka, Alan V.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2006-04, Vol.312 (5772), p.443-446
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Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals
Author / Creator:Butler, Michael
Publisher:Berlin: Springer
Journal title:Applied microbiology and biotechnology, 2005-08, Vol.68 (3), p.283-291
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A small-molecule screen in C. elegans yields a new calcium channel antagonist
Author / Creator:Kwok, Trevor C. Y. ; Ricker, Nicole ; Fraser, Regina ; Chan, Allen W. ; Burns, Andrew ; Stanley, Elise F. ; McCourt, Peter ; Cutler, Sean R. ; Roy, Peter J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-05, Vol.441 (7089), p.91-95
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A linguistic model for the rational design of antimicrobial peptides
Author / Creator:Loose, Christopher ; Jensen, Kyle ; Rigoutsos, Isidore ; Stephanopoulos, Gregory
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-10, Vol.443 (7113), p.867-869
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Plants and human health in the twenty-first century
Author / Creator:Raskin, Ilya ; Ribnicky, David M. ; Komarnytsky, Slavko ; Ilic, Nebojsa ; Poulev, Alexander ; Borisjuk, Nikolai ; Brinker, Anita ; Moreno, Diego A. ; Ripoll, Christophe ; Yakoby, Nir ; O'Neal, Joseph M. ; Cornwell, Teresa ; Pastor, Ira ; Fridlender, Bertold
Publisher:Oxford: Elsevier Science
Journal title:Trends in biotechnology (Regular ed.), 2002-12, Vol.20 (12), p.522-531
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ArticlesPeer ReviewedFull Text
Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity
Author / Creator:Hoet, René Michael ; Cohen, Edward H ; Kent, Rachel Baribault ; Rookey, Kristin ; Schoonbroodt, Sonia ; Hogan, Shannon ; Rem, Louise ; Frans, Nicolas ; Daukandt, Marc ; Pieters, Henk ; van Hegelsom, Rob ; Neer, Nicole Coolen-van ; Nastri, Horacio G ; Rondon, Isaac J ; Leeds, Jennifer A ; Hufton, Simon E ; Huang, Lili ; Kashin, Irina ; Devlin, Mary ; Kuang, Guannan ; Steukers, Mieke ; Viswanathan, Malini ; Nixon, Andrew E ; Sexton, Daniel J ; Hoogenboom, Hennie R ; Ladner, Robert Charles
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2005-03, Vol.23 (3), p.344-348
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Characterizing biological products and assessing comparability following manufacturing changes
Author / Creator:Chirino, Arthur J ; Mire-Sluis, Anthony
Publisher:London: Nature Publishing Group UK
Journal title:Nature biotechnology, 2004-11, Vol.22 (11), p.1383-1391
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Strategies for efficient production of heterologous proteins in Escherichia coli
Author / Creator:JANA, S ; DEB, J. K
Publisher:Berlin: Springer
Journal title:Applied microbiology and biotechnology, 2005-05, Vol.67 (3), p.289-298
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Advances in the production of human therapeutic proteins in yeasts and filamentous fungi. [Erratum: 2004 Dec., v. 22, no. 12, p. 1589.]
Author / Creator:Gerngross, T.U
Publisher:London: Nature Publishing Group UK
Journal title:Nature biotechnology, 2004-11, Vol.22 (11), p.1409-1414
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Recombinant expression systems in the pharmaceutical industry
Author / Creator:Schmidt, F. R.
Publisher:Berlin: Springer
Journal title:Applied microbiology and biotechnology, 2004-09, Vol.65 (4), p.363-372
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Enhancement of therapeutic protein in vivo activities through glycoengineering
Author / Creator:Elliott, Steve ; Lorenzini, Tony ; Asher, Sheilah ; Aoki, Ken ; Brankow, David ; Buck, Lynette ; Busse, Leigh ; Chang, David ; Fuller, Janis ; Grant, James ; Hernday, Natasha ; Hokum, Martha ; Hu, Sylvia ; Knudten, Andrew ; Levin, Nancy ; Komorowski, Renee ; Martin, Frank ; Navarro, Rachell ; Osslund, Timothy ; Rogers, Gary ; Rogers, Norma ; Trail, Geri ; Egrie, Joan
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2003-04, Vol.21 (4), p.414-421
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Follow-on protein products: scientific issues, developments and challenges
Author / Creator:Rathore, Anurag S
Publisher:Cambridge, MA: Elsevier Ltd
Journal title:Trends in biotechnology (Regular ed.), 2009-12, Vol.27 (12), p.698-705
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Showing 1 to 20 of 249 results

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RNAi-mediated gene silencing in non-human primates

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

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Antibacterial activity of ZnO nanoparticle suspensions on a broad spectrum of microorganisms

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

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Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

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Bioproduction of resveratrol and stilbene derivatives by plant cells and microorganisms

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Production of recombinant protein therapeutics in cultivated mammalian cells

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Plant cell cultures for the production of recombinant proteins

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Differential Targeting of Gβγ-Subunit Signaling with Small Molecules

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Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals

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A small-molecule screen in C. elegans yields a new calcium channel antagonist

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A linguistic model for the rational design of antimicrobial peptides

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Plants and human health in the twenty-first century

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Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity

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Characterizing biological products and assessing comparability following manufacturing changes

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Strategies for efficient production of heterologous proteins in Escherichia coli

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Advances in the production of human therapeutic proteins in yeasts and filamentous fungi. [Erratum: 2004 Dec., v. 22, no. 12, p. 1589.]

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Recombinant expression systems in the pharmaceutical industry

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Enhancement of therapeutic protein in vivo activities through glycoengineering

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Follow-on protein products: scientific issues, developments and challenges

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