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The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature
Author / Creator:Inman, Gareth J. ; Wang, Jun ; Nagano, Ai ; Alexandrov, Ludmil B. ; Purdie, Karin J. ; Taylor, Richard G. ; Sherwood, Victoria ; Thomson, Jason ; Hogan, Sarah ; Spender, Lindsay C. ; South, Andrew P. ; Stratton, Michael ; Chelala, Claude ; Harwood, Catherine A. ; Proby, Charlotte M. ; Leigh, Irene M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-09, Vol.9 (1), p.3667-14, Article 3667
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NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
Author / Creator:South, Andrew P. ; Purdie, Karin J. ; Watt, Stephen A. ; Haldenby, Sam ; den Breems, Nicoline Y. ; Dimon, Michelle ; Arron, Sarah T. ; Kluk, Michael J. ; Aster, Jon C. ; McHugh, Angela ; Xue, Dylan J. ; Dayal, Jasbani H.S. ; Robinson, Kim S. ; Hasan Rizvi, S.M. ; Proby, Charlotte M. ; Harwood, Catherine A. ; Leigh, Irene M.
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-10, Vol.134 (10), p.2630-2638
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Genomic analysis of atypical fibroxanthoma
Author / Creator:Lai, Kevin ; Harwood, Catherine A. ; Purdie, Karin J. ; Proby, Charlotte M. ; Leigh, Irene M. ; Ravi, Namita ; Mully, Thaddeus W. ; Brooks, Lionel ; Sandoval, Priscilla M. ; Rosenblum, Michael D. ; Arron, Sarah T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-11, Vol.12 (11), p.e0188272
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Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
Author / Creator:Li Mow Chee, Frederic ; Beernaert, Bruno ; Griffith, Billie G. C. ; Loftus, Alexander E. P. ; Kumar, Yatendra ; Wills, Jimi C. ; Lee, Martin ; Valli, Jessica ; Wheeler, Ann P. ; Armstrong, J. Douglas ; Parsons, Maddy ; Leigh, Irene M. ; Proby, Charlotte M. ; von Kriegsheim, Alex ; Bickmore, Wendy A. ; Frame, Margaret C. ; Byron, Adam
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1602-1602, Article 1602
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Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression
Author / Creator:Bailey, Peter ; Ridgway, Rachel A. ; Cammareri, Patrizia ; Treanor-Taylor, Mairi ; Bailey, Ulla-Maja ; Schoenherr, Christina ; Bone, Max ; Schreyer, Daniel ; Purdie, Karin ; Thomson, Jason ; Rickaby, William ; Jackstadt, Rene ; Campbell, Andrew D. ; Dimonitsas, Emmanouil ; Stratigos, Alexander J. ; Arron, Sarah T. ; Wang, Jun ; Blyth, Karen ; Proby, Charlotte M. ; Harwood, Catherine A. ; Sansom, Owen J. ; Leigh, Irene M. ; Inman, Gareth J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-08, Vol.14 (1), p.5211-5211, Article 5211
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MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma
Author / Creator:Olasz, Edit B. ; Seline, Lauren N. ; Schock, Ashley M. ; Duncan, Nathan E. ; Lopez, Argelia ; Lazar, Jozef ; Flister, Michael J. ; Lu, Yan ; Liu, Pengyuan ; Sokumbi, Olayemi ; Harwood, Catherine A. ; Proby, Charlotte M. ; Neuburg, Marcy ; Lazarova, Zelmira
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-05, Vol.10 (5), p.e0125412-e0125412
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Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model
Author / Creator:Kalin, Jay H. ; Eroglu, Abdulkerim ; Liu, Hua ; Holtzclaw, W. David ; Leigh, Irene ; Proby, Charlotte M. ; Fahey, Jed W. ; Cole, Philip A. ; Dinkova-Kostova, Albena T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-03, Vol.14 (3), p.e0213095
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Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells
Author / Creator:Verschooten, Lien ; Barrette, Kathleen ; Van Kelst, Sofie ; Rubio Romero, Noemí ; Proby, Charlotte ; De Vos, Rita ; Agostinis, Patrizia ; Garmyn, Marjan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e48264-e48264
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Achieving integrated self-directed Cancer aftercare (ASICA) for melanoma: how a digital intervention to support total skin self-examination was used by people treated for cutaneous melanoma
Author / Creator:Reilly, Felicity ; Contstable, Lynda ; Brant, William ; Rahman, Kaz ; Durrani, Amer ; Burrows, Nigel ; Proby, Charlotte ; Allan, Julia ; Johnston, Marie ; Johnston, Derek ; Walter, Fiona ; Murchie, Peter
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2021-11, Vol.21 (1), p.1217-1217, Article 1217
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A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing
Author / Creator:Hassan, Sakinah ; Purdie, Karin J. ; Wang, Jun ; Harwood, Catherine A. ; Proby, Charlotte M. ; Pourreyron, Celine ; Mladkova, Nikol ; Nagano, Ai ; Dhayade, Sandeep ; Athineos, Dimitris ; Caley, Matthew ; Mannella, Viviana ; Blyth, Karen ; Inman, Gareth J. ; Leigh, Irene M.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-07, Vol.20 (14), p.3428
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Wnt5a Is Strongly Expressed at the Leading Edge in Non-Melanoma Skin Cancer, Forming Active Gradients, while Canonical Wnt Signalling Is Repressed
Author / Creator:Pourreyron, Celine ; Reilly, Louise ; Proby, Charlotte ; Panteleyev, Andrey ; Fleming, Colin ; McLean, Kathleen ; South, Andrew P. ; Foerster, John
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e31827-e31827
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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
Author / Creator:Kalin, Jay H. ; Wu, Muzhou ; Gomez, Andrea V. ; Song, Yun ; Das, Jayanta ; Hayward, Dawn ; Adejola, Nkosi ; Wu, Mingxuan ; Panova, Izabela ; Chung, Hye Jin ; Kim, Edward ; Roberts, Holly J. ; Roberts, Justin M. ; Prusevich, Polina ; Jeliazkov, Jeliazko R. ; Roy Burman, Shourya S. ; Fairall, Louise ; Milano, Charles ; Eroglu, Abdulkerim ; Proby, Charlotte M. ; Dinkova-Kostova, Albena T. ; Hancock, Wayne W. ; Gray, Jeffrey J. ; Bradner, James E. ; Valente, Sergio ; Mai, Antonello ; Anders, Nicole M. ; Rudek, Michelle A. ; Hu, Yong ; Ryu, Byungwoo ; Schwabe, John W. R. ; Mattevi, Andrea ; Alani, Rhoda M. ; Cole, Philip A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.53-13, Article 53
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Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
Author / Creator:Wang, Nicholas J ; Sanborn, Zachary ; Arnett, Kelly L ; Bayston, Laura J ; Liao, Wilson ; Proby, Charlotte M ; Leigh, Irene M ; Collisson, Eric A ; Gordon, Patricia B ; Jakkula, Lakshmi ; Pennypacker, Sally ; Zou, Yong ; Sharma, Mimansa ; North, Jeffrey P ; Vemula, Swapna S ; Mauro, Theodora M ; Neuhaus, Isaac M ; LeBoit, Philip E ; Hur, Joe S ; Park, Kyunghee ; Huh, Nam ; Kwok, Pui-Yan ; Arron, Sarah T ; Massion, Pierre P ; Bale, Allen E ; Haussler, David ; Cleaver, James E ; Gray, Joe W ; Spellman, Paul T ; South, Andrew P ; Aster, Jon C ; Blacklow, Stephen C ; Cho, Raymond J
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17761-17766
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The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial
Author / Creator:Murchie, Peter ; Constable, Lynda ; Hall, Susan ; Brant, William ; Allan, Julia ; Johnston, Marie ; Masthoff, Judith ; Lee, Amanda ; Treweek, Shaun ; Ayansina, Dolapo ; Proby, Charlotte ; Rahman, Kaz ; Walter, Fiona ; Burrows, Nigel ; Durrani, Amer ; Maclennan, Graeme
Publisher:Canada: JMIR Publications
Journal title:JMIR cancer, 2022-09, Vol.8 (3), p.e37539-e37539
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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
Author / Creator:Cammareri, Patrizia ; Rose, Aidan M. ; Vincent, David F. ; Wang, Jun ; Nagano, Ai ; Libertini, Silvana ; Ridgway, Rachel A. ; Athineos, Dimitris ; Coates, Philip J. ; McHugh, Angela ; Pourreyron, Celine ; Dayal, Jasbani H. S. ; Larsson, Jonas ; Weidlich, Simone ; Spender, Lindsay C. ; Sapkota, Gopal P. ; Purdie, Karin J. ; Proby, Charlotte M. ; Harwood, Catherine A. ; Leigh, Irene M. ; Clevers, Hans ; Barker, Nick ; Karlsson, Stefan ; Pritchard, Catrin ; Marais, Richard ; Chelala, Claude ; South, Andrew P. ; Sansom, Owen J. ; Inman, Gareth J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12493-14, Article 12493
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Keratotic Skin Lesions and Other Risk Factors Are Associated with Skin Cancer in Organ-Transplant Recipients: A Case–Control Study in The Netherlands, United Kingdom, Germany, France, and Italy
Author / Creator:Bouwes Bavinck, Jan N. ; Euvrard, Sylvie ; Naldi, Luigi ; Nindl, Ingo ; Proby, Charlotte M. ; Neale, Rachel ; Abeni, Damiano ; Tessari, Gian P. ; Feltkamp, Mariet C.W. ; Claudy, Alain ; Stockfleth, Eggert ; Harwood, Catherine A.
Publisher:Danvers, MA: Elsevier Inc
Journal title:Journal of investigative dermatology, 2007-07, Vol.127 (7), p.1647-1656
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Array Comparative Genomic Hybridization of Keratoacanthomas and Squamous Cell Carcinomas: Different Patterns of Genetic Aberrations Suggest Two Distinct Entities
Author / Creator:Li, Jian ; Wang, Kai ; Gao, Fei ; Jensen, Thomas D. ; Li, Shengting T. ; DeAngelis, Paula M. ; Kølvraa, Steen ; Proby, Charlotte ; Forslund, Ola ; Bolund, Lars ; Clausen, Ole Petter F.
Publisher:New York, NY: Elsevier Inc
Journal title:Journal of investigative dermatology, 2012-08, Vol.132 (8), p.2060-2066
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Are Keratoacanthomas Variants of Squamous Cell Carcinomas? A Comparison of Chromosomal Aberrations by Comparative Genomic Hybridization
Author / Creator:Clausen, Ole Petter F. ; Aass, Hans Christian D. ; Beigi, Marzieh ; Purdie, Karin J. ; Proby, Charlotte M. ; Brown, Victoria L. ; Mattingsdal, Morten ; Micci, Francesca ; Kølvraa, Steen ; Bolund, Lars ; DeAngelis, Paula M.
Publisher:Danvers, MA: Elsevier Inc
Journal title:Journal of investigative dermatology, 2006-10, Vol.126 (10), p.2308-2315
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Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs
Author / Creator:Purdie, Karin J. ; Harwood, Catherine A. ; Gulati, Abha ; Chaplin, Tracy ; Lambert, Sally R. ; Cerio, Rino ; Kelly, Gavin P. ; Cazier, Jean-Baptiste ; Young, Bryan D. ; Leigh, Irene M. ; Proby, Charlotte M.
Publisher:New York, NY: Elsevier Inc
Journal title:Journal of investigative dermatology, 2009-06, Vol.129 (6), p.1562-1568
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Human Papillomavirus Gene Expression in Cutaneous Squamous Cell Carcinomas from Immunosuppressed and Immunocompetent Individuals
Author / Creator:Purdie, Karin J. ; Surentheran, Thirunavukarasu ; Sterling, Jane C. ; Bell, Louise ; McGregor, Jane M. ; Proby, Charlotte M. ; Harwood, Catherine A. ; Breuer, Judith
Publisher:Danvers, MA: Elsevier Inc
Journal title:Journal of investigative dermatology, 2005-07, Vol.125 (1), p.98-107
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The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

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NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis

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Genomic analysis of atypical fibroxanthoma

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Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

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Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression

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MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma

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Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model

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Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

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Achieving integrated self-directed Cancer aftercare (ASICA) for melanoma: how a digital intervention to support total skin self-examination was used by people treated for cutaneous melanoma

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A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing

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Wnt5a Is Strongly Expressed at the Leading Edge in Non-Melanoma Skin Cancer, Forming Active Gradients, while Canonical Wnt Signalling Is Repressed

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

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Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

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The Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial

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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

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Keratotic Skin Lesions and Other Risk Factors Are Associated with Skin Cancer in Organ-Transplant Recipients: A Case–Control Study in The Netherlands, United Kingdom, Germany, France, and Italy

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Array Comparative Genomic Hybridization of Keratoacanthomas and Squamous Cell Carcinomas: Different Patterns of Genetic Aberrations Suggest Two Distinct Entities

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Are Keratoacanthomas Variants of Squamous Cell Carcinomas? A Comparison of Chromosomal Aberrations by Comparative Genomic Hybridization

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Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs

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Human Papillomavirus Gene Expression in Cutaneous Squamous Cell Carcinomas from Immunosuppressed and Immunocompetent Individuals

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