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ArticlesPeer ReviewedFull Text
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing
Author / Creator:Sifrim, Alejandro ; Hitz, Marc-Phillip ; Wilsdon, Anna ; Breckpot, Jeroen ; Turki, Saeed H Al ; Thienpont, Bernard ; McRae, Jeremy ; Fitzgerald, Tomas W ; Singh, Tarjinder ; Swaminathan, Ganesh Jawahar ; Prigmore, Elena ; Rajan, Diana ; Abdul-Khaliq, Hashim ; Banka, Siddharth ; Bauer, Ulrike M M ; Bentham, Jamie ; Berger, Felix ; Bhattacharya, Shoumo ; Bu'Lock, Frances ; Canham, Natalie ; Colgiu, Irina-Gabriela ; Cosgrove, Catherine ; Cox, Helen ; Daehnert, Ingo ; Daly, Allan ; Danesh, John ; Fryer, Alan ; Gewillig, Marc ; Hobson, Emma ; Hoff, Kirstin ; Homfray, Tessa ; Kahlert, Anne-Karin ; Ketley, Ami ; Kramer, Hans-Heiner ; Lachlan, Katherine ; Lampe, Anne Katrin ; Louw, Jacoba J ; Manickara, Ashok Kumar ; Manase, Dorin ; McCarthy, Karen P ; Metcalfe, Kay ; Moore, Carmel ; Newbury-Ecob, Ruth ; Omer, Seham Osman ; Ouwehand, Willem H ; Park, Soo-Mi ; Parker, Michael J ; Pickardt, Thomas ; Pollard, Martin O ; Robert, Leema ; Roberts, David J ; Sambrook, Jennifer ; Setchfield, Kerry ; Stiller, Brigitte ; Thornborough, Chris ; Toka, Okan ; Watkins, Hugh ; Williams, Denise ; Wright, Michael ; Mital, Seema ; Daubeney, Piers E F ; Keavney, Bernard ; Goodship, Judith ; Abu-Sulaiman, Riyadh Mahdi ; Klaassen, Sabine ; Wright, Caroline F ; Firth, Helen V ; Barrett, Jeffrey C ; Devriendt, Koenraad ; FitzPatrick, David R ; Brook, J David ; Hurles, Matthew E
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-09, Vol.48 (9), p.1060-1065
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ArticlesPeer ReviewedFull Text
Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells
Author / Creator:Bian, Zhen ; Shi, Lei ; Guo, Ya-Lan ; Lv, Zhiyuan ; Tang, Cong ; Niu, Shuo ; Tremblay, Alexandra ; Venkataramani, Mahathi ; Culpepper, Courtney ; Li, Limin ; Zhou, Zhen ; Mansour, Ahmed ; Zhang, Yongliang ; Gewirtz, Andrew ; Kidder, Koby ; Zen, Ke ; Liu, Yuan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.E5434-E5443
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ArticlesPeer ReviewedFull Text
Protein kinase C and cancer: what we know and what we do not
Author / Creator:Garg, R ; Benedetti, L G ; Abera, M B ; Wang, H ; Abba, M ; Kazanietz, M G
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2014-11, Vol.33 (45), p.5225-5237
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ArticlesPeer ReviewedFull Text
Renal plasticity revealed through reversal of polycystic kidney disease in mice
Author / Creator:Dong, Ke ; Zhang, Chao ; Tian, Xin ; Coman, Daniel ; Hyder, Fahmeed ; Ma, Ming ; Somlo, Stefan
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-12, Vol.53 (12), p.1649-1663
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ArticlesPeer ReviewedFull Text
Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis
Author / Creator:Dong, Zhifang ; Han, Huili ; Li, Hongjie ; Bai, Yanrui ; Wang, Wei ; Tu, Man ; Peng, Yan ; Zhou, Limin ; He, Wenting ; Wu, Xiaobin ; Tan, Tao ; Liu, Mingjing ; Wu, Xiaoyan ; Zhou, Weihui ; Jin, Wuyang ; Zhang, Shu ; Sacktor, Todd Charlton ; Li, Tingyu ; Song, Weihong ; Wang, Yu Tian
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-01, Vol.125 (1), p.234-247
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ArticlesPeer ReviewedFull Text
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands
Author / Creator:Weinreb, Ilan ; Piscuoglio, Salvatore ; Martelotto, Luciano G ; Waggott, Daryl ; Ng, Charlotte K Y ; Perez-Ordonez, Bayardo ; Harding, Nicholas J ; Alfaro, Javier ; Chu, Kenneth C ; Viale, Agnes ; Fusco, Nicola ; da Cruz Paula, Arnaud ; Marchio, Caterina ; Sakr, Rita A ; Lim, Raymond ; Thompson, Lester D R ; Chiosea, Simion I ; Seethala, Raja R ; Skalova, Alena ; Stelow, Edward B ; Fonseca, Isabel ; Assaad, Adel ; How, Christine ; Wang, Jianxin ; de Borja, Richard ; Chan-Seng-Yue, Michelle ; Howlett, Christopher J ; Nichols, Anthony C ; Wen, Y Hannah ; Katabi, Nora ; Buchner, Nicholas ; Mullen, Laura ; Kislinger, Thomas ; Wouters, Bradly G ; Liu, Fei-Fei ; Norton, Larry ; McPherson, John D ; Rubin, Brian P ; Clarke, Blaise A ; Weigelt, Britta ; Boutros, Paul C ; Reis-Filho, Jorge S
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2014-11, Vol.46 (11), p.1166-1169
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ArticlesPeer ReviewedFull Text
Prkcz null mice show normal learning and memory
Author / Creator:Lee, Anna M. ; Kanter, Benjamin R. ; Wang, Dan ; Lim, Jana P. ; Zou, Mimi E. ; Qiu, Chichen ; McMahon, Thomas ; Dadgar, Jahan ; Fischbach-Weiss, Sarah C. ; Messing, Robert O.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-01, Vol.493 (7432), p.416-419
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ArticlesPeer ReviewedFull Text
De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy
Author / Creator:Barcia, Giulia ; Fleming, Matthew R ; Deligniere, Aline ; Gazula, Valeswara-Rao ; Brown, Maile R ; Langouet, Maeva ; Chen, Haijun ; Kronengold, Jack ; Abhyankar, Avinash ; Cilio, Roberta ; Nitschke, Patrick ; Kaminska, Anna ; Boddaert, Nathalie ; Casanova, Jean-Laurent ; Desguerre, Isabelle ; Munnich, Arnold ; Dulac, Olivier ; Kaczmarek, Leonard K ; Colleaux, Laurence ; Nabbout, Rima
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2012-11, Vol.44 (11), p.1255-1259
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ArticlesPeer ReviewedFull Text
PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory
Author / Creator:Volk, Lenora J. ; Bachman, Julia L. ; Johnson, Richard ; Yu, Yilin ; Huganir, Richard L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-01, Vol.493 (7432), p.420-423
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ArticlesPeer ReviewedFull Text
Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
Author / Creator:Jin, Young-June ; Chennupati, Ramesh ; Li, Rui ; Liang, Guozheng ; Wang, ShengPeng ; Iring, András ; Graumann, Johannes ; Wettschureck, Nina ; Offermanns, Stefan
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-11, Vol.131 (21), p.1-16
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ArticlesPeer ReviewedFull Text
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission
Author / Creator:Yarwood, Rebecca E. ; Imlach, Wendy L. ; Lieu, TinaMarie ; Veldhuis, Nicholas A. ; Jensen, Dane D. ; Herenbrink, Carmen Klein ; Aurelio, Luigi ; Cai, Zhijian ; Christie, MacDonald J. ; Poole, Daniel P. ; Porter, Christopher J. H. ; McLean, Peter ; Hicks, Gareth A. ; Geppetti, Pierangelo ; Halls, Michelle L. ; Canals, Meritxell ; Bunnett, Nigel W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (46), p.12309-12314
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ArticlesPeer ReviewedFull Text
Equivocal, explicit and emergent actions of PKC isoforms in cancer
Author / Creator:Parker, Peter J. ; Brown, Sophie J. ; Calleja, Veronique ; Chakravarty, Probir ; Cobbaut, Mathias ; Linch, Mark ; Marshall, Jacqueline J. T. ; Martini, Silvia ; McDonald, Neil Q. ; Soliman, Tanya ; Watson, Lisa
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2021-01, Vol.21 (1), p.51-63
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PKC and the control of localized signal dynamics
Author / Creator:Rosse, Carine ; Linch, Mark ; Kermorgant, Stéphanie ; Cameron, Angus J. M. ; Boeckeler, Katrina ; Parker, Peter J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2010-02, Vol.11 (2), p.103-112
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Systems-level identification of PKA-dependent signaling in epithelial cells
Author / Creator:Isobe, Kiyoshi ; Jung, Hyun Jun ; Yang, Chin-Rang ; Claxton, J’Neka ; Sandoval, Pablo ; Burg, Maurice B. ; Raghuram, Viswanathan ; Knepper, Mark A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (42), p.E8875-E8884
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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
Author / Creator:Shigeto, Makoto ; Ramracheya, Reshma ; Tarasov, Andrei I ; Cha, Chae Young ; Chibalina, Margarita V ; Hastoy, Benoit ; Philippaert, Koenraad ; Reinbothe, Thomas ; Rorsman, Nils ; Salehi, Albert ; Sones, William R ; Vergari, Elisa ; Weston, Cathryn ; Gorelik, Julia ; Katsura, Masashi ; Nikolaev, Viacheslav O ; Vennekens, Rudi ; Zaccolo, Manuela ; Galione, Antony ; Johnson, Paul R V ; Kaku, Kohei ; Ladds, Graham ; Rorsman, Patrik
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4714-4728
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ArticlesPeer ReviewedFull Text
Latency reversal plus natural killer cells diminish HIV reservoir in vivo
Author / Creator:Kim, Jocelyn T. ; Zhang, Tian-Hao ; Carmona, Camille ; Lee, Bryanna ; Seet, Christopher S. ; Kostelny, Matthew ; Shah, Nisarg ; Chen, Hongying ; Farrell, Kylie ; Soliman, Mohamed S. A. ; Dimapasoc, Melanie ; Sinani, Michelle ; Blanco, Kenia Yazmin Reyna ; Bojorquez, David ; Jiang, Hong ; Shi, Yuan ; Du, Yushen ; Komarova, Natalia L. ; Wodarz, Dominik ; Wender, Paul A. ; Marsden, Matthew D. ; Sun, Ren ; Zack, Jerome A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.121-14, Article 121
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ArticlesPeer ReviewedFull Text
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas
Author / Creator:Atwood, Scott X. ; Li, Mischa ; Lee, Alex ; Tang, Jean Y. ; Oro, Anthony E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-02, Vol.494 (7438), p.484-488
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ArticlesPeer ReviewedFull Text
Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes
Author / Creator:Pasquier, Adrien ; Vivot, Kevin ; Erbs, Eric ; Spiegelhalter, Coralie ; Zhang, Zhirong ; Aubert, Victor ; Liu, Zengzhen ; Senkara, Meryem ; Maillard, Elisa ; Pinget, Michel ; Kerr-Conte, Julie ; Pattou, François ; Marciniak, Gilbert ; Ganzhorn, Axel ; Ronchi, Paolo ; Schieber, Nicole L. ; Schwab, Yannick ; Saftig, Paul ; Goginashvili, Alexander ; Ricci, Romeo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3312-14, Article 3312
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ArticlesPeer ReviewedFull Text
A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior
Author / Creator:Tashima, Ryoichi ; Koga, Keisuke ; Yoshikawa, Yu ; Sekine, Misuzu ; Watanabe, Moeka ; Tozaki-Saitoh, Hidetoshi ; Furue, Hidemasa ; Yasaka, Toshiharu ; Tsuda, Makoto
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (3), p.1-10
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ArticlesPeer ReviewedFull Text
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination
Author / Creator:Watanave, Masashi ; Takahashi, Nobutaka ; Hosoi, Nobutake ; Konno, Ayumu ; Yamamoto, Hikaru ; Yasui, Hiroyuki ; Kawachi, Mika ; Horii, Takuro ; Matsuzaki, Yasunori ; Hatada, Izuho ; Hirai, Hirokazu
Publisher:United States
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (7)
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Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing

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Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells

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Protein kinase C and cancer: what we know and what we do not

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Renal plasticity revealed through reversal of polycystic kidney disease in mice

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Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

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Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands

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Prkcz null mice show normal learning and memory

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De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy

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PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory

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Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation

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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

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Equivocal, explicit and emergent actions of PKC isoforms in cancer

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PKC and the control of localized signal dynamics

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Systems-level identification of PKA-dependent signaling in epithelial cells

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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

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Latency reversal plus natural killer cells diminish HIV reservoir in vivo

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GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas

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Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes

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A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

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Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination

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