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8,034 results for Protein+Kinases+-+genetics

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ArticlesPeer ReviewedFull Text
Energy-stress-mediated AMPK activation inhibits ferroptosis
Author / Creator:Lee, Hyemin ; Zandkarimi, Fereshteh ; Zhang, Yilei ; Meena, Jitendra Kumar ; Kim, Jongchan ; Zhuang, Li ; Tyagi, Siddhartha ; Ma, Li ; Westbrook, Thomas F. ; Steinberg, Gregory R. ; Nakada, Daisuke ; Stockwell, Brent R. ; Gan, Boyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-02, Vol.22 (2), p.225-234
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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Author / Creator:Peltzer, Nieves ; Darding, Maurice ; Montinaro, Antonella ; Draber, Peter ; Draberova, Helena ; Kupka, Sebastian ; Rieser, Eva ; Fisher, Amanda ; Hutchinson, Ciaran ; Taraborrelli, Lucia ; Hartwig, Torsten ; Lafont, Elodie ; Haas, Tobias L. ; Shimizu, Yutaka ; Böiers, Charlotta ; Sarr, Aida ; Rickard, James ; Alvarez-Diaz, Silvia ; Ashworth, Michael T. ; Beal, Allison ; Enver, Tariq ; Bertin, John ; Kaiser, William ; Strasser, Andreas ; Silke, John ; Bouillet, Philippe ; Walczak, Henning
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-05, Vol.557 (7703), p.112-117
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Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells
Author / Creator:Jin, Guoxiang ; Xu, Chuan ; Zhang, Xian ; Long, Jie ; Rezaeian, Abdol Hossein ; Liu, Chunfang ; Furth, Mark E. ; Kridel, Steven ; Pasche, Boris ; Bian, Xiu-Wu ; Lin, Hui-Kuan
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-01, Vol.19 (1), p.29-40
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The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis
Author / Creator:Günther, Claudia ; He, Gui-Wei ; Kremer, Andreas E. ; Murphy, James M. ; Petrie, Emma J. ; Amann, Kerstin ; Vandenabeele, Peter ; Linkermann, Andreas ; Poremba, Christopher ; Schleicher, Ulrike ; Dewitz, Christin ; Krautwald, Stefan ; Neurath, Markus F. ; Becker, Christoph ; Wirtz, Stefan
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-11, Vol.126 (11), p.4346-4360
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Factors underlying sensitivity of cancers to small-molecule kinase inhibitors
Author / Creator:Jänne, Pasi A. ; Gray, Nathanael ; Settleman, Jeff
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2009-09, Vol.8 (9), p.709-723
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GATA-Dependent Glutaminolysis Drives Appressorium Formation in Magnaporthe oryzae by Suppressing TOR Inhibition of cAMP/PKA Signaling
Author / Creator:Marroquin-Guzman, Margarita ; Wilson, Richard A.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-04, Vol.11 (4), p.e1004851-e1004851
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CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma
Author / Creator:Hong, Jian ; Hu, Kaishun ; Yuan, Yunfei ; Sang, Yi ; Bu, Qiangui ; Chen, Guihua ; Yang, Longjun ; Li, Binkui ; Huang, Pinzhu ; Chen, Dongtai ; Liang, Yi ; Zhang, Ruhua ; Pan, Jingxuan ; Zeng, Yi-Xin ; Kang, Tiebang
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-06, Vol.122 (6), p.2165-2175
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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
Author / Creator:Majumder, Pradip K ; Febbo, Phillip G ; Bikoff, Rachel ; Berger, Raanan ; Xue, Qi ; McMahon, Louis M ; Manola, Judith ; Brugarolas, James ; McDonnell, Timothy J ; Golub, Todd R ; Loda, Massimo ; Lane, Heidi A ; Sellers, William R
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2004-06, Vol.10 (6), p.594-601
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A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation
Author / Creator:Yang, Shen-Hsi ; Kalkan, Tuzer ; Morrisroe, Claire ; Smith, Austin ; Sharrocks, Andrew D.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2012-12, Vol.8 (12), p.e1003112-e1003112
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CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma
Author / Creator:Mitsui, Yozo ; Chang, Inik ; Fukuhara, Shinichiro ; Hiraki, Miho ; Arichi, Naoko ; Yasumoto, Hiroaki ; Hirata, Hiroshi ; Yamamura, Soichiro ; Shahryari, Varahram ; Deng, Guoren ; Wong, Darryn K. ; Majid, Shahana ; Shiina, Hiroaki ; Dahiya, Rajvir ; Tanaka, Yuichiro
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2015-12, Vol.15 (1), p.942-942, Article 942
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ArticlesPeer ReviewedFull Text
AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin
Author / Creator:Garcin, Geneviève ; Guiraud, Isabelle ; Lacroix, Matthieu ; Genthon, Clémence ; Rialle, Stéphanie ; Joujoux, Jean-Marie ; Meunier, Laurent ; Lavabre-Bertrand, Thierry ; Stoebner, Pierre-Emmanuel ; Le Gallic, Lionel
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2015-11, Vol.135 (11), p.2732-2741
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ArticlesPeer ReviewedFull Text
Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
Author / Creator:Lossaint, G ; Besnard, E ; Fisher, D ; Piette, J ; Dulić, V
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2011-10, Vol.30 (41), p.4261-4274
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Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence
Author / Creator:Kadekar, Pratik ; Chaouni, Rita ; Clark, Emily ; Kazanets, Anna ; Roy, Richard
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2018-06, Vol.19 (1), p.462-462, Article 462
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Pattern-Triggered Immunity Suppresses Programmed Cell Death Triggered by Fumonisin B1
Author / Creator:Igarashi, Daisuke ; Bethke, Gerit ; Xu, Yuan ; Tsuda, Kenichi ; Glazebrook, Jane ; Katagiri, Fumiaki
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e60769
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ArticlesPeer ReviewedFull Text
Is kinase activity essential for biological functions of BRI1
Author / Creator:Xu, Weihui ; Huang, Juan ; Li, Baohua ; Li, Jiayang ; Wang, Yonghong
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2008-04, Vol.18 (4), p.472-478
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ArticlesPeer ReviewedFull Text
DHEA Alleviates Oxidative Stress of Muscle Cells via Activation of Nrf2 Pathway
Author / Creator:Jeon, Songhee ; Hur, Jinyoung ; Kim, Jongpil
Publisher:New York: Springer-Verlag
Journal title:Applied biochemistry and biotechnology, 2015-05, Vol.176 (1), p.22-32
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ArticlesPeer ReviewedFull Text
Os-1 family histidine kinase from a filamentous fungus confers fungicide-sensitivity to yeast
Author / Creator:Motoyama, T ; Ohira, T ; Kadokura, K ; Ichiishi, A ; Fujimura, M ; Yamaguchi, I ; Kudo, T
Publisher:United States: Springer Nature B.V
Journal title:Current genetics, 2005-05, Vol.47 (5), p.298-306
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ArticlesPeer ReviewedFull Text
Bruchpilot in Ribbon-Like Axonal Agglomerates, Behavioral Defects, and Early Death in SRPK79D Kinase Mutants of Drosophila
Author / Creator:Nieratschker, Vanessa ; Schubert, Alice ; Jauch, Mandy ; Bock, Nicole ; Bucher, Daniel ; Dippacher, Sonja ; Krohne, Georg ; Asan, Esther ; Buchner, Sigrid ; Buchner, Erich
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2009-10, Vol.5 (10), p.e1000700-e1000700
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ArticlesPeer ReviewedFull Text
Stress-responsive gene TauT and acute kidney injury
Author / Creator:Han, Xiaobin ; Chesney, Russell W
Publisher:England: BioMed Central Ltd
Journal title:Journal of biomedical science, 2010-08, Vol.17 (Suppl 1), p.S28-S28
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ArticlesPeer ReviewedFull Text
Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks
Author / Creator:Liu, Kun-hsiang ; Niu, Yajie ; Konishi, Mineko ; Wu, Yue ; Du, Hao ; Sun Chung, Hoo ; Li, Lei ; Boudsocq, Marie ; McCormack, Matthew ; Maekawa, Shugo ; Ishida, Tetsuya ; Zhang, Chao ; Shokat, Kevan ; Yanagisawa, Shuichi ; Sheen, Jen
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-05, Vol.545 (7654), p.311-316
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Energy-stress-mediated AMPK activation inhibits ferroptosis

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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

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Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells

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The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis

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Factors underlying sensitivity of cancers to small-molecule kinase inhibitors

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GATA-Dependent Glutaminolysis Drives Appressorium Formation in Magnaporthe oryzae by Suppressing TOR Inhibition of cAMP/PKA Signaling

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CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma

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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

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A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation

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CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

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AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin

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Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional

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Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence

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Pattern-Triggered Immunity Suppresses Programmed Cell Death Triggered by Fumonisin B1

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Is kinase activity essential for biological functions of BRI1

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DHEA Alleviates Oxidative Stress of Muscle Cells via Activation of Nrf2 Pathway

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Os-1 family histidine kinase from a filamentous fungus confers fungicide-sensitivity to yeast

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Bruchpilot in Ribbon-Like Axonal Agglomerates, Behavioral Defects, and Early Death in SRPK79D Kinase Mutants of Drosophila

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Stress-responsive gene TauT and acute kidney injury

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Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks

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