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397 results for Protein+Tyrosine+Phosphatase,+Non-Receptor+Type+6

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ArticlesPeer ReviewedFull Text
SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3
Author / Creator:Yin, Songna ; Wu, Haibo ; Lv, Jiaxing ; Wu, Xinying ; Zhang, Yan ; Du, Juan ; Zhang, Yong
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e86330-e86330
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Aberrant promoter 2 methylation‑mediated downregulation of protein tyrosine phosphatase, non‑receptor type 6, is associated with progression of esophageal squamous cell carcinoma
Author / Creator:Liu, Lei ; Zhang, Shaowei ; Liu, Xinbo ; Liu, Junfeng
Publisher:Greece: Spandidos Publications
Journal title:Molecular medicine reports, 2019-04, Vol.19 (4), p.3273-3282
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Reduced capsaicin-induced mechanical allodynia and neuronal responses in the dorsal root ganglion in the presence of protein tyrosine phosphatase non-receptor type 6 overexpression
Author / Creator:Vroman, Robin ; Ishihara, Shingo ; Fullam, Spencer ; Wood, Matthew J ; Adamczyk, Natalie S ; Lomeli, Nolan ; Malfait, Fransiska ; Malfait, Anne-Marie ; Miller, Rachel E ; Markovics, Adrienn
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Molecular pain, 2024-01, Vol.20, p.17448069241258106
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THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1
Author / Creator:Choi, Seeyoung ; Warzecha, Claude ; Zvezdova, Ekaterina ; Lee, Jan ; Argenty, Jérémy ; Lesourne, Renaud ; Aravind, L ; Love, Paul E
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2017-04, Vol.18 (4), p.433-441
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Balancing immune response: SHP1 controls neutrophil activation in inflamed lungs
Author / Creator:Ghimire, Laxman ; Luo, Hongbo R.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-12, Vol.134 (24)
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RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3
Author / Creator:Lukens, John R. ; Vogel, Peter ; Johnson, Gordon R. ; Kelliher, Michelle A. ; Iwakura, Yoichiro ; Lamkanfi, Mohamed ; Kanneganti, Thirumala-Devi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-06, Vol.498 (7453), p.224-227
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Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis
Author / Creator:Flores, Alyssa M. ; Hosseini-Nassab, Niloufar ; Jarr, Kai-Uwe ; Ye, Jianqin ; Zhu, Xingjun ; Wirka, Robert ; Koh, Ai Leen ; Tsantilas, Pavlos ; Wang, Ying ; Nanda, Vivek ; Kojima, Yoko ; Zeng, Yitian ; Lotfi, Mozhgan ; Sinclair, Robert ; Weissman, Irving L. ; Ingelsson, Erik ; Smith, Bryan Ronain ; Leeper, Nicholas J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2020-02, Vol.15 (2), p.154-161
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Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia
Author / Creator:Chen, Zhengshan ; Shojaee, Seyedmehdi ; Buchner, Maike ; Geng, Huimin ; Lee, Jae Woong ; Klemm, Lars ; Titz, Björn ; Graeber, Thomas G. ; Park, Eugene ; Tan, Ying Xim ; Satterthwaite, Anne ; Paietta, Elisabeth ; Hunger, Stephen P. ; Willman, Cheryl L. ; Melnick, Ari ; Loh, Mignon L. ; Jung, Jae U. ; Coligan, John E. ; Bolland, Silvia ; Mak, Tak W. ; Limnander, Andre ; Jumaa, Hassan ; Reth, Michael ; Weiss, Arthur ; Lowell, Clifford A. ; Müschen, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-05, Vol.521 (7552), p.357-361
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Multi-omic analyses reveal PTPN6’s impact on tumor immunity across various cancers
Author / Creator:Zhong, Yuchen ; Zhang, Weiyuan ; Zheng, Chaojing ; Wu, Hongyu ; Luo, Jun ; Yuan, Ziming ; Zhang, Hao ; Wang, Chunlin ; Feng, Haiyang ; Wang, Meng ; Zhang, Qian ; Ju, Haixing ; Wang, Guiyu
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-04, Vol.15 (1), p.11025-21, Article 11025
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Allicin Inhibits Proliferation and Invasion in Vitro and in Vivo via SHP-1-Mediated STAT3 Signaling in Cholangiocarcinoma
Author / Creator:Chen, Huinan ; Zhu, Biqiang ; Zhao, Lei ; Liu, Yang ; Zhao, Fuya ; Feng, Jing ; Jin, Ye ; Sun, Jiayu ; Geng, Rui ; Wei, Yunwei
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2018-01, Vol.47 (2), p.641-653
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Epigenome-wide association studies identify DNA methylation associated with kidney function
Author / Creator:Chu, Audrey Y. ; Tin, Adrienne ; Schlosser, Pascal ; Ko, Yi-An ; Qiu, Chengxiang ; Yao, Chen ; Joehanes, Roby ; Grams, Morgan E. ; Liang, Liming ; Gluck, Caroline A. ; Liu, Chunyu ; Coresh, Josef ; Hwang, Shih-Jen ; Levy, Daniel ; Boerwinkle, Eric ; Pankow, James S. ; Yang, Qiong ; Fornage, Myriam ; Fox, Caroline S. ; Susztak, Katalin ; Köttgen, Anna
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1286-12, Article 1286
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SHP1 loss augments DLBCL cellular response to ibrutinib: a candidate predictive biomarker
Author / Creator:Wu, Wenjun ; Lu, Pin ; Patel, Priyal ; Ma, Ji ; Cai, Kathy Qi ; Mallikarjuna, Vinay S. ; Poureghbali, Sahar ; Nakhoda, Shazia R. ; Nejati, Reza ; Lynn Wang, Y.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2023-02, Vol.42 (6), p.409-420
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Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
Author / Creator:Tai, W-T ; Shiau, C-W ; Chen, H-L ; Liu, C-Y ; Lin, C-S ; Cheng, A-L ; Chen, P-J ; Chen, K-F
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2013-02, Vol.4 (2), p.e485-e485
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trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop
Author / Creator:Hirata, Yusuke ; Inoue, Aya ; Suzuki, Saki ; Takahashi, Miki ; Matsui, Ryosuke ; Kono, Nozomu ; Noguchi, Takuya ; Matsuzawa, Atsushi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.2743, Article 2743
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SHP-1 phosphatase activity counteracts increased T cell receptor affinity
Author / Creator:Hebeisen, Michael ; Baitsch, Lukas ; Presotto, Danilo ; Baumgaertner, Petra ; Romero, Pedro ; Michielin, Olivier ; Speiser, Daniel E. ; Rufer, Nathalie
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-03, Vol.123 (3), p.1044-1056
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ArticlesPeer ReviewedFull Text
NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis
Author / Creator:Gurung, Prajwal ; Burton, Amanda ; Kanneganti, Thirumala-Devi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (16), p.4452-4457
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ArticlesPeer ReviewedFull Text
Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans
Author / Creator:Giovannone, N. ; Liang, J. ; Antonopoulos, A. ; Geddes Sweeney, J. ; King, S. L. ; Pochebit, S. M. ; Bhattacharyya, N. ; Lee, G. S. ; Dell, A. ; Widlund, H. R. ; Haslam, S. M. ; Dimitroff, C. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3287-17, Article 3287
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ArticlesPeer ReviewedFull Text
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Author / Creator:Othman, Amira ; Ahmad, Saif ; Megyerdi, Sylvia ; Mussell, Rene ; Choksi, Karishma ; Maddipati, Krishna Rao ; Elmarakby, Ahmed ; Rizk, Nasser ; Al-Shabrawey, Mohamed
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e57254
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ArticlesPeer ReviewedFull Text
The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I–peptide complex formation
Author / Creator:Ding, Yuanyuan ; Guo, Zhenhong ; Liu, Yiqi ; Li, Xia ; Zhang, Qian ; Xu, Xiongfei ; Gu, Yan ; Zhang, Yi ; Zhao, Dezhi ; Cao, Xuetao
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-10, Vol.17 (10), p.1167-1175
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TREM2 aggravates sepsis by inhibiting fatty acid oxidation via the SHP1/BTK axis
Author / Creator:Ming, Siqi ; Li, Xingyu ; Xiao, Qiang ; Qu, Siying ; Wang, Qiaohua ; Fang, Qiongyan ; Liang, Pingping ; Xu, Yating ; Yang, Jingwen ; Yang, Yongqiang ; Huang, Xi ; Wu, Yongjian
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2025-01, Vol.135 (1), p.1-16
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SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3

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Aberrant promoter 2 methylation‑mediated downregulation of protein tyrosine phosphatase, non‑receptor type 6, is associated with progression of esophageal squamous cell carcinoma

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Reduced capsaicin-induced mechanical allodynia and neuronal responses in the dorsal root ganglion in the presence of protein tyrosine phosphatase non-receptor type 6 overexpression

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THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1

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Balancing immune response: SHP1 controls neutrophil activation in inflamed lungs

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RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3

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Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

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Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

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Multi-omic analyses reveal PTPN6’s impact on tumor immunity across various cancers

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Allicin Inhibits Proliferation and Invasion in Vitro and in Vivo via SHP-1-Mediated STAT3 Signaling in Cholangiocarcinoma

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Epigenome-wide association studies identify DNA methylation associated with kidney function

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SHP1 loss augments DLBCL cellular response to ibrutinib: a candidate predictive biomarker

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Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells

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trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop

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SHP-1 phosphatase activity counteracts increased T cell receptor affinity

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NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis

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Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

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The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I–peptide complex formation

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TREM2 aggravates sepsis by inhibiting fatty acid oxidation via the SHP1/BTK axis

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