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Pim-1 regulates cardiomyocyte survival downstream of Akt
Author / Creator:Muraski, John A ; Rota, Marcello ; Misao, Yu ; Fransioli, Jenna ; Cottage, Christopher ; Gude, Natalie ; Esposito, Grazia ; Delucchi, Francesca ; Arcarese, Michael ; Alvarez, Roberto ; Siddiqi, Sailay ; Emmanuel, Gregory N ; Wu, Weitao ; Fischer, Kimberlee ; Martindale, Joshua J ; Glembotski, Christopher C ; Leri, Annarosa ; Kajstura, Jan ; Magnuson, Nancy ; Berns, Anton ; Beretta, Remus M ; Houser, Steven R ; Schaefer, Erik M ; Anversa, Piero ; Sussman, Mark A
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2007-12, Vol.13 (12), p.1467-1475
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MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma
Author / Creator:Deng, Danni ; Wang, Lei ; Chen, Yao ; Li, Bowen ; Xue, Lian ; Shao, Naiyuan ; Wang, Qiang ; Xia, Xiwei ; Yang, Yilin ; Zhi, Feng
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2016-07, Vol.107 (7), p.899-907
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Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors
Author / Creator:Casillas, Andrea L. ; Chauhan, Shailender S. ; Toth, Rachel K. ; Sainz, Alva G. ; Clements, Amber N. ; Jensen, Corbin C. ; Langlais, Paul R. ; Miranti, Cindy K. ; Cress, Anne E. ; Warfel, Noel A.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-08, Vol.40 (32), p.5142-5152
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PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation
Author / Creator:Miyakawa, Kei ; Matsunaga, Satoko ; Yokoyama, Masaru ; Nomaguchi, Masako ; Kimura, Yayoi ; Nishi, Mayuko ; Kimura, Hirokazu ; Sato, Hironori ; Hirano, Hisashi ; Tamura, Tomohiko ; Akari, Hirofumi ; Miura, Tomoyuki ; Adachi, Akio ; Sawasaki, Tatsuya ; Yamamoto, Naoki ; Ryo, Akihide
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1844-12, Article 1844
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Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair
Author / Creator:Yun, Ying ; Wang, Min ; Guo, Shimeng ; Xie, Xin
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2890
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Serine/Threonine Protein Kinases as Attractive Targets for Anti-Cancer Drugs—An Innovative Approach to Ligand Tuning Using Combined Quantum Chemical Calculations, Molecular Docking, Molecular Dynamic...
Author / Creator:Latosińska, Magdalena ; Latosińska, Jolanta Natalia
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-07, Vol.29 (13), p.3199
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Pim1 promotes the maintenance of bone homeostasis by regulating osteoclast function
Author / Creator:Seo, Jeongin ; Ko, Ryeojin ; Kim, Minhee ; Seo, Jeongmin ; Lee, Hana ; Kim, Doyong ; Jeong, Woojin ; Kim, Han Sung ; Lee, Soo Young
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2025, 57(0), , pp.733-744
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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Author / Creator:Brasó-Maristany, Fara ; Filosto, Simone ; Catchpole, Steven ; Marlow, Rebecca ; Quist, Jelmar ; Francesch-Domenech, Erika ; Plumb, Darren A ; Zakka, Leila ; Gazinska, Patrycja ; Liccardi, Gianmaria ; Meier, Pascal ; Gris-Oliver, Albert ; Cheang, Maggie Chon U ; Perdrix-Rosell, Anna ; Shafat, Manar ; Noël, Elodie ; Patel, Nirmesh ; McEachern, Kristen ; Scaltriti, Maurizio ; Castel, Pau ; Noor, Farzana ; Buus, Richard ; Mathew, Sumi ; Watkins, Johnathan ; Serra, Violeta ; Marra, Pierfrancesco ; Grigoriadis, Anita ; Tutt, Andrew N
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2016-11, Vol.22 (11), p.1303-1313
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New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation
Author / Creator:Oyallon, Bruno ; Brachet-Botineau, Marie ; Logé, Cédric ; Robert, Thomas ; Bach, Stéphane ; Ibrahim, Sajida ; Raoul, William ; Croix, Cécile ; Berthelot, Pascal ; Guillon, Jean ; Pinaud, Noël ; Gouilleux, Fabrice ; Viaud-Massuard, Marie-Claude ; Denevault-Sabourin, Caroline
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.867
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The Dual PIM/FLT3 Inhibitor MEN1703 Combines Synergistically With Gilteritinib in FLT3‐ITD‐Mutant Acute Myeloid Leukaemia
Author / Creator:Zicari, Sonia ; Merlino, Giuseppe ; Paoli, Alessandro ; Fiascarelli, Alessio ; Tunici, Patrizia ; Bisignano, Diego ; Belli, Francesco ; Irrissuto, Clelia ; Talucci, Simone ; Cirigliano, Elena ; Iannitto, Maria Luisa ; Bigioni, Mario ; Bressan, Alessandro ; Brzózka, Krzysztof ; Ghiaur, Gabriel ; Bellarosa, Daniela ; Binaschi, Monica
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2024-12, Vol.28 (23), p.e70235-n/a
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Targeting Pim kinases in hematological cancers: molecular and clinical review
Author / Creator:Bellon, Marcia ; Nicot, Christophe
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2023-01, Vol.22 (1), p.18-18, Article 18
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Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts
Author / Creator:Santio, Niina M. ; Eerola, Sini K. ; Paatero, Ilkka ; Yli-Kauhaluoma, Jari ; Anizon, Fabrice ; Moreau, Pascale ; Tuomela, Johanna ; Härkönen, Pirkko ; Koskinen, Päivi J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0130340-e0130340
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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
Author / Creator:Horiuchi, Dai ; Camarda, Roman ; Zhou, Alicia Y ; Yau, Christina ; Momcilovic, Olga ; Balakrishnan, Sanjeev ; Corella, Alexandra N ; Eyob, Henok ; Kessenbrock, Kai ; Lawson, Devon A ; Marsh, Lindsey A ; Anderton, Brittany N ; Rohrberg, Julia ; Kunder, Ratika ; Bazarov, Alexey V ; Yaswen, Paul ; McManus, Michael T ; Rugo, Hope S ; Werb, Zena ; Goga, Andrei
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2016-11, Vol.22 (11), p.1321-1329
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Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation
Author / Creator:Din, Shabana ; Mason, Matthew ; Völkers, Mirko ; Johnson, Bevan ; Cottage, Christopher T. ; Wang, Zeping ; Joyo, Anya Y. ; Quijada, Pearl ; Erhardt, Peter ; Magnuson, Nancy S. ; Konstandin, Mathias H. ; Sussman, Mark A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.5969-5974
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Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements
Author / Creator:De Franchi, Enrico ; Schalon, Claire ; Messa, Mirko ; Onofri, Franco ; Benfenati, Fabio ; Rognan, Didier
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-08, Vol.5 (8), p.e12214-e12214
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Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer
Author / Creator:Luszczak, Sabina ; Simpson, Benjamin S. ; Stopka-Farooqui, Urszula ; Sathyadevan, Vignesh Krishna ; Echeverria, Lina M. Carmona ; Kumar, Christopher ; Costa, Helena ; Haider, Aiman ; Freeman, Alex ; Jameson, Charles ; Ratynska, Marzena ; Ben-Salha, Imen ; Sridhar, Ashwin ; Shaw, Greg ; Kelly, John D. ; Pye, Hayley ; Gately, Kathy A. ; Whitaker, Hayley C. ; Heavey, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.14380-12, Article 14380
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Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
Author / Creator:Shafie, Alaa ; Khan, Shama ; Batra, Sagar ; Anjum, Farah ; Mohammad, Taj ; Alam, Shoaib ; Yadav, Dharmendra Kumar ; Islam, Asimul ; Hassan, Md. Imtaiyaz
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-10, Vol.16 (10), p.e0258929
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Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system
Author / Creator:Eichmann, Anne ; Yuan, Li ; Bréant, Christiane ; Alitalo, Kari ; Koskinen, Päivi J
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 2000-02, Vol.19 (9), p.1215-1224
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Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential
Author / Creator:Cozza, Giorgio ; Girardi, Cristina ; Ranchio, Alessandro ; Lolli, Graziano ; Sarno, Stefania ; Orzeszko, Andrzej ; Kazimierczuk, Zygmunt ; Battistutta, Roberto ; Ruzzene, Maria ; Pinna, Lorenzo A.
Publisher:Basel: Springer Basel
Journal title:Cellular and molecular life sciences : CMLS, 2014-08, Vol.71 (16), p.3173-3185
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Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients
Author / Creator:Ntzifa, Aliki ; Strati, Areti ; Kallergi, Galatea ; Kotsakis, Athanasios ; Georgoulias, Vassilis ; Lianidou, Evi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.2313-2313, Article 2313
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Showing 1 to 20 of 230 results

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Pim-1 regulates cardiomyocyte survival downstream of Akt

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MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

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Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

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PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation

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Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair

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Serine/Threonine Protein Kinases as Attractive Targets for Anti-Cancer Drugs—An Innovative Approach to Ligand Tuning Using Combined Quantum Chemical Calculations, Molecular Docking, Molecular Dynamic...

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Pim1 promotes the maintenance of bone homeostasis by regulating osteoclast function

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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

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New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

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The Dual PIM/FLT3 Inhibitor MEN1703 Combines Synergistically With Gilteritinib in FLT3‐ITD‐Mutant Acute Myeloid Leukaemia

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Targeting Pim kinases in hematological cancers: molecular and clinical review

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Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression

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Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation

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Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements

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Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer

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Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

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Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system

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Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

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Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients

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