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249 results for Pyrrolidines+-+chemistry

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ArticlesPeer ReviewedFull Text
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
Author / Creator:Ma, Chunlong ; Sacco, Michael Dominic ; Hurst, Brett ; Townsend, Julia Alma ; Hu, Yanmei ; Szeto, Tommy ; Zhang, Xiujun ; Tarbet, Bart ; Marty, Michael Thomas ; Chen, Yu ; Wang, Jun
Publisher:Singapore: Springer Singapore
Journal title:Cell research, 2020-08, Vol.30 (8), p.678-692
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Deconstructive diversification of cyclic amines
Author / Creator:Roque, Jose B. ; Kuroda, Yusuke ; Göttemann, Lucas T. ; Sarpong, Richmond
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-12, Vol.564 (7735), p.244-248
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Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Author / Creator:Vuong, Wayne ; Khan, Muhammad Bashir ; Fischer, Conrad ; Arutyunova, Elena ; Lamer, Tess ; Shields, Justin ; Saffran, Holly A. ; McKay, Ryan T. ; van Belkum, Marco J. ; Joyce, Michael A. ; Young, Howard S. ; Tyrrell, D. Lorne ; Vederas, John C. ; Lemieux, M. Joanne
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4282-8, Article 4282
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Application of Ionic Liquids in Electrochemistry—Recent Advances
Author / Creator:Tiago, Gonçalo A. O. ; Matias, Inês A. S. ; Ribeiro, Ana P. C. ; Martins, Luísa M. D. R. S.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5812
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Complex N-Heterocycle Synthesis via Iron-Catalyzed, Direct C–H Bond Amination
Author / Creator:Hennessy, Elisabeth T. ; Betley, Theodore A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6132), p.591-595
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Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis
Author / Creator:Talpaz, Moshe ; Kiladjian, Jean-Jacques
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-01, Vol.35 (1), p.1-17
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Nanobody-enabled monitoring of kappa opioid receptor states
Author / Creator:Che, Tao ; English, Justin ; Krumm, Brian E. ; Kim, Kuglae ; Pardon, Els ; Olsen, Reid H. J. ; Wang, Sheng ; Zhang, Shicheng ; Diberto, Jeffrey F. ; Sciaky, Noah ; Carroll, F. Ivy ; Steyaert, Jan ; Wacker, Daniel ; Roth, Bryan L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-03, Vol.11 (1), p.1145-1145, Article 1145
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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Author / Creator:Dampalla, Chamandi S. ; Zheng, Jian ; Perera, Krishani Dinali ; Wong, Lok-Yin Roy ; Meyerholz, David K. ; Nguyen, Harry Nhat ; Kashipathy, Maithri M. ; Battaile, Kevin P. ; Lovell, Scott ; Kim, Yunjeong ; Perlman, Stanley ; Groutas, William C. ; Chang, Kyeong-Ok
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1-8
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Fedratinib: First Approval
Author / Creator:Blair, Hannah A.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2019-10, Vol.79 (15), p.1719-1725
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Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products
Author / Creator:Baumann, Michael H ; Partilla, John S ; Lehner, Kurt R ; Thorndike, Eric B ; Hoffman, Alexander F ; Holy, Marion ; Rothman, Richard B ; Goldberg, Steven R ; Lupica, Carl R ; Sitte, Harald H ; Brandt, Simon D ; Tella, Srihari R ; Cozzi, Nicholas V ; Schindler, Charles W
Publisher:Basingstoke: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2013-03, Vol.38 (4), p.552-562
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Role of Surfactants on Release Performance of Amorphous Solid Dispersions of Ritonavir and Copovidone
Author / Creator:Indulkar, Anura S. ; Lou, Xiaochun ; Zhang, Geoff G. Z. ; Taylor, Lynne S.
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2022-02, Vol.39 (2), p.381-397
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Small-molecule WNK inhibition regulates cardiovascular and renal function
Author / Creator:Yamada, Ken ; Park, Hyi-Man ; Rigel, Dean F ; DiPetrillo, Keith ; Whalen, Erin J ; Anisowicz, Anthony ; Beil, Michael ; Berstler, James ; Brocklehurst, Cara Emily ; Burdick, Debra A ; Caplan, Shari L ; Capparelli, Michael P ; Chen, Guanjing ; Chen, Wei ; Dale, Bethany ; Deng, Lin ; Fu, Fumin ; Hamamatsu, Norio ; Harasaki, Kouki ; Herr, Tracey ; Hoffmann, Peter ; Hu, Qi-Ying ; Huang, Waan-Jeng ; Idamakanti, Neeraja ; Imase, Hidetomo ; Iwaki, Yuki ; Jain, Monish ; Jeyaseelan, Jey ; Kato, Mitsunori ; Kaushik, Virendar K ; Kohls, Darcy ; Kunjathoor, Vidya ; LaSala, Daniel ; Lee, Jongchan ; Liu, Jing ; Luo, Yang ; Ma, Fupeng ; Mo, Ruowei ; Mowbray, Sarah ; Mogi, Muneto ; Ossola, Flavio ; Pandey, Pramod ; Patel, Sejal J ; Raghavan, Swetha ; Salem, Bahaa ; Shanado, Yuka H ; Trakshel, Gary M ; Turner, Gordon ; Wakai, Hiromichi ; Wang, Chunhua ; Weldon, Stephen ; Wielicki, Jennifer B ; Xie, Xiaoling ; Xu, Lingfei ; Yagi, Yukiko I ; Yasoshima, Kayo ; Yin, Jianning ; Yowe, David ; Zhang, Ji-Hu ; Zheng, Gang ; Monovich, Lauren
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-11, Vol.12 (11), p.896-898
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A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation
Author / Creator:Rakib, Ahmed ; Nain, Zulkar ; Sami, Saad Ahmed ; Mahmud, Shafi ; Islam, Ashiqul ; Ahmed, Shahriar ; Siddiqui, Adnan Bin Faisul ; Babu, S M Omar Faruque ; Hossain, Payar ; Shahriar, Asif ; Nainu, Firzan ; Emran, Talha Bin ; Simal-Gandara, Jesus
Publisher:England: Oxford University Press
Journal title:Briefings in bioinformatics, 2021-03, Vol.22 (2), p.1476-1498
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Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer
Author / Creator:Lainé, Muriel ; Fanning, Sean W. ; Chang, Ya-Fang ; Green, Bradley ; Greene, Marianne E. ; Komm, Barry ; Kurleto, Justyna D. ; Phung, Linda ; Greene, Geoffrey L.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2021-05, Vol.23 (1), p.54-54, Article 54
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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells
Author / Creator:Barsyte-Lovejoy, Dalia ; Li, Fengling ; Oudhoff, Menno J. ; Tatlock, John H. ; Dong, Aiping ; Zeng, Hong ; Wu, Hong ; Freeman, Spencer A. ; Schapira, Matthieu ; Senisterra, Guillermo A. ; Kuznetsova, Ekaterina ; Marcellus, Richard ; Allali-Hassani, Abdellah ; Kennedy, Steven ; Lambert, Jean-Philippe ; Couzens, Amber L. ; Aman, Ahmed ; Gingras, Anne-Claude ; Al-Awar, Rima ; Fish, Paul V. ; Gerstenberger, Brian S. ; Roberts, Lee ; Benn, Caroline L. ; Grimley, Rachel L. ; Braam, Mitchell J. S. ; Rossi, Fabio M. V. ; Sudol, Marius ; Brown, Peter J. ; Bunnage, Mark E. ; Owen, Dafydd R. ; Zaph, Colby ; Vedadi, Masoud ; Arrowsmith, Cheryl H.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (35), p.12853-12858
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Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates
Author / Creator:Bagán, Andrea ; López-Ruiz, Alba ; Abás, Sònia ; Molins, Elies ; Pérez, Belén ; Muneta-Arrate, Itziar ; Callado, Luis F. ; Escolano, Carmen
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-05, Vol.30 (9), p.2078
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Improving Water Permeability of Hydrophilic PVDF Membrane Prepared via Blending with Organic and Inorganic Additives for Humic Acid Separation
Author / Creator:Arahman, Nasrul ; Mulyati, Sri ; Fahrina, Afrillia ; Muchtar, Syawaliah ; Yusuf, Mukramah ; Takagi, Ryosuke ; Matsuyama, Hideto ; Nordin, Nik Abdul Hadi ; Bilad, Muhammad Roil
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-11, Vol.24 (22), p.4099
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Towards Metabolic Organic Radical Contrast Agents (mORCAs) for Magnetic Resonance Imaging
Author / Creator:Zhang, Shuyang ; Dhakal, Sabina ; Curtis, Evan ; Miller, Hunter ; Paletta, Joseph T. ; Gee, Connor ; Rajca, Suchada ; Kievit, Forrest ; Rajca, Andrzej
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-04, Vol.30 (7), p.1581
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The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning
Author / Creator:Decherchi, Sergio ; Berteotti, Anna ; Bottegoni, Giovanni ; Rocchia, Walter ; Cavalli, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-01, Vol.6 (1), p.6155-6155, Article 6155
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Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity
Author / Creator:Boudriga, Sarra ; Haddad, Saoussen ; Murugaiyah, Vikneswaran ; Askri, Moheddine ; Knorr, Michael ; Strohmann, Carsten ; Golz, Christopher
Publisher:Switzerland: MDPI
Journal title:Molecules (Basel, Switzerland), 2020-04, Vol.25 (8), p.1963
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Showing 1 to 20 of 249 results

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Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

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Deconstructive diversification of cyclic amines

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Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

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Application of Ionic Liquids in Electrochemistry—Recent Advances

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Complex N-Heterocycle Synthesis via Iron-Catalyzed, Direct C–H Bond Amination

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Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis

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Nanobody-enabled monitoring of kappa opioid receptor states

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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

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Fedratinib: First Approval

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Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products

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Role of Surfactants on Release Performance of Amorphous Solid Dispersions of Ritonavir and Copovidone

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Small-molecule WNK inhibition regulates cardiovascular and renal function

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A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation

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Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer

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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

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Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates

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Improving Water Permeability of Hydrophilic PVDF Membrane Prepared via Blending with Organic and Inorganic Additives for Humic Acid Separation

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Towards Metabolic Organic Radical Contrast Agents (mORCAs) for Magnetic Resonance Imaging

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The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning

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Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity

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