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ArticlesPeer ReviewedFull Text
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists
Author / Creator:Zheng, Yi ; Qin, Ling ; Zacarías, Natalia V. Ortiz ; de Vries, Henk ; Han, Gye Won ; Gustavsson, Martin ; Dabros, Marta ; Zhao, Chunxia ; Cherney, Robert J. ; Carter, Percy ; Stamos, Dean ; Abagyan, Ruben ; Cherezov, Vadim ; Stevens, Raymond C. ; IJzerman, Adriaan P. ; Heitman, Laura H. ; Tebben, Andrew ; Kufareva, Irina ; Handel, Tracy M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-12, Vol.540 (7633), p.458-461
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Dolutegravir in Antiretroviral-Experienced Patients With Raltegravir- and/or Elvitegravir-Resistant HIV-1: 24-Week Results of the Phase III VIKING-3 Study
Author / Creator:Castagna, Antonella ; Maggiolo, Franco ; Penco, Giovanni ; Wright, David ; Mills, Anthony ; Grossberg, Robert ; Molina, Jean-Michel ; Chas, Julie ; Durant, Jacques ; Moreno, Santiago ; Doroana, Manuela ; Ait-Khaled, Mounir ; Huang, Jenny ; Min, Sherene ; Song, Ivy ; Vavro, Cindy ; Nichols, Garrett ; Yeo, Jane M.
Publisher:Oxford: Oxford University Press
Journal title:The Journal of infectious diseases, 2014-08, Vol.210 (3), p.354-362
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Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators
Author / Creator:Buhr, Ethan D ; Yoo, Seung-Hee ; Takahashi, Joseph S
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-10, Vol.330 (6002), p.379-385
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Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids
Author / Creator:Trujillo, Cleber A ; Adams, Jason W ; Negraes, Priscilla D ; Carromeu, Cassiano ; Tejwani, Leon ; Acab, Allan ; Tsuda, Ben ; Thomas, Charles A ; Sodhi, Neha ; Fichter, Katherine M ; Romero, Sarah ; Zanella, Fabian ; Sejnowski, Terrence J ; Ulrich, Henning ; Muotri, Alysson R
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-01, Vol.13 (1), p.e12523-n/a
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Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study
Author / Creator:Eron, Joseph J. ; Clotet, Bonaventura ; Durant, Jacques ; Katlama, Christine ; Kumar, Princy ; Lazzarin, Adriano ; Poizot-Martin, Isabelle ; Richmond, Gary ; Soriano, Vincent ; Ait-Khaled, Mounir ; Fujiwara, Tamio ; Huang, Jenny ; Min, Sherene ; Vavro, Cindy ; Yeo, Jane
Publisher:Oxford: Oxford University Press
Journal title:The Journal of infectious diseases, 2013-03, Vol.207 (5), p.740-748
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Effects of antiepileptic drugs on cortical excitability in humans: A TMS‐EMG and TMS‐EEG study
Author / Creator:Darmani, Ghazaleh ; Bergmann, Til O. ; Zipser, Carl ; Baur, David ; Müller‐Dahlhaus, Florian ; Ziemann, Ulf
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:Human brain mapping, 2019-03, Vol.40 (4), p.1276-1289
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Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling
Author / Creator:Liu, Chun-Hua ; Gong, Zheng ; Liang, Zong-Lai ; Liu, Zhi-Xin ; Yang, Fan ; Sun, Yu-Jing ; Ma, Ming-Liang ; Wang, Yi-Jing ; Ji, Chao-Ran ; Wang, Yu-Hong ; Wang, Mei-Jie ; Cui, Fu-Ai ; Lin, Amy ; Zheng, Wen-Shuai ; He, Dong-Fang ; Qu, Chang-xiu ; Xiao, Peng ; Liu, Chuan-Yong ; Thomsen, Alex R. B. ; Joseph Cahill, Thomas ; Kahsai, Alem W. ; Yi, Fan ; Xiao, Kun-Hong ; Xue, Tian ; Zhou, Zhuan ; Yu, Xiao ; Sun, Jin-Peng
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14335-17, Article 14335
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Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
Author / Creator:Lauinger, Linda ; Li, Jing ; Shostak, Anton ; Cemel, Ibrahim Avi ; Ha, Nati ; Zhang, Yaru ; Merkl, Philipp E ; Obermeyer, Simon ; Stankovic-Valentin, Nicolas ; Schafmeier, Tobias ; Wever, Walter J ; Bowers, Albert A ; Carter, Kyle P ; Palmer, Amy E ; Tschochner, Herbert ; Melchior, Frauke ; Deshaies, Raymond J ; Brunner, Michael ; Diernfellner, Axel
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-07, Vol.13 (7), p.709-714
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Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial
Author / Creator:Lennox, Jeffrey L, Prof ; DeJesus, Edwin, MD ; Lazzarin, Adriano, Prof ; Pollard, Richard B, Prof ; Madruga, Jose Valdez Ramalho, MD ; Berger, Daniel S, MD ; Zhao, Jing, PhD ; Xu, Xia, PhD ; Williams-Diaz, Angela, BS ; Rodgers, Anthony J, MS ; Barnard, Richard JO, PhD ; Miller, Michael D, PhD ; DiNubile, Mark J, MD ; Nguyen, Bach-Yen, MD ; Leavitt, Randi, MD ; Sklar, Peter, Dr
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2009-09, Vol.374 (9692), p.796-806
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HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
Author / Creator:J Buzón, Maria ; Massanella, Marta ; Llibre, Josep M ; Esteve, Anna ; Dahl, Viktor ; Puertas, Maria C ; Gatell, Josep M ; Domingo, Pere ; Paredes, Roger ; Sharkey, Mark ; Palmer, Sarah ; Stevenson, Mario ; Clotet, Bonaventura ; Blanco, Julià ; Martinez-Picado, Javier
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2010-04, Vol.16 (4), p.460-465
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ArticlesPeer ReviewedFull Text
Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis
Author / Creator:Gulbransen, Brian D ; Bashashati, Mohammad ; Hirota, Simon A ; Gui, Xianyong ; Roberts, Jane A ; MacDonald, Justin A ; Muruve, Daniel A ; McKay, Derek M ; Beck, Paul L ; Mawe, Gary M ; Thompson, Roger J ; Sharkey, Keith A
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-04, Vol.18 (4), p.600-604
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ArticlesPeer ReviewedFull Text
KNK437 restricts the growth and metastasis of colorectal cancer via targeting DNAJA1/CDC45 axis
Author / Creator:Yang, Shaoshan ; Ren, Xiaoli ; Liang, Yunshi ; Yan, Yongrong ; Zhou, Yangshu ; Hu, Jinlong ; Wang, Zhizhi ; Song, Fuyao ; Wang, Feifei ; Liao, Wangjun ; Liao, Wenting ; Ding, Yanqing ; Liang, Li
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-01, Vol.39 (2), p.249-261
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HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration
Author / Creator:Cooper, Arik ; García, Mayra ; Petrovas, Constantinos ; Yamamoto, Takuya ; Koup, Richard A. ; Nabel, Gary J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-06, Vol.498 (7454), p.376-379
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Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance
Author / Creator:Hare, Stephen ; Vos, Ann M. ; Clayton, Reginald F. ; Thuring, Jan W. ; Cummings, Maxwell D. ; Cherepanov, Peter ; Coffin, John M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (46), p.20057-20062
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SF2312 is a natural phosphonate inhibitor of enolase
Author / Creator:Leonard, Paul G ; Satani, Nikunj ; Maxwell, David ; Lin, Yu-Hsi ; Hammoudi, Naima ; Peng, Zhenghong ; Pisaneschi, Federica ; Link, Todd M ; Lee, Gilbert R ; Sun, Duoli ; Prasad, Basvoju A Bhanu ; Di Francesco, Maria Emilia ; Czako, Barbara ; Asara, John M ; Wang, Y Alan ; Bornmann, William ; DePinho, Ronald A ; Muller, Florian L
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-12, Vol.12 (12), p.1053-1058
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The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms
Author / Creator:Jiang, Minghua ; Chen, Senhua ; Li, Jing ; Liu, Lan
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2020-02, Vol.18 (2), p.114
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The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial
Author / Creator:Gandhi, Rajesh T. ; Zheng, Lu ; Bosch, Ronald J. ; Chan, Ellen S. ; Margolis, David M. ; Read, Sarah ; Kallungal, Beatrice ; Palmer, Sarah ; Medvik, Kathy ; Lederman, Michael M. ; Alatrakchi, Nadia ; Jacobson, Jeffrey M. ; Wiegand, Ann ; Kearney, Mary ; Coffin, John M. ; Mellors, John W. ; Eron, Joseph J.
Publisher:United States: Public Library of Science
Journal title:PLOS MEDICINE, 2010-08, Vol.7 (8), p.e1000321
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Zopfiellamides C and D, New Decalin-Type Tetramic Acid Derivatives from the Marine-Derived Fungus Aspergillus sp. NF666
Author / Creator:Jiao, Fangwen ; Liu, Tianyu ; Wang, Kaiwei ; Li, Shuai ; Jiao, Ruihua ; Lin, Wei
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-03, Vol.30 (7), p.1502
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HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications
Author / Creator:Blanco, Jose-Luis ; Varghese, Vici ; Rhee, Soo-Yon ; Gatell, Jose M. ; Shafer, Robert W.
Publisher:Oxford: Oxford University Press
Journal title:The Journal of infectious diseases, 2011-05, Vol.203 (9), p.1204-1214
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CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression
Author / Creator:Chun-Hao, Tsai ; Chao-Ju, Chen ; Chi-Li, Gong ; Shan-Chi, Liu ; Po-Chun, Chen ; Chien-Chung, Huang ; Sung-Lin, Hu ; Shih-Wei, Wang ; Tang Chih-Hsin
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2021-09, Vol.12 (9)
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Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

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Dolutegravir in Antiretroviral-Experienced Patients With Raltegravir- and/or Elvitegravir-Resistant HIV-1: 24-Week Results of the Phase III VIKING-3 Study

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Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

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Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids

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Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study

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Effects of antiepileptic drugs on cortical excitability in humans: A TMS‐EMG and TMS‐EEG study

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Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling

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Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

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Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial

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HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

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Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis

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KNK437 restricts the growth and metastasis of colorectal cancer via targeting DNAJA1/CDC45 axis

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HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

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Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance

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SF2312 is a natural phosphonate inhibitor of enolase

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The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms

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The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial

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Zopfiellamides C and D, New Decalin-Type Tetramic Acid Derivatives from the Marine-Derived Fungus Aspergillus sp. NF666

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HIV-1 Integrase Inhibitor Resistance and Its Clinical Implications

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CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression

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