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147 results for Receptors,+Interleukin-7+-+metabolism

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ArticlesPeer ReviewedFull Text
Flip the coin: IL-7 and IL-7R in health and disease
Author / Creator:Barata, João ; Durum, Scott K. ; Seddon, Benedict
Publisher:New York: Springer Nature
Journal title:Nature immunology, 2019-12, Vol.20 (12), p.1584-1593
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IL-17 receptor–based signaling and implications for disease
Author / Creator:Li, Xiaoxia ; Bechara, Rami ; Zhao, Junjie ; McGeachy, Mandy J. ; Gaffen, Sarah L.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-12, Vol.20 (12), p.1594-1602
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IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells
Author / Creator:Huang, Yuefeng ; Guo, Liying ; Qiu, Jin ; Chen, Xi ; Hu-Li, Jane ; Siebenlist, Ulrich ; Williamson, Peter R ; Urban, Jr, Joseph F ; Paul, William E
Publisher:United States
Journal title:Nature immunology, 2015-02, Vol.16 (2), p.161-169
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Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells
Author / Creator:Rodrigues, Patrick Fernandes ; Alberti-Servera, Llucia ; Eremin, Anna ; Grajales-Reyes, Gary E. ; Ivanek, Robert ; Tussiwand, Roxane
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-07, Vol.19 (7), p.711-722
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ArticlesPeer ReviewedFull Text
IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis
Author / Creator:Gracey, Eric ; Qaiyum, Zoya ; Almaghlouth, Ibrahim ; Lawson, Daeria ; Karki, Susan ; Avvaru, Naga ; Zhang, Zhenbo ; Yao, Yuchen ; Ranganathan, Vidya ; Baglaenko, Yuriy ; Inman, Robert D
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2016-12, Vol.75 (12), p.2124-2132
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T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
Author / Creator:McKinney, Eoin F. ; Lee, James C. ; Jayne, David R. W. ; Lyons, Paul A. ; Smith, Kenneth G. C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-07, Vol.523 (7562), p.612-616
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A human memory T cell subset with stem cell–like properties
Author / Creator:Gattinoni, Luca ; Lugli, Enrico ; Ji, Yun ; Pos, Zoltan ; Paulos, Chrystal M ; Quigley, Máire F ; Almeida, Jorge R ; Gostick, Emma ; Yu, Zhiya ; Carpenito, Carmine ; Wang, Ena ; Douek, Daniel C ; Price, David A ; June, Carl H ; Marincola, Francesco M ; Roederer, Mario ; Restifo, Nicholas P
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2011-10, Vol.17 (10), p.1290-1297
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IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease
Author / Creator:Belarif, Lyssia ; Danger, Richard ; Kermarrec, Laetitia ; Nerrière-Daguin, Véronique ; Pengam, Sabrina ; Durand, Tony ; Mary, Caroline ; Kerdreux, Elise ; Gauttier, Vanessa ; Kucik, Aneta ; Thepenier, Virginie ; Martin, Jerome C. ; Chang, Christie ; Rahman, Adeeb ; Guen, Nina Salabert-Le ; Braudeau, Cécile ; Abidi, Ahmed ; David, Grégoire ; Malard, Florent ; Takoudju, Celine ; Martinet, Bernard ; Gérard, Nathalie ; Neveu, Isabelle ; Neunlist, Michel ; Coron, Emmanuel ; MacDonald, Thomas T. ; Desreumaux, Pierre ; Mai, Hoa-Le ; Le Bas-Bernardet, Stephanie ; Mosnier, Jean-François ; Merad, Miriam ; Josien, Régis ; Brouard, Sophie ; Soulillou, Jean-Paul ; Blancho, Gilles ; Bourreille, Arnaud ; Naveilhan, Philippe ; Vanhove, Bernard ; Poirier, Nicolas
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-05, Vol.129 (5), p.1910-1925
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ArticlesPeer ReviewedFull Text
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
Author / Creator:Verstraete, Kenneth ; Peelman, Frank ; Braun, Harald ; Lopez, Juan ; Van Rompaey, Dries ; Dansercoer, Ann ; Vandenberghe, Isabel ; Pauwels, Kris ; Tavernier, Jan ; Lambrecht, Bart N. ; Hammad, Hamida ; De Winter, Hans ; Beyaert, Rudi ; Lippens, Guy ; Savvides, Savvas N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-04, Vol.8 (1), p.14937-14937, Article 14937
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ArticlesPeer ReviewedFull Text
NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
Author / Creator:Wang, Hongfang ; Zang, Chongzhi ; Taing, Len ; Arnett, Kelly L. ; Wong, Yinling Joey ; Pear, Warren S. ; Blacklow, Stephen C. ; Liu, Shirley ; Aster, Jon C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (2), p.705-710
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ArticlesPeer ReviewedFull Text
Harnessing the biology of IL-7 for therapeutic application
Author / Creator:Mackall, Crystal L. ; Fry, Terry J. ; Gress, Ronald E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2011-05, Vol.11 (5), p.330-342
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ArticlesPeer ReviewedFull Text
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
Author / Creator:Shi, Lewis Zhichang ; Fu, Tihui ; Guan, Baoxiang ; Chen, Jianfeng ; Blando, Jorge M. ; Allison, James P. ; Xiong, Liangwen ; Subudhi, Sumit K. ; Gao, Jianjun ; Sharma, Padmanee
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12335-12335, Article 12335
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ArticlesPeer ReviewedFull Text
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment
Author / Creator:Zhong, Chao ; Cui, Kairong ; Wilhelm, Christoph ; Hu, Gangqing ; Mao, Kairui ; Belkaid, Yasmine ; Zhao, Keji ; Zhu, Jinfang
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-02, Vol.17 (2), p.169-178
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Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
Author / Creator:Zenatti, Priscila P ; Ribeiro, Daniel ; Li, Wenqing ; Zuurbier, Linda ; Silva, Milene C ; Paganin, Maddalena ; Tritapoe, Julia ; Hixon, Julie A ; Silveira, André B ; Cardoso, Bruno A ; Sarmento, Leonor M ; Correia, Nádia ; Toribio, Maria L ; Kobarg, Jörg ; Horstmann, Martin ; Pieters, Rob ; Brandalise, Silvia R ; Ferrando, Adolfo A ; Meijerink, Jules P ; Durum, Scott K ; Yunes, J Andrés ; Barata, João T
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-10, Vol.43 (10), p.932-939
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ArticlesPeer ReviewedFull Text
Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease
Author / Creator:Yoon, Jae-Won ; Kim, Kyung Min ; Cho, Sookyung ; Cho, Min-Ji ; Park, Seonjun ; Hwang, Daehee ; Kim, Hye Ryun ; Park, Sung Ho ; Cho, Jae-Ho ; Jeong, Hyobin ; Choi, Je-Min
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1962-16, Article 1962
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ArticlesPeer ReviewedFull Text
Macrophages are the primary effector cells in IL-7-induced arthritis
Author / Creator:Kim, Seung-jae ; Chang, Huan J. ; Volin, Michael V. ; Umar, Sadiq ; Van Raemdonck, Katrien ; Chevalier, Aimee ; Palasiewicz, Karol ; Christman, John W. ; Volkov, Suncica ; Arami, Shiva ; Maz, Mehrdad ; Mehta, Anjali ; Zomorrodi, Ryan K. ; Fox, David A. ; Sweiss, Nadera ; Shahrara, Shiva
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2020-07, Vol.17 (7), p.728-740
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A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
Author / Creator:Akkapeddi, Padma ; Fragoso, Rita ; Hixon, Julie A. ; Ramalho, Ana Sofia ; Oliveira, Mariana L. ; Carvalho, Tânia ; Gloger, Andreas ; Matasci, Mattia ; Corzana, Francisco ; Durum, Scott K. ; Neri, Dario ; Bernardes, Gonçalo J. L. ; Barata, João T.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2019-09, Vol.33 (9), p.2155-2168
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Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice
Author / Creator:Thomas, Kerri R. ; Allenspach, Eric J. ; Camp, Nathan D. ; Wray-Dutra, Michelle N. ; Khim, Socheath ; Zielinska-Kwiatkowska, Anna ; Timms, Andrew E. ; Loftus, Joseph P. ; Liggitt, H. Denny ; Georgopoulos, Katia ; Tasian, Sarah K. ; James, Richard G. ; Rawlings, David J.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-01, Vol.36 (1), p.42-57
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MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia
Author / Creator:Canté-Barrett, K ; Spijkers-Hagelstein, J A P ; Buijs-Gladdines, J G C A M ; Uitdehaag, J C M ; Smits, W K ; van der Zwet, J ; Buijsman, R C ; Zaman, G J R ; Pieters, R ; Meijerink, J P P
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2016-09, Vol.30 (9), p.1832-1843
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APOE ε4–associated downregulation of the IL‐7/IL‐7R pathway in effector memory T cells: Implications for Alzheimer's disease
Author / Creator:Zhang, Ying‐Jie ; Cheng, Yan ; Tang, Hai‐Liang ; Yue, Qi ; Cai, Xin‐Yi ; Lu, Zhi‐Jie ; Hao, Yi‐Xuan ; Dai, An‐Xiang ; Hou, Ting ; Liu, Hao‐Xin ; Kong, Nan ; Ji, Xiao‐Yu ; Lu, Chang‐Hao ; Xu, Sheng‐Liang ; Huang, Kai ; Zeng, Xin ; Wen, Ya‐Qi ; Ma, Wan‐Yin ; Guan, Ji‐Tian ; Lin, Yan ; Zheng, Wen‐Bin ; Pan, Hui ; Wu, Jie ; Wu, Ren‐Hua ; Wei, Nai‐Li
Publisher:United States: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-09, Vol.20 (9), p.6441-6455
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Flip the coin: IL-7 and IL-7R in health and disease

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IL-17 receptor–based signaling and implications for disease

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IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells

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Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

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IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis

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T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

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A human memory T cell subset with stem cell–like properties

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IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease

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Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

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NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers

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Harnessing the biology of IL-7 for therapeutic application

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Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy

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Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

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Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

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Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease

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Macrophages are the primary effector cells in IL-7-induced arthritis

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A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia

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Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice

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MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

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APOE ε4–associated downregulation of the IL‐7/IL‐7R pathway in effector memory T cells: Implications for Alzheimer's disease

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