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164 results for Receptors,+Notch+-+antagonists+

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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
Author / Creator:Takebe, Naoko ; Miele, Lucio ; Harris, Pamela Jo ; Jeong, Woondong ; Bando, Hideaki ; Kahn, Michael ; Yang, Sherry X. ; Ivy, S. Percy
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2015-08, Vol.12 (8), p.445-464
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Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
Author / Creator:Lim, Jing Shan ; Ibaseta, Alvaro ; Fischer, Marcus M. ; Cancilla, Belinda ; O’Young, Gilbert ; Cristea, Sandra ; Luca, Vincent C. ; Yang, Dian ; Jahchan, Nadine S. ; Hamard, Cécile ; Antoine, Martine ; Wislez, Marie ; Kong, Christina ; Cain, Jennifer ; Liu, Yu-Wang ; Kapoun, Ann M. ; Garcia, K. Christopher ; Hoey, Timothy ; Murriel, Christopher L. ; Sage, Julien
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-05, Vol.545 (7654), p.360-364
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Therapeutic modulation of Notch signalling — are we there yet?
Author / Creator:Andersson, Emma R. ; Lendahl, Urban
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2014-05, Vol.13 (5), p.357-378
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Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
Author / Creator:van Es, Johan H. ; Sato, Toshiro ; van de Wetering, Marc ; Lyubimova, Anna ; Yee Nee, Annie Ng ; Gregorieff, Alex ; Sasaki, Nobuo ; Zeinstra, Laura ; van den Born, Maaike ; Korving, Jeroen ; Martens, Anton C. M. ; Barker, Nick ; van Oudenaarden, Alexander ; Clevers, Hans
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-10, Vol.14 (10), p.1099-1104
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Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients
Author / Creator:Fendler, Annika ; Bauer, Daniel ; Busch, Jonas ; Jung, Klaus ; Wulf-Goldenberg, Annika ; Kunz, Severine ; Song, Kun ; Myszczyszyn, Adam ; Elezkurtaj, Sefer ; Erguen, Bettina ; Jung, Simone ; Chen, Wei ; Birchmeier, Walter
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.929-929, Article 929
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COVID-19 in the heart and the lungs: could we “Notch” the inflammatory storm?
Author / Creator:Rizzo, Paola ; Vieceli Dalla Sega, Francesco ; Fortini, Francesca ; Marracino, Luisa ; Rapezzi, Claudio ; Ferrari, Roberto
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2020-04, Vol.115 (3), p.31, Article 31
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Neurogenic radial glia in the outer subventricular zone of human neocortex
Author / Creator:Hansen, David V. ; Lui, Jan H. ; Parker, Philip R. L. ; Kriegstein, Arnold R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-03, Vol.464 (7288), p.554-561
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Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH
Author / Creator:Wasson, Christopher W ; Abignano, Giuseppina ; Hermes, Heidi ; Malaab, Maya ; Ross, Rebecca L ; Jimenez, Sergio A ; Chang, Howard Y ; Feghali-Bostwick, Carol A ; del Galdo, Francesco
Publisher:United States: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2020-04, Vol.79 (4), p.507-517
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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway
Author / Creator:Li, Wenyan ; Wu, Jingfang ; Yang, Jianming ; Sun, Shan ; Chai, Renjie ; Chen, Zheng-Yi ; Li, Huawei
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (1), p.166-171
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Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
Author / Creator:Takebe, Naoko ; Harris, Pamela J. ; Warren, Ronald Q. ; Ivy, S. Percy
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2011-02, Vol.8 (2), p.97-106
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Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway
Author / Creator:Song, Bao-quan ; Chi, Ying ; Li, Xue ; Du, Wen-jing ; Han, Zhi-Bo ; Tian, Jian-jian ; Li, Juan-juan ; Chen, Fang ; Wu, He-he ; Han, Li-xin ; Lu, Shi-hong ; Zheng, Yi-zhou ; Han, Zhong-chao
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2015-01, Vol.36 (5), p.1991-2002
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Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma
Author / Creator:Mizutari, Kunio ; Fujioka, Masato ; Hosoya, Makoto ; Bramhall, Naomi ; Okano, Hirotaka James ; Okano, Hideyuki ; Edge, Albert S.B.
Publisher:United States: Elsevier Inc
Journal title:Neuron (Cambridge, Mass.), 2013-01, Vol.77 (1), p.58-69
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Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors
Author / Creator:Li, Wenlin ; Sun, Woong ; Zhang, Yu ; Wei, Wanguo ; Ambasudhan, Rajesh ; Xia, Peng ; Talantova, Maria ; Lin, Tongxiang ; Kim, Janghwan ; Wang, Xiaolei ; Kim, Woon Ryoung ; Lipton, Stuart A ; Zhang, Kang ; Ding, Sheng
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (20), p.8299-8304
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A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma
Author / Creator:Cook, Natalie ; Basu, Bristi ; Smith, Donna-Michelle ; Gopinathan, Aarthi ; Evans, Jeffry ; Steward, William P ; Palmer, Daniel ; Propper, David ; Venugopal, Balaji ; Hategan, Mirela ; Anthoney, D Alan ; Hampson, Lisa V ; Nebozhyn, Michael ; Tuveson, David ; Farmer-Hall, Hayley ; Turner, Helen ; McLeod, Robert ; Halford, Sarah ; Jodrell, Duncan
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2018-03, Vol.118 (6), p.793-801
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High mitogenic stimulation arrests angiogenesis
Author / Creator:Pontes-Quero, Samuel ; Fernández-Chacón, Macarena ; Luo, Wen ; Lunella, Federica Francesca ; Casquero-Garcia, Verónica ; Garcia-Gonzalez, Irene ; Hermoso, Ana ; Rocha, Susana F. ; Bansal, Mayank ; Benedito, Rui
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2016-2016, Article 2016
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Notch controls the survival of memory CD4+ T cells by regulating glucose uptake
Author / Creator:Maekawa, Yoichi ; Ishifune, Chieko ; Tsukumo, Shin-ichi ; Hozumi, Katsuto ; Yagita, Hideo ; Yasutomo, Koji
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-01, Vol.21 (1), p.55-61
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Therapeutic antibody targeting of individual Notch receptors
Author / Creator:Wu, Yan ; Cain-Hom, Carol ; Choy, Lisa ; Hagenbeek, Thijs J. ; de Leon, Gladys P. ; Chen, Yongmei ; Finkle, David ; Venook, Rayna ; Wu, Xiumin ; Ridgway, John ; Schahin-Reed, Dorreyah ; Dow, Graham J. ; Shelton, Amy ; Stawicki, Scott ; Watts, Ryan J. ; Zhang, Jeff ; Choy, Robert ; Howard, Peter ; Kadyk, Lisa ; Yan, Minhong ; Zha, Jiping ; Callahan, Christopher A. ; Hymowitz, Sarah G. ; Siebel, Christian W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-04, Vol.464 (7291), p.1052-1057
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Angiogenesis Inhibitors: Current Strategies and Future Prospects
Author / Creator:Cook, Kristina M ; Figg, William D
Publisher:Atlanta: Wiley Subscription Services, Inc
Journal title:CA: a cancer journal for clinicians, 2010-07, Vol.60 (4), p.222
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Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Author / Creator:Montero-Melendez, Trinidad ; Nagano, Ai ; Chelala, Claude ; Filer, Andrew ; Buckley, Christopher D. ; Perretti, Mauro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.745-745, Article 745
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Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling
Author / Creator:Benedito, Rui ; Rocha, Susana F. ; Woeste, Marina ; Zamykal, Martin ; Radtke, Freddy ; Casanovas, Oriol ; Duarte, Antonio ; Pytowski, Bronislaw ; Adams, Ralf H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-04, Vol.484 (7392), p.110-114
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Showing 1 to 20 of 164 results

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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

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Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

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Therapeutic modulation of Notch signalling — are we there yet?

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Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

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Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

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COVID-19 in the heart and the lungs: could we “Notch” the inflammatory storm?

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Neurogenic radial glia in the outer subventricular zone of human neocortex

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Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH

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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

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Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

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Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway

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Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma

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Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

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A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma

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High mitogenic stimulation arrests angiogenesis

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Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

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Therapeutic antibody targeting of individual Notch receptors

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Angiogenesis Inhibitors: Current Strategies and Future Prospects

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Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

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Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

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