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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
Author / Creator:Fadista, João ; Vikman, Petter ; Laakso, Emilia Ottosson ; Mollet, Inês Guerra ; Esguerra, Jonathan Lou ; Taneera, Jalal ; Storm, Petter ; Osmark, Peter ; Ladenvall, Claes ; Prasad, Rashmi B. ; Hansson, Karin B. ; Finotello, Francesca ; Uvebrant, Kristina ; Ofori, Jones K. ; Di Camillo, Barbara ; Krus, Ulrika ; Cilio, Corrado M. ; Hansson, Ola ; Eliasson, Lena ; Rosengren, Anders H. ; Renström, Erik ; Wollheim, Claes B. ; Groop, Leif
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (38), p.13924-13929
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A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
Author / Creator:Ye, Yingying ; Barghouth, Mohammad ; Dou, Haiqiang ; Luan, Cheng ; Wang, Yongzhi ; Karagiannopoulos, Alexandros ; Jiang, Xiaoping ; Krus, Ulrika ; Fex, Malin ; Zhang, Quan ; Eliasson, Lena ; Rorsman, Patrik ; Zhang, Enming ; Renström, Erik
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.4237-16, Article 4237
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Elevated circulating follistatin associates with an increased risk of type 2 diabetes
Author / Creator:Wu, Chuanyan ; Borné, Yan ; Gao, Rui ; López Rodriguez, Maykel ; Roell, William C. ; Wilson, Jonathan M. ; Regmi, Ajit ; Luan, Cheng ; Aly, Dina Mansour ; Peter, Andreas ; Machann, Jürgen ; Staiger, Harald ; Fritsche, Andreas ; Birkenfeld, Andreas L. ; Tao, Rongya ; Wagner, Robert ; Canouil, Mickaël ; Hong, Mun-Gwan ; Schwenk, Jochen M. ; Ahlqvist, Emma ; Kaikkonen, Minna U. ; Nilsson, Peter ; Shore, Angela C. ; Khan, Faisel ; Natali, Andrea ; Melander, Olle ; Orho-Melander, Marju ; Nilsson, Jan ; Häring, Hans-Ulrich ; Renström, Erik ; Wollheim, Claes B. ; Engström, Gunnar ; Weng, Jianping ; Pearson, Ewan R. ; Franks, Paul W. ; White, Morris F. ; Duffin, Kevin L. ; Vaag, Allan Arthur ; Laakso, Markku ; Stefan, Norbert ; Groop, Leif ; De Marinis, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6486-10, Article 6486
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The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells
Author / Creator:Paul, Gesine ; Özen, Ilknur ; Christophersen, Nicolaj S. ; Reinbothe, Thomas ; Bengzon, Johan ; Visse, Edward ; Jansson, Katarina ; Dannaeus, Karin ; Henriques-Oliveira, Catarina ; Roybon, Laurent ; Anisimov, Sergey V. ; Renström, Erik ; Svensson, Mikael ; Haegerstrand, Anders ; Brundin, Patrik
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e35577
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Transcriptional analysis of islets of Langerhans from organ donors of different ages
Author / Creator:Seiron, Peter ; Stenwall, Anton ; Hedin, Anders ; Granlund, Louise ; Esguerra, Jonathan Lou S. ; Volkov, Petr ; Renström, Erik ; Korsgren, Olle ; Lundberg, Marcus ; Skog, Oskar
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-03, Vol.16 (3), p.e0247888
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A circular RNA generated from an intron of the insulin gene controls insulin secretion
Author / Creator:Stoll, Lisa ; Rodríguez-Trejo, Adriana ; Guay, Claudiane ; Brozzi, Flora ; Bayazit, Mustafa Bilal ; Gattesco, Sonia ; Menoud, Véronique ; Sobel, Jonathan ; Marques, Ana Claudia ; Venø, Morten Trillingsgaard ; Esguerra, Jonathan Lou S. ; Barghouth, Mohammad ; Suleiman, Mara ; Marselli, Lorella ; Kjems, Jørgen ; Eliasson, Lena ; Renström, Erik ; Bouzakri, Karim ; Pinget, Michel ; Marchetti, Piero ; Regazzi, Romano
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-11, Vol.11 (1), p.5611-13, Article 5611
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Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes
Author / Creator:Rosengren, Anders H ; Jokubka, Ramunas ; Tojjar, Damon ; Granhall, Charlotte ; Hansson, Ola ; Li, Dai-Qing ; Nagaraj, Vini ; Reinbothe, Thomas M ; Tuncel, Jonatan ; Eliasson, Lena ; Groop, Leif ; Rorsman, Patrik ; Salehi, Albert ; Lyssenko, Valeriya ; Luthman, Holger ; Renström, Erik
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-01, Vol.327 (5962), p.217-220
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Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
Author / Creator:Rosengren, Anders H. ; Braun, Matthias ; Mahdi, Taman ; Andersson, Sofia A. ; Travers, Mary E. ; Shigeto, Makoto ; Zhang, Enming ; Almgren, Peter ; Ladenvall, Claes ; Axelsson, Annika S. ; Edlund, Anna ; Pedersen, Morten Gram ; Jonsson, Anna ; Ramracheya, Reshma ; Tang, Yunzhao ; Walker, Jonathan N. ; Barrett, Amy ; Johnson, Paul R.V. ; Lyssenko, Valeriya ; McCarthy, Mark I. ; Groop, Leif ; Salehi, Albert ; Gloyn, Anna L. ; Renström, Erik ; Rorsman, Patrik ; Eliasson, Lena
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2012-07, Vol.61 (7), p.1726-1733
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CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
Author / Creator:Abels, Mia ; Riva, Matteo ; Bennet, Hedvig ; Ahlqvist, Emma ; Dyachok, Oleg ; Nagaraj, Vini ; Shcherbina, Liliya ; Fred, Rikard G. ; Poon, Wenny ; Sörhede-Winzell, Maria ; Fadista, Joao ; Lindqvist, Andreas ; Kask, Lena ; Sathanoori, Ramasri ; Dekker-Nitert, Marloes ; Kuhar, Michael J. ; Ahrén, Bo ; Wollheim, Claes B. ; Hansson, Ola ; Tengholm, Anders ; Fex, Malin ; Renström, Erik ; Groop, Leif ; Lyssenko, Valeriya ; Wierup, Nils
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2016-09, Vol.59 (9), p.1928-1937
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Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA
Author / Creator:Chen, Dongfeng ; Zuo, Duo ; Luan, Cheng ; Liu, Min ; Ran, Liang ; Sun, Yingyu ; Persson, Annette ; Englund, Elisabet ; Salford, Leif G. ; Renström, Erik ; Fan, Xiaolong ; Zhang, Enming
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e87281
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Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression
Author / Creator:Buda, Pawel ; Reinbothe, Thomas ; Nagaraj, Vini ; Mahdi, Taman ; Luan, Cheng ; Tang, Yunzhao ; Axelsson, Annika S. ; Li, Daiqing ; Rosengren, Anders H. ; Renström, Erik ; Zhang, Enming
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013, Vol.8 (5), p.e64462
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Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease
Author / Creator:Bompada, Pradeep ; Goncalves, Isabel ; Wu, Chuanyan ; Gao, Rui ; Sun, Jiangming ; Mir, Bilal Ahmad ; Luan, Cheng ; Renström, Erik ; Groop, Leif ; Weng, Jianping ; Hansson, Ola ; Edsfeldt, Andreas ; De Marinis, Yang
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2021-12, Vol.9 (12), p.1908
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Why Treatment Fails in Type 2 Diabetes
Author / Creator:Rosengren, Anders ; Jing, Xingjun ; Eliasson, Lena ; Renström, Erik
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2008-10, Vol.5 (10), p.e215
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Separately Inherited Defects in Insulin Exocytosis and β-Cell Glucose Metabolism Contribute to Type 2 Diabetes
Author / Creator:Granhall, Charlotte ; Rosengren, Anders H. ; Renström, Erik ; Luthman, Holger
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2006-12, Vol.55 (12), p.3494-3500
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The Voltage Sensitive Lc-type Ca2+Channel Is Functionally Coupled to the Exocytotic Machinery
Author / Creator:Wiser, Ofer ; Trus, Michael ; Hernandez, Ana ; Renstrom, Erik ; Barg, Sebastian ; Rorsman, Patrik ; Atlas, Daphne
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-01, Vol.96 (1), p.248-253
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Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes
Author / Creator:Hansson, Ola ; Zhou, Yuedan ; Renström, Erik ; Osmark, Peter
Journal title:Current diabetes reports, 2010-12, Vol.10 (6), p.444-451
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Reduced insulin exocytosis in human pancreatic [beta]-cells with gene variants linked to type 2 diabetes.(ORIGINAL ARTICLE)
Author / Creator:Rosengren, Anders H ; Braun, Matthias ; Mahdi, Taman ; Andersson, Sofia A ; Travers, Mary E ; Shigeto, Makoto ; Zhang, Enming ; Almgren, Peter ; Ladenvall, Claes ; Axelsson, Annika S ; Edlund, Anna ; Pedersen, Morten Gram ; Jonsson, Anna ; Ramracheya, Reshma ; Tang, Yunzhao ; Walker, Jonathan N ; Barrett, Amy ; Johnson, Paul R.V ; Lyssenko, Valeriya ; McCarthy, Mark I ; Groop, Leif ; Salehi, Albert ; Gloyn, Anna L ; Renstrom, Erik ; Rorsman, Patrik ; Eliasson, Lena
Publisher:New York: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2012-07, Vol.61 (7), p.1726
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CaV2.3 calcium channels control second-phase insulin release
Author / Creator:Jing, Xingjun ; Li, Dai-Qing ; Olofsson, Charlotta S. ; Salehi, Albert ; Surve, Vikas V. ; Caballero, José ; Ivarsson, Rosita ; Lundquist, Ingmar ; Pereverzev, Alexey ; Schneider, Toni ; Rorsman, Patrik ; Renström, Erik
Journal title:The Journal of clinical investigation, 2005-01, Vol.115 (1), p.146-154
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MAFA and MAFB regulate exocytosis‐related genes in human β‐cells
Author / Creator:Cataldo, Luis Rodrigo ; Singh, Tania ; Achanta, Kavya ; Bsharat, Sara ; Prasad, Rashmi B. ; Luan, Cheng ; Renström, Erik ; Eliasson, Lena ; Artner, Isabella
Publisher:England
Journal title:Acta Physiologica, 2022-02, Vol.234 (2), p.e13761-n/a
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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
Author / Creator:Golec, Ewelina ; Ekström, Alexander ; Noga, Maciej ; Omar-Hmeadi, Muhmmad ; Lund, Per-Eric ; Villoutreix, Bruno O. ; Krus, Ulrika ; Wozniak, Katarzyna ; Korsgren, Olle ; Renström, Erik ; Barg, Sebastian ; King, Ben C. ; Blom, Anna M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (24), p.1-10
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Showing 1 to 20 of 96 results

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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

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A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells

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Elevated circulating follistatin associates with an increased risk of type 2 diabetes

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The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells

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Transcriptional analysis of islets of Langerhans from organ donors of different ages

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A circular RNA generated from an intron of the insulin gene controls insulin secretion

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Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

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Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

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CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

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Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA

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Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression

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Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease

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Why Treatment Fails in Type 2 Diabetes

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Separately Inherited Defects in Insulin Exocytosis and β-Cell Glucose Metabolism Contribute to Type 2 Diabetes

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The Voltage Sensitive Lc-type Ca2+Channel Is Functionally Coupled to the Exocytotic Machinery

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Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes

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Reduced insulin exocytosis in human pancreatic [beta]-cells with gene variants linked to type 2 diabetes.(ORIGINAL ARTICLE)

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CaV2.3 calcium channels control second-phase insulin release

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MAFA and MAFB regulate exocytosis‐related genes in human β‐cells

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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

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