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Newsletter articlesFull Text
INTERNATIONAL PATENT: CENTESSA PHARMACEUTICALS (OREXIA) LIMITED, SAWYER, TOMI K. FILES APPLICATION FOR "PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2024
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Newsletter articlesFull Text
INTERNATIONAL PATENT: CENTESSA PHARMACEUTICALS (OREXIA) LIMITED, SAWYER, TOMI K., DE GRAAF, CHRIS FILES APPLICATION FOR "PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2024
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , CARRINGTON, PAUL, E. , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. F...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. FILES APPLICATION FOR "S...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. FILES APPLICATION FOR "S...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , MSD INTERNATIONAL GMBH (SINGAPORE BRANCH) , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , BOYER, NICOLAS, C. , GARRIGOU, MICHAEL, B. , HA, SOOKHEE NICOL...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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Newsletter articlesFull Text
INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , MSD INTERNATIONAL GMBH (SINGAPORE BRANCH) , ARONICA, PIETRO , BROWN, CHRISTOPER, J. , FERRER, FERNANDO, J....
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2020
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ArticlesPeer ReviewedFull Text
Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
Author / Creator:Chang, Yong S. ; Graves, Bradford ; Guerlavais, Vincent ; Tovar, Christian ; Packman, Kathryn ; To, Kwong-Him ; Olson, Karen A. ; Kesavan, Kamala ; Gangurde, Pranoti ; Mukherjee, Aditi ; Baker, Theresa ; Darlak, Krzysztof ; Elkin, Carl ; Filipovic, Zoran ; Qureshi, Farooq Z. ; Cai, Hongliang ; Berry, Pamela ; Feyfant, Eric ; Shi, Xiangguo E. ; Horstick, James ; Annis, D. Allen ; Manning, Anthony M. ; Fotouhi, Nader ; Nash, Huw ; Vassilev, Lyubomir T. ; Sawyer, Tomi K.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (36), p.E3445-E3454
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ArticlesPeer ReviewedFull Text
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Author / Creator:Chandramohan, Arun ; Josien, Hubert ; Yuen, Tsz Ying ; Duggal, Ruchia ; Spiegelberg, Diana ; Yan, Lin ; Juang, Yu-Chi Angela ; Ge, Lan ; Aronica, Pietro G. ; Kaan, Hung Yi Kristal ; Lim, Yee Hwee ; Peier, Andrea ; Sherborne, Brad ; Hochman, Jerome ; Lin, Songnian ; Biswas, Kaustav ; Nestor, Marika ; Verma, Chandra S. ; Lane, David P. ; Sawyer, Tomi K. ; Garbaccio, Robert ; Henry, Brian ; Kannan, Srinivasaraghavan ; Brown, Christopher J. ; Johannes, Charles W. ; Partridge, Anthony W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.489-19, Article 489
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ArticlesPeer ReviewedFull Text
Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Author / Creator:Chandramohan, Arun ; Josien, Hubert ; Yuen, Tsz Ying ; Duggal, Ruchia ; Spiegelberg, Diana ; Yan, Lin ; Juang, Yu-Chi Angela ; Ge, Lan ; Aronica, Pietro G. ; Kaan, Hung Yi Kristal ; Lim, Yee Hwee ; Peier, Andrea ; Sherborne, Brad ; Hochman, Jerome ; Lin, Songnian ; Biswas, Kaustav ; Nestor, Marika ; Verma, Chandra S. ; Lane, David P. ; Sawyer, Tomi K. ; Garbaccio, Robert ; Henry, Brian ; Kannan, Srinivasaraghavan ; Brown, Christopher J. ; Johannes, Charles W. ; Partridge, Anthony W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1617-1
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Newsletter articlesFull Text
Aileron Therapeutics Inc, Guerlavais Vincent, Elkin Carl, Nash Huw M, Sawyer Tomi K, Graves Bradford J and Feyfant Eric File WIPO Patent Application for Peptidomimetic Macrocycles
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2013
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ArticlesPeer ReviewedFull Text
Design, Structure–Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists
Author / Creator:Sawyer, Jonathon R. ; Audie, Joseph A. ; Swanson, Jon ; Diller, David ; Santiago, Solimar ; Gribkoff, Valentin K. ; Ackerman, Allison ; Hruby, Victor J. ; Gobbo, Gianpaolo ; Bellucci, Michael A. ; Glauser, William A. ; Pentelute, Brad L. ; Sawyer, Tomi K.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-01, Vol.30 (1), p.12
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ArticlesPeer ReviewedFull Text
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties
Author / Creator:Partridge, Anthony W. ; Kaan, Hung Yi Kristal ; Juang, Yu-Chi ; Sadruddin, Ahmad ; Lim, Shuhui ; Brown, Christopher J. ; Ng, Simon ; Thean, Dawn ; Ferrer, Fernando ; Johannes, Charles ; Yuen, Tsz Ying ; Kannan, Srinivasaraghavan ; Aronica, Pietro ; Tan, Yaw Sing ; Pradhan, Mohan R. ; Verma, Chandra S. ; Hochman, Jerome ; Chen, Shiying ; Wan, Hui ; Ha, Sookhee ; Sherborne, Brad ; Lane, David P. ; Sawyer, Tomi K.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-06, Vol.24 (12), p.2292
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ArticlesPeer ReviewedFull Text
The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models
Author / Creator:Malyshev, Anton V. ; Pavshintcev, Vsevolod V. ; Mitkin, Nikita A. ; Sukhanova, Iuliia A. ; Gedzun, Vasilina R. ; Zlobin, Alexander S. ; Doronin, Igor I. ; Babkin, Gennady A. ; Sawyer, Tomi K.
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in behavioral neuroscience, 2024-02, Vol.18, p.1333258-1333258
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ArticlesPeer ReviewedFull Text
Activity of Dual SRC-ABL Inhibitors Highlights the Role of BCR/ABL Kinase Dynamics in Drug Resistance
Author / Creator:Azam, Mohammad ; Nardi, Valentina ; Shakespeare, William C. ; Metcalf, Chester A. ; Bohacek, Regine S. ; Wang, Yihan ; Sundaramoorthi, Raji ; Sliz, Piotr ; Veach, Darren R. ; Bornmann, William G. ; Clarkson, Bayard ; Dalgarno, David C. ; Sawyer, Tomi K. ; Daley, George Q.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (24), p.9244-9249
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ArticlesPeer ReviewedFull Text
Subthreshold activation of the melanocortin system causes generalized sensitization to anorectic agents in mice
Author / Creator:Dahir, Naima S. ; Gui, Yijun ; Wu, Yanan ; Sweeney, Patrick R. ; Rouault, Alix A.J. ; Williams, Savannah Y. ; Gimenez, Luis E. ; Sawyer, Tomi K. ; Joy, Stephen T. ; Mapp, Anna K. ; Cone, Roger D.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-07, Vol.134 (14), p.1-11
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ArticlesPeer ReviewedFull Text
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides
Author / Creator:Desai, Tanvi J. ; Habulihaz, Bahanu ; Cannon, Joe R. ; Chandramohan, Arun ; Kaan, Hung Yi Kristal ; Sadruddin, Ahmad ; Yuen, Tsz Ying ; Johannes, Charles ; Thean, Dawn ; Brown, Chris J. ; Lane, David P. ; Partridge, Anthony W. ; Evers, Raymond ; Sawyer, Tomi K. ; Hochman, Jerome
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2021-05, Vol.38 (5), p.843-850
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ArticlesPeer ReviewedFull Text
Assessing the Utility of In Vitro Screening Tools for Predicting Bio-Performance of Oral Peptide Delivery
Author / Creator:Gadgil, Prajakta ; Alleyne, Candice ; Feng, Kung-I ; Hu, Mengwei ; Gindy, Marian ; Buevich, Alexei V. ; Fauty, Scott ; Salituro, Gino ; Wen, Jianzhong ; Li, Ying ; Nofsinger, Rebecca ; Sawyer, Tomi K. ; Buist, Nicole
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2019-10, Vol.36 (10), p.151-15, Article 151
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Newsletter articlesFull Text
AILERON Therapeutics Appoints Tomi K. Sawyer as Chief Scientific Officer
Publisher:New York: Business Wire
Journal title:Business Wire, 2007
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ArticlesPeer ReviewedFull Text
Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides
Author / Creator:Desai, Tanvi J. ; Habulihaz, Bahanu ; Cannon, Joseph R. ; Chandramohan, Arun ; Kaan, Hung Yi Kristal ; Sadruddin, Ahmad ; Yuen, Tsz Ying ; Johannes, Charles ; Thean, Dawn ; Brown, Chris J. ; Lane, David P. ; Partridge, Anthony W. ; Evers, Raymond ; Sawyer, Tomi K. ; Hochman, Jerome
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2021-04, Vol.38 (4), p.735-736
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INTERNATIONAL PATENT: CENTESSA PHARMACEUTICALS (OREXIA) LIMITED, SAWYER, TOMI K. FILES APPLICATION FOR "PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS"

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INTERNATIONAL PATENT: CENTESSA PHARMACEUTICALS (OREXIA) LIMITED, SAWYER, TOMI K., DE GRAAF, CHRIS FILES APPLICATION FOR "PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS"

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INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , CARRINGTON, PAUL, E. , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. F...

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INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. FILES APPLICATION FOR "S...

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INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , BIANCHI, ELISABETTA , DENG, QIAOLIN , LIN, SONGNIAN , ORVIETO, FEDERICA , PALANI, ANANDAN , PESSI, ANTONELLO , SAWYER, TOMI, K. FILES APPLICATION FOR "S...

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INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , MSD INTERNATIONAL GMBH (SINGAPORE BRANCH) , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , BOYER, NICOLAS, C. , GARRIGOU, MICHAEL, B. , HA, SOOKHEE NICOL...

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INTERNATIONAL PATENT: MERCK SHARP DOHME CORP. , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , MSD INTERNATIONAL GMBH (SINGAPORE BRANCH) , ARONICA, PIETRO , BROWN, CHRISTOPER, J. , FERRER, FERNANDO, J....

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Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

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Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists

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Aileron Therapeutics Inc, Guerlavais Vincent, Elkin Carl, Nash Huw M, Sawyer Tomi K, Graves Bradford J and Feyfant Eric File WIPO Patent Application for Peptidomimetic Macrocycles

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Design, Structure–Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists

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Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

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The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models

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Activity of Dual SRC-ABL Inhibitors Highlights the Role of BCR/ABL Kinase Dynamics in Drug Resistance

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Subthreshold activation of the melanocortin system causes generalized sensitization to anorectic agents in mice

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Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides

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Assessing the Utility of In Vitro Screening Tools for Predicting Bio-Performance of Oral Peptide Delivery

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AILERON Therapeutics Appoints Tomi K. Sawyer as Chief Scientific Officer

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Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides

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