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ArticlesPeer ReviewedFull Text
Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes
Author / Creator:De Paiva, Mayara Rodrigues Brandão ; Lage, Nayara Almeida ; Guerra, Maria Carolina Andrade ; Mol, Marcos Paulo Gomes ; Ribeiro, Marcela Coelho Silva ; Fulgêncio, Gustavo De Oliveira ; Gomes, Dawidson A. ; Da Costa César, Isabela ; Fialho, Sílvia Ligório ; Silva-Cunha, Armando
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Documenta ophthalmologica, 2019-02, Vol.138 (1), p.3-19
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Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms
Author / Creator:Barlow, Adam D. ; Nicholson, Michael L. ; Herbert, Terry P.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-08, Vol.62 (8), p.2674-2682
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AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes
Author / Creator:Guo, Yuanyuan ; Lin, Cai ; Xu, Peng ; Wu, Shan ; Fu, Xiujun ; Xia, Weidong ; Yao, Min
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-11, Vol.6 (1), p.36416-16, Article 36416
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Phase I/II study of temsirolimus for patients with unresectable Hepatocellular Carcinoma (HCC)- a correlative study to explore potential biomarkers for response
Author / Creator:Yeo, Winnie ; Chan, Stephen L ; Mo, Frankie KF ; Chu, Cheuk M ; Hui, Joyce WY ; Tong, Joanne HM ; Chan, Anthony WH ; Koh, Jane ; Hui, Edwin P ; Loong, Herbert ; Lee, Kirsty ; Li, Leung ; Ma, Brigette ; To, Ka F ; Yu, Simon CH
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2015-05, Vol.15 (1), p.395-395, Article 395
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Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis
Author / Creator:Minton, Dennis M. ; Elliehausen, Christian J. ; Javors, Martin A. ; Santangelo, Kelly S. ; Konopka, Adam R.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2021-10, Vol.23 (1), p.253-14, Article 253
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mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes
Author / Creator:Fraenkel, Merav ; Ketzinel-Gilad, Mali ; Ariav, Yafa ; Pappo, Orit ; Karaca, Melis ; Castel, Julien ; Berthault, Marie-France ; Magnan, Christophe ; Cerasi, Erol ; Kaiser, Nurit ; Leibowitz, Gil
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2008-04, Vol.57 (4), p.945-957
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Oligo(Lactic Acid)8-Rapamycin Prodrug-Loaded Poly(Ethylene Glycol)-block-Poly(Lactic Acid) Micelles for Injection
Author / Creator:Tam, Yu Tong ; Repp, Lauren ; Ma, Zhi-Xiong ; Feltenberger, John B. ; Kwon, Glen S.
Publisher:New York: Springer US
Journal title:Pharmaceutical research, 2019-05, Vol.36 (5), p.70-10, Article 70
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Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury
Author / Creator:Wang, Wei-Hung ; Chien, Ting-Han ; Fan, Sabrina Mai-Yi ; Huang, Wen-Yen ; Lai, Shih-Fan ; Wu, June-Tai ; Lin, Sung-Jan
Publisher:United States: The Radiation Research Society
Journal title:Radiation research, 2017-12, Vol.188 (6), p.761-769
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The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death
Author / Creator:Fan, Jia-Dong ; Lei, Pin-Ji ; Zheng, Jun-Yi ; Wang, Xiang ; Li, Shangze ; Liu, Huan ; He, Yi-Lei ; Wang, Zhao-Ning ; Wei, Gang ; Zhang, Xiaodong ; Li, Lian-Yun ; Wu, Min
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-01, Vol.10 (1), p.e0116782
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Galuteolin Inhibited Autophagy for Neuroprotection Against Transient Focal Cerebral Ischemia in Rats
Author / Creator:Zhu, Juxun ; Wang, Liyun ; Zhang, Jinping
Publisher:New York: Springer US
Journal title:Neuromolecular medicine, 2020-12, Vol.22 (4), p.493-502
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Combination of Rapamycin and Protein Tyrosine Kinase (PTK) Inhibitors for the Treatment of Leukemias Caused by Oncogenic PTKs
Author / Creator:Mohi, M. Golam ; Boulton, Christina ; Gu, Ting-Lei ; Sternberg, David W. ; Neuberg, Donna ; Griffin, James D. ; Gilliland, D. Gary ; Neel, Benjamin G. ; Ruderman, Joan V.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.3130-3135
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Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
Author / Creator:De Cillà, Stefano De ; Farruggio, Serena ; Vujosevic, Stela ; Raina, Giulia ; Filippini, Davide ; Gatti, Valentina ; Clemente, Nausicaa ; Mary, David ; Vezzola, Diego ; Casini, Giamberto ; Rossetti, Luca ; Grossini, Elena
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2017-01, Vol.42 (5), p.1725-1738
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Phase I study of oral ridaforolimus in combination with paclitaxel and carboplatin in patients with solid tumor cancers
Author / Creator:Chon, Hye Sook ; Kang, Sokbom ; Lee, Jae K. ; Apte, Sachin M. ; Shahzad, Mian M. ; Williams-Elson, Irene ; Wenham, Robert M.
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2017-06, Vol.17 (1), p.407-407, Article 407
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Electroacupuncture pretreatment induces tolerance against cerebral ischemia/reperfusion injury through inhibition of the autophagy pathway
Author / Creator:WU, ZHOUQUAN ; ZOU, ZHIQING ; ZOU, RONG ; ZHOU, XIANJU ; CUI, SUYANG
Publisher:Greece: D.A. Spandidos
Journal title:Molecular medicine reports, 2015-06, Vol.11 (6), p.4438-4446
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Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells
Author / Creator:Yang, Jianhong ; Zhou, Yongzhao ; Cheng, Xia ; Fan, Yi ; He, Shichao ; Li, Shucai ; Ye, Haoyu ; Xie, Caifeng ; Wu, Wenshuang ; Li, Chunyan ; Pei, Heying ; Li, Luyuan ; Wei, Zhe ; Peng, Aihua ; Wei, Yuquan ; Li, Weimin ; Chen, Lijuan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-01, Vol.5 (1), p.7697, Article 7697
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Autophagy Activation by Rapamycin Before Hypoxia-Reoxygenation Reduces Endoplasmic Reticulum Stress in Alveolar Epithelial Cells
Author / Creator:Fan, Tao ; Chen, Lei ; Huang, Zhixin ; Wang, Wei ; Zhang, Boyou ; Xu, Yao ; Mao, Zhangfan ; Hu, Hao ; Geng, Qing
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2017-01, Vol.41 (1), p.79-90
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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets
Author / Creator:Bell, Ewan ; Cao, Xiaopei ; Moibi, Jacob A. ; Greene, Scott R. ; Young, Robert ; Trucco, Matteo ; Gao, Zhiyong ; Matschinsky, Franz M. ; Deng, Shaoping ; Markman, James F. ; Naji, Ali ; Wolf, Bryan A.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2003-11, Vol.52 (11), p.2731-2739
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Antiangiogenic Effect of Docetaxel and Everolimus as Individual and Dual-Drug-Loaded Micellar Nanocarriers
Author / Creator:Mishra, Gyan P. ; Doddapaneni, Bhuvana Shyam ; Nguyen, Duc ; Alani, Adam W. G.
Publisher:Boston: Springer US
Journal title:Pharmaceutical research, 2014-03, Vol.31 (3), p.660-669
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Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat
Author / Creator:Bohra, Rahul ; Schöning, Wenzel ; Klawitter, Jelena ; Brunner, Nina ; Schmitz, Volker ; Shokati, Touraj ; Lawrence, Ryan ; Arbelaez, Maria Fernanda ; Schniedewind, Björn ; Christians, Uwe ; Klawitter, Jost
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e48063
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Inhibition of Protein Deubiquitination by PR-619 Activates the Autophagic Pathway in OLN-t40 Oligodendroglial Cells
Author / Creator:Seiberlich, Veronika ; Borchert, Janika ; Zhukareva, Victoria ; Richter-Landsberg, Christiane
Publisher:Boston: Springer US
Journal title:Cell biochemistry and biophysics, 2013-09, Vol.67 (1), p.149-160
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Showing 1 to 20 of 37 results

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Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes

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Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms

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AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

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Phase I/II study of temsirolimus for patients with unresectable Hepatocellular Carcinoma (HCC)- a correlative study to explore potential biomarkers for response

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Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis

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mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

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Oligo(Lactic Acid)8-Rapamycin Prodrug-Loaded Poly(Ethylene Glycol)-block-Poly(Lactic Acid) Micelles for Injection

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Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury

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The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death

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Galuteolin Inhibited Autophagy for Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

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Combination of Rapamycin and Protein Tyrosine Kinase (PTK) Inhibitors for the Treatment of Leukemias Caused by Oncogenic PTKs

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Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy

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Phase I study of oral ridaforolimus in combination with paclitaxel and carboplatin in patients with solid tumor cancers

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Electroacupuncture pretreatment induces tolerance against cerebral ischemia/reperfusion injury through inhibition of the autophagy pathway

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Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells

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Autophagy Activation by Rapamycin Before Hypoxia-Reoxygenation Reduces Endoplasmic Reticulum Stress in Alveolar Epithelial Cells

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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

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Antiangiogenic Effect of Docetaxel and Everolimus as Individual and Dual-Drug-Loaded Micellar Nanocarriers

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Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat

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Inhibition of Protein Deubiquitination by PR-619 Activates the Autophagic Pathway in OLN-t40 Oligodendroglial Cells

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