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LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway
Author / Creator:Wu, Nan ; Jiang, Mingzuo ; Liu, Haiming ; Chu, Yi ; Wang, Dan ; Cao, Jiayi ; Wang, Zhiyang ; Xie, Xin ; Han, Yuying ; Xu, Bing
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-01, Vol.28 (1), p.219-232
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Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein
Author / Creator:Yuan, Tao ; Chen, Zibo ; Yan, Fangjie ; Qian, Meijia ; Luo, Hong ; Ye, Song ; Cao, Ji ; Ying, Meidan ; Dai, Xiaoyang ; Gai, Renhua ; Yang, Bo ; He, Qiaojun ; Zhu, Hong
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2020-01, Vol.14 (1), p.197-210
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SnoN Stabilizes the SMAD3/SMAD4 Protein Complex
Author / Creator:Walldén, Karin ; Nyman, Tomas ; Hällberg, B. Martin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.46370-46370, Article 46370
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miR‐422a suppresses SMAD4 protein expression and promotes resistance to muscle loss
Author / Creator:Paul, Richard ; Lee, Jen ; Donaldson, Anna V. ; Connolly, Martin ; Sharif, Mohammad ; Natanek, Samantha Amanda ; Rosendahl, Ulrich ; Polkey, Michael I. ; Griffiths, Mark ; Kemp, Paul R.
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Journal of cachexia, sarcopenia and muscle, 2018-02, Vol.9 (1), p.119-128
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A reinforcing HNF4–SMAD4 feed-forward module stabilizes enterocyte identity
Author / Creator:Chen, Lei ; Toke, Natalie H. ; Luo, Shirley ; Vasoya, Roshan P. ; Fullem, Robert L. ; Parthasarathy, Aditya ; Perekatt, Ansu O. ; Verzi, Michael P.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2019-05, Vol.51 (5), p.777-785
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Loss of CA-IX and SMAD4 Staining Support the Diagnosis of Ductal Adenocarcinoma of Pancreas
Author / Creator:Al-Othman, Yazan ; Pruetz, Barbara L ; Qu, Zhenhong ; Zhang, Ping ; Nasir, Aqsa
Publisher:Northfield: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2024-09, Vol.148 (9), p.E173-E174
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Suppressive cancer nonstop extension mutations increase C-terminal hydrophobicity and disrupt evolutionarily conserved amino acid patterns
Author / Creator:Ghosh, Avantika ; Riester, Marisa ; Pal, Jagriti ; Lainde, Kadri-Ann ; Tangermann, Carla ; Wanninger, Angela ; Dueren, Ursula K. ; Dhamija, Sonam ; Diederichs, Sven
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-10, Vol.15 (1), p.9209-16, Article 9209
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Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways
Author / Creator:Guglielmi, Luca ; Heliot, Claire ; Kumar, Sunil ; Alexandrov, Yuriy ; Gori, Ilaria ; Papaleonidopoulou, Foteini ; Barrington, Christopher ; East, Philip ; Economou, Andrew D. ; French, Paul M. W. ; McGinty, James ; Hill, Caroline S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6374-6374, Article 6374
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O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation
Author / Creator:Kim, Yeon Jung ; Kang, Min Jueng ; Kim, Eunah ; Kweon, Tae Hyun ; Park, Yun Soo ; Ji, Suena ; Yang, Won Ho ; Yi, Eugene C. ; Cho, Jin Won
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-11, Vol.10 (1), p.19908-19908, Article 19908
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Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells
Author / Creator:Hirata, H ; Hinoda, Y ; Shahryari, V ; Deng, G ; Tanaka, Y ; Tabatabai, Z L ; Dahiya, R
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2014-03, Vol.110 (6), p.1645-1654
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Digital next-generation sequencing identifies low-abundance mutations in pancreatic juice samples collected from the duodenum of patients with pancreatic cancer and intraductal papillary mucinous neop...
Author / Creator:Yu, Jun ; Sadakari, Yoshihiko ; Shindo, Koji ; Suenaga, Masaya ; Brant, Aaron ; Almario, Jose Alejandro Navarro ; Borges, Michael ; Barkley, Thomas ; Fesharakizadeh, Shahriar ; Ford, Madeline ; Hruban, Ralph H ; Shin, Eun Ji ; Lennon, Anne Marie ; Canto, Marcia Irene ; Goggins, Michael
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-09, Vol.66 (9), p.1677-1687
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PRMT5 methylating SMAD4 activates TGF-β signaling and promotes colorectal cancer metastasis
Author / Creator:Liu, Anyi ; Yu, Chengxin ; Qiu, Cheng ; Wu, Qi ; Huang, Changsheng ; Li, Xun ; She, Xiaowei ; Wan, Kairui ; Liu, Lang ; Li, Mao ; Wang, Zhihong ; Chen, Yaqi ; Hu, Fuqing ; Song, Da ; Li, Kangdi ; Zhao, Chongchong ; Deng, Haiteng ; Sun, Xuling ; Xu, Feng ; Lai, Senyan ; Luo, Xuelai ; Hu, Junbo ; Wang, Guihua
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2023-05, Vol.42 (19), p.1572-1584
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Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells
Author / Creator:Thacker, Pooja Chandrakant ; Karunagaran, Devarajan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0120045
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Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer
Author / Creator:Hu, Muren ; Feng, Chang ; Yuan, Qianqin ; Liu, Chenbin ; Ge, Bujun ; Sun, Fenyong ; Zhu, Xiaoli
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1307-1307, Article 1307
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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
Author / Creator:Ding, Zhihu ; Wu, Chang-Jiun ; Chu, Gerald C. ; Xiao, Yonghong ; Ho, Dennis ; Zhang, Jingfang ; Perry, Samuel R. ; Labrot, Emma S. ; Wu, Xiaoqiu ; Lis, Rosina ; Hoshida, Yujin ; Hiller, David ; Hu, Baoli ; Jiang, Shan ; Zheng, Hongwu ; Stegh, Alexander H. ; Scott, Kenneth L. ; Signoretti, Sabina ; Bardeesy, Nabeel ; Wang, Y. Alan ; Hill, David E. ; Golub, Todd R. ; Stampfer, Meir J. ; Wong, Wing H. ; Loda, Massimo ; Mucci, Lorelei ; Chin, Lynda ; DePinho, Ronald A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-02, Vol.470 (7333), p.269-273
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Smad4 deficiency in hepatocytes attenuates NAFLD progression via inhibition of lipogenesis and macrophage polarization
Author / Creator:Yang, Wei ; Yan, Xuanxuan ; Chen, Rui ; Xin, Xin ; Ge, Shuang ; Zhao, Yongxiang ; Yan, Xinlong ; Zhang, Jinhua
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-01, Vol.16 (1), p.58-11, Article 58
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Large Cell Neuroendocrine Carcinoma Arising in Pancreatoblastoma With TP53 and SMAD4 Mutation: A Clinicopathologic Study of a Rare Entity
Author / Creator:Nwosu, Ifeomachukwu E ; Zhang, Jenny ; Elliott, Alexis ; Sun, Belinda
Publisher:Northfield: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2024-09, Vol.148 (9), p.E183-E184
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Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors
Author / Creator:Martin-Malpartida, Pau ; Batet, Marta ; Kaczmarska, Zuzanna ; Freier, Regina ; Gomes, Tiago ; Aragón, Eric ; Zou, Yilong ; Wang, Qiong ; Xi, Qiaoran ; Ruiz, Lidia ; Vea, Angela ; Márquez, José A. ; Massagué, Joan ; Macias, Maria J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.2070-15, Article 2070
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BMP-4 enhances epithelial mesenchymal transition and cancer stem cell properties of breast cancer cells via Notch signaling
Author / Creator:Choi, Sanghyuk ; Yu, Jinyeong ; Park, Aran ; Dubon, Maria Jose ; Do, Jungbeom ; Kim, Youngjae ; Nam, Donghyun ; Noh, Jinok ; Park, Ki-Sook
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-08, Vol.9 (1), p.11724-14, Article 11724
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Pancreatic cancer
Author / Creator:Kamisawa, Terumi, Dr ; Wood, Laura D, MD ; Itoi, Takao, MD ; Takaori, Kyoichi, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-07, Vol.388 (10039), p.73-85
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LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway

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Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein

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SnoN Stabilizes the SMAD3/SMAD4 Protein Complex

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miR‐422a suppresses SMAD4 protein expression and promotes resistance to muscle loss

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A reinforcing HNF4–SMAD4 feed-forward module stabilizes enterocyte identity

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Loss of CA-IX and SMAD4 Staining Support the Diagnosis of Ductal Adenocarcinoma of Pancreas

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Suppressive cancer nonstop extension mutations increase C-terminal hydrophobicity and disrupt evolutionarily conserved amino acid patterns

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Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways

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O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation

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Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells

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Digital next-generation sequencing identifies low-abundance mutations in pancreatic juice samples collected from the duodenum of patients with pancreatic cancer and intraductal papillary mucinous neop...

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PRMT5 methylating SMAD4 activates TGF-β signaling and promotes colorectal cancer metastasis

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Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells

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Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer

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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

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Smad4 deficiency in hepatocytes attenuates NAFLD progression via inhibition of lipogenesis and macrophage polarization

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Large Cell Neuroendocrine Carcinoma Arising in Pancreatoblastoma With TP53 and SMAD4 Mutation: A Clinicopathologic Study of a Rare Entity

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Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors

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BMP-4 enhances epithelial mesenchymal transition and cancer stem cell properties of breast cancer cells via Notch signaling

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Pancreatic cancer

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