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487 results for Spliceosomes+-+metabolism

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ArticlesPeer ReviewedFull Text
Structural insights into intron catalysis and dynamics during splicing
Author / Creator:Xu, Ling ; Liu, Tianshuo ; Chung, Kevin ; Pyle, Anna Marie
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-12, Vol.624 (7992), p.682-688
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Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
Author / Creator:Nakane, Takanori ; Kimanius, Dari ; Lindahl, Erik ; Scheres, Sjors HW
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2018-06, Vol.7
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Complexity of the Alternative Splicing Landscape in Plants
Author / Creator:Reddy, Anireddy S.N. ; Marquez, Yamile ; Kalyna, Maria ; Barta, Andrea
Publisher:England: American Society of Plant Biologists
Journal title:The Plant cell, 2013-10, Vol.25 (10), p.3657-3683
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Splicing and transcription touch base: co-transcriptional spliceosome assembly and function
Author / Creator:Herzel, Lydia ; Ottoz, Diana S. M. ; Alpert, Tara ; Neugebauer, Karla M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2017-10, Vol.18 (10), p.637-650
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ArticlesPeer ReviewedFull Text
Mechanistic insights into precursor messenger RNA splicing by the spliceosome
Author / Creator:Shi, Yigong
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2017-11, Vol.18 (11), p.655-670
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Alternative splicing: a pivotal step between eukaryotic transcription and translation
Author / Creator:Kornblihtt, Alberto R. ; Schor, Ignacio E. ; Alló, Mariano ; Dujardin, Gwendal ; Petrillo, Ezequiel ; Muñoz, Manuel J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2013-03, Vol.14 (3), p.153-165
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Alternative Splicing at the Intersection of Biological Timing, Development, and Stress Responses
Author / Creator:Staiger, Dorothee ; Brown, John W.S.
Publisher:United States: American Society of Plant Biologists
Journal title:The Plant cell, 2013-10, Vol.25 (10), p.3640-3656
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Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins
Author / Creator:Van Nostrand, Eric L. ; Pratt, Gabriel A. ; Yee, Brian A. ; Wheeler, Emily C. ; Blue, Steven M. ; Mueller, Jasmine ; Park, Samuel S. ; Garcia, Keri E. ; Gelboin-Burkhart, Chelsea ; Nguyen, Thai B. ; Rabano, Ines ; Stanton, Rebecca ; Sundararaman, Balaji ; Wang, Ruth ; Fu, Xiang-Dong ; Graveley, Brenton R. ; Yeo, Gene W.
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2020-04, Vol.21 (1), p.90-90, Article 90
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Molecular roles and function of circular RNAs in eukaryotic cells
Author / Creator:Holdt, Lesca M. ; Kohlmaier, Alexander ; Teupser, Daniel
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2018-03, Vol.75 (6), p.1071-1098
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A unified mechanism for intron and exon definition and back-splicing
Author / Creator:Li, Xueni ; Liu, Shiheng ; Zhang, Lingdi ; Issaian, Aaron ; Hill, Ryan C. ; Espinosa, Sara ; Shi, Shasha ; Cui, Yanxiang ; Kappel, Kalli ; Das, Rhiju ; Hansen, Kirk C. ; Zhou, Z. Hong ; Zhao, Rui
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-09, Vol.573 (7774), p.375-380
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ArticlesPeer ReviewedFull Text
Spliceosomal disruption of the non-canonical BAF complex in cancer
Author / Creator:Inoue, Daichi ; Chew, Guo-Liang ; Liu, Bo ; Michel, Brittany C. ; Pangallo, Joseph ; D’Avino, Andrew R. ; Hitchman, Tyler ; North, Khrystyna ; Lee, Stanley Chun-Wei ; Bitner, Lillian ; Block, Ariele ; Moore, Amanda R. ; Yoshimi, Akihide ; Escobar-Hoyos, Luisa ; Cho, Hana ; Penson, Alex ; Lu, Sydney X. ; Taylor, Justin ; Chen, Yu ; Kadoch, Cigall ; Abdel-Wahab, Omar ; Bradley, Robert K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-10, Vol.574 (7778), p.432-436
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ArticlesPeer ReviewedFull Text
Genome organization around nuclear speckles drives mRNA splicing efficiency
Author / Creator:Bhat, Prashant ; Chow, Amy ; Emert, Benjamin ; Ettlin, Olivia ; Quinodoz, Sofia A. ; Strehle, Mackenzie ; Takei, Yodai ; Burr, Alex ; Goronzy, Isabel N. ; Chen, Allen W. ; Huang, Wesley ; Ferrer, Jose Lorenzo M. ; Soehalim, Elizabeth ; Goh, Say-Tar ; Chari, Tara ; Sullivan, Delaney K. ; Blanco, Mario R. ; Guttman, Mitchell
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-05, Vol.629 (8014), p.1165-1173
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ArticlesPeer ReviewedFull Text
Mechanism of 5′ splice site transfer for human spliceosome activation
Author / Creator:Charenton, Clément ; Wilkinson, Max E. ; Nagai, Kiyoshi
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6438), p.362-367
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Excised linear introns regulate growth in yeast
Author / Creator:Morgan, Jeffrey T. ; Fink, Gerald R. ; Bartel, David P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-01, Vol.565 (7741), p.606-611
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Pathogenic variants that alter protein code often disrupt splicing
Author / Creator:Soemedi, Rachel ; Cygan, Kamil J ; Rhine, Christy L ; Wang, Jing ; Bulacan, Charlston ; Yang, John ; Bayrak-Toydemir, Pinar ; McDonald, Jamie ; Fairbrother, William G
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-06, Vol.49 (6), p.848-855
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ArticlesPeer ReviewedFull Text
Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine
Author / Creator:Fica, Sebastian M ; Nagai, Kiyoshi
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2017-10, Vol.24 (10), p.791-799
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ArticlesPeer ReviewedFull Text
Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
Author / Creator:Ubaida-Mohien, Ceereena ; Lyashkov, Alexey ; Gonzalez-Freire, Marta ; Tharakan, Ravi ; Shardell, Michelle ; Moaddel, Ruin ; Semba, Richard D ; Chia, Chee W ; Gorospe, Myriam ; Sen, Ranjan ; Ferrucci, Luigi
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-10, Vol.8
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Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers
Author / Creator:Sivaramakrishnan, Manaswini ; McCarthy, Kathleen D. ; Campagne, Sébastien ; Huber, Sylwia ; Meier, Sonja ; Augustin, Angélique ; Heckel, Tobias ; Meistermann, Hélène ; Hug, Melanie N. ; Birrer, Pascale ; Moursy, Ahmed ; Khawaja, Sarah ; Schmucki, Roland ; Berntenis, Nikos ; Giroud, Nicolas ; Golling, Sabrina ; Tzouros, Manuel ; Banfai, Balazs ; Duran-Pacheco, Gonzalo ; Lamerz, Jens ; Hsiu Liu, Ying ; Luebbers, Thomas ; Ratni, Hasane ; Ebeling, Martin ; Cléry, Antoine ; Paushkin, Sergey ; Krainer, Adrian R. ; Allain, Frédéric H.-T. ; Metzger, Friedrich
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1476-13, Article 1476
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The spliceosome is a therapeutic vulnerability in MYC-driven cancer
Author / Creator:Hsu, Tiffany Y.-T. ; Simon, Lukas M. ; Neill, Nicholas J. ; Marcotte, Richard ; Sayad, Azin ; Bland, Christopher S. ; Echeverria, Gloria V. ; Sun, Tingting ; Kurley, Sarah J. ; Tyagi, Siddhartha ; Karlin, Kristen L. ; Dominguez-Vidaña, Rocio ; Hartman, Jessica D. ; Renwick, Alexander ; Scorsone, Kathleen ; Bernardi, Ronald J. ; Skinner, Samuel O. ; Jain, Antrix ; Orellana, Mayra ; Lagisetti, Chandraiah ; Golding, Ido ; Jung, Sung Y. ; Neilson, Joel R. ; Zhang, Xiang H.-F. ; Cooper, Thomas A. ; Webb, Thomas R. ; Neel, Benjamin G. ; Shaw, Chad A. ; Westbrook, Thomas F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-09, Vol.525 (7569), p.384-388
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ArticlesPeer ReviewedFull Text
Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Author / Creator:Bertram, Karl ; Agafonov, Dmitry E. ; Liu, Wen-Ti ; Dybkov, Olexandr ; Will, Cindy L. ; Hartmuth, Klaus ; Urlaub, Henning ; Kastner, Berthold ; Stark, Holger ; Lührmann, Reinhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-02, Vol.542 (7641), p.318-323
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Structural insights into intron catalysis and dynamics during splicing

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Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

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Complexity of the Alternative Splicing Landscape in Plants

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Splicing and transcription touch base: co-transcriptional spliceosome assembly and function

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Mechanistic insights into precursor messenger RNA splicing by the spliceosome

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Alternative splicing: a pivotal step between eukaryotic transcription and translation

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Alternative Splicing at the Intersection of Biological Timing, Development, and Stress Responses

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Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins

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Molecular roles and function of circular RNAs in eukaryotic cells

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A unified mechanism for intron and exon definition and back-splicing

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Spliceosomal disruption of the non-canonical BAF complex in cancer

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Genome organization around nuclear speckles drives mRNA splicing efficiency

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Mechanism of 5′ splice site transfer for human spliceosome activation

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Excised linear introns regulate growth in yeast

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Pathogenic variants that alter protein code often disrupt splicing

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Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine

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Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria

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Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

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The spliceosome is a therapeutic vulnerability in MYC-driven cancer

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Cryo-EM structure of a human spliceosome activated for step 2 of splicing

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