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β-Hydroxybutyrate suppresses M1 macrophage polarization through β-hydroxybutyrylation of the STAT1 protein
Author / Creator:Bai, Ya-Ping ; Xing, Yu-Jie ; Ma, Tao ; Li, Kai ; Zhang, Teng ; Wang, De-Guo ; Wan, Shu-Jun ; Zhang, Cui-Wei ; Sun, Yue ; Wang, Meng-Yan ; Wang, Guo-Dong ; Pei, Wen-Jun ; Lv, Kun ; Zhang, Yan ; Kong, Xiang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2024-12, Vol.15 (12), p.874-14, Article 874
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Increased Levels of STAT1 Protein in Blood CD4 T Cells from Systemic Lupus Erythematosus Patients Are Associated with Perturbed Homeostasis of Activated CD45RA-FOXP3hi Regulatory Subset and Follow-Up...
Author / Creator:Goropevsek, Ales ; Gorenjak, Maksimiljan ; Gradisnik, Suzana ; Dai, Klara ; Holc, Iztok ; Hojs, Radovan ; Krajnc, Ivan ; Pahor, Artur ; Avcin, Tadej
Publisher:New Rochelle: Mary Ann Liebert, Inc
Journal title:Journal of interferon & cytokine research, 2017-06, Vol.37 (6), p.254-268
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Increased Levels of STAT1 Protein in Blood CD4 T Cells from Systemic Lupus Erythematosus Patients Are Associated with Perturbed Homeostasis of Activated CD45RA - FOXP3 hi Regulatory Subset and Follow-...
Author / Creator:Goropevšek, Aleš ; Gorenjak, Maksimiljan ; Gradišnik, Suzana ; Dai, Klara ; Holc, Iztok ; Hojs, Radovan ; Krajnc, Ivan ; Pahor, Artur ; Avčin, Tadej
Publisher:United States
Journal title:Journal of interferon & cytokine research, 2017-06, Vol.37 (6), p.254-268
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Expression of Concern: SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022, Vol.17 (3), p.e0266497-e0266497
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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Author / Creator:Miorin, Lisa ; Kehrer, Thomas ; Sanchez-Aparicio, Maria Teresa ; Zhang, Ke ; Cohen, Phillip ; Patel, Roosheel S. ; Cupic, Anastasija ; Makio, Tadashi ; Mei, Menghan ; Moreno, Elena ; Danziger, Oded ; White, Kris M. ; Rathnasinghe, Raveen ; Uccellini, Melissa ; Gao, Shengyan ; Aydillo, Teresa ; Mena, Ignacio ; Yin, Xin ; Martin-Sancho, Laura ; Krogan, Nevan J. ; Chanda, Sumit K. ; Schotsaert, Michael ; Wozniak, Richard W. ; Ren, Yi ; Rosenberg, Brad R. ; Fontoura, Beatriz M. A. ; García-Sastre, Adolfo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28344-28354
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IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy
Author / Creator:Ivashkiv, Lionel B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2018-09, Vol.18 (9), p.545-558
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JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression
Author / Creator:Owen, Katie L ; Brockwell, Natasha K ; Parker, Belinda S
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-12, Vol.11 (12), p.2002
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Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
Author / Creator:Wu, Haijian ; Zheng, Jingwei ; Xu, Shenbin ; Fang, Yuanjian ; Wu, Yingxi ; Zeng, Jianxiong ; Shao, Anwen ; Shi, Ligen ; Lu, Jianan ; Mei, Shuhao ; Wang, Xiaoyu ; Guo, Xinying ; Wang, Yirong ; Zhao, Zhen ; Zhang, Jianmin
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2021-01, Vol.18 (1), p.2-2, Article 2
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STAT proteins in cancer: orchestration of metabolism
Author / Creator:Li, Yi-Jia ; Zhang, Chunyan ; Martincuks, Antons ; Herrmann, Andreas ; Yu, Hua
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2023-03, Vol.23 (3), p.115-134
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Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance
Author / Creator:Tigano, Marco ; Vargas, Danielle C. ; Tremblay-Belzile, Samuel ; Fu, Yi ; Sfeir, Agnel
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-03, Vol.591 (7850), p.477-481
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An aberrant STAT pathway is central to COVID-19
Author / Creator:Matsuyama, Toshifumi ; Kubli, Shawn P. ; Yoshinaga, Steven K. ; Pfeffer, Klaus ; Mak, Tak W.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-12, Vol.27 (12), p.3209-3225
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DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells
Author / Creator:Sato, Hiro ; Niimi, Atsuko ; Yasuhara, Takaaki ; Permata, Tiara Bunga Mayang ; Hagiwara, Yoshihiko ; Isono, Mayu ; Nuryadi, Endang ; Sekine, Ryota ; Oike, Takahiro ; Kakoti, Sangeeta ; Yoshimoto, Yuya ; Held, Kathryn D. ; Suzuki, Yoshiyuki ; Kono, Koji ; Miyagawa, Kiyoshi ; Nakano, Takashi ; Shibata, Atsushi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1751-11, Article 1751
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NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death
Author / Creator:Huang, Di ; Chen, Jianing ; Yang, Linbin ; Ouyang, Qian ; Li, Jiaqian ; Lao, Liyan ; Zhao, Jinghua ; Liu, Jiang ; Lu, Yiwen ; Xing, Yue ; Chen, Fei ; Su, Fengxi ; Yao, Herui ; Liu, Qiang ; Su, Shicheng ; Song, Erwei
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-10, Vol.19 (10), p.1112-1125
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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model
Author / Creator:Kumar, Sumit ; Schoonderwoerd, Mark J A ; Kroonen, Jessie S ; de Graaf, Ilona J ; Sluijter, Marjolein ; Ruano, Dina ; González-Prieto, Román ; Verlaan-de Vries, Matty ; Rip, Jasper ; Arens, Ramon ; de Miranda, Noel F C C ; Hawinkels, Lukas J A C ; van Hall, Thorbald ; Vertegaal, Alfred C O
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2022-11, Vol.71 (11), p.2266-2283
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YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells
Author / Creator:Ma, Shoubao ; Sun, Baofa ; Duan, Songqi ; Han, Jingjing ; Barr, Tasha ; Zhang, Jianying ; Bissonnette, Marc B. ; Kortylewski, Marcin ; He, Chuan ; Chen, Jianjun ; Caligiuri, Michael A. ; Yu, Jianhua
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-02, Vol.24 (2), p.255-266
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Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy
Author / Creator:Xu, Yan-Ping ; Lv, Lei ; Liu, Ying ; Smith, Matthew D ; Li, Wen-Cai ; Tan, Xian-Ming ; Cheng, Meng ; Li, Zhijun ; Bovino, Michael ; Aubé, Jeffrey ; Xiong, Yue
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-10, Vol.130 (10), p.4316-4331
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Human STAT1 Gain-of-Function Heterozygous Mutations: Chronic Mucocutaneous Candidiasis and Type I Interferonopathy
Author / Creator:Okada, Satoshi ; Asano, Takaki ; Moriya, Kunihiko ; Boisson-Dupuis, Stephanie ; Kobayashi, Masao ; Casanova, Jean-Laurent ; Puel, Anne
Publisher:New York: Springer US
Journal title:Journal of clinical immunology, 2020-11, Vol.40 (8), p.1065-1081
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Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
Author / Creator:Ma, Jingwei ; Wei, Keke ; Liu, Junwei ; Tang, Ke ; Zhang, Huafeng ; Zhu, Liyan ; Chen, Jie ; Li, Fei ; Xu, Pingwei ; Chen, Jie ; Liu, Jincheng ; Fang, Haiqing ; Tang, Liang ; Wang, Dianheng ; Zeng, Liping ; Sun, Weiwei ; Xie, Jing ; Liu, Yuying ; Huang, Bo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-04, Vol.11 (1), p.1769-1769, Article 1769
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Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
Author / Creator:Sarkar, Mrinal K ; Hile, Grace A ; Tsoi, Lam C ; Xing, Xianying ; Liu, Jianhua ; Liang, Yun ; Berthier, Celine C ; Swindell, William R ; Patrick, Matthew T ; Shao, Shuai ; Tsou, Pei-Suen ; Uppala, Ranjitha ; Beamer, Maria A ; Srivastava, Anshika ; Bielas, Stephanie L ; Harms, Paul W ; Getsios, Spiro ; Elder, James T ; Voorhees, John J ; Gudjonsson, Johann E ; Kahlenberg, J Michelle
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2018-11, Vol.77 (11), p.1653-1664
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Activated STING in a Vascular and Pulmonary Syndrome
Author / Creator:Liu, Yin ; Jesus, Adriana A ; Marrero, Bernadette ; Yang, Dan ; Ramsey, Suzanne E ; Montealegre Sanchez, Gina A ; Tenbrock, Klaus ; Wittkowski, Helmut ; Jones, Olcay Y ; Kuehn, Hye Sun ; Lee, Chyi-Chia R ; DiMattia, Michael A ; Cowen, Edward W ; Gonzalez, Benito ; Palmer, Ira ; DiGiovanna, John J ; Biancotto, Angelique ; Kim, Hanna ; Tsai, Wanxia L ; Trier, Anna M ; Huang, Yan ; Stone, Deborah L ; Hill, Suvimol ; Kim, H. Jeffery ; St. Hilaire, Cynthia ; Gurprasad, Shakuntala ; Plass, Nicole ; Chapelle, Dawn ; Horkayne-Szakaly, Iren ; Foell, Dirk ; Barysenka, Andrei ; Candotti, Fabio ; Holland, Steven M ; Hughes, Jason D ; Mehmet, Huseyin ; Issekutz, Andrew C ; Raffeld, Mark ; McElwee, Joshua ; Fontana, Joseph R ; Minniti, Caterina P ; Moir, Susan ; Kastner, Daniel L ; Gadina, Massimo ; Steven, Alasdair C ; Wingfield, Paul T ; Brooks, Stephen R ; Rosenzweig, Sergio D ; Fleisher, Thomas A ; Deng, Zuoming ; Boehm, Manfred ; Paller, Amy S ; Goldbach-Mansky, Raphaela
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-08, Vol.371 (6), p.507-518
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β-Hydroxybutyrate suppresses M1 macrophage polarization through β-hydroxybutyrylation of the STAT1 protein

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Increased Levels of STAT1 Protein in Blood CD4 T Cells from Systemic Lupus Erythematosus Patients Are Associated with Perturbed Homeostasis of Activated CD45RA-FOXP3hi Regulatory Subset and Follow-Up...

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Increased Levels of STAT1 Protein in Blood CD4 T Cells from Systemic Lupus Erythematosus Patients Are Associated with Perturbed Homeostasis of Activated CD45RA - FOXP3 hi Regulatory Subset and Follow-...

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Expression of Concern: SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells

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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

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IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy

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JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression

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Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury

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STAT proteins in cancer: orchestration of metabolism

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Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance

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An aberrant STAT pathway is central to COVID-19

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DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

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NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death

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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model

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YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells

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Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy

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Human STAT1 Gain-of-Function Heterozygous Mutations: Chronic Mucocutaneous Candidiasis and Type I Interferonopathy

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Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

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Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa

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Activated STING in a Vascular and Pulmonary Syndrome

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