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ArticlesPeer ReviewedFull Text
Hypoxia in Diabetic Kidneys
Author / Creator:Takiyama, Yumi ; Haneda, Masakazu
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:BioMed research international, 2014-01, Vol.2014 (2014), p.1-10
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ArticlesPeer ReviewedFull Text
Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
Author / Creator:Watanabe, Jun ; Takiyama, Yumi ; Honjyo, Jun ; Makino, Yuichi ; Fujita, Yukihiro ; Tateno, Masatoshi ; Haneda, Masakazu
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150897-e0150897
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A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation
Author / Creator:Promsuwan, Suratsawadee ; Sawamoto, Kazuki ; Xu, Liang ; Nagashimada, Mayumi ; Nagata, Naoto ; Takiyama, Yumi
Publisher:Singapore: Springer Nature Singapore
Journal title:Diabetology international, 2024-01, Vol.15 (1), p.86-98
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A maternal high-fat diet induces fetal origins of NASH-HCC in mice
Author / Creator:Takiyama, Takao ; Sera, Toshihiro ; Nakamura, Masanori ; Hoshino, Masato ; Uesugi, Kentaro ; Horike, Shin-ichi ; Meguro-Horike, Makiko ; Bessho, Ryoichi ; Takiyama, Yuri ; Kitsunai, Hiroya ; Takeda, Yasutaka ; Sawamoto, Kazuki ; Yagi, Naoto ; Nishikawa, Yuji ; Takiyama, Yumi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-07, Vol.12 (1), p.13136-13136, Article 13136
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The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study
Author / Creator:Kitsunai, Hiroya ; Shinozaki, Yuka ; Furusawa, Sho ; Kitao, Naoyuki ; Ito, Miki ; Kurihara, Hiroyoshi ; Oba-Yamamoto, Chiho ; Takeuchi, Jun ; Nakamura, Akinobu ; Takiyama, Yumi ; Nomoto, Hiroshi
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2025-01, Vol.18 (1), p.129
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Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice
Author / Creator:Atageldiyeva, Kuralay ; Fujita, Yukihiro ; Yanagimachi, Tsuyoshi ; Mizumoto, Katsutoshi ; Takeda, Yasutaka ; Honjo, Jun ; Takiyama, Yumi ; Abiko, Atsuko ; Makino, Yuichi ; Haneda, Masakazu
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0157672-e0157672
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Pancreatic glucose-dependent insulinotropic polypeptide (GIP) (1–30) expression is upregulated in diabetes and PEGylated GIP(1–30) can suppress the progression of low-dose-STZ-induced hyperglycaemia i...
Author / Creator:Yanagimachi, Tsuyoshi ; Fujita, Yukihiro ; Takeda, Yasutaka ; Honjo, Jun ; Atageldiyeva, Kuralay K. ; Takiyama, Yumi ; Abiko, Atsuko ; Makino, Yuichi ; Kieffer, Timothy J. ; Haneda, Masakazu
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2016-03, Vol.59 (3), p.533-541
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Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test
Author / Creator:Takeda, Yasutaka ; Fujita, Yukihiro ; Bessho, Ryoichi ; Sato, Mao ; Abe, Tomoe ; Yanagimachi, Tsuyoshi ; Sakagami, Hidemitsu ; Abiko, Atsuko ; Takiyama, Yumi ; Ota, Tsuguhito ; Haneda, Masakazu
Publisher:England: BioMed Central Ltd
Journal title:BMC endocrine disorders, 2019-10, Vol.19 (1), p.99-99, Article 99
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ArticlesPeer ReviewedFull Text
A case of insulinoma diagnosed postpartum with hypoglycemic symptoms that were masked during pregnancy
Author / Creator:Abe, Tomoe ; Takeda, Yasutaka ; Takiyama, Takao ; Sasaki, Ayaka ; Bessho, Ryoichi ; Sato, Mao ; Kitsunai, Hiroya ; Sakagami, Hidemitsu ; Abiko, Atsuko ; Imai, Koji ; Yuzawa, Sayaka ; Tanino, Mishie ; Takiyama, Yumi
Publisher:England: John Wiley & Sons, Inc
Journal title:Clinical case reports, 2021-04, Vol.9 (4), p.1991-1998
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ArticlesPeer ReviewedFull Text
Alternative form of glucose‐dependent insulinotropic polypepide and its physiology
Author / Creator:Fujita, Yukihiro ; Yanagimachi, Tsuyoshi ; Takeda, Yasutaka ; Honjo, Jun ; Takiyama, Yumi ; Abiko, Atsuko ; Makino, Yuichi ; Haneda, Masakazu
Publisher:Japan: John Wiley & Sons, Inc
Journal title:Journal of diabetes investigation, 2016-04, Vol.7 (S1), p.33-37
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ArticlesPeer ReviewedFull Text
High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells
Author / Creator:Kitsunai, Hiroya ; Makino, Yuichi ; Sakagami, Hidemitsu ; Mizumoto, Katsutoshi ; Yanagimachi, Tsuyoshi ; Atageldiyeva, Kuralay ; Takeda, Yasutaka ; Fujita, Yukihiro ; Abiko, Atsuko ; Takiyama, Yumi ; Haneda, Masakazu
Publisher:United States: John Wiley & Sons, Inc
Journal title:Physiological reports, 2016-03, Vol.4 (6), p.e12730-n/a
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ArticlesPeer ReviewedFull Text
Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy
Author / Creator:Bessho, Ryoichi ; Takiyama, Yumi ; Takiyama, Takao ; Kitsunai, Hiroya ; Takeda, Yasutaka ; Sakagami, Hidemitsu ; Ota, Tsuguhito
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.14754-12, Article 14754
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ArticlesPeer ReviewedFull Text
High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein
Author / Creator:Isoe, Tsubasa ; Makino, Yuichi ; Mizumoto, Katsutoshi ; Sakagami, Hidemitsu ; Fujita, Yukihiro ; Honjo, Jun ; Takiyama, Yumi ; Itoh, Hiroshi ; Haneda, Masakazu
Publisher:Basingstoke: Elsevier Inc
Journal title:Kidney international, 2010-07, Vol.78 (1), p.48-59
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ArticlesPeer ReviewedFull Text
Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin: A Possible Role of HIF-1α. Expression and Oxygen Metabolism
Author / Creator:TAKIYAMA, Yumi ; HARUMI, Tatsuo ; WATANABE, Jun ; FUJITA, Yukihiro ; HONJO, Jun ; SHIMIZU, Norihiko ; MAKINO, Yuichi ; HANEDA, Masakazu
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-03, Vol.60 (3), p.981-992
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ArticlesPeer ReviewedFull Text
Role of IGFBP7 in Diabetic Nephropathy: TGF-[beta]1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
Author / Creator:Watanabe, Jun ; Takiyama, Yumi ; Honjyo, Jun ; Makino, Yuichi ; Fujita, Yukihiro ; Tateno, Masatoshi ; Haneda, Masakazu
Publisher:Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150897
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ArticlesPeer ReviewedFull Text
Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin
Author / Creator:Takiyama, Yumi ; Harumi, Tatsuo ; Watanabe, Jun ; Fujita, Yukihiro ; Honjo, Jun ; Shimizu, Norihiko ; Makino, Yuichi ; Haneda, Masakazu
Journal title:Diabetes (New York, N.Y.), 2011-03, Vol.60 (3), p.981-992
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ArticlesPeer ReviewedFull Text
Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin: A Possible Role of HIF-1[alpha] Expression and Oxygen Metabolism
Author / Creator:Takiyama, Yumi ; Harumi, Tatsuo ; Watanabe, Jun ; Fujita, Yukihiro ; Honjo, Jun ; Shimizu, Norihiko ; Makino, Yuichi ; Haneda, Masakazu
Publisher:New York: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-03, Vol.60 (3), p.981
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ArticlesPeer ReviewedFull Text
Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms
Author / Creator:Matsuzawa, Kazuhiko ; Izawa, Shoichiro ; Ohkura, Tsuyoshi ; Ohkura, Hiroko ; Ishiguro, Kiyosuke ; Yoshida, Akio ; Takiyama, Yumi ; Haneda, Masakazu ; Shigemasa, Chiaki ; Yamamoto, Kazuhiro ; Taniguchi, Shin-ichi
Publisher:England: BioMed Central Ltd
Journal title:BMC endocrine disorders, 2014-07, Vol.14 (1), p.52-52, Article 52
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ReportsFull Text
Hypoxia in diabetic kidneys
Author / Creator:Takiyama, Yumi ; Haneda, Masakazu
Publisher:John Wiley & Sons, Inc
Journal title:BioMed Research International, 2014
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ReportsFull Text
A case of insulinoma diagnosed postpartum with hypoglycemic symptoms that were masked during pregnancy
Author / Creator:Abe, Tomoe ; Takeda, Yasutaka ; Takiyama, Takao ; Sasaki, Ayaka ; Bessho, Ryoichi ; Sato, Mao ; Kitsunai, Hiroya ; Sakagami, Hidemitsu ; Abiko, Atsuko ; Imai, Koji ; Yuzawa, Sayaka ; Tanino, Mishie ; Takiyama, Yumi
Journal title:Clinical case reports, 2021, Vol.9 (4), p.1991-1998
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Hypoxia in Diabetic Kidneys

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Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells

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A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation

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A maternal high-fat diet induces fetal origins of NASH-HCC in mice

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The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study

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Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice

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Pancreatic glucose-dependent insulinotropic polypeptide (GIP) (1–30) expression is upregulated in diabetes and PEGylated GIP(1–30) can suppress the progression of low-dose-STZ-induced hyperglycaemia i...

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Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test

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A case of insulinoma diagnosed postpartum with hypoglycemic symptoms that were masked during pregnancy

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Alternative form of glucose‐dependent insulinotropic polypepide and its physiology

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High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells

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Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

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High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein

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Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin: A Possible Role of HIF-1α. Expression and Oxygen Metabolism

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Role of IGFBP7 in Diabetic Nephropathy: TGF-[beta]1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells

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Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

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Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin: A Possible Role of HIF-1[alpha] Expression and Oxygen Metabolism

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Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms

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Hypoxia in diabetic kidneys

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A case of insulinoma diagnosed postpartum with hypoglycemic symptoms that were masked during pregnancy

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