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ArticlesPeer ReviewedFull Text
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression
Author / Creator:Wang, Xinyi ; Sun, Guangqiang ; Feng, Teng ; Zhang, Jing ; Huang, Xun ; Wang, Tao ; Xie, Zuoquan ; Chu, Xingkun ; Yang, Jun ; Wang, Huan ; Chang, Shuaishuai ; Gong, Yanxue ; Ruan, Lingfei ; Zhang, Guanqun ; Yan, Siyuan ; Lian, Wen ; Du, Chen ; Yang, Dabing ; Zhang, Qingli ; Lin, Feifei ; Liu, Jia ; Zhang, Haiyan ; Ge, Changrong ; Xiao, Shifu ; Ding, Jian ; Geng, Meiyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2019-10, Vol.29 (10), p.787-803
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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
Author / Creator:Tian, Lin ; Goldstein, Amit ; Wang, Hai ; Ching Lo, Hin ; Sun Kim, Ik ; Welte, Thomas ; Sheng, Kuanwei ; Dobrolecki, Lacey E. ; Zhang, Xiaomei ; Putluri, Nagireddy ; Phung, Thuy L. ; Mani, Sendurai A. ; Stossi, Fabio ; Sreekumar, Arun ; Mancini, Michael A. ; Decker, William K. ; Zong, Chenghang ; Lewis, Michael T. ; Zhang, Xiang H.-F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-04, Vol.544 (7649), p.250-254
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IFN-γ-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells
Author / Creator:Ramstein, Joris ; Broos, Caroline E ; Simpson, Laura J ; Ansel, K Mark ; Sun, Sara A ; Ho, Melissa E ; Woodruff, Prescott G ; Bhakta, Nirav R ; Christian, Laura ; Nguyen, Christine P ; Antalek, Bobby J ; Benn, Bryan S ; Hendriks, Rudi W ; van den Blink, Bernt ; Kool, Mirjam ; Koth, Laura L
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2016-06, Vol.193 (11), p.1281-1291
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Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
Author / Creator:Peng, Dongjun ; Kryczek, Ilona ; Nagarsheth, Nisha ; Zhao, Lili ; Wei, Shuang ; Wang, Weimin ; Sun, Yuqing ; Zhao, Ende ; Vatan, Linda ; Szeliga, Wojciech ; Kotarski, Jan ; Tarkowski, Rafał ; Dou, Yali ; Cho, Kathleen ; Hensley-Alford, Sharon ; Munkarah, Adnan ; Liu, Rebecca ; Zou, Weiping
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-11, Vol.527 (7577), p.249-253
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Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
Author / Creator:Bernink, Jochem H ; Peters, Charlotte P ; Munneke, Marius ; te Velde, Anje A ; Meijer, Sybren L ; Weijer, Kees ; Hreggvidsdottir, Hulda S ; Heinsbroek, Sigrid E ; Legrand, Nicolas ; Buskens, Christianne J ; Bemelman, Willem A ; Mjösberg, Jenny M ; Spits, Hergen
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-03, Vol.14 (3), p.221-229
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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer
Author / Creator:Mace, Thomas A ; Shakya, Reena ; Pitarresi, Jason R ; Swanson, Benjamin ; McQuinn, Christopher W ; Loftus, Shannon ; Nordquist, Emily ; Cruz-Monserrate, Zobeida ; Yu, Lianbo ; Young, Gregory ; Zhong, Xiaoling ; Zimmers, Teresa A ; Ostrowski, Michael C ; Ludwig, Thomas ; Bloomston, Mark ; Bekaii-Saab, Tanios ; Lesinski, Gregory B
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2018-02, Vol.67 (2), p.320-332
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IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction
Author / Creator:Jabri, Bana ; Abadie, Valérie
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2015-12, Vol.15 (12), p.771-783
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The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity
Author / Creator:Itoh, Yuichiro ; Golden, Lisa C ; Itoh, Noriko ; Matsukawa, Macy Akiyo ; Ren, Emily ; Tse, Vincent ; Arnold, Arthur P ; Voskuhl, Rhonda R
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-09, Vol.129 (9), p.3852-3863
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ArticlesPeer ReviewedFull Text
Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function
Author / Creator:Bailis, Will ; Shyer, Justin A. ; Zhao, Jun ; Canaveras, Juan Carlos Garcia ; Al Khazal, Fatimah J. ; Qu, Rihao ; Steach, Holly R. ; Bielecki, Piotr ; Khan, Omair ; Jackson, Ruaidhri ; Kluger, Yuval ; Maher, Louis J. ; Rabinowitz, Joshua ; Craft, Joe ; Flavell, Richard A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7765), p.403-407
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ArticlesPeer ReviewedFull Text
Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis
Author / Creator:Chen, Liang ; Sun, Mingming ; Wu, Wei ; Yang, Wenjing ; Huang, Xiangsheng ; Xiao, Yi ; Ma, Chunyan ; Xu, Leiqi ; Yao, Suxia ; Liu, Zhanju ; Cong, Yingzi
Publisher:England: Oxford University Press
Journal title:Inflammatory bowel diseases, 2019-09, Vol.25 (9), p.1450-1461
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ArticlesPeer ReviewedFull Text
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis
Author / Creator:Comito, G. ; Iscaro, A. ; Bacci, M. ; Morandi, A. ; Ippolito, L. ; Parri, M. ; Montagnani, I. ; Raspollini, M. R. ; Serni, S. ; Simeoni, L. ; Giannoni, E. ; Chiarugi, P.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2019-05, Vol.38 (19), p.3681-3695
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ArticlesPeer ReviewedFull Text
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
Author / Creator:Perucha, Esperanza ; Melchiotti, Rossella ; Bibby, Jack A ; Wu, Wing ; Frederiksen, Klaus Stensgaard ; Roberts, Ceri A. ; Hall, Zoe ; LeFriec, Gaelle ; Robertson, Kevin A. ; Lavender, Paul ; Gerwien, Jens Gammeltoft ; Taams, Leonie S. ; Griffin, Julian L. ; de Rinaldis, Emanuele ; van Baarsen, Lisa G. M. ; Kemper, Claudia ; Ghazal, Peter ; Cope, Andrew P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.498-498, Article 498
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ArticlesPeer ReviewedFull Text
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation
Author / Creator:Hu, Gangqing ; Tang, Qingsong ; Sharma, Suveena ; Yu, Fang ; Escobar, Thelma M ; Muljo, Stefan A ; Zhu, Jinfang ; Zhao, Keji
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-11, Vol.14 (11), p.1190-1198
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ArticlesPeer ReviewedFull Text
The Pathogenicity and Synergistic Action of Th1 and Th17 Cells in Inflammatory Bowel Diseases
Author / Creator:Cao, Hui ; Diao, Jun ; Liu, Huosheng ; Liu, Suxian ; Liu, Jun ; Yuan, Jianye ; Lin, Jiang
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2023-05, Vol.29 (5), p.818-829
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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
Author / Creator:Delgoffe, Greg M ; Pollizzi, Kristen N ; Waickman, Adam T ; Heikamp, Emily ; Meyers, David J ; Horton, Maureen R ; Xiao, Bo ; Worley, Paul F ; Powell, Jonathan D
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2011-04, Vol.12 (4), p.295-303
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Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis
Author / Creator:Nie, Hong ; Zheng, Yingxia ; Li, Runsheng ; Guo, Taylor B ; He, Dongyi ; Fang, Lei ; Liu, Xuebin ; Xiao, Lianbo ; Chen, Xi ; Wan, Bing ; Chin, Y Eugene ; Zhang, Jingwu Z
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-03, Vol.19 (3), p.322-328
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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
Author / Creator:El-Behi, Mohamed ; Ciric, Bogoljub ; Dai, Hong ; Yan, Yaping ; Cullimore, Melissa ; Safavi, Farinaz ; Zhang, Guang-Xian ; Dittel, Bonnie N ; Rostami, Abdolmohamad
Publisher:United States
Journal title:Nature immunology, 2011-06, Vol.12 (6), p.568
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ArticlesPeer ReviewedFull Text
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Author / Creator:Minns, Danielle ; Smith, Katie J. ; Alessandrini, Virginia ; Hardisty, Gareth ; Melrose, Lauren ; Jackson-Jones, Lucy ; MacDonald, Andrew S. ; Davidson, Donald J. ; Gwyer Findlay, Emily
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1285-1285, Article 1285
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T(H)1 cells control themselves by producing interleukin-10
Author / Creator:O'Garra, Anne ; Vieira, Paulo
Publisher:England: Nature Publishing Group
Journal title:Nature reviews. Immunology, 2007-06, Vol.7 (6), p.425-428
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ArticlesPeer ReviewedFull Text
The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour
Author / Creator:Teoh, Tiong Ghee ; Yap, Xiao J. ; MacIntyre, David A. ; Sykes, Lynne ; Bennett, Phillip R.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Mediators of inflammation, 2012-01, Vol.2012 (2012), p.1-12
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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

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IFN-γ-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells

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Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

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Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

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IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction

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The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity

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Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

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Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis

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Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis

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The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

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Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

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The Pathogenicity and Synergistic Action of Th1 and Th17 Cells in Inflammatory Bowel Diseases

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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

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Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

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The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

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T(H)1 cells control themselves by producing interleukin-10

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The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour

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