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133 results for Thymidine+Phosphorylase+-+metabolism

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Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil
Author / Creator:Yang, Bingxue ; Xie, Xinran ; Lv, Dazhao ; Hu, Jiajun ; Chen, Yuyun ; Wu, Zhaoyu ; Luo, Shuyue ; Zhang, Shiyi
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2023-01, Vol.128 (2), p.219-231
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Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes
Author / Creator:Gautheron, Jérémie ; Lima, Lara ; Akinci, Baris ; Zammouri, Jamila ; Auclair, Martine ; Ucar, Sema Kalkan ; Ozen, Samim ; Altay, Canan ; Bax, Bridget E ; Nemazanyy, Ivan ; Lenoir, Véronique ; Prip-Buus, Carina ; Acquaviva-Bourdain, Cécile ; Lascols, Olivier ; Fève, Bruno ; Vigouroux, Corinne ; Noel, Esther ; Jéru, Isabelle
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2022-03, Vol.20 (1), p.95-95, Article 95
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Proteomic profiling of gliomas unveils immune and metabolism-driven subtypes with implications for anti-nucleotide metabolism therapy
Author / Creator:Zhang, Jinsen ; Sun, Rui ; Lyu, Yingying ; Liu, Chaxian ; Liu, Ying ; Feng, Yuan ; Fu, Minjie ; Wong, Peter Jih Cheng ; Du, Zunguo ; Qiu, Tianming ; Zhang, Yi ; Zhuang, Dongxiao ; Qin, Zhiyong ; Yao, Yu ; Zhu, Wei ; Guo, Tiannan ; Hua, Wei ; Yang, Hui ; Mao, Ying
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.10005-15, Article 10005
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Cachexia and efficiency of trifluridine/thymidine phosphorylase inhibitor + bevacizumab in metastatic colorectal cancer
Author / Creator:Shibutani, Masatsune ; Tanda, Hideki ; Seki, Yuki ; Kashiwagi, Shinichiro ; Nishiyama, Tsuyoshi ; Fukui, Yasuhiro ; Imanishi, Daiki ; Kasashima, Hiroaki ; Fukuoka, Tatsunari ; Maeda, Kiyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.25884-10, Article 25884
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Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab
Author / Creator:Shibutani, Masatsune ; Tanda, Hideki ; Kasashima, Hiroaki ; Fukuoka, Tatsunari ; Kashiwagi, Shinichiro ; Maeda, Kiyoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.553-7, Article 553
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Thymidine phosphorylase as a molecular target for quercetin-incorporated collagen matrix in the prevention of hand-foot syndrome induced by capecitabine in rats
Author / Creator:Mashaly, Maryam E ; Kotb, Hams M ; Abdin, Amany A ; Hedya, Sabiha E
Publisher:Canada: NRC Research Press
Journal title:Canadian journal of physiology and pharmacology, 2023-07, Vol.101 (7), p.340-348
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Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE
Author / Creator:Du, Jixiang ; Liu, Fuchen ; Liu, Xihan ; Zhao, Dandan ; Wang, Dongdong ; Sun, Hongsheng ; Yan, Chuanzhu ; Zhao, Yuying
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2024-05, Vol.22 (1), p.449-19, Article 449
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Gastrointestinal Dysmotility in MNGIE: from thymidine phosphorylase enzyme deficiency to altered interstitial cells of Cajal
Author / Creator:Yadak, Rana ; Breur, Marjolein ; Bugiani, Marianna
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2019-02, Vol.14 (1), p.33-33, Article 33
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Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies
Author / Creator:Javaid, Sumaira ; Shaikh, Muniza ; Fatima, Narjis ; Choudhary, M Iqbal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-11, Vol.14 (11), p.e0225056
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Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study
Author / Creator:Aknin, Karen ; Bontemps, Alexis ; Farce, Amaury ; Merlet, Eric ; Belmont, Philippe ; Helissey, Philippe ; Chavatte, Philippe ; Sari, Marie-Agnès ; Giorgi-Renault, Sylviane ; Desbène-Finck, Stéphanie
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.252-268
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Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: In vitro, kinetic, and in silico studies
Author / Creator:Javaid, Sumaira ; Saad, Syed Muhammad ; Zafar, Humaira ; Malik, Rizwana ; Khan, Khalid Mohammed ; Choudhary, M Iqbal ; Rahman, Atta-Ur
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227549
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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study
Author / Creator:Zaman, Khalid ; Rahim, Fazal ; Taha, Muhammad ; Wadood, Abdul ; Shah, Syed Adnan Ali ; Ahmed, Qamar Uddin ; Zakaria, Zainul Amiruddin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-11, Vol.9 (1), p.16015-11, Article 16015
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The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes
Author / Creator:Joyo, Yuji ; Kawaguchi, Yohei ; Yonezu, Hiroki ; Senda, Hiroya ; Yasuma, Sanshiro ; Shiraga, Hiroo ; Nozaki, Masahiro ; Aoyama, Mineyoshi ; Asai, Kiyofumi ; Murakami, Hideki ; Waguri-Nagaya, Yuko
Publisher:New York: Springer US
Journal title:Immunologic research, 2022-04, Vol.70 (2), p.208-215
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Novel Mutations of the TYMP Gene in Mitochondrial Neurogastrointestinal Encephalomyopathy: Case Series and Literature Review
Author / Creator:Mojtabavi, Helia ; Fatehi, Farzad ; Shahkarami, Sepideh ; Rezaei, Nima ; Nafissi, Shahriar
Publisher:New York: Springer US
Journal title:Journal of molecular neuroscience, 2021-12, Vol.71 (12), p.2526-2533
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Granulocyte-Colony Stimulating Factor related pathways tested on an endometrial ex-vivo model
Author / Creator:Rahmati, Mona ; Petitbarat, Marie ; Dubanchet, Sylvie ; Bensussan, Armand ; Chaouat, Gerard ; Ledee, Nathalie
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-10, Vol.9 (9), p.e102286
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Bevacizumab‐enhanced antitumor effect of 5‐fluorouracil via upregulation of thymidine phosphorylase through vascular endothelial growth factor A/vascular endothelial growth factor receptor 2‐specifici...
Author / Creator:Liu, Wenyue ; Zhang, Jingwei ; Yao, Xuequan ; Jiang, Chao ; Ni, Ping ; Cheng, Lingge ; Liu, Jiali ; Ni, Suiying ; Chen, Qianying ; Li, Qingran ; Zhou, Kai ; Wang, Guangji ; Zhou, Fang
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-10, Vol.109 (10), p.3294-3304
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Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry
Author / Creator:Lee, James J ; Seraj, Jabed ; Yoshida, Kenichiro ; Mizuguchi, Hirokazu ; Strychor, Sandra ; Fiejdasz, Jillian ; Faulkner, Tyeler ; Parise, Robert A ; Fawcett, Patrick ; Pollice, Laura ; Mason, Scott ; Hague, Jeremy ; Croft, Marie ; Nugteren, James ; Tedder, Charles ; Sun, Weijing ; Chu, Edward ; Beumer, Jan Hendrik
Publisher:Germany
Journal title:Cancer chemotherapy and pharmacology, 2016-03, Vol.77 (3), p.515-526
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Thymidine phosphorylase promotes metastasis and serves as a marker of poor prognosis in hepatocellular carcinoma
Author / Creator:Zhang, Qiang ; Zhang, Yang ; Hu, Xuejiao ; Qin, Yuan ; Zhong, Weilong ; Meng, Jing ; Xiao, Ting ; Zhang, Chunhong ; Li, Meng ; Chen, Shuang ; Liu, Huijuan ; Liu, Yanrong ; Sun, Tao ; Yang, Cheng
Publisher:New York: Nature Publishing Group US
Journal title:Laboratory investigation, 2017-08, Vol.97 (8), p.903-912
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5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine
Author / Creator:Yoshida, Yoichiro ; Hashimoto, Yasuhiro ; Miyazaki, Makoto ; Aisu, Naoya ; Yamada, Teppei ; Kajitani, Ryuji ; Munechika, Taro ; Matsumoto, Yoshiko ; Nagano, Hideki ; Shimaoka, Hideki ; Komono, Akira ; Sakamoto, Ryohei ; Yoshimatsu, Gumpei ; Yoshimura, Fumihiro ; Kiyomi, Fumiaki ; Hasegawa, Suguru
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.2711, Article 2711
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Thymidine phosphorylase induction by ionizing radiation antagonizes 5-fluorouracil resistance in human ductal pancreatic adenocarcinoma
Author / Creator:Lee, Lucas D. ; Pozios, Ioannis ; Liu, Verena ; Nachbichler, Silke B. ; Böhmer, Dirk ; Kamphues, Carsten ; Beyer, Katharina ; Bruns, Christiane J. ; Kreis, Martin E. ; Seeliger, Hendrik
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Radiation and environmental biophysics, 2022-05, Vol.61 (2), p.255-262
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Showing 1 to 20 of 133 results

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Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil

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Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

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Proteomic profiling of gliomas unveils immune and metabolism-driven subtypes with implications for anti-nucleotide metabolism therapy

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Cachexia and efficiency of trifluridine/thymidine phosphorylase inhibitor + bevacizumab in metastatic colorectal cancer

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Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab

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Thymidine phosphorylase as a molecular target for quercetin-incorporated collagen matrix in the prevention of hand-foot syndrome induced by capecitabine in rats

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Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE

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Gastrointestinal Dysmotility in MNGIE: from thymidine phosphorylase enzyme deficiency to altered interstitial cells of Cajal

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Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies

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Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study

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Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: In vitro, kinetic, and in silico studies

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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study

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The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes

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Novel Mutations of the TYMP Gene in Mitochondrial Neurogastrointestinal Encephalomyopathy: Case Series and Literature Review

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Granulocyte-Colony Stimulating Factor related pathways tested on an endometrial ex-vivo model

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Bevacizumab‐enhanced antitumor effect of 5‐fluorouracil via upregulation of thymidine phosphorylase through vascular endothelial growth factor A/vascular endothelial growth factor receptor 2‐specifici...

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Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry

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Thymidine phosphorylase promotes metastasis and serves as a marker of poor prognosis in hepatocellular carcinoma

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5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine

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Thymidine phosphorylase induction by ionizing radiation antagonizes 5-fluorouracil resistance in human ductal pancreatic adenocarcinoma

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