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ArticlesPeer ReviewedFull Text
The emergence of transcriptional identity in somatosensory neurons
Author / Creator:Sharma, Nikhil ; Flaherty, Kali ; Lezgiyeva, Karina ; Wagner, Daniel E. ; Klein, Allon M. ; Ginty, David D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-01, Vol.577 (7790), p.392-398
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POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism
Author / Creator:Yu, Haoze V. ; Tao, Litao ; Llamas, Juan ; Wang, Xizi ; Nguyen, John D. ; Trecek, Talon ; Segil, Neil
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1-12
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Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals
Author / Creator:Iyer, Amrita A ; Hosamani, Ishwar ; Nguyen, John D ; Cai, Tiantian ; Singh, Sunita ; McGovern, Melissa M ; Beyer, Lisa ; Zhang, Hongyuan ; Jen, Hsin-I ; Yousaf, Rizwan ; Birol, Onur ; Sun, Jenny J ; Ray, Russell S ; Raphael, Yehoash ; Segil, Neil ; Groves, Andrew K
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2022-11, Vol.11
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Repair of surviving hair cells in the damaged mouse utricle
Author / Creator:Kim, Grace S. ; Wang, Tian ; Sayyid, Zahra N. ; Fuhriman, Jessica ; Jones, Sherri M. ; Cheng, Alan G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (15), p.1-12
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Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses
Author / Creator:Singh, Sushma ; Penney, Cindy ; Griffin, Anne ; Woodland, Geoffrey ; Werdyani, Salem ; Benteau, Tammy A. ; Abdelfatah, Nelly ; Squires, Jessica ; King, Beverly ; Houston, Jim ; Dyer, Matthew J. ; Roslin, Nicole M. ; Vincent, Daniel ; Marquis, Pascale ; O’Rielly, Darren D. ; Hodgkinson, Kathy ; Burt, Taylor ; Baker, Ashley ; Stanton, Susan G. ; Young, Terry-Lynn
Publisher:England: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2023-07, Vol.31 (7), p.815-823
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Norrie disease protein is essential for cochlear hair cell maturation
Author / Creator:Hayashi, Yushi ; Chiang, Hao ; Tian, ChunJie ; Indzhykulian, Artur A. ; Edge, Albert S. B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1-12
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Whole Number, Distribution and Co-Expression of Brn3 Transcription Factors in Retinal Ganglion Cells of Adult Albino and Pigmented Rats
Author / Creator:Nadal-Nicolás, Francisco M. ; Jiménez-López, Manuel ; Salinas-Navarro, Manuel ; Sobrado-Calvo, Paloma ; Alburquerque-Béjar, Juan J. ; Vidal-Sanz, Manuel ; Agudo-Barriuso, Marta
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e49830-e49830
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Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15
Author / Creator:Pan, Jianyan ; Teng, Hua ; Liu, Fang ; Chen, Siyi ; Liu, Yaning ; Teng, Yanling ; Liang, Desheng ; Li, Zhuo ; Wu, Lingqian
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.1981-11, Article 1981
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Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival
Author / Creator:Wang, Guangqin ; Gu, Yunpeng ; Liu, Zhiyong
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2024-03, Vol.12
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AAV‐mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration
Author / Creator:Zhang, Liyan ; Chen, Xin ; Wang, Xinlin ; Zhou, Yinyi ; Fang, Yuan ; Gu, Xingliang ; Zhang, Ziyu ; Sun, Qiuhan ; Li, Nianci ; Xu, Lei ; Tan, Fangzhi ; Chai, Renjie ; Qi, Jieyu
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2024-08, Vol.11 (29), p.e2304551-n/a
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In Vivo Generation of Immature Inner Hair Cells in Neonatal Mouse Cochleae by Ectopic Atoh1 Expression
Author / Creator:Liu, Zhiyong ; Fang, Jie ; Dearman, Jennifer ; Zhang, Lingli ; Zuo, Jian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-02, Vol.9 (2), p.e89377-e89377
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Aldh inhibitor restores auditory function in a mouse model of human deafness
Author / Creator:Zhu, Guang-Jie ; Gong, Sihao ; Ma, Deng-Bin ; Tao, Tao ; He, Wei-Qi ; Zhang, Linqing ; Wang, Fang ; Qian, Xiao-Yun ; Zhou, Han ; Fan, Chi ; Wang, Pei ; Chen, Xin ; Zhao, Wei ; Sun, Jie ; Chen, Huaqun ; Wang, Ye ; Gao, Xiang ; Zuo, Jian ; Zhu, Min-Sheng ; Gao, Xia ; Wan, Guoqiang
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2020-09, Vol.16 (9), p.e1009040
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POU4F3 mutation screening in Japanese hearing loss patients: Massively parallel DNA sequencing-based analysis identified novel variants associated with autosomal dominant hearing loss
Author / Creator:Kitano, Tomohiro ; Miyagawa, Maiko ; Nishio, Shin-ya ; Moteki, Hideaki ; Oda, Kiyoshi ; Ohyama, Kenji ; Miyazaki, Hiromitsu ; Hidaka, Hiroshi ; Nakamura, Ken-ichi ; Murata, Takaaki ; Matsuoka, Rina ; Ohta, Yoko ; Nishiyama, Nobuhiro ; Kumakawa, Kozo ; Furutate, Sakiko ; Iwasaki, Satoshi ; Yamada, Takechiyo ; Ohta, Yumi ; Uehara, Natsumi ; Noguchi, Yoshihiro ; Usami, Shin-ichi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-05, Vol.12 (5), p.e0177636-e0177636
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A Novel Atoh1 “Self-Terminating” Mouse Model Reveals the Necessity of Proper Atoh1 Level and Duration for Hair Cell Differentiation and Viability
Author / Creator:Pan, Ning ; Jahan, Israt ; Kersigo, Jennifer ; Duncan, Jeremy S. ; Kopecky, Benjamin ; Fritzsch, Bernd
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-01, Vol.7 (1), p.e30358-e30358
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Identification of two novel mutations in POU4F3 gene associated with autosomal dominant hearing loss in Chinese families
Author / Creator:Bai, Xiaohui ; Zhang, Fengguo ; Xiao, Yun ; Jin, Yu ; Zheng, Qingyin ; Wang, Haibo ; Xu, Lei
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2020-06, Vol.24 (12), p.6978-6987
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ArticlesPeer ReviewedFull Text
Transcription factor induced conversion of human fibroblasts towards the hair cell lineage
Author / Creator:Duran Alonso, María Beatriz ; Lopez Hernandez, Iris ; de la Fuente, Miguel Angel ; Garcia-Sancho, Javier ; Giraldez, Fernando ; Schimmang, Thomas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-07, Vol.13 (7), p.e0200210
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Functional Correlation of Two Novel Nonsense POU4F3 Mutations Causing Late‐Onset Progressive Nonsyndromic Hearing Loss in DFNA15 Families
Author / Creator:Zhang, Tianyang ; Wang, Wei ; Zhang, Luping ; He, Jingchun
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular genetics & genomic medicine, 2025-05, Vol.13 (5), p.e70100-n/a
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Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: a cross-sectional, multi-center next-generation sequencing study
Author / Creator:Mutai, Hideki ; Suzuki, Naohiro ; Shimizu, Atsushi ; Torii, Chiharu ; Namba, Kazunori ; Morimoto, Noriko ; Kudoh, Jun ; Kaga, Kimitaka ; Kosaki, Kenjiro ; Matsunaga, Tatsuo
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2013-10, Vol.8 (1), p.172-172, Article 172
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A novel missense variant in the nuclear localization signal of POU4F3 causes autosomal dominant non-syndromic hearing loss
Author / Creator:Lin, Yin-Hung ; Lin, Yi-Hsin ; Lu, Ying-Chang ; Liu, Tien-Chen ; Chen, Chien-Yu ; Hsu, Chuan-Jen ; Chen, Pei-Lung ; Wu, Chen-Chi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.7551-6, Article 7551
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Exome sequencing identifies POU4F3 as the causative gene for a large Chinese family with non-syndromic hearing loss
Author / Creator:Cai, Xin Zhang ; Li, Ying ; Xia, Lu ; Peng, Yu ; He, Chu Feng ; Jiang, Lu ; Feng, Yong ; Xia, Kun ; Liu, Xue Zhong ; Mei, Ling Yun ; Hu, Zheng Mao
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2017-02, Vol.62 (2), p.317-320
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Showing 1 to 20 of 46 results

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The emergence of transcriptional identity in somatosensory neurons

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POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism

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Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

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Repair of surviving hair cells in the damaged mouse utricle

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Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses

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Norrie disease protein is essential for cochlear hair cell maturation

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Whole Number, Distribution and Co-Expression of Brn3 Transcription Factors in Retinal Ganglion Cells of Adult Albino and Pigmented Rats

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Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15

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Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival

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AAV‐mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration

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In Vivo Generation of Immature Inner Hair Cells in Neonatal Mouse Cochleae by Ectopic Atoh1 Expression

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Aldh inhibitor restores auditory function in a mouse model of human deafness

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POU4F3 mutation screening in Japanese hearing loss patients: Massively parallel DNA sequencing-based analysis identified novel variants associated with autosomal dominant hearing loss

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A Novel Atoh1 “Self-Terminating” Mouse Model Reveals the Necessity of Proper Atoh1 Level and Duration for Hair Cell Differentiation and Viability

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Identification of two novel mutations in POU4F3 gene associated with autosomal dominant hearing loss in Chinese families

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Transcription factor induced conversion of human fibroblasts towards the hair cell lineage

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Functional Correlation of Two Novel Nonsense POU4F3 Mutations Causing Late‐Onset Progressive Nonsyndromic Hearing Loss in DFNA15 Families

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Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: a cross-sectional, multi-center next-generation sequencing study

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A novel missense variant in the nuclear localization signal of POU4F3 causes autosomal dominant non-syndromic hearing loss

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Exome sequencing identifies POU4F3 as the causative gene for a large Chinese family with non-syndromic hearing loss

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