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Newsletter articlesFull Text
Biotechnology; Future Anti-Cancer Therapeutics Revolve Around Gene Therapy Approaches
Publisher:Atlanta: NewsRx
Journal title:AIDS Weekly Plus, 1995, p.2
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ArticlesPeer ReviewedFull Text
NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy
Author / Creator:Suck, Garnet ; Odendahl, Marcus ; Nowakowska, Paulina ; Seidl, Christian ; Wels, Winfried S. ; Klingemann, Hans G. ; Tonn, Torsten
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2016-04, Vol.65 (4), p.485-492
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ArticlesPeer ReviewedFull Text
CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies
Author / Creator:Romanski, Annette ; Uherek, Christoph ; Bug, Gesine ; Seifried, Erhard ; Klingemann, Hans ; Wels, Winfried S. ; Ottmann, Oliver G. ; Tonn, Torsten
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2016-07, Vol.20 (7), p.1287-1294
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ArticlesPeer ReviewedFull Text
Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies
Author / Creator:Nowakowska, Paulina ; Romanski, Annette ; Miller, Nicole ; Odendahl, Marcus ; Bonig, Halvard ; Zhang, Congcong ; Seifried, Erhard ; Wels, Winfried S. ; Tonn, Torsten
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2018-01, Vol.67 (1), p.25-38
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ArticlesPeer ReviewedFull Text
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
Author / Creator:Hegde, Meenakshi ; Joseph, Sujith K. ; Pashankar, Farzana ; DeRenzo, Christopher ; Sanber, Khaled ; Navai, Shoba ; Byrd, Tiara T. ; Hicks, John ; Xu, Mina L. ; Gerken, Claudia ; Kalra, Mamta ; Robertson, Catherine ; Zhang, Huimin ; Shree, Ankita ; Mehta, Birju ; Dakhova, Olga ; Salsman, Vita S. ; Grilley, Bambi ; Gee, Adrian ; Dotti, Gianpietro ; Heslop, Helen E. ; Brenner, Malcolm K. ; Wels, Winfried S. ; Gottschalk, Stephen ; Ahmed, Nabil
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3549-3549, Article 3549
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ArticlesPeer ReviewedFull Text
In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome
Author / Creator:Pfeiffer, Anett ; Thalheimer, Frederic B ; Hartmann, Sylvia ; Frank, Annika M ; Bender, Ruben R ; Danisch, Simon ; Costa, Caroline ; Wels, Winfried S ; Modlich, Ute ; Stripecke, Renata ; Verhoeyen, Els ; Buchholz, Christian J
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2018-11, Vol.10 (11), p.1-n/a
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ArticlesPeer ReviewedFull Text
TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy
Author / Creator:Grada, Zakaria ; Hegde, Meenakshi ; Byrd, Tiara ; Shaffer, Donald R ; Ghazi, Alexia ; Brawley, Vita S ; Corder, Amanda ; Schönfeld, Kurt ; Koch, Joachim ; Dotti, Gianpietro ; Heslop, Helen E ; Gottschalk, Stephen ; Wels, Winfried S ; Baker, Matthew L ; Ahmed, Nabil
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2013, Vol.2 (7), p.e105-e105, Article e105
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ArticlesPeer ReviewedFull Text
Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Author / Creator:Zhang, Congcong ; Röder, Jasmin ; Scherer, Anne ; Bodden, Malena ; Pfeifer Serrahima, Jordi ; Bhatti, Anita ; Waldmann, Anja ; Müller, Nina ; Oberoi, Pranav ; Wels, Winfried S
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-10, Vol.9 (10), p.e002980
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ArticlesPeer ReviewedFull Text
Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells
Author / Creator:Müller, Tina ; Uherek, Christoph ; Maki, Guitta ; Chow, Kai Uwe ; Schimpf, Annemarie ; Klingemann, Hans-Georg ; Tonn, Torsten ; Wels, Winfried S.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer Immunology, Immunotherapy, 2008-03, Vol.57 (3), p.411-423
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ArticlesPeer ReviewedFull Text
Vaccination Directed against the Human Endogenous Retrovirus-K Envelope Protein Inhibits Tumor Growth in a Murine Model System
Author / Creator:Kraus, Benjamin ; Fischer, Katrin ; Büchner, Sarah M. ; Wels, Winfried S. ; Löwer, Roswitha ; Sliva, Katja ; Schnierle, Barbara S.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-08, Vol.8 (8), p.e72756-e72756
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ArticlesPeer ReviewedFull Text
Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity
Author / Creator:Oberoi, Pranav ; Kamenjarin, Kathrina ; Villena Ossa, Jose Francisco ; Uherek, Barbara ; Bönig, Halvard ; Wels, Winfried S.
Publisher:Switzerland: MDPI
Journal title:Cells (Basel, Switzerland), 2020-03, Vol.9 (4), p.811
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ArticlesPeer ReviewedFull Text
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Author / Creator:Eitler, Jiri ; Rackwitz, Wiebke ; Wotschel, Natalie ; Gudipati, Venugopal ; Murali Shankar, Nivedha ; Sidorenkova, Anastasia ; Huppa, Johannes B ; Ortiz-Montero, Paola ; Opitz, Corinna ; Künzel, Stephan R ; Michen, Susanne ; Temme, Achim ; Loureiro, Liliana Rodrigues ; Feldmann, Anja ; Bachmann, Michael ; Boissel, Laurent ; Klingemann, Hans ; Wels, Winfried S ; Tonn, Torsten
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-02, Vol.12 (2), p.e008155
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ArticlesPeer ReviewedFull Text
Dual Targeting of Glioblastoma Cells with Bispecific Killer Cell Engagers Directed to EGFR and ErbB2 (HER2) Facilitates Effective Elimination by NKG2D-CAR-Engineered NK Cells
Author / Creator:Kiefer, Anne ; Prüfer, Maren ; Röder, Jasmin ; Pfeifer Serrahima, Jordi ; Bodden, Malena ; Kühnel, Ines ; Oberoi, Pranav ; Wels, Winfried S.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-01, Vol.13 (3), p.246
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ArticlesPeer ReviewedFull Text
Expression of Potential Targets for Cell-Based Therapies on Melanoma Cells
Author / Creator:Strobel, Sophia B. ; Machiraju, Devayani ; Hülsmeyer, Ingrid ; Becker, Jürgen C. ; Paschen, Annette ; Jäger, Dirk ; Wels, Winfried S. ; Bachmann, Michael ; Hassel, Jessica C.
Publisher:Switzerland: MDPI AG
Journal title:Life (Basel, Switzerland), 2021-03, Vol.11 (4), p.269
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ArticlesPeer ReviewedFull Text
Tailoring cells for clinical needs: Meeting report from the Advanced Therapy in Healthcare symposium (October 28–29 2017, Doha, Qatar)
Author / Creator:Deola, Sara ; Guerrouahen, Bella S. ; Sidahmed, Heba ; Al-Mohannadi, Anjud ; Elnaggar, Muhammad ; Elsadig, Ramaz ; Abdelalim, Essam M. ; Petrovski, Goran ; Gadina, Massimo ; Thrasher, Adrian ; Wels, Winfried S. ; Hunger, Stephen P. ; Wang, Ena ; Marincola, Francesco M. ; Maccalli, Cristina ; Cugno, Chiara
Publisher:England: BioMed Central
Journal title:Journal of translational medicine, 2018-10, Vol.16 (1), p.276-276, Article 276
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ArticlesPeer ReviewedFull Text
Tandem CAR T cells targeting HER2 and IL13R alpha 2 mitigate tumor antigen escape
Author / Creator:Hegde, Meenakshi ; Mukherjee, Malini ; Grada, Zakaria ; Pignata, Antonella ; Landi, Daniel ; Navai, Shoba A ; Wakefield, Amanda ; Fousek, Kristen ; Bielamowicz, Kevin ; Chow, Kevin K H ; Brawley, Vita S ; Byrd, Tiara T ; Krebs, Simone ; Gottschalk, Stephen ; Wels, Winfried S ; Baker, Matthew L ; Dotti, Gianpietro ; Mamonkin, Maksim ; Brenner, Malcolm K ; Orange, Jordan S ; Ahmed, Nabil
Journal title:The Journal of clinical investigation, 2016-08, Vol.126 (8), p.3036-3036
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ArticlesPeer ReviewedFull Text
Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
Author / Creator:Hegde, Meenakshi ; Mukherjee, Malini ; Grada, Zakaria ; Pignata, Antonella ; Landi, Daniel ; Navai, Shoba A. ; Wakefield, Amanda ; Fousek, Kristen ; Bielamowicz, Kevin ; Chow, Kevin K.H. ; Brawley, Vita S. ; Byrd, Tiara T. ; Krebs, Simone ; Gottschalk, Stephen ; Wels, Winfried S. ; Baker, Matthew L. ; Dotti, Gianpietro ; Mamonkin, Maksim ; Brenner, Malcolm K. ; Orange, Jordan S. ; Ahmed, Nabil
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-08, Vol.126 (8), p.3036-3052
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ArticlesPeer ReviewedFull Text
Maltose-Binding Protein Enhances Secretion of Recombinant Human Granzyme B Accompanied by In Vivo Processing of a Precursor MBP Fusion Protein
Author / Creator:Dälken, Benjamin ; Jabulowsky, Robert A. ; Oberoi, Pranav ; Benhar, Itai ; Wels, Winfried S.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-12, Vol.5 (12), p.e14404
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ArticlesPeer ReviewedFull Text
Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
Author / Creator:Sahm, Christiane ; Schönfeld, Kurt ; Wels, Winfried S.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer Immunology, Immunotherapy, 2012-09, Vol.61 (9), p.1451-1461
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ArticlesPeer ReviewedFull Text
EGFR-Targeted Granzyme B Expressed in NK Cells Enhances Natural Cytotoxicity and Mediates Specific Killing of Tumor Cells
Author / Creator:Oberoi, Pranav ; Jabulowsky, Robert A. ; Bähr-Mahmud, Hayat ; Wels, Winfried S.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e61267
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Showing 1 to 20 of 51 results

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Biotechnology; Future Anti-Cancer Therapeutics Revolve Around Gene Therapy Approaches

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NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy

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CD19‐CAR engineered NK‐92 cells are sufficient to overcome NK cell resistance in B‐cell malignancies

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Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies

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Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma

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In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

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TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy

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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity

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Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells

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Vaccination Directed against the Human Endogenous Retrovirus-K Envelope Protein Inhibits Tumor Growth in a Murine Model System

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Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity

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CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation

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Dual Targeting of Glioblastoma Cells with Bispecific Killer Cell Engagers Directed to EGFR and ErbB2 (HER2) Facilitates Effective Elimination by NKG2D-CAR-Engineered NK Cells

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Expression of Potential Targets for Cell-Based Therapies on Melanoma Cells

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Tailoring cells for clinical needs: Meeting report from the Advanced Therapy in Healthcare symposium (October 28–29 2017, Doha, Qatar)

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Tandem CAR T cells targeting HER2 and IL13R alpha 2 mitigate tumor antigen escape

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Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

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Maltose-Binding Protein Enhances Secretion of Recombinant Human Granzyme B Accompanied by In Vivo Processing of a Precursor MBP Fusion Protein

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Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor

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EGFR-Targeted Granzyme B Expressed in NK Cells Enhances Natural Cytotoxicity and Mediates Specific Killing of Tumor Cells

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