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ArticlesPeer ReviewedFull Text
Immune checkpoint inhibitors for refractory childhood cancers
Author / Creator:Widemann, Brigitte C
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-01, Vol.21 (1), p.14-15
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Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas
Author / Creator:Dombi, Eva ; Baldwin, Andrea ; Marcus, Leigh J ; Fisher, Michael J ; Weiss, Brian ; Kim, AeRang ; Whitcomb, Patricia ; Martin, Staci ; Aschbacher-Smith, Lindsey E ; Rizvi, Tilat A ; Wu, Jianqiang ; Ershler, Rachel ; Wolters, Pamela ; Therrien, Janet ; Glod, John ; Belasco, Jean B ; Schorry, Elizabeth ; Brofferio, Alessandra ; Starosta, Amy J ; Gillespie, Andrea ; Doyle, Austin L ; Ratner, Nancy ; Widemann, Brigitte C
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-12, Vol.375 (26), p.2550-2560
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Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study
Author / Creator:Szymanski, Jeffrey J ; Sundby, R Taylor ; Jones, Paul A ; Srihari, Divya ; Earland, Noah ; Harris, Peter K ; Feng, Wenjia ; Qaium, Faridi ; Lei, Haiyan ; Roberts, David ; Landeau, Michele ; Bell, Jamie ; Huang, Yi ; Hoffman, Leah ; Spencer, Melissa ; Spraker, Matthew B ; Ding, Li ; Widemann, Brigitte C ; Shern, Jack F ; Hirbe, Angela C ; Chaudhuri, Aadel A
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2021-08, Vol.18 (8), p.e1003734
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ArticlesPeer ReviewedFull Text
Selumetinib in Children with Inoperable Plexiform Neurofibromas
Author / Creator:Gross, Andrea M ; Wolters, Pamela L ; Dombi, Eva ; Baldwin, Andrea ; Whitcomb, Patricia ; Fisher, Michael J ; Weiss, Brian ; Kim, AeRang ; Bornhorst, Miriam ; Shah, Amish C ; Martin, Staci ; Roderick, Marie C ; Pichard, Dominique C ; Carbonell, Amanda ; Paul, Scott M ; Therrien, Janet ; Kapustina, Oxana ; Heisey, Kara ; Clapp, D. Wade ; Zhang, Chi ; Peer, Cody J ; Figg, William D ; Smith, Malcolm ; Glod, John ; Blakeley, Jaishri O ; Steinberg, Seth M ; Venzon, David J ; Doyle, L. Austin ; Widemann, Brigitte C
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2020-04, Vol.382 (15), p.1430-1442
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Safety and efficacy of low-dose sirolimus in the PIK3CA-related overgrowth spectrum
Author / Creator:Parker, Victoria E. R. ; Keppler-Noreuil, Kim M. ; Faivre, Laurence ; Luu, Maxime ; Oden, Neal L. ; De Silva, Leena ; Sapp, Julie C. ; Andrews, Katrina ; Bardou, Marc ; Chen, Kong Y. ; Darling, Thomas N. ; Gautier, Elodie ; Goldspiel, Barry R. ; Hadj-Rabia, Smail ; Harris, Julie ; Kounidas, Georgios ; Kumar, Parag ; Lindhurst, Marjorie J. ; Loffroy, Romaric ; Martin, Ludovic ; Phan, Alice ; Rother, Kristina I. ; Widemann, Brigitte C. ; Wolters, Pamela L. ; Coubes, Christine ; Pinson, Lucile ; Willems, Marjolaine ; Vincent-Delorme, Catherine ; Vabres, Pierre ; Semple, Robert K. ; Biesecker, Leslie G.
Publisher:New York: Nature Publishing Group US
Journal title:Genetics in medicine, 2019-05, Vol.21 (5), p.1189-1198
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ArticlesPeer ReviewedFull Text
Longitudinal association between executive function and academic achievement in children with neurofibromatosis type 1 and plexiform neurofibromas
Author / Creator:Hou, Yang ; Wu, Xian ; Allen, Taryn ; Toledo-Tamula, Mary Anne ; Martin, Staci ; Gillespie, Andy ; Goodwin, Anne ; Widemann, Brigitte C. ; Wolters, Pamela L.
Publisher:New York, USA: Cambridge University Press
Journal title:Journal of the International Neuropsychological Society, 2023-11, Vol.29 (9), p.839-849
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Low-Intensity Therapy in Adults with Burkitt's Lymphoma
Author / Creator:Dunleavy, Kieron ; Pittaluga, Stefania ; Shovlin, Margaret ; Steinberg, Seth M ; Cole, Diane ; Grant, Cliona ; Widemann, Brigitte ; Staudt, Louis M ; Jaffe, Elaine S ; Little, Richard F ; Wilson, Wyndham H
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-11, Vol.369 (20), p.1915-1925
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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
Author / Creator:Jessen, Walter J ; Miller, Shyra J ; Jousma, Edwin ; Wu, Jianqiang ; Rizvi, Tilat A ; Brundage, Meghan E ; Eaves, David ; Widemann, Brigitte ; Kim, Mi-Ok ; Dombi, Eva ; Sabo, Jessica ; Hardiman Dudley, Atira ; Niwa-Kawakita, Michiko ; Page, Grier P ; Giovannini, Marco ; Aronow, Bruce J ; Cripe, Timothy P ; Ratner, Nancy
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-01, Vol.123 (1), p.340-347
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ArticlesPeer ReviewedFull Text
Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
Author / Creator:Fisher, Michael J. ; Shih, Chie-Schin ; Rhodes, Steven D. ; Armstrong, Amy E. ; Wolters, Pamela L. ; Dombi, Eva ; Zhang, Chi ; Angus, Steven P. ; Johnson, Gary L. ; Packer, Roger J. ; Allen, Jeffrey C. ; Ullrich, Nicole J. ; Goldman, Stewart ; Gutmann, David H. ; Plotkin, Scott R. ; Rosser, Tena ; Robertson, Kent A. ; Widemann, Brigitte C. ; Smith, Abbi E. ; Bessler, Waylan K. ; He, Yongzheng ; Park, Su-Jung ; Mund, Julie A. ; Jiang, Li ; Bijangi-Vishehsaraei, Khadijeh ; Robinson, Coretta Thomas ; Cutter, Gary R. ; Korf, Bruce R. ; Blakeley, Jaishri O. ; Clapp, D. Wade
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-01, Vol.27 (1), p.165-173
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Outcome of Patients With Malignant Peripheral Nerve Sheath Tumors Enrolled on Sarcoma Alliance for Research Through Collaboration (SARC) Phase II Trials
Author / Creator:Akshintala, Srivandana ; Mallory, Nicole C ; Lu, Yao ; Ballman, Karla V ; Schuetze, Scott M ; Chugh, Rashmi ; Maki, Robert G ; Reinke, Denise K ; Widemann, Brigitte C ; Kim, AeRang
Publisher:US: Oxford University Press
Journal title:The oncologist (Dayton, Ohio), 2023-05, Vol.28 (5), p.453-459
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Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1
Author / Creator:Nguyen, Rosa ; Dombi, Eva ; Widemann, Brigitte C ; Solomon, Jeffrey ; Fuensterer, Carsten ; Kluwe, Lan ; Friedman, Jan M ; Mautner, Victor-Felix
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2012-10, Vol.7 (1), p.75-75
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The Landscape of US and Global Rare Tumor Research Programs: A Systematic Review
Author / Creator:Vivelo, Christina ; Reilly, Karlyne M ; Widemann, Brigitte C ; Wedekind, Mary Frances ; Painter, Corrie ; O’Neill, Allison F ; Mueller, Sabine ; Elemento, Olivier ; Gross, Andrea M ; Sandler, Abby B
Publisher:US: Oxford University Press
Journal title:The oncologist (Dayton, Ohio), 2024-02, Vol.29 (2), p.106-116
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Reporting of Racial and Ethnic Minority Representation in Early Phase Pediatric Oncology Clinical Trials
Author / Creator:Faruqi, Aiman J ; Ligon, John A ; Cohen, Julia W ; Akshintala, Srivandana ; Widemann, Brigitte C ; Shah, Nirali N
Publisher:US: Oxford University Press
Journal title:The oncologist (Dayton, Ohio), 2022-08, Vol.27 (8), p.e681-e682
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Characterization of spinal findings in children and adults with neurofibromatosis type 1 enrolled in a natural history study using magnetic resonance imaging
Author / Creator:Nguyen, Rosa ; Dombi, Eva ; Akshintala, Srivandana ; Baldwin, Andrea ; Widemann, Brigitte C.
Publisher:Boston: Springer US
Journal title:Journal of neuro-oncology, 2015-01, Vol.121 (1), p.209-215
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Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies
Author / Creator:Miettinen, Markku M. ; Viskochil, David ; Reilly, Karlyne M. ; Stewart, Douglas R. ; Kim, AeRang ; Widemann, Brigitte C.
Publisher:Cairo, Egypt: Hindawi Limiteds
Journal title:Complexity (New York, N.Y.), 2017, Vol.2017 (2017), p.1-10-015
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A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript
Author / Creator:Grohar, Patrick J. ; Glod, John ; Peer, Cody J. ; Sissung, Tristan M. ; Arnaldez, Fernanda I. ; Long, Lauren ; Figg, William D. ; Whitcomb, Patricia ; Helman, Lee J. ; Widemann, Brigitte C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2017-09, Vol.80 (3), p.645-652
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Psychosocial Characteristics and Experiences in Patients with Multiple Endocrine Neoplasia Type 2 (MEN2) and Medullary Thyroid Carcinoma (MTC)
Author / Creator:Lockridge, Robin ; Bedoya, Sima ; Allen, Taryn ; Widemann, Brigitte C ; Akshintala, Srivandana ; Glod, John ; Wiener, Lori
Publisher:Switzerland: MDPI AG
Journal title:Children (Basel), 2022-05, Vol.9 (6), p.774
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Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory sol...
Author / Creator:Fox, Elizabeth ; Widemann, Brigitte C. ; Pastakia, Devang ; Chen, Clara C. ; Yang, Sherry X. ; Cole, Diane ; Balis, Frank M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2015-12, Vol.76 (6), p.1273-1283
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A molecular basis for neurofibroma-associated skeletal manifestations in NF1
Author / Creator:Ma, Yun ; Gross, Andrea M. ; Dombi, Eva ; Pemov, Alexander ; Choi, Kwangmin ; Chaney, Katherine ; Rhodes, Steven D. ; Angus, Steven P. ; Sciaky, Noah ; Clapp, D. Wade ; Ratner, Nancy ; Widemann, Brigitte C. ; Rios, Jonathan J. ; Elefteriou, Florent
Publisher:New York: Nature Publishing Group US
Journal title:Genetics in medicine, 2020-11, Vol.22 (11), p.1786-1793
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Targeting Refractory Sarcomas and Malignant Peripheral Nerve Sheath Tumors in a Phase I/II Study of Sirolimus in Combination with Ganetespib (SARC023)
Author / Creator:De Raedt, Thomas ; Chawla, Sant ; Van Tine, Brian A. ; O’Sullivan, Geraldine ; Chen, Alice ; Cichowski, Karen ; Widemann, Brigitte C. ; Wolters, Pamela L. ; Basu, Mitali ; Perentesis, John ; Maertens, Ophélia ; Reinke, Denise ; Okuno, Scott H. ; Lu, Yao ; Kim, AeRang ; Chugh, Rashmi
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Complexity (New York, N.Y.), 2020, Vol.2020 (2020), p.1-8
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Showing 1 to 20 of 75 results

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Immune checkpoint inhibitors for refractory childhood cancers

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Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas

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Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study

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Selumetinib in Children with Inoperable Plexiform Neurofibromas

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Safety and efficacy of low-dose sirolimus in the PIK3CA-related overgrowth spectrum

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Longitudinal association between executive function and academic achievement in children with neurofibromatosis type 1 and plexiform neurofibromas

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Low-Intensity Therapy in Adults with Burkitt's Lymphoma

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

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Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial

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Outcome of Patients With Malignant Peripheral Nerve Sheath Tumors Enrolled on Sarcoma Alliance for Research Through Collaboration (SARC) Phase II Trials

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Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1

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The Landscape of US and Global Rare Tumor Research Programs: A Systematic Review

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Reporting of Racial and Ethnic Minority Representation in Early Phase Pediatric Oncology Clinical Trials

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Characterization of spinal findings in children and adults with neurofibromatosis type 1 enrolled in a natural history study using magnetic resonance imaging

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Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies

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A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

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Psychosocial Characteristics and Experiences in Patients with Multiple Endocrine Neoplasia Type 2 (MEN2) and Medullary Thyroid Carcinoma (MTC)

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Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory sol...

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A molecular basis for neurofibroma-associated skeletal manifestations in NF1

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Targeting Refractory Sarcomas and Malignant Peripheral Nerve Sheath Tumors in a Phase I/II Study of Sirolimus in Combination with Ganetespib (SARC023)

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