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72 results for X-Linked+Inhibitor+of+Apoptosis+Protein+-+antagonists+

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ArticlesPeer ReviewedFull Text
Fas death receptor signalling: roles of Bid and XIAP
Author / Creator:Kaufmann, T ; Strasser, A ; Jost, P J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2012-01, Vol.19 (1), p.42-50
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Targeting apoptosis in acute myeloid leukaemia
Author / Creator:Cassier, Philippe A ; Castets, Marie ; Belhabri, Amine ; Vey, Norbert
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2017-10, Vol.117 (8), p.1089-1098
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XIAP discriminates between type I and type II FAS-induced apoptosis
Author / Creator:Jost, Philipp J. ; Grabow, Stephanie ; Gray, Daniel ; McKenzie, Mark D. ; Nachbur, Ueli ; Huang, David C. S. ; Bouillet, Philippe ; Thomas, Helen E. ; Borner, Christoph ; Silke, John ; Strasser, Andreas ; Kaufmann, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-08, Vol.460 (7258), p.1035-1039
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DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death
Author / Creator:Thibault, Benoît ; Genre, Ludivine ; Le Naour, Augustin ; Broca, Clothilde ; Mery, Eliane ; Vuagniaux, Grégoire ; Delord, Jean Pierre ; Wiedemann, Norbert ; Couderc, Bettina
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-12, Vol.8 (1), p.17862-12, Article 17862
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Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response
Author / Creator:Zervantonakis, Ioannis K. ; Iavarone, Claudia ; Chen, Hsing-Yu ; Selfors, Laura M. ; Palakurthi, Sangeetha ; Liu, Joyce F. ; Drapkin, Ronny ; Matulonis, Ursula ; Leverson, Joel D. ; Sampath, Deepak ; Mills, Gordon B. ; Brugge, Joan S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-08, Vol.8 (1), p.365-13, Article 365
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Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs
Author / Creator:HUANG, YING ; YANG, XIANG ; XU, TIANRUI ; KONG, QINGHONG ; ZHANG, YAPING ; SHEN, YUEHAI ; WEI, YUNLIN ; WANG, GUANLIN ; CHANG, KWEN-JEN
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2016-07, Vol.49 (1), p.153-163
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The critical role of X-linked inhibitor of apoptosis protein (XIAP) in tumor development
Author / Creator:Fan, Hui ; Liu, Jiyuan ; Hu, Xiangyan ; Cai, Jiye ; Su, Bo ; Jiang, Jinhuan
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2025-06, Vol.30 (5), p.1202-1215
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Blocking XIAP:CASP7-p19 selectively induces apoptosis of CASP3/DR malignancies by a novel reversible small molecule
Author / Creator:Chen, Shih-Hsun ; Wu, Szu-Ying ; Chang, Yun-Xun ; Lui, En-Ning ; Chang, Chih-Kang ; Lin, Sheng-Wei ; Hsiao, Michael ; Yang, Jinn-Moon ; Liang, Po-Huang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-06, Vol.16 (1), p.459-13
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X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc)
Author / Creator:Bergmann, Christina ; Hallenberger, Ludwig ; Chenguiti Fakhouri, Sara ; Merlevede, Benita ; Brandt, Amelie ; Dees, Clara ; Zhu, Honglin ; Zehender, Ariella ; Zhou, Xiang ; Schwab, Annemarie ; Chen, Chih-Wei ; Györfi, Andrea Hermina ; Matei, Alexandru Emil ; Chakraborty, Debomita ; Trinh-Minh, Thuong ; Rauber, Simon ; Coras, Roland ; Bozec, Aline ; Kreuter, Alexander ; Ziemer, Mirjana ; Schett, Georg ; Distler, Jörg H W
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2021-08, Vol.80 (8), p.1048-1056
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inhibitors of apoptosis (IAPs) as cancer targets
Author / Creator:Hunter, Allison M ; LaCasse, Eric C ; Korneluk, Robert G
Publisher:Netherlands: New York : Kluwer Academic Publishers-Plenum Publishers
Journal title:Apoptosis (London), 2007-09, Vol.12 (9), p.1543-1568
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miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia
Author / Creator:Siegel, Chad ; Li, Jun ; Liu, Fudong ; Benashski, Sharon E ; McCullough, Louise D
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11662-11667
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A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity
Author / Creator:Ling, Xiang ; Cao, Shousong ; Cheng, Qiuying ; Keefe, James T. ; Rustum, Youcef M. ; Li, Fengzhi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e45571
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XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis
Author / Creator:Hussain, Azhar R. ; Siraj, Abdul Khalid ; Ahmed, Maqbool ; Bu, Rong ; Pratheeshkumar, Poyil ; Alrashed, Alanood M. ; Qadri, Zeeshan ; Ajarim, Dahish ; Al-Dayel, Fouad ; Beg, Shaham ; Al-Kuraya, Khawla S.
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2017-09, Vol.17 (1), p.640-640, Article 640
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Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism
Author / Creator:Allensworth, Jennifer L. ; Sauer, Scott J. ; Lyerly, H. Kim ; Morse, Michael A. ; Devi, Gayathri R.
Publisher:Boston: Springer US
Journal title:Breast cancer research and treatment, 2013-01, Vol.137 (2), p.359-371
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Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8
Author / Creator:Laussmann, M A ; Passante, E ; Düssmann, H ; Rauen, J A ; Würstle, M L ; Delgado, M E ; Devocelle, M ; Prehn, J H M ; Rehm, M
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2011-10, Vol.18 (10), p.1584-1597
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Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression
Author / Creator:Strekalova, Elena ; Malin, Dmitry ; Rajanala, Harisha ; Cryns, Vincent L.
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2017-06, Vol.163 (3), p.435-447
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Targeting XIAP for the treatment of malignancy
Author / Creator:Schimmer, A D ; Dalili, S ; Batey, R A ; Riedl, S J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2006-02, Vol.13 (2), p.179-188
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Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells
Author / Creator:Wang, Da-Guang ; Sun, Ya-Bin ; Ye, Fei ; Li, Wei ; Kharbuja, Punyaram ; Gao, Ling ; Zhang, David Y. ; Suo, Jian
Publisher:Boston: Springer US
Journal title:Molecular and cellular biochemistry, 2014-01, Vol.386 (1-2), p.143-152
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The XIAP inhibitor embelin sensitises malignant rhabdoid tumour cells to TRAIL treatment via enhanced activation of the extrinsic apoptotic pathway
Author / Creator:Coyle, Rachel ; Slattery, Karen ; Ennis, Leanne ; O'sullivan, Maureen ; Zisterer, Daniela
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2019-07, Vol.55 (1), p.191-202
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Cell-to-cell variability in inducible Caspase9-mediated cell death
Author / Creator:Yuan, Yuan ; Ren, Huixia ; Li, Yanjun ; Qin, Shanshan ; Yang, Xiaojing ; Tang, Chao
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2022-01, Vol.13 (1), p.34-34, Article 34
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Showing 1 to 20 of 72 results

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Fas death receptor signalling: roles of Bid and XIAP

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Targeting apoptosis in acute myeloid leukaemia

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XIAP discriminates between type I and type II FAS-induced apoptosis

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DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death

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Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

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Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs

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The critical role of X-linked inhibitor of apoptosis protein (XIAP) in tumor development

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Blocking XIAP:CASP7-p19 selectively induces apoptosis of CASP3/DR malignancies by a novel reversible small molecule

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X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc)

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inhibitors of apoptosis (IAPs) as cancer targets

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miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia

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A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

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XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis

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Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism

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Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8

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Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression

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Targeting XIAP for the treatment of malignancy

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Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells

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The XIAP inhibitor embelin sensitises malignant rhabdoid tumour cells to TRAIL treatment via enhanced activation of the extrinsic apoptotic pathway

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Cell-to-cell variability in inducible Caspase9-mediated cell death

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