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ArticlesPeer ReviewedFull Text
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
Author / Creator:Mount, Christopher W. ; Majzner, Robbie G. ; Sundaresh, Shree ; Arnold, Evan P. ; Kadapakkam, Meena ; Haile, Samuel ; Labanieh, Louai ; Hulleman, Esther ; Woo, Pamelyn J. ; Rietberg, Skyler P. ; Vogel, Hannes ; Monje, Michelle ; Mackall, Crystal L.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-05, Vol.24 (5), p.572-579
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The Antitumor Efficacy of β-Elemene by Changing Tumor Inflammatory Environment and Tumor Microenvironment
Author / Creator:Liu, Wenzhi ; Fang, Lei ; Li, Fengzhou ; Xie, Qiang ; Gu, Chundong
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2020, Vol.2020 (2020), p.1-13
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A second-generation M1-polarized CAR macrophage with antitumor efficacy
Author / Creator:Lei, Anhua ; Yu, Hua ; Lu, Shan ; Lu, Hengxing ; Ding, Xizhong ; Tan, Tianyu ; Zhang, Hailing ; Zhu, Mengmeng ; Tian, Lin ; Wang, Xudong ; Su, Siyu ; Xue, Dixuan ; Zhang, Shaolong ; Zhao, Wei ; Chen, Yuge ; Xie, Wanrun ; Zhang, Li ; Zhu, Yuqing ; Zhao, Jing ; Jiang, Wenhong ; Church, George ; Chan, Francis Ka-Ming ; Gao, Zhihua ; Zhang, Jin
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2024-01, Vol.25 (1), p.102-116
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CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
Author / Creator:Wang, Binglin ; Wang, Yi ; Sun, Xiaofan ; Deng, Guoliang ; Huang, Wei ; Wu, Xingxin ; Gu, Yanghong ; Tian, Zhigang ; Fan, Zhimin ; Xu, Qiang ; Chen, Hongqi ; Sun, Yang
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e003100
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CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors
Author / Creator:Jin, Linchun ; Tao, Haipeng ; Karachi, Aida ; Long, Yu ; Hou, Alicia Y. ; Na, Meng ; Dyson, Kyle A. ; Grippin, Adam J. ; Deleyrolle, Loic P. ; Zhang, Wang ; Rajon, Didier A. ; Wang, Qiong J. ; Yang, James C. ; Kresak, Jesse L. ; Sayour, Elias J. ; Rahman, Maryam ; Bova, Frank J. ; Lin, Zhiguo ; Mitchell, Duane A. ; Huang, Jianping
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4016-13, Article 4016
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ArticlesPeer ReviewedFull Text
Taurine enhances the antitumor efficacy of PD-1 antibody by boosting CD8+ T cell function
Author / Creator:Ping, Yu ; Shan, Jiqi ; Liu, Yaqing ; Liu, Fengsen ; Wang, Liuya ; Liu, Zhangnan ; Li, Jieyao ; Yue, Dongli ; Wang, Liping ; Chen, Xinfeng ; Zhang, Yi
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2023-04, Vol.72 (4), p.1015-1027
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Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models
Author / Creator:Schulte, Michael L ; Fu, Allie ; Zhao, Ping ; Li, Jun ; Geng, Ling ; Smith, Shannon T ; Kondo, Jumpei ; Coffey, Robert J ; Johnson, Marc O ; Rathmell, Jeffrey C ; Sharick, Joe T ; Skala, Melissa C ; Smith, Jarrod A ; Berlin, Jordan ; Washington, M Kay ; Nickels, Michael L ; Manning, H Charles
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-02, Vol.24 (2), p.194-202
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Pingyangmycin enhances the antitumor efficacy of anti-PD-1 therapy associated with tumor-infiltrating CD8+ T cell augmentation
Author / Creator:Shan, Chuan-Kun ; Du, Yi-Bo ; Zhai, Xiao-Tian ; Wang, Yue-Xuan ; Li, Yi ; Gong, Jian-Hua ; Ge, Zhi-Juan ; Liu, Xiu-Jun ; Zhen, Yong-Su
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2021-03, Vol.87 (3), p.425-436
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ArticlesPeer ReviewedFull Text
OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy
Author / Creator:Bulliard, Yannick ; Jolicoeur, Rose ; Zhang, Jimin ; Dranoff, Glenn ; Wilson, Nicholas S ; Brogdon, Jennifer L
Publisher:United States: Nature Publishing Group
Journal title:Immunology and cell biology, 2014-07, Vol.92 (6), p.475-480
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ArticlesPeer ReviewedFull Text
Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
Author / Creator:Zhang, Hongxia ; You, Xinru ; Wang, Xiaojuan ; Cui, Lei ; Wang, Zining ; Feifei Xua, Mengyun Li ; Yang, Zhenggang ; Liu, Jinyun ; Huang, Peng ; Kang, Yang ; Wu, Jun ; Xia, Xiaojun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (6), p.1-12
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ArticlesPeer ReviewedFull Text
Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment
Author / Creator:Yeku, Oladapo O. ; Purdon, Terence J. ; Koneru, Mythili ; Spriggs, David ; Brentjens, Renier J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-09, Vol.7 (1), p.10541, Article 10541
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ArticlesPeer ReviewedFull Text
Decitabine priming increases anti–PD-1 antitumor efficacy by promoting CD8+ progenitor exhausted T cell expansion in tumor models
Author / Creator:Li, Xiang ; Li, Yaru ; Dong, Liang ; Chang, Yixin ; Zhang, Xingying ; Wang, Chunmeng ; Chen, Meixia ; Bo, Xiaochen ; Chen, Hebing ; Han, Weidong ; Nie, Jing
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-04, Vol.133 (7), p.1-17
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Improving antitumor efficacy via combinatorial regimens of oncolytic virotherapy
Author / Creator:Zhang, Bin ; Cheng, Ping
Publisher:London: BioMed Central Ltd
Journal title:Molecular cancer, 2020-11, Vol.19 (1), p.1-158, Article 158
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The novel and potent CD40 agonist KHK2840 augments the antitumor efficacy of anti‐PD‐1 antibody and paclitaxel
Author / Creator:Kobayashi, Chiaki ; Suzuki‐Imaizumi, Minami ; Sakaguchi, Yasuko ; Ishii, Toshihiko ; Adachi, Maiko ; Kaneda, Ayumi ; Ebihara, Ritsuko ; Saito, Masato ; Uemori, Takeshi ; Mori, Kiyotoshi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2024-12, Vol.115 (12), p.4008-4020
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A novel enediyne‐integrated antibody–drug conjugate shows promising antitumor efficacy against CD30+ lymphomas
Author / Creator:Wang, Rong ; Li, Liang ; Zhang, Shenghua ; Li, Yi ; Wang, Xiaofei ; Miao, Qingfang ; Zhen, Yongsu
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2018-03, Vol.12 (3), p.339-355
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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
Author / Creator:Gattinoni, L.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2005-06, Vol.115 (6), p.1616-1626
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Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity
Author / Creator:Pai, Chien-Chun Steven ; Simons, Donald M. ; Lu, Xiaoqing ; Evans, Michael ; Wei, Junnian ; Wang, Yung-hua ; Chen, Mingyi ; Huang, John ; Park, Chanhyuk ; Chang, Anthony ; Wang, Jiaxi ; Westmoreland, Susan ; Beam, Christine ; Banach, Dave ; Bowley, Diana ; Dong, Feng ; Seagal, Jane ; Ritacco, Wendy ; Richardson, Paul L. ; Mitra, Soumya ; Lynch, Grace ; Bousquet, Pete ; Mankovich, John ; Kingsbury, Gillian ; Fong, Lawrence
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-01, Vol.129 (1), p.349-363
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Antibody‐drug conjugate MORAb‐202 exhibits long‐lasting antitumor efficacy in TNBC PDx models
Author / Creator:Furuuchi, Keiji ; Rybinski, Katherine ; Fulmer, James ; Moriyama, Tomoyuki ; Drozdowski, Brian ; Soto, Allis ; Fernando, Shawn ; Wilson, Kerrianne ; Milinichik, Andrew ; Dula, Mary Lou ; Tanaka, Keigo ; Cheng, Xin ; Albone, Earl ; Uenaka, Toshimitsu
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2021-06, Vol.112 (6), p.2467-2480
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ArticlesPeer ReviewedFull Text
Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade
Author / Creator:Qin, Ye ; Vasilatos, Shauna N. ; Chen, Lin ; Wu, Hao ; Cao, Zhishen ; Fu, Yumei ; Huang, Min ; Vlad, Anda M. ; Lu, Binfeng ; Oesterreich, Steffi ; Davidson, Nancy E. ; Huang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2019-01, Vol.38 (3), p.390-405
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Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression
Author / Creator:Curran, Kevin J ; Seinstra, Beatrijs A ; Nikhamin, Yan ; Yeh, Raymond ; Usachenko, Yelena ; van Leeuwen, Dayenne G ; Purdon, Terence ; Pegram, Hollie J ; Brentjens, Renier J
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2015-04, Vol.23 (4), p.769-778
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Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas

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The Antitumor Efficacy of β-Elemene by Changing Tumor Inflammatory Environment and Tumor Microenvironment

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A second-generation M1-polarized CAR macrophage with antitumor efficacy

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CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell

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CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors

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Taurine enhances the antitumor efficacy of PD-1 antibody by boosting CD8+ T cell function

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Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

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Pingyangmycin enhances the antitumor efficacy of anti-PD-1 therapy associated with tumor-infiltrating CD8+ T cell augmentation

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OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy

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Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling

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Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment

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Decitabine priming increases anti–PD-1 antitumor efficacy by promoting CD8+ progenitor exhausted T cell expansion in tumor models

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Improving antitumor efficacy via combinatorial regimens of oncolytic virotherapy

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The novel and potent CD40 agonist KHK2840 augments the antitumor efficacy of anti‐PD‐1 antibody and paclitaxel

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A novel enediyne‐integrated antibody–drug conjugate shows promising antitumor efficacy against CD30+ lymphomas

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

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Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity

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Antibody‐drug conjugate MORAb‐202 exhibits long‐lasting antitumor efficacy in TNBC PDx models

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Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade

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Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression

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