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Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice
Author / Creator:Masters, Elysia A ; de Mesy Bentley, Karen L ; Gill, Ann Lindley ; Hao, Stephanie P ; Galloway, Chad A ; Salminen, Alec T ; Guy, Diamond R ; McGrath, James L ; Awad, Hani A ; Gill, Steven R ; Schwarz, Edward M
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-10, Vol.16 (10), p.e1008988
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The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
Author / Creator:Lee, Hakjoo ; Lee, Tae Jin ; Galloway, Chad A. ; Zhi, Wenbo ; Xiao, Wei ; de Mesy Bentley, Karen L. ; Sharma, Ashok ; Teng, Yong ; Sesaki, Hiromi ; Yoon, Yisang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6721-6721, Article 6721
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Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associat...
Author / Creator:Trombetta, Ryan P ; Ninomiya, Mark J ; El-Atawneh, Ihab M ; Knapp, Emma K ; de Mesy Bentley, Karen L ; Dunman, Paul M ; Schwarz, Edward M ; Kates, Stephen L ; Awad, Hani A
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2019-02, Vol.11 (2), p.94
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Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"
Author / Creator:Masters, Elysia A ; Trombetta, Ryan P ; de Mesy Bentley, Karen L ; Boyce, Brendan F ; Gill, Ann Lindley ; Gill, Steven R ; Nishitani, Kohei ; Ishikawa, Masahiro ; Morita, Yugo ; Ito, Hiromu ; Bello-Irizarry, Sheila N ; Ninomiya, Mark ; Brodell, Jr, James D ; Lee, Charles C ; Hao, Stephanie P ; Oh, Irvin ; Xie, Chao ; Awad, Hani A ; Daiss, John L ; Owen, John R ; Kates, Stephen L ; Schwarz, Edward M ; Muthukrishnan, Gowrishankar
Publisher:China: Springer Nature B.V
Journal title:Bone research, 2019-07, Vol.7, p.20-18
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Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice
Author / Creator:Halim, Danny ; Wilson, Michael P. ; Oliver, Daniel ; Brosens, Erwin ; Verheij, Joke B. G. M. ; Han, Yu ; Nanda, Vivek ; Lyu, Qing ; Doukas, Michael ; Stoop, Hans ; Brouwer, Rutger W. W. ; van IJcken, Wilfred F. J. ; Slivano, Orazio J. ; Burns, Alan J. ; Christie, Christine K. ; de Mesy Bentley, Karen L. ; Brooks, Alice S. ; Tibboel, Dick ; Xu, Suowen ; Jin, Zheng Gen ; Djuwantono, Tono ; Yan, Wei ; Alves, Maria M. ; Hofstra, Robert M. W. ; Miano, Joseph M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (13), p.E2738-E2747
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Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis
Author / Creator:Ren, Youliang ; Weeks, Jason ; Xue, Thomas ; Rainbolt, Joshua ; de Mesy Bentley, Karen L ; Shu, Ye ; Liu, Yuting ; Masters, Elysia ; Cherian, Philip ; McKenna, Charles E ; Neighbors, Jeffrey ; Ebetino, Frank H ; Schwarz, Edward M ; Sun, Shuting ; Xie, Chao
Publisher:China: Springer Nature B.V
Journal title:Bone research, 2023-10, Vol.11 (1), p.51
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Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis
Author / Creator:Bouta, Echoe M ; Ju, Yawen ; Rahimi, Homaira ; de Mesy-Bentley, Karen L ; Wood, Ronald W ; Xing, Lianping ; Schwarz, Edward M
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e73766-e73766
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ArticlesPeer ReviewedFull Text
HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization
Author / Creator:Norman, John P ; Perry, Seth W ; Reynolds, Holly M ; Kiebala, Michelle ; De Mesy Bentley, Karen L ; Trejo, Margarita ; Volsky, David J ; Maggirwar, Sanjay B ; Dewhurst, Stephen ; Masliah, Eliezer ; Gelbard, Harris A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-11, Vol.3 (11), p.e3731
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Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid
Author / Creator:Adjei-Sowah, Emmanuela ; Peng, Yue ; Weeks, Jason ; Jonason, Jennifer ; de Mesy Bentley, Karen ; Masters, Elysia ; Morita, Yugo ; Muthukrishnan, Gowrishankar ; Cherian, Philip ; Hu, X. ; McKenna, Charles ; Ebetino, Frank ; Sun, Shuting ; Schwarz, Edward ; Xie, Chao
Publisher:Basel: MDPI AG
Journal title:Antibiotics (Basel), 2021-06, Vol.10 (6), p.732
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ArticlesPeer ReviewedFull Text
Restricted Inactivation of Serum Response Factor to the Cardiovascular System
Author / Creator:Miano, Joseph M. ; Ramanan, Narendrakumar ; Georger, Mary A. ; Karen L. de Mesy Bentley ; Emerson, Rachael L. ; Balza, Robert O. ; Xiao, Qi ; Weiler, Hartmut ; Ginty, David D. ; Misra, Ravi P. ; Olson, Eric N.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-12, Vol.101 (49), p.17132-17137
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ArticlesPeer ReviewedFull Text
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
Author / Creator:Rappold, Phillip M. ; Cui, Mei ; Grima, Jonathan C. ; Fan, Rebecca Z. ; de Mesy-Bentley, Karen L. ; Chen, Linan ; Zhuang, Xiaoxi ; Bowers, William J. ; Tieu, Kim
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-11, Vol.5 (1), p.5244, Article 5244
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ArticlesPeer ReviewedFull Text
Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease
Author / Creator:Mestre, Humberto ; Verma, Natasha ; Greene, Thom D. ; Lin, LiJing A. ; Ladron-de-Guevara, Antonio ; Sweeney, Amanda M. ; Liu, Guojun ; Thomas, V. Kaye ; Galloway, Chad A. ; de Mesy Bentley, Karen L. ; Nedergaard, Maiken ; Mehta, Rupal I.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.3897-3897, Article 3897
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ArticlesPeer ReviewedFull Text
The complex genetics of hypoplastic left heart syndrome
Author / Creator:Liu, Xiaoqin ; Yagi, Hisato ; Saeed, Shazina ; Bais, Abha S ; Gabriel, George C ; Chen, Zhaohan ; Peterson, Kevin A ; Li, You ; Schwartz, Molly C ; Reynolds, William T ; Saydmohammed, Manush ; Gibbs, Brian ; Wu, Yijen ; Devine, William ; Chatterjee, Bishwanath ; Klena, Nikolai T ; Kostka, Dennis ; de Mesy Bentley, Karen L ; Ganapathiraju, Madhavi K ; Dexheimer, Phillip ; Leatherbury, Linda ; Khalifa, Omar ; Bhagat, Anchit ; Zahid, Maliha ; Pu, William ; Watkins, Simon ; Grossfeld, Paul ; Murray, Stephen A ; Porter, George A ; Tsang, Michael ; Martin, Lisa J ; Benson, D Woodrow ; Aronow, Bruce J ; Lo, Cecilia W
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-07, Vol.49 (7), p.1152-1159
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ArticlesPeer ReviewedFull Text
Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone
Author / Creator:Shum, Laura C ; White, Noelle S ; Nadtochiy, Sergiy M ; Bentley, Karen L de Mesy ; Brookes, Paul S ; Jonason, Jennifer H ; Eliseev, Roman A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-05, Vol.11 (5), p.e0155709-e0155709
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Cutaneous Superficial Basal Cell Carcinoma is a Basal Cell Carcinoma In Situ: Electron Microscopy of a Case Series of Basal Cell Carcinomas
Author / Creator:Kaur, Harsimran ; de Mesy Bentley, Karen L. ; Rahman, Syed Minhaj ; Cohen, Philip R. ; Smoller, Bruce R.
Publisher:Cheshire: Springer Healthcare
Journal title:Dermatology and therapy, 2024-05, Vol.14 (5), p.1359-1366
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ArticlesPeer ReviewedFull Text
Skeletal infections: microbial pathogenesis, immunity and clinical management
Author / Creator:Masters, Elysia A. ; Ricciardi, Benjamin F. ; Bentley, Karen L. de Mesy ; Moriarty, T. Fintan ; Schwarz, Edward M. ; Muthukrishnan, Gowrishankar
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2022-07, Vol.20 (7), p.385-400
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ArticlesPeer ReviewedFull Text
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation
Author / Creator:Morita, Yugo ; Saito, Motoo ; Rangel-Moreno, Javier ; Franchini, Anthony M ; Owen, John R ; Martinez, John C ; Daiss, John L ; de Mesy Bentley, Karen L ; Kates, Stephen L ; Schwarz, Edward M ; Muthukrishnan, Gowrishankar
Publisher:China: Springer Nature B.V
Journal title:Bone research, 2022-08, Vol.10 (1), p.56
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ArticlesPeer ReviewedFull Text
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells
Author / Creator:Yee, Min ; Domm, William ; Gelein, Robert ; Bentley, Karen L de Mesy ; Kottmann, R Matthew ; Sime, Patricia J ; Lawrence, B Paige ; O'Reilly, Michael A
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2017-04, Vol.56 (4), p.453-464
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ArticlesPeer ReviewedFull Text
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells
Author / Creator:Yee, Min ; Domm, William ; Gelein, Robert ; Bentley, Karen L. de Mesy ; Kottmann, R. Matthew ; Sime, Patricia J. ; Lawrence, B. Paige ; O’Reilly, Michael A.
Journal title:American journal of respiratory cell and molecular biology, 2017-04, Vol.56 (4), p.453-464
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ArticlesPeer ReviewedFull Text
Identification of Penicillin Binding Protein 4
Author / Creator:Masters, Elysia A ; de Mesy Bentley, Karen L ; Gill, Ann Lindley ; Hao, Stephanie P ; Galloway, Chad A ; Salminen, Alec T ; Guy, Diamond R ; McGrath, James L ; Awad, Hani A ; Gill, Steven R ; Schwarz, Edward M
Publisher:Public Library of Science
Journal title:PLoS pathogens, 2020-10, Vol.16 (10)
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Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice

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The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury

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Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associat...

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Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"

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Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice

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Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis

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Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis

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HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization

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Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid

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Restricted Inactivation of Serum Response Factor to the Cardiovascular System

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Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo

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Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease

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The complex genetics of hypoplastic left heart syndrome

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Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone

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Cutaneous Superficial Basal Cell Carcinoma is a Basal Cell Carcinoma In Situ: Electron Microscopy of a Case Series of Basal Cell Carcinomas

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Skeletal infections: microbial pathogenesis, immunity and clinical management

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Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation

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Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells

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Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells

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Identification of Penicillin Binding Protein 4

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