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ArticlesPeer ReviewedFull Text
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity
Author / Creator:Kaptein, Suzanne J. F. ; Jacobs, Sofie ; Langendries, Lana ; Seldeslachts, Laura ; ter Horst, Sebastiaan ; Liesenborghs, Laurens ; Hens, Bart ; Vergote, Valentijn ; Heylen, Elisabeth ; Barthelemy, Karine ; Maas, Elke ; De Keyzer, Carolien ; Bervoets, Lindsey ; Rymenants, Jasper ; Van Buyten, Tina ; Zhang, Xin ; Abdelnabi, Rana ; Pang, Juanita ; Williams, Rachel ; Thibaut, Hendrik Jan ; Dallmeier, Kai ; Boudewijns, Robbert ; Wouters, Jens ; Augustijns, Patrick ; Verougstraete, Nick ; Cawthorne, Christopher ; Breuer, Judith ; Solas, Caroline ; Weynand, Birgit ; Annaert, Pieter ; Spriet, Isabel ; Velde, Greetje Vande ; Neyts, Johan ; Rocha-Pereira, Joana ; Delang, Leen
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (43), p.26955-26965
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Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase
Author / Creator:FURUTA, Yousuke ; KOMENO, Takashi ; NAKAMURA, Takaaki
Publisher:Japan: The Japan Academy
Journal title:Proceedings of the Japan Academy, Series B, 2017/08/02, Vol.93(7), pp.449-463
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Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea
Author / Creator:Sissoko, Daouda ; Laouenan, Cedric ; Folkesson, Elin ; M’Lebing, Abdoul-Bing ; Beavogui, Abdoul-Habib ; Baize, Sylvain ; Camara, Alseny-Modet ; Maes, Piet ; Shepherd, Susan ; Danel, Christine ; Carazo, Sara ; Conde, Mamoudou N. ; Gala, Jean-Luc ; Colin, Géraldine ; Savini, Hélène ; Bore, Joseph Akoi ; Le Marcis, Frederic ; Koundouno, Fara Raymond ; Petitjean, Frédéric ; Lamah, Marie-Claire ; Diederich, Sandra ; Tounkara, Alexis ; Poelart, Geertrui ; Berbain, Emmanuel ; Dindart, Jean-Michel ; Duraffour, Sophie ; Lefevre, Annabelle ; Leno, Tamba ; Peyrouset, Olivier ; Irenge, Léonid ; Bangoura, N’Famara ; Palich, Romain ; Hinzmann, Julia ; Kraus, Annette ; Barry, Thierno Sadou ; Berette, Sakoba ; Bongono, André ; Camara, Mohamed Seto ; Chanfreau Munoz, Valérie ; Doumbouya, Lanciné ; Souley Harouna ; Kighoma, Patient Mumbere ; Koundouno, Fara Roger ; Réné Lolamou ; Loua, Cécé Moriba ; Massala, Vincent ; Moumouni, Kinda ; Provost, Célia ; Samake, Nenefing ; Sekou, Conde ; Soumah, Abdoulaye ; Arnould, Isabelle ; Komano, Michel Saa ; Gustin, Lina ; Berutto, Carlotta ; Camara, Diarra ; Camara, Fodé Saydou ; Colpaert, Joliene ; Delamou, Léontine ; Jansson, Lena ; Kourouma, Etienne ; Loua, Maurice ; Malme, Kristian ; Manfrin, Emma ; Maomou, André ; Milinouno, Adele ; Ombelet, Sien ; Sidiboun, Aboubacar Youla ; Verreckt, Isabelle ; Yombouno, Pauline ; Bocquin, Anne ; Carbonnelle, Caroline ; Carmoi, Thierry ; Frange, Pierre ; Mely, Stéphane ; Nguyen, Vinh-Kim ; Pannetier, Delphine ; Taburet, Anne-Marie ; Treluyer, Jean-Marc ; Kolie, Jacques ; Moh, Raoul ; Gonzalez, Minerva Cervantes ; Kuisma, Eeva ; Liedigk, Britta ; Ngabo, Didier ; Rudolf, Martin ; Thom, Ruth ; Kerber, Romy ; Gabriel, Martin ; Di Caro, Antonino ; Wölfel, Roman ; Badir, Jamal ; Bentahir, Mostafa ; Deccache, Yann ; Dumont, Catherine ; Durant, Jean-François ; El Bakkouri, Karim ; Gasasira Uwamahoro, Marie ; Smits, Benjamin ; Toufik, Nora
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2016-03, Vol.13 (3), p.e1001967-e1001967
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ArticlesPeer ReviewedFull Text
The mechanism of resistance to favipiravir in influenza
Author / Creator:Goldhill, Daniel H. ; te Velthuis, Aartjan J. W. ; Fletcher, Robert A. ; Langat, Pinky ; Zambon, Maria ; Lackenby, Angie ; Barclay, Wendy S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11613-11618
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Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)—Sierra Leone, 2014
Author / Creator:Bai, Chang-Qing ; Mu, Jin-Song ; Kargbo, David ; Song, Ya-Bin ; Niu, Wen-Kai ; Nie, Wei-Min ; Kanu, Alex ; Liu, Wei-Wei ; Wang, Yao-Ping ; Dafae, Foday ; Yan, Tao ; Hu, Yi ; Deng, Yong-Qiang ; Lu, Hui-Jun ; Yang, Fan ; Zhang, Xiao-Guang ; Sun, Yang ; Cao, Yu-Xi ; Su, Hao-Xiang ; Sun, Yu ; Liu, Wen-Sen ; Wang, Cheng-Yu ; Qian, Jun ; Liu, Liu ; Wang, Hong ; Tong, Yi-Gang ; Liu, Ze-Yuan ; Chen, Yun-Song ; Wang, Hong-Quan ; Kargbo, Brima ; Gao, George F. ; Jiang, Jia-Fu
Publisher:United States: Oxford University Press
Journal title:Clinical infectious diseases, 2016-11, Vol.63 (10), p.1288-1294
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ArticlesPeer ReviewedFull Text
Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model
Author / Creator:Driouich, Jean-Sélim ; Cochin, Maxime ; Lingas, Guillaume ; Moureau, Grégory ; Touret, Franck ; Petit, Paul-Rémi ; Piorkowski, Géraldine ; Barthélémy, Karine ; Laprie, Caroline ; Coutard, Bruno ; Guedj, Jérémie ; de Lamballerie, Xavier ; Solas, Caroline ; Nougairède, Antoine
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1735-13, Article 1735
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The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase
Author / Creator:Jin, Zhinan ; Smith, Lucas K. ; Rajwanshi, Vivek K. ; Kim, Baek ; Deval, Jerome
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e68347
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Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study
Author / Creator:Dabbous, Hany M ; Abd-Elsalam, Sherief ; El-Sayed, Manal H ; Sherief, Ahmed F ; Ebeid, Fatma F S ; El Ghafar, Mohamed Samir Abd ; Soliman, Shaimaa ; Elbahnasawy, Mohamed ; Badawi, Rehab ; Tageldin, Mohamed Awad
Publisher:Austria: Springer Vienna
Journal title:Archives of virology, 2021-03, Vol.166 (3), p.949-954
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Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
Author / Creator:Naydenova, Katerina ; Muir, Kyle W. ; Wu, Long-Fei ; Zhang, Ziguo ; Coscia, Francesca ; Peet, Mathew J. ; Castro-Hartmann, Pablo ; Qian, Pu ; Sader, Kasim ; Dent, Kyle ; Kimanius, Dari ; Sutherland, John D. ; Löwe, Jan ; Barford, David ; Russo, Christopher J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (7), p.1-6
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Use of Favipiravir to Treat Lassa Virus Infection in Macaques
Author / Creator:Rosenke, Kyle ; Feldmann, Heinz ; Westover, Jonna B. ; Hanley, Patrick William ; Martellaro, Cynthia ; Feldmann, Friederike ; Saturday, Greg ; Lovaglio, Jamie ; Scott, Dana P. ; Furuta, Yousuke ; Komeno, Takashi ; Gowen, Brian B. ; Safronetz, David
Publisher:United States: U.S. National Center for Infectious Diseases
Journal title:Emerging infectious diseases, 2018-09, Vol.24 (9), p.1696-1699
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Effectiveness of favipiravir in COVID-19: a live systematic review
Author / Creator:Özlüşen, Batu ; Kozan, Şima ; Akcan, Rüştü Emre ; Kalender, Mekselina ; Yaprak, Doğukan ; Peltek, İbrahim Batuhan ; Keske, Şiran ; Gönen, Mehmet ; Ergönül, Önder
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of clinical microbiology & infectious diseases, 2021-12, Vol.40 (12), p.2575-2583
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HPLC-UV method for quantification of favipiravir in pharmaceutical formulations
Author / Creator:Bulduk, İbrahim
Publisher:Budapest: Akademiai Kiado Zrt
Journal title:Acta chromatographica, 2021-09, Vol.33 (3), p.209-215
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Favipiravir for the treatment of patients with COVID-19: a systematic review and meta-analysis
Author / Creator:Manabe, Toshie ; Kambayashi, Dan ; Akatsu, Hiroyasu ; Kudo, Koichiro
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2021-05, Vol.21 (1), p.489-13, Article 489
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Pharmacokinetics of Favipiravir in Critically Ill Patients With COVID‐19
Author / Creator:Irie, Kei ; Nakagawa, Atsushi ; Fujita, Hirotoshi ; Tamura, Ryo ; Eto, Masaaki ; Ikesue, Hiroaki ; Muroi, Nobuyuki ; Tomii, Keisuke ; Hashida, Tohru
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2020-09, Vol.13 (5), p.880-885
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Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series
Author / Creator:Doi, Kent ; Ikeda, Mahoko ; Hayase, Naoki ; Moriya, Kyoji ; Morimura, Naoto ; Maehara, Hiromu ; Tagami, Shunsuke ; Fukushima, Kazutaka ; Misawa, Naho ; Inoue, Yutaro ; Nakamura, Hitomi ; Takai, Daisuke ; Kurimoto, Mio ; Tokunaga, Kurato ; Yamamoto, Miyuki ; Hirayama, Ichiro ; Horie, Ryohei ; Endo, Yuri ; Hiwatashi, Kengo ; Shikama, Mio ; Jubishi, Daisuke ; Kanno, Yoshiaki ; Okamoto, Koh ; Harada, Sohei ; Okugawa, Shu ; Miyazono, Kohei ; Seto, Yasuyuki ; Inoue, Jun-ichiro
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2020-07, Vol.24 (1), p.392-392, Article 392
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Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
Author / Creator:Shannon, Ashleigh ; Selisko, Barbara ; Le, Nhung-Thi-Tuyet ; Huchting, Johanna ; Touret, Franck ; Piorkowski, Géraldine ; Fattorini, Véronique ; Ferron, François ; Decroly, Etienne ; Meier, Chris ; Coutard, Bruno ; Peersen, Olve ; Canard, Bruno
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.1-9, Article 4682
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Combination of (interferon beta-1b, lopinavir/ritonavir and ribavirin) versus favipiravir in hospitalized patients with non-critical COVID-19: A cohort study
Author / Creator:A. Malhani, Areej ; A. Enani, Mushira ; Saheb Sharif-Askari, Fatemeh ; R. Alghareeb, Mona ; T. Bin-Brikan, Roaa ; A. AlShahrani, Safar ; Halwani, Rabih ; Tleyjeh, Imad M.
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2021-06, Vol.16 (6), p.e0252984-e0252984
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The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials
Author / Creator:Hassanipour, Soheil ; Arab-Zozani, Morteza ; Amani, Bahman ; Heidarzad, Forough ; Fathalipour, Mohammad ; Martinez-de-Hoyo, Rudolph
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.11022-11, Article 11022
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Favipiravir: Erythema and transaminase elevation: case report
Publisher:Cham: Springer International Publishing
Journal title:Reactions weekly, 2022-06, Vol.1910 (1), p.215-215
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Favipiravir: Various toxicities: 3 case reports
Publisher:Cham: Springer International Publishing
Journal title:Reactions weekly, 2022-06, Vol.1910 (1), p.216-216
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Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity

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Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

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Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

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The mechanism of resistance to favipiravir in influenza

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Clinical and Virological Characteristics of Ebola Virus Disease Patients Treated With Favipiravir (T-705)—Sierra Leone, 2014

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Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model

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The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

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Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

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Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP

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Use of Favipiravir to Treat Lassa Virus Infection in Macaques

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Effectiveness of favipiravir in COVID-19: a live systematic review

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HPLC-UV method for quantification of favipiravir in pharmaceutical formulations

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Favipiravir for the treatment of patients with COVID-19: a systematic review and meta-analysis

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Pharmacokinetics of Favipiravir in Critically Ill Patients With COVID‐19

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Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series

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Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

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Combination of (interferon beta-1b, lopinavir/ritonavir and ribavirin) versus favipiravir in hospitalized patients with non-critical COVID-19: A cohort study

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The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials

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Favipiravir: Erythema and transaminase elevation: case report

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Favipiravir: Various toxicities: 3 case reports

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