Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phe...
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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It has been hypothesized that α-synuclein (αS) misfolding may begin in peripheral nerves and spread to the central nervous system (CNS), leading to Parkinson disease and related disorders. Although recent data suggest that αS pathology can spread within the mouse brain, there is no direct evidence for spread of disease from a peripheral site. In th...
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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
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TN_cdi_crossref_primary_10_1073_pnas_1321785111
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1321785111
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1321785111
