Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA...
Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data
About this item
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Author / Creator
Camacho, Niedzica , Van Loo, Peter , Edwards, Sandra , Kay, Jonathan D , Matthews, Lucy , Haase, Kerstin , Clark, Jeremy , Dennis, Nening , Thomas, Sarah , Kremeyer, Barbara , Zamora, Jorge , Butler, Adam P , Gundem, Gunes , Merson, Sue , Luxton, Hayley , Hawkins, Steve , Ghori, Mohammed , Marsden, Luke , Lambert, Adam , Karaszi, Katalin , Pelvender, Gill , Massie, Charlie E , Kote-Jarai, Zsofia , Raine, Keiran , Jones, David , Howat, William J , Hazell, Steven , Livni, Naomi , Fisher, Cyril , Ogden, Christopher , Kumar, Pardeep , Thompson, Alan , Nicol, David , Mayer, Erik , Dudderidge, Tim , Yu, Yongwei , Zhang, Hongwei , Shah, Nimish C , Gnanapragasam, Vincent J , Isaacs, William , Visakorpi, Tapio , Hamdy, Freddie , Berney, Dan , Verrill, Clare , Warren, Anne Y , Wedge, David C , Lynch, Andrew G , Foster, Christopher S , Lu, Yong Jie , Bova, G Steven , Whitaker, Hayley C , McDermott, Ultan , Neal, David E , Eeles, Rosalind , Cooper, Colin S , Brewer, Daniel S , CRUK-ICGC Prostate Group and The CRUK-ICGC Prostate Group
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
A variety of models have been proposed to explain regions of recurrent somatic copy number alteration (SCNA) in human cancer. Our study employs Whole Genome DNA Sequence (WGS) data from tumor samples (n = 103) to comprehensively assess the role of the Knudson two hit genetic model in SCNA generation in prostate cancer. 64 recurrent regions of loss...
Alternative Titles
Full title
Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data
Authors, Artists and Contributors
Author / Creator
Van Loo, Peter
Edwards, Sandra
Kay, Jonathan D
Matthews, Lucy
Haase, Kerstin
Clark, Jeremy
Dennis, Nening
Thomas, Sarah
Kremeyer, Barbara
Zamora, Jorge
Butler, Adam P
Gundem, Gunes
Merson, Sue
Luxton, Hayley
Hawkins, Steve
Ghori, Mohammed
Marsden, Luke
Lambert, Adam
Karaszi, Katalin
Pelvender, Gill
Massie, Charlie E
Kote-Jarai, Zsofia
Raine, Keiran
Jones, David
Howat, William J
Hazell, Steven
Livni, Naomi
Fisher, Cyril
Ogden, Christopher
Kumar, Pardeep
Thompson, Alan
Nicol, David
Mayer, Erik
Dudderidge, Tim
Yu, Yongwei
Zhang, Hongwei
Shah, Nimish C
Gnanapragasam, Vincent J
Isaacs, William
Visakorpi, Tapio
Hamdy, Freddie
Berney, Dan
Verrill, Clare
Warren, Anne Y
Wedge, David C
Lynch, Andrew G
Foster, Christopher S
Lu, Yong Jie
Bova, G Steven
Whitaker, Hayley C
McDermott, Ultan
Neal, David E
Eeles, Rosalind
Cooper, Colin S
Brewer, Daniel S
CRUK-ICGC Prostate Group
The CRUK-ICGC Prostate Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1951453459
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1951453459
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007001
