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The evolutionary history of lethal metastatic prostate cancer
Author / Creator:Gundem, Gunes ; Van Loo, Peter ; Kremeyer, Barbara ; Alexandrov, Ludmil B. ; Tubio, Jose M. C. ; Papaemmanuil, Elli ; Brewer, Daniel S. ; Kallio, Heini M. L. ; Högnäs, Gunilla ; Annala, Matti ; Kivinummi, Kati ; Goody, Victoria ; Latimer, Calli ; O'Meara, Sarah ; Dawson, Kevin J. ; Isaacs, William ; Emmert-Buck, Michael R. ; Nykter, Matti ; Foster, Christopher ; Kote-Jarai, Zsofia ; Easton, Douglas ; Whitaker, Hayley C. ; Neal, David E. ; Cooper, Colin S. ; Eeles, Rosalind A. ; Visakorpi, Tapio ; Campbell, Peter J. ; McDermott, Ultan ; Wedge, David C. ; Bova, G. Steven
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-04, Vol.520 (7547), p.353-357
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Joint estimation of relaxation and diffusion tissue parameters for prostate cancer with relaxation-VERDICT MRI
Author / Creator:Palombo, Marco ; Valindria, Vanya ; Singh, Saurabh ; Chiou, Eleni ; Giganti, Francesco ; Pye, Hayley ; Whitaker, Hayley C. ; Atkinson, David ; Punwani, Shonit ; Alexander, Daniel C. ; Panagiotaki, Eleftheria
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-02, Vol.13 (1), p.2999-2999, Article 2999
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Use of artificial intelligence in the detection of primary prostate cancer in multiparametric MRI with its clinical outcomes: a protocol for a systematic review and meta-analysis
Author / Creator:Thomas, Maya ; Murali, Sanjana ; Simpson, Benjamin Scott S ; Freeman, Alex ; Kirkham, Alex ; Kelly, Daniel ; Whitaker, Hayley C ; Zhao, Yi ; Emberton, Mark ; Norris, Joseph M
Publisher:London: British Medical Journal Publishing Group
Journal title:BMJ open, 2023-08, Vol.13 (8), p.e074009-e074009
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The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates
Author / Creator:Buhigas, Claudia ; Warren, Anne Y ; Leung, Wing-Kit ; Whitaker, Hayley C ; Luxton, Hayley J ; Hawkins, Steve ; Kay, Jonathan ; Butler, Adam ; Xu, Yaobo ; Woodcock, Dan J ; Merson, Sue ; Frame, Fiona M ; Sahli, Atef ; Abascal, Federico ; Martincorena, Iñigo ; Bova, G Steven ; Foster, Christopher S ; Campbell, Peter ; Maitland, Norman J ; Neal, David E ; Massie, Charlie E ; Lynch, Andy G ; Eeles, Rosalind A ; Cooper, Colin S ; Wedge, David C ; Brewer, Daniel S
Publisher:England: BioMed Central
Journal title:Molecular cancer, 2022-09, Vol.21 (1), p.183-183, Article 183
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Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer
Author / Creator:Luszczak, Sabina ; Simpson, Benjamin S. ; Stopka-Farooqui, Urszula ; Sathyadevan, Vignesh Krishna ; Echeverria, Lina M. Carmona ; Kumar, Christopher ; Costa, Helena ; Haider, Aiman ; Freeman, Alex ; Jameson, Charles ; Ratynska, Marzena ; Ben-Salha, Imen ; Sridhar, Ashwin ; Shaw, Greg ; Kelly, John D. ; Pye, Hayley ; Gately, Kathy A. ; Whitaker, Hayley C. ; Heavey, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.14380-12, Article 14380
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The oncological relevance of fragile sites in cancer
Author / Creator:Simpson, Benjamin S. ; Pye, Hayley ; Whitaker, Hayley C.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-05, Vol.4 (1), p.567-567, Article 567
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Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis
Author / Creator:Zhao, Yi ; Morka, Naomi ; Simpson, Benjamin Scott S ; Freeman, Alex ; Kirkham, Alex ; Kelly, Daniel ; Whitaker, Hayley C ; Emberton, Mark ; Norris, Joseph M
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2021-12, Vol.11 (12), p.e052277-e052277
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Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women
Author / Creator:Kelemen, Linda E ; Brenton, James D ; Parkinson, Christine ; C Whitaker, Hayley ; Piskorz, Anna M ; Csizmadi, Ilona ; Robson, Paula J
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-05, Vol.9 (5), p.e96542-e96542
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Clinical outcomes associated with prostate cancer conspicuity on biparametric and multiparametric MRI: a protocol for a systematic review and meta-analysis of biochemical recurrence following radical...
Author / Creator:Morka, Naomi ; Simpson, Benjamin S ; Ball, Rhys ; Freeman, Alex ; Kirkham, Alex ; Kelly, Daniel ; Whitaker, Hayley C ; Emberton, Mark ; Norris, Joseph M
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2021-05, Vol.11 (5), p.e047664-e047664
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Genetic landscape of prostate cancer conspicuity on multiparametric MRI: a protocol for a systematic review and bioinformatic analysis
Author / Creator:Norris, Joseph M ; Simpson, Benjamin S ; Parry, Marina A ; Allen, Clare ; Ball, Rhys ; Freeman, Alex ; Kelly, Daniel ; Kirkham, Alex ; Kasivisvanathan, Veeru ; Whitaker, Hayley C ; Emberton, Mark
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2020-01, Vol.10 (1), p.e034611-e034611
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Histopathological features of prostate cancer conspicuity on multiparametric MRI: protocol for a systematic review and meta-analysis
Author / Creator:Norris, Joseph M ; Carmona Echeverria, Lina M ; Simpson, Benjamin S ; Ball, Rhys ; Freeman, Alex ; Kelly, Daniel ; Kirkham, Alex ; Whitaker, Hayley C ; Emberton, Mark
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2020-10, Vol.10 (10), p.e039735-e039735
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The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine
Author / Creator:Whitaker, Hayley C ; Kote-Jarai, Zsofia ; Ross-Adams, Helen ; Warren, Anne Y ; Burge, Johanna ; George, Anne ; Bancroft, Elizabeth ; Jhavar, Sameer ; Leongamornlert, Daniel ; Tymrakiewicz, Malgorzata ; Saunders, Edward ; Page, Elizabeth ; Mitra, Anita ; Mitchell, Gillian ; Lindeman, Geoffrey J ; Evans, D Gareth ; Blanco, Ignacio ; Mercer, Catherine ; Rubinstein, Wendy S ; Clowes, Virginia ; Douglas, Fiona ; Hodgson, Shirley ; Walker, Lisa ; Donaldson, Alan ; Izatt, Louise ; Dorkins, Huw ; Male, Alison ; Tucker, Kathy ; Stapleton, Alan ; Lam, Jimmy ; Kirk, Judy ; Lilja, Hans ; Easton, Douglas ; Cooper, Colin ; Eeles, Rosalind ; Neal, David E
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-10, Vol.5 (10), p.e13363-e13363
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Exploring Patient Views and Acceptance of Multiparametric Magnetic Resonance Imaging for the Investigation of Suspected Prostate Cancer (the PACT Study): A Mixed-Methods Study Protocol
Author / Creator:Norris, Joseph M ; Kasivisvanathan, Veeru ; Allen, Clare ; Ball, Rhys ; Freeman, Alex ; Ghei, Maneesh ; Kirkham, Alex ; Whitaker, Hayley C ; Kelly, Daniel ; Emberton, Mark
Publisher:Switzerland: MDPI AG
Journal title:Methods and protocols, 2020-03, Vol.3 (2), p.26
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Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
Author / Creator:Cooper, Colin S ; Eeles, Rosalind ; Wedge, David C ; Van Loo, Peter ; Gundem, Gunes ; Alexandrov, Ludmil B ; Kremeyer, Barbara ; Butler, Adam ; Lynch, Andrew G ; Camacho, Niedzica ; Massie, Charlie E ; Kay, Jonathan ; Luxton, Hayley J ; Edwards, Sandra ; Kote-Jarai, Zsofia ; Dennis, Nening ; Merson, Sue ; Leongamornlert, Daniel ; Zamora, Jorge ; Corbishley, Cathy ; Thomas, Sarah ; Nik-Zainal, Serena ; Ramakrishna, Manasa ; O'Meara, Sarah ; Matthews, Lucy ; Clark, Jeremy ; Hurst, Rachel ; Mithen, Richard ; Bristow, Robert G ; Boutros, Paul C ; Fraser, Michael ; Cooke, Susanna ; Raine, Keiran ; Jones, David ; Menzies, Andrew ; Stebbings, Lucy ; Hinton, Jon ; Teague, Jon ; McLaren, Stuart ; Mudie, Laura ; Hardy, Claire ; Anderson, Elizabeth ; Joseph, Olivia ; Goody, Victoria ; Robinson, Ben ; Maddison, Mark ; Gamble, Stephen ; Greenman, Christopher ; Berney, Dan ; Hazell, Steven ; Livni, Naomi ; Fisher, Cyril ; Ogden, Christopher ; Kumar, Pardeep ; Thompson, Alan ; Woodhouse, Christopher ; Nicol, David ; Mayer, Erik ; Dudderidge, Tim ; Shah, Nimish C ; Gnanapragasam, Vincent ; Voet, Thierry ; Campbell, Peter ; Futreal, Andrew ; Easton, Douglas ; Warren, Anne Y ; Foster, Christopher S ; Stratton, Michael R ; Whitaker, Hayley C ; McDermott, Ultan ; Brewer, Daniel S ; Neal, David E
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2015-04, Vol.47 (4), p.367-372
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Mutational signatures of ionizing radiation in second malignancies
Author / Creator:Behjati, Sam ; Gundem, Gunes ; Wedge, David C. ; Roberts, Nicola D. ; Tarpey, Patrick S. ; Cooke, Susanna L. ; Van Loo, Peter ; Alexandrov, Ludmil B. ; Ramakrishna, Manasa ; Davies, Helen ; Nik-Zainal, Serena ; Hardy, Claire ; Latimer, Calli ; Raine, Keiran M. ; Stebbings, Lucy ; Menzies, Andy ; Jones, David ; Shepherd, Rebecca ; Butler, Adam P. ; Teague, Jon W. ; Jorgensen, Mette ; Khatri, Bhavisha ; Pillay, Nischalan ; Shlien, Adam ; Futreal, P. Andrew ; Badie, Christophe ; McDermott, Ultan ; Bova, G. Steven ; Richardson, Andrea L. ; Flanagan, Adrienne M. ; Stratton, Michael R. ; Campbell, Peter J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-09, Vol.7 (1), p.12605-8, Article 12605
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Asporin is a stromally expressed marker associated with prostate cancer progression
Author / Creator:Rochette, Annie ; Boufaied, Nadia ; Scarlata, Eleonora ; Hamel, Lucie ; Brimo, Fadi ; Whitaker, Hayley C ; Ramos-Montoya, Antonio ; Neal, David E ; Dragomir, Alice ; Aprikian, Armen ; Chevalier, Simone ; Thomson, Axel A
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2017-03, Vol.116 (6), p.775-784
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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer
Author / Creator:Luszczak, Sabina ; Kumar, Christopher ; Sathyadevan, Vignesh Krishna ; Simpson, Benjamin S ; Gately, Kathy A ; Whitaker, Hayley C ; Heavey, Susan
Publisher:England: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2020-01, Vol.5 (1), p.7
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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
Author / Creator:Ju, Young Seok ; Alexandrov, Ludmil B ; Gerstung, Moritz ; Martincorena, Inigo ; Nik-Zainal, Serena ; Ramakrishna, Manasa ; Davies, Helen R ; Papaemmanuil, Elli ; Gundem, Gunes ; Shlien, Adam ; Bolli, Niccolo ; Behjati, Sam ; Tarpey, Patrick S ; Nangalia, Jyoti ; Massie, Charles E ; Butler, Adam P ; Teague, Jon W ; Vassiliou, George S ; Green, Anthony R ; Du, Ming-Qing ; Unnikrishnan, Ashwin ; Pimanda, John E ; Teh, Bin Tean ; Munshi, Nikhil ; Greaves, Mel ; Vyas, Paresh ; El-Naggar, Adel K ; Santarius, Tom ; Collins, V Peter ; Grundy, Richard ; Taylor, Jack A ; Hayes, D Neil ; Malkin, David ; Foster, Christopher S ; Warren, Anne Y ; Whitaker, Hayley C ; Brewer, Daniel ; Eeles, Rosalind ; Cooper, Colin ; Neal, David ; Visakorpi, Tapio ; Isaacs, William B ; Bova, G Steven ; Flanagan, Adrienne M ; Futreal, P Andrew ; Lynch, Andy G ; Chinnery, Patrick F ; McDermott, Ultan ; Stratton, Michael R ; Campbell, Peter J
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-10, Vol.3
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ArticlesPeer ReviewedFull Text
PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer
Author / Creator:Luszczak, Sabina ; Kumar, Christopher ; Sathyadevan, Vignesh Krishna ; Simpson, Benjamin S. ; Gately, Kathy A. ; Whitaker, Hayley C. ; Heavey, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2020-01, Vol.5 (1), p.7-7, Article 7
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The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing
Author / Creator:Luxton, Hayley J ; Simpson, Benjamin S ; Mills, Ian G ; Brindle, Nicola R ; Ahmed, Zeba ; Stavrinides, Vasilis ; Heavey, Susan ; Stamm, Stefan ; Whitaker, Hayley C
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-08, Vol.11 (9), p.1233
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The evolutionary history of lethal metastatic prostate cancer

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Joint estimation of relaxation and diffusion tissue parameters for prostate cancer with relaxation-VERDICT MRI

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Use of artificial intelligence in the detection of primary prostate cancer in multiparametric MRI with its clinical outcomes: a protocol for a systematic review and meta-analysis

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The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

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Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer

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The oncological relevance of fragile sites in cancer

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Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis

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Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women

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Clinical outcomes associated with prostate cancer conspicuity on biparametric and multiparametric MRI: a protocol for a systematic review and meta-analysis of biochemical recurrence following radical...

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Genetic landscape of prostate cancer conspicuity on multiparametric MRI: a protocol for a systematic review and bioinformatic analysis

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Histopathological features of prostate cancer conspicuity on multiparametric MRI: protocol for a systematic review and meta-analysis

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The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

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Exploring Patient Views and Acceptance of Multiparametric Magnetic Resonance Imaging for the Investigation of Suspected Prostate Cancer (the PACT Study): A Mixed-Methods Study Protocol

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Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

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Mutational signatures of ionizing radiation in second malignancies

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Asporin is a stromally expressed marker associated with prostate cancer progression

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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

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PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

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The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing

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