Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived...
Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Gastrointestinal symptoms in COVID-19 are associated with prolonged symptoms and increased severity. We employed human intestinal organoids derived from pluripotent stem cells (PSC-HIOs) to analyze SARS-CoV-2 pathogenesis and to validate efficacy of specific drugs in the gut. Certain, but not all cell types in PSC-HIOs express SARS-CoV-2 entry fact...
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Full title
Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids
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TN_cdi_proquest_journals_2411938504
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2411938504
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E-ISSN
2692-8205
DOI
10.1101/2020.06.10.144816
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https://www.proquest.com/docview/2411938504?pq-origsite=primo&accountid=13902
