Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulat...
Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain
About this item
Full title
Author / Creator
Zhang, Jinwei , Gao, Geng , Begum, Gulnaz , Wang, Jinhua , Khanna, Arjun R. , Shmukler, Boris E. , Daubner, Gerrit M. , de los Heros, Paola , Davies, Paul , Varghese, Joby , Bhuiyan, Mohammad Iqbal H. , Duan, Jinjing , Zhang, Jin , Duran, Daniel , Alper, Seth L. , Sun, Dandan , Elledge, Stephen J. , Alessi, Dario R. and Kahle, Kristopher T.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cell volume homeostasis requires the dynamically regulated transport of ions across the plasmalemma. While the ensemble of ion transport proteins involved in cell volume regulation is well established, the molecular coordinators of their activities remain poorly characterized. We utilized a functional kinomics approach including a kinome-wide siRNA...
Alternative Titles
Full title
Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain
Authors, Artists and Contributors
Author / Creator
Gao, Geng
Begum, Gulnaz
Wang, Jinhua
Khanna, Arjun R.
Shmukler, Boris E.
Daubner, Gerrit M.
de los Heros, Paola
Davies, Paul
Varghese, Joby
Bhuiyan, Mohammad Iqbal H.
Duan, Jinjing
Zhang, Jin
Duran, Daniel
Alper, Seth L.
Sun, Dandan
Elledge, Stephen J.
Alessi, Dario R.
Kahle, Kristopher T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5080614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5080614
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep35986
